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The map label for this gene is hsaB [H]

Identifier: 119714488

GI number: 119714488

Start: 237463

End: 238644

Strand: Direct

Name: hsaB [H]

Synonym: Noca_0221

Alternate gene names: 119714488

Gene position: 237463-238644 (Clockwise)

Preceding gene: 119714487

Following gene: 119714489

Centisome position: 4.76

GC content: 74.7

Gene sequence:

>1182_bases
ATGAGCGACCCGAACCCGGCCCACTTCCGGCAGGTGCTGGGCCAGTACCCCACCGGTGTCGCGGTGGTGACCGCGCTCGA
CGAGTCCGGTGCCCCGCTCGGGATGACGGTCGGCTCCTTCACCTCGGTCTCGCTCGACCCGCCGCTCGTGGCGTTCCTGC
CCGACCAGGGGTCCAGCTCGTGGCGCGCGCTGCGCGCCTCCGGCGACCGGTTCTGCGTCAACGTCCTCGGCGCCGACCAG
GAGGACGTGTGCCGCGCGATCGCGGTCCGCAAGGTCGACAAGTTCGCGGGCATCCCGTGGCGGCCGTCGCCGGCCGGCAA
CCCGGTGATCGACGGCGCGGTCGCGTACCTCGACTGCACGACCGAGCAGGTCCACGACGCCGGCGACCACCACATCGTCG
TCGGTCGGGTGCACCAGCTCGACCTGGTCGGCGGCGACCAGCCGTTGCTGTTCTTCCGCGGCGGTTATGGCTCGTTCACC
CCGCTCTCGCTGGCCTCGGGCGACAGCGACCTGCTCGACCACCTGCGCCTCGTCGACCTGGCCCGGCCGCAGATGGACCG
GCTCGCGGCCCGCTTCGACACCGAGGTCACCGCGATCGCGCTGGTGCGCGACGAGCTGGTGCTGGCGGCCGCGGCCGGCC
GCACCCGGCTCGCCGTCGCGCCGACCCGGGTGGGGCAGCGGTTGCCGTTCATGCCGCCGCTGGGCAGCTGCTTCGCCGGT
TGGGGCGACGACGCGGTCCGCGCCGCGTGGGTGGGCGGCCTCTCGGACCTGGTCGACCCCGACACCCGGGACGCCGTACG
CGCGGTGCCCGGACTGGTGCGTCGCCGCGGCTACTCGATCGCACTCGGCCACGGCGACGGTGCCCGCCTCGAGACGCTGA
GCACCCGCTTCCACGAGGGCGACGCCCAGGTCTCCAAGGCCGCCCTGCGCGAGGCGATCGCGCAGAGCGTCTCCGGCTAC
AACCCCGCGTCGTACGGCGCCGGGCCGGTCGAGCTCCGCTCGCTGAGCGCACCGGTGTTCGCCAACGACGGCCGGGTCGC
GTTCACCCTCACGCTCTGGGGGCCGCCCGGCGCCATCGACGCCGCCGAGGTCGACCGCCACGTCGAGGAGCTGCTCGCCG
CGACCGGCGCCGCGACGATCGCCATCGACGGCCGGGTCCCCCTCGACGCCGCCATCGCCTGA

Upstream 100 bases:

>100_bases
CGCCGCGTCGGCCCGCGTGACGCCGAGGTGAGCCCTTGCACAGTCTGCAGTCGTGTGCGACAGTCGTCCCTGTAGTGATC
GTTACAGAGAGGACGAGCCG

Downstream 100 bases:

>100_bases
CGTCTCGCCCCGGCAGCCGCGGGGGGTTTCCCCGGTTAACCGGGGAAACCGGAACCGTTGGGCCGAAACTTCGGGGCAGA
AGTTCCAACTTCCCCGGTTA

Product: flavin reductase domain-containing protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSDPNPAHFRQVLGQYPTGVAVVTALDESGAPLGMTVGSFTSVSLDPPLVAFLPDQGSSSWRALRASGDRFCVNVLGADQ
EDVCRAIAVRKVDKFAGIPWRPSPAGNPVIDGAVAYLDCTTEQVHDAGDHHIVVGRVHQLDLVGGDQPLLFFRGGYGSFT
PLSLASGDSDLLDHLRLVDLARPQMDRLAARFDTEVTAIALVRDELVLAAAAGRTRLAVAPTRVGQRLPFMPPLGSCFAG
WGDDAVRAAWVGGLSDLVDPDTRDAVRAVPGLVRRRGYSIALGHGDGARLETLSTRFHEGDAQVSKAALREAIAQSVSGY
NPASYGAGPVELRSLSAPVFANDGRVAFTLTLWGPPGAIDAAEVDRHVEELLAATGAATIAIDGRVPLDAAIA

Sequences:

>Translated_393_residues
MSDPNPAHFRQVLGQYPTGVAVVTALDESGAPLGMTVGSFTSVSLDPPLVAFLPDQGSSSWRALRASGDRFCVNVLGADQ
EDVCRAIAVRKVDKFAGIPWRPSPAGNPVIDGAVAYLDCTTEQVHDAGDHHIVVGRVHQLDLVGGDQPLLFFRGGYGSFT
PLSLASGDSDLLDHLRLVDLARPQMDRLAARFDTEVTAIALVRDELVLAAAAGRTRLAVAPTRVGQRLPFMPPLGSCFAG
WGDDAVRAAWVGGLSDLVDPDTRDAVRAVPGLVRRRGYSIALGHGDGARLETLSTRFHEGDAQVSKAALREAIAQSVSGY
NPASYGAGPVELRSLSAPVFANDGRVAFTLTLWGPPGAIDAAEVDRHVEELLAATGAATIAIDGRVPLDAAIA
>Mature_392_residues
SDPNPAHFRQVLGQYPTGVAVVTALDESGAPLGMTVGSFTSVSLDPPLVAFLPDQGSSSWRALRASGDRFCVNVLGADQE
DVCRAIAVRKVDKFAGIPWRPSPAGNPVIDGAVAYLDCTTEQVHDAGDHHIVVGRVHQLDLVGGDQPLLFFRGGYGSFTP
LSLASGDSDLLDHLRLVDLARPQMDRLAARFDTEVTAIALVRDELVLAAAAGRTRLAVAPTRVGQRLPFMPPLGSCFAGW
GDDAVRAAWVGGLSDLVDPDTRDAVRAVPGLVRRRGYSIALGHGDGARLETLSTRFHEGDAQVSKAALREAIAQSVSGYN
PASYGAGPVELRSLSAPVFANDGRVAFTLTLWGPPGAIDAAEVDRHVEELLAATGAATIAIDGRVPLDAAIA

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 41277; Mature: 41146

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPNPAHFRQVLGQYPTGVAVVTALDESGAPLGMTVGSFTSVSLDPPLVAFLPDQGSSS
CCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCEEEECCCCEEEEECCCCCCC
WRALRASGDRFCVNVLGADQEDVCRAIAVRKVDKFAGIPWRPSPAGNPVIDGAVAYLDCT
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
TEQVHDAGDHHIVVGRVHQLDLVGGDQPLLFFRGGYGSFTPLSLASGDSDLLDHLRLVDL
HHHHHCCCCCEEEEEEEEEEEEECCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHH
ARPQMDRLAARFDTEVTAIALVRDELVLAAAAGRTRLAVAPTRVGQRLPFMPPLGSCFAG
CCCHHHHHHHHHCCCCEEEEEEHHHEEEEECCCCCEEEECHHHHCCCCCCCCCCHHHHCC
WGDDAVRAAWVGGLSDLVDPDTRDAVRAVPGLVRRRGYSIALGHGDGARLETLSTRFHEG
CCCHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCC
DAQVSKAALREAIAQSVSGYNPASYGAGPVELRSLSAPVFANDGRVAFTLTLWGPPGAID
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCCEEEEEEEEECCCCCCC
AAEVDRHVEELLAATGAATIAIDGRVPLDAAIA
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCC
>Mature Secondary Structure 
SDPNPAHFRQVLGQYPTGVAVVTALDESGAPLGMTVGSFTSVSLDPPLVAFLPDQGSSS
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCEEEECCCCEEEEECCCCCCC
WRALRASGDRFCVNVLGADQEDVCRAIAVRKVDKFAGIPWRPSPAGNPVIDGAVAYLDCT
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
TEQVHDAGDHHIVVGRVHQLDLVGGDQPLLFFRGGYGSFTPLSLASGDSDLLDHLRLVDL
HHHHHCCCCCEEEEEEEEEEEEECCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHH
ARPQMDRLAARFDTEVTAIALVRDELVLAAAAGRTRLAVAPTRVGQRLPFMPPLGSCFAG
CCCHHHHHHHHHCCCCEEEEEEHHHEEEEECCCCCEEEECHHHHCCCCCCCCCCHHHHCC
WGDDAVRAAWVGGLSDLVDPDTRDAVRAVPGLVRRRGYSIALGHGDGARLETLSTRFHEG
CCCHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCC
DAQVSKAALREAIAQSVSGYNPASYGAGPVELRSLSAPVFANDGRVAFTLTLWGPPGAID
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCCEEEEEEEEECCCCCCC
AAEVDRHVEELLAATGAATIAIDGRVPLDAAIA
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA