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The map label for this gene is helD [H]

Identifier: 119714480

GI number: 119714480

Start: 228226

End: 230379

Strand: Direct

Name: helD [H]

Synonym: Noca_0213

Alternate gene names: 119714480

Gene position: 228226-230379 (Clockwise)

Preceding gene: 119714478

Following gene: 119714486

Centisome position: 4.58

GC content: 74.65

Gene sequence:

>2154_bases
ATGGAGCCAACGACCACCAGCGCGTTCGACCTTCCGGCGCACCTCGCCGCCAAGGCCGACCCGGGACTGATCGGCCGCGA
CGAACGGCACTTCGCGGCGATCGCGGAGAGCTTGAAGGTCACCATCGCCGAGCTGACGGACCGGCTCGACGCGGCCCGCC
GGGCACCGGGCGGCAACGGCCAGGAGGCGTTGGAGCGCGACCAGGAGGTCCACCGGCTGACCGCCCGGCTCCGCGCCCTG
CGCCGCTACGGCCTCGACCTCTGCCTCGGGCACGTCGTCGGCGCTGACGACGGCGAGCCGGCGTACGTCGGCCGGCTCGG
CCTCACCGACACGGCGGGACGCCGGCTCCTGCTGGACTGGCGCTCGCCGGCGGCCGAGCCGTTCTTCGGCGCCACCCACG
CCAACCCGATGGGCCTGGCGAGCCGGCGCCGGTACCGCTGGACCCGCGGCCGGGTCACCGACTACTGGGACGAGGTCTTC
ACCGCGGACGGCCTCGACGGCCACGCGGCGGCGCTGGACGACCAGTCGGCGTTCATCGCCAGCCTCGGCGCGACCCGCTC
GCCGCGGATGCGCGACGTGCTCGGAACCATCCAGGCCGACCAGGACGCGATCATCCGCGCGAGCTCGCGCGGAGCGCTGG
TCGTCGACGGTGGACCGGGCACGGGGAAGACCGTCGTCGCGCTGCACCGCACCGCCTACCTCCTGTACGCCGACCCGCGC
CTGGGCCACCGCCGCGGCGGCGTGCTCTTCGTCGGGCCGCACCAGCCCTACCTCGCCTACGTCTCCGACGTGCTGCCCAG
CCTCGGGGAGGAAGGGGTACAGACCGCGACCGTGGGCGACCTCGTGCCCGAGGGCGCCACCGCGCCGCCCGAGGCCGACC
CGGCGGTCGCCCGGCTGAAGGCGTCGGCCCGGATGGTGGCGGCGATCGAGCCCGCCGTCCGGCTCTACGAGGAGCTGCCG
ACCGAGGGCATGGCGGTCGAGACGCCGTACGCCGACCTGTGGGTGAGCGTCGAGGACTGGGCCGAGGCGTTCGGTGCGGC
GGACCCGGCGCTCCCGCACAACGAGGCCCGCGACGACGTGTGGCTGGCGCTGGTCGCGATCCTCCTCGACAAGGCCGACC
CCGACGACGTGCCGGTCGACCGGCTCCGCCGTTCCCTGGCGCACCACGAGGGGCTGGTCAGCGCCTTCGACCGGGCGTGG
ACCGTGATCGACCCGTACGACCTGGTCGGTGACCTGTGGTCGGTGCCGGCGTACCTCCGCCGCTGCGCACCCTGGCTCGA
GCCGGACGAGGTGCGGCTGCTGCAGCGCGCGGACGCCCAGGCATGGACGGTCTCCGACCTGCCCCTGCTCGACGCGGCCC
GGCAGCAGCTCGGCGATCCCGGGGCGTCCCGGCGCCGACGCCGGCGGGAGGCGGCGCTCCAGGCGCAGGCGGAGGAGATG
TCGCACGTGGTCGACCACCTGATCGCCACCGACGACTCCGAGATGCAGGTGATGTCCATGCTGCGCGTCGAGGACCTGCA
GGGCGCGCTGGTCGACGAGGACGTCGTCCCGGCTGCGGACCCGGACCAGCTGGCCGGTCCGTTCGCGCACGTCGTCGTGG
ACGAGGCGCAGGAGCTGACCGATGCCGAGTGGCAGATGCTCCTGCTGCGCTGCCCCTCGCGCAGCCTCACCGTGGTCGGT
GACCGGGCCCAGGCCCGGCACGGGTTCGCCGAGAGCTGGCAGGAGCGGCTCCAGCGGATCGGCCTCGACCGGGTCGAGGT
CGCGGCGCTGAACCTCAACTACCGGACCCCCGCGGAGGTGATGGCCGAGGCCGAGCCGGTGATCCGGGCGGCGCTCCCTG
ACGCCAACGTGCCGACGTCGGTGCGCAGGTCCGGGATCCCGGTCCACCACGGGTCCGTGGCGGACCTGGAGGTGATCGTG
GACGACTGGCTGGCCGAGCACGCCGAGGGGACCGTGTGCATCGTCGGCGACCACCCGCTCGCGCCCCGGCCCCGGGTCCG
CTCGCTGGCCCCGGAGCTGGTGAAGGGCCTGGAGTTCGACCTCGTCGTCCTGGTCGACCCGGGCCGCTTCGGCGACGGCG
TCGAGGGCGCGGTCGACCGCTACGTCGCGATGACCCGGGCGACCCAGCGGCTGGTGCTGCTCACGAGCCGGTGA

Upstream 100 bases:

>100_bases
CACCATCAACGTATAACGCACCGAGGGGCTTGCGGCAAGGCCCCCGACCGGGCGCAGAATCTCCCGCCGTAGCCGAGCAG
CCGACGGGGGAGCACGAGGC

Downstream 100 bases:

>100_bases
GGCCGCCGGCCGTCGGTACGCCGCGGTCCCGGTGTCGGTGCCGGGGTCGGTCGGGTCCGGCCGCCGACGGCTCGGGCGGG
TGCCGCTCGGCGCGCAGCAG

Product: superfamily I DNA and RNA helicases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 717

Protein sequence:

>717_residues
MEPTTTSAFDLPAHLAAKADPGLIGRDERHFAAIAESLKVTIAELTDRLDAARRAPGGNGQEALERDQEVHRLTARLRAL
RRYGLDLCLGHVVGADDGEPAYVGRLGLTDTAGRRLLLDWRSPAAEPFFGATHANPMGLASRRRYRWTRGRVTDYWDEVF
TADGLDGHAAALDDQSAFIASLGATRSPRMRDVLGTIQADQDAIIRASSRGALVVDGGPGTGKTVVALHRTAYLLYADPR
LGHRRGGVLFVGPHQPYLAYVSDVLPSLGEEGVQTATVGDLVPEGATAPPEADPAVARLKASARMVAAIEPAVRLYEELP
TEGMAVETPYADLWVSVEDWAEAFGAADPALPHNEARDDVWLALVAILLDKADPDDVPVDRLRRSLAHHEGLVSAFDRAW
TVIDPYDLVGDLWSVPAYLRRCAPWLEPDEVRLLQRADAQAWTVSDLPLLDAARQQLGDPGASRRRRRREAALQAQAEEM
SHVVDHLIATDDSEMQVMSMLRVEDLQGALVDEDVVPAADPDQLAGPFAHVVVDEAQELTDAEWQMLLLRCPSRSLTVVG
DRAQARHGFAESWQERLQRIGLDRVEVAALNLNYRTPAEVMAEAEPVIRAALPDANVPTSVRRSGIPVHHGSVADLEVIV
DDWLAEHAEGTVCIVGDHPLAPRPRVRSLAPELVKGLEFDLVVLVDPGRFGDGVEGAVDRYVAMTRATQRLVLLTSR

Sequences:

>Translated_717_residues
MEPTTTSAFDLPAHLAAKADPGLIGRDERHFAAIAESLKVTIAELTDRLDAARRAPGGNGQEALERDQEVHRLTARLRAL
RRYGLDLCLGHVVGADDGEPAYVGRLGLTDTAGRRLLLDWRSPAAEPFFGATHANPMGLASRRRYRWTRGRVTDYWDEVF
TADGLDGHAAALDDQSAFIASLGATRSPRMRDVLGTIQADQDAIIRASSRGALVVDGGPGTGKTVVALHRTAYLLYADPR
LGHRRGGVLFVGPHQPYLAYVSDVLPSLGEEGVQTATVGDLVPEGATAPPEADPAVARLKASARMVAAIEPAVRLYEELP
TEGMAVETPYADLWVSVEDWAEAFGAADPALPHNEARDDVWLALVAILLDKADPDDVPVDRLRRSLAHHEGLVSAFDRAW
TVIDPYDLVGDLWSVPAYLRRCAPWLEPDEVRLLQRADAQAWTVSDLPLLDAARQQLGDPGASRRRRRREAALQAQAEEM
SHVVDHLIATDDSEMQVMSMLRVEDLQGALVDEDVVPAADPDQLAGPFAHVVVDEAQELTDAEWQMLLLRCPSRSLTVVG
DRAQARHGFAESWQERLQRIGLDRVEVAALNLNYRTPAEVMAEAEPVIRAALPDANVPTSVRRSGIPVHHGSVADLEVIV
DDWLAEHAEGTVCIVGDHPLAPRPRVRSLAPELVKGLEFDLVVLVDPGRFGDGVEGAVDRYVAMTRATQRLVLLTSR
>Mature_717_residues
MEPTTTSAFDLPAHLAAKADPGLIGRDERHFAAIAESLKVTIAELTDRLDAARRAPGGNGQEALERDQEVHRLTARLRAL
RRYGLDLCLGHVVGADDGEPAYVGRLGLTDTAGRRLLLDWRSPAAEPFFGATHANPMGLASRRRYRWTRGRVTDYWDEVF
TADGLDGHAAALDDQSAFIASLGATRSPRMRDVLGTIQADQDAIIRASSRGALVVDGGPGTGKTVVALHRTAYLLYADPR
LGHRRGGVLFVGPHQPYLAYVSDVLPSLGEEGVQTATVGDLVPEGATAPPEADPAVARLKASARMVAAIEPAVRLYEELP
TEGMAVETPYADLWVSVEDWAEAFGAADPALPHNEARDDVWLALVAILLDKADPDDVPVDRLRRSLAHHEGLVSAFDRAW
TVIDPYDLVGDLWSVPAYLRRCAPWLEPDEVRLLQRADAQAWTVSDLPLLDAARQQLGDPGASRRRRRREAALQAQAEEM
SHVVDHLIATDDSEMQVMSMLRVEDLQGALVDEDVVPAADPDQLAGPFAHVVVDEAQELTDAEWQMLLLRCPSRSLTVVG
DRAQARHGFAESWQERLQRIGLDRVEVAALNLNYRTPAEVMAEAEPVIRAALPDANVPTSVRRSGIPVHHGSVADLEVIV
DDWLAEHAEGTVCIVGDHPLAPRPRVRSLAPELVKGLEFDLVVLVDPGRFGDGVEGAVDRYVAMTRATQRLVLLTSR

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78116; Mature: 78116

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPTTTSAFDLPAHLAAKADPGLIGRDERHFAAIAESLKVTIAELTDRLDAARRAPGGNG
CCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QEALERDQEVHRLTARLRALRRYGLDLCLGHVVGADDGEPAYVGRLGLTDTAGRRLLLDW
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEEC
RSPAAEPFFGATHANPMGLASRRRYRWTRGRVTDYWDEVFTADGLDGHAAALDDQSAFIA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHH
SLGATRSPRMRDVLGTIQADQDAIIRASSRGALVVDGGPGTGKTVVALHRTAYLLYADPR
HHCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEEEEEEEECCC
LGHRRGGVLFVGPHQPYLAYVSDVLPSLGEEGVQTATVGDLVPEGATAPPEADPAVARLK
CCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHH
ASARMVAAIEPAVRLYEELPTEGMAVETPYADLWVSVEDWAEAFGAADPALPHNEARDDV
HHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHEEEHHHHHHHHCCCCCCCCCCCCHHHH
WLALVAILLDKADPDDVPVDRLRRSLAHHEGLVSAFDRAWTVIDPYDLVGDLWSVPAYLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHH
RCAPWLEPDEVRLLQRADAQAWTVSDLPLLDAARQQLGDPGASRRRRRREAALQAQAEEM
HCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SHVVDHLIATDDSEMQVMSMLRVEDLQGALVDEDVVPAADPDQLAGPFAHVVVDEAQELT
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHC
DAEWQMLLLRCPSRSLTVVGDRAQARHGFAESWQERLQRIGLDRVEVAALNLNYRTPAEV
CHHHHHHHHCCCCCCEEEEECHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHH
MAEAEPVIRAALPDANVPTSVRRSGIPVHHGSVADLEVIVDDWLAEHAEGTVCIVGDHPL
HHHCCHHHHHHCCCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
APRPRVRSLAPELVKGLEFDLVVLVDPGRFGDGVEGAVDRYVAMTRATQRLVLLTSR
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MEPTTTSAFDLPAHLAAKADPGLIGRDERHFAAIAESLKVTIAELTDRLDAARRAPGGNG
CCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QEALERDQEVHRLTARLRALRRYGLDLCLGHVVGADDGEPAYVGRLGLTDTAGRRLLLDW
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEEC
RSPAAEPFFGATHANPMGLASRRRYRWTRGRVTDYWDEVFTADGLDGHAAALDDQSAFIA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHH
SLGATRSPRMRDVLGTIQADQDAIIRASSRGALVVDGGPGTGKTVVALHRTAYLLYADPR
HHCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEEEEEEEECCC
LGHRRGGVLFVGPHQPYLAYVSDVLPSLGEEGVQTATVGDLVPEGATAPPEADPAVARLK
CCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHH
ASARMVAAIEPAVRLYEELPTEGMAVETPYADLWVSVEDWAEAFGAADPALPHNEARDDV
HHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHEEEHHHHHHHHCCCCCCCCCCCCHHHH
WLALVAILLDKADPDDVPVDRLRRSLAHHEGLVSAFDRAWTVIDPYDLVGDLWSVPAYLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHH
RCAPWLEPDEVRLLQRADAQAWTVSDLPLLDAARQQLGDPGASRRRRRREAALQAQAEEM
HCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SHVVDHLIATDDSEMQVMSMLRVEDLQGALVDEDVVPAADPDQLAGPFAHVVVDEAQELT
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHC
DAEWQMLLLRCPSRSLTVVGDRAQARHGFAESWQERLQRIGLDRVEVAALNLNYRTPAEV
CHHHHHHHHCCCCCCEEEEECHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHH
MAEAEPVIRAALPDANVPTSVRRSGIPVHHGSVADLEVIVDDWLAEHAEGTVCIVGDHPL
HHHCCHHHHHHCCCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
APRPRVRSLAPELVKGLEFDLVVLVDPGRFGDGVEGAVDRYVAMTRATQRLVLLTSR
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]