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The map label for this gene is cutM [H]

Identifier: 119714489

GI number: 119714489

Start: 238856

End: 239734

Strand: Direct

Name: cutM [H]

Synonym: Noca_0222

Alternate gene names: 119714489

Gene position: 238856-239734 (Clockwise)

Preceding gene: 119714488

Following gene: 119714490

Centisome position: 4.79

GC content: 73.61

Gene sequence:

>879_bases
GTGCAGGTACCGGCGCCGATCGAATACGAGCGGGCGACCAGTGTCGAGCACGCGATCGGGCTGCTGGCCCGGCTCGGGGA
CGAGGCGCGGCTGATCGCCGGCGGGCACAGCCTGCTGCCGATGATGAAGCTGCGGCTGGCCAACCCCGAGTACCTCGTCG
ACATCAACGACCTGCACGACGAGCTCAGCTACATCGACATCGGCCCGACCGGGGTGCGCATCGGTGCGCTGACCCGCCAC
CGCGAGCTGCTCGAGTCCGATGCCCTCGCCGAGGTGTGCCCGATCTTCCGGGACGCCGAGCGGGTGATCGCCGACCCGCC
CGTCCGCAACCGCGGCACGCTCGGCGGTGCGCTGTGCCAGGCAGACCCGTCGGAGGACCTGTCCTCGGTGTGCACCACGC
TCGACGCGAGCTGCGTGATCCGCGGCCGGGACGGCGAGCGGGTGGTGTCCATGGACGACTTCCACCTCGGGCCGTACGAG
ACCGTCGTCCGGCACGACGAGATGCTGATCGAGGTGCGCATCCCGGTCCGCCCGCACGGCAGCAGCGCCTATGCGAAGGT
CGATCGCCGCGCCGGCGACTGGGCGGTCACCGCCGTCGGCGCGGCGCTCTGGCTCGACGAGCACGACTCGATCGCCGATG
CCCGGGTCGGGCTGGCCGCGGTGGGGCCGAACACCACCGGCATCCCCGCGATCTCCGCGGCGCTGCGGGGCCGGGCGCCG
AGCGAGGAGGCCTGGGCCGAGGCCGGGGCGATCGCGGCGGCCAGCTGCCGACCGGTCACCGACGGCCGCGGGAGCGCGGA
CTACAAGCGCCACCTGGCCGGGGAGCTCACCCGGCGTACGCTGCGCACGGCCTGGGAGCGGGTGGTCACGTGGAGGTGA

Upstream 100 bases:

>100_bases
CGTCACCGCCCGCCGCCGCGCACACCGACGGCCCGGGGGGACACCGATCGCCCCGGACGATTTCCCACCCGCGGGGGTCG
CTCGCCGTACCATCGGCCGC

Downstream 100 bases:

>100_bases
CCCTCACGGTGAACGGCGAGGTCGTCACCCGCGACGTGGAGGCGCGCCTGCTGCTCGTGCACTTCCTGCGCGACGACCTC
GGCCTGACCGGTACGCACTG

Product: molybdopterin dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MQVPAPIEYERATSVEHAIGLLARLGDEARLIAGGHSLLPMMKLRLANPEYLVDINDLHDELSYIDIGPTGVRIGALTRH
RELLESDALAEVCPIFRDAERVIADPPVRNRGTLGGALCQADPSEDLSSVCTTLDASCVIRGRDGERVVSMDDFHLGPYE
TVVRHDEMLIEVRIPVRPHGSSAYAKVDRRAGDWAVTAVGAALWLDEHDSIADARVGLAAVGPNTTGIPAISAALRGRAP
SEEAWAEAGAIAAASCRPVTDGRGSADYKRHLAGELTRRTLRTAWERVVTWR

Sequences:

>Translated_292_residues
MQVPAPIEYERATSVEHAIGLLARLGDEARLIAGGHSLLPMMKLRLANPEYLVDINDLHDELSYIDIGPTGVRIGALTRH
RELLESDALAEVCPIFRDAERVIADPPVRNRGTLGGALCQADPSEDLSSVCTTLDASCVIRGRDGERVVSMDDFHLGPYE
TVVRHDEMLIEVRIPVRPHGSSAYAKVDRRAGDWAVTAVGAALWLDEHDSIADARVGLAAVGPNTTGIPAISAALRGRAP
SEEAWAEAGAIAAASCRPVTDGRGSADYKRHLAGELTRRTLRTAWERVVTWR
>Mature_292_residues
MQVPAPIEYERATSVEHAIGLLARLGDEARLIAGGHSLLPMMKLRLANPEYLVDINDLHDELSYIDIGPTGVRIGALTRH
RELLESDALAEVCPIFRDAERVIADPPVRNRGTLGGALCQADPSEDLSSVCTTLDASCVIRGRDGERVVSMDDFHLGPYE
TVVRHDEMLIEVRIPVRPHGSSAYAKVDRRAGDWAVTAVGAALWLDEHDSIADARVGLAAVGPNTTGIPAISAALRGRAP
SEEAWAEAGAIAAASCRPVTDGRGSADYKRHLAGELTRRTLRTAWERVVTWR

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=282, Percent_Identity=28.0141843971631, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789245, Length=272, Percent_Identity=30.1470588235294, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 31590; Mature: 31590

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVPAPIEYERATSVEHAIGLLARLGDEARLIAGGHSLLPMMKLRLANPEYLVDINDLHD
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCEEEECHHHHC
ELSYIDIGPTGVRIGALTRHRELLESDALAEVCPIFRDAERVIADPPVRNRGTLGGALCQ
CCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEC
ADPSEDLSSVCTTLDASCVIRGRDGERVVSMDDFHLGPYETVVRHDEMLIEVRIPVRPHG
CCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCHHHHHHHCCEEEEEEEECCCCCC
SSAYAKVDRRAGDWAVTAVGAALWLDEHDSIADARVGLAAVGPNTTGIPAISAALRGRAP
CCHHHHHHCCCCCCHHHHHHHHHEECCCCCHHHHHCCEEEECCCCCCCHHHHHHHCCCCC
SEEAWAEAGAIAAASCRPVTDGRGSADYKRHLAGELTRRTLRTAWERVVTWR
CHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQVPAPIEYERATSVEHAIGLLARLGDEARLIAGGHSLLPMMKLRLANPEYLVDINDLHD
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCEEEECHHHHC
ELSYIDIGPTGVRIGALTRHRELLESDALAEVCPIFRDAERVIADPPVRNRGTLGGALCQ
CCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEC
ADPSEDLSSVCTTLDASCVIRGRDGERVVSMDDFHLGPYETVVRHDEMLIEVRIPVRPHG
CCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCHHHHHHHCCEEEEEEEECCCCCC
SSAYAKVDRRAGDWAVTAVGAALWLDEHDSIADARVGLAAVGPNTTGIPAISAALRGRAP
CCHHHHHHCCCCCCHHHHHHHHHEECCCCCHHHHHCCEEEECCCCCCCHHHHHHHCCCCC
SEEAWAEAGAIAAASCRPVTDGRGSADYKRHLAGELTRRTLRTAWERVVTWR
CHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]