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The map label for this gene is celR [H]

Identifier: 119714463

GI number: 119714463

Start: 208506

End: 209549

Strand: Reverse

Name: celR [H]

Synonym: Noca_0196

Alternate gene names: 119714463

Gene position: 209549-208506 (Counterclockwise)

Preceding gene: 119714464

Following gene: 119714458

Centisome position: 4.2

GC content: 74.71

Gene sequence:

>1044_bases
ATGGCCAAGGTGACCCTCCAGTCGATCGCCGACCGCGTCGGCGTCAGCCGGATGACGGTCTCCAACGCGTTCTCCCGGCC
CGATCAGCTCTCCGGTGAGCTGCGCGAGCGGATCCTTGCGGCCGCCGACGAGCTCGGGTACGTCGGCCCCGACCCGGCCG
CACGCGCCCTCGCCCGGGGCCGGACCGGCTCGGTCGGCCTGCTGCTCACCGACGAGCTCGGCGAGGCGTTCCAGGACGCC
GTCGCGACCCAGTTTTTGACCTCGGTCGCCGACGCGCTCACCCACGAGGGGCTGGCCGTCACGCTGCTCACCTCGGGTGG
CGCGGCCGGGGCGCCGTCGGACTACGTGCCGGCCCGCGACGTCGCGATGGACGGCGCGATCGTCTACATCTGCGACCCCG
CCTCGCCCGACATCGCGTGGCTCGAGCGGCGCGGCCTGCCGCTGGTCTCCGTCGACCGCGAGCCGGCCCCGGACGCCCCC
AGTGTCAACGTCGACGACCGCGCGGGGGCCCGCGCGGCGGCCGAGCACCTGATCGAGCTCGGGCACACGCGGGTCGCGAT
CATCACCCTGCGCAGCACCTTCGACGTCGCCGGGGTGCCGACGGCCAACCGGCCCGCCAGCGAGCGGATGACCGGCTGGC
GCGAGGCCCTCGAGGCCGCCGGCATCGAGCCGGTGGTGGCCGCCGCCGCCTTCCGGCCCCGGCCCTCGGTCGAGGAGATC
GCGCGCGACCTGCTCGACCGGCCGGACCGTCCGACCGCGGTGCTGTGCTTCTCCGACGCGTTCGCGGTCACCACGATCCA
GGTCGCGGAGTCACTGGGCCTGCGCGTGCCCGAGGACCTGTCGGTGGTCGGGTACGACGACTCCCCGCTCGCGACAGCCA
TCCGGCCTCAGCTCACCACCGTGCACCAGGAGGTGGCCAGGAAGGGTCAGGAGGCGGTGCGCTCCCTGATGGCGATCATG
GGGCCGGACCGTCCGGACCCGGTCGAGCGGATCCTGCTGCCGACCGCGCTCGTGGTGCGCGACAGCACCGCGCCGCCGCC
CTGA

Upstream 100 bases:

>100_bases
TCGCCCGCTGGGTGGAGCCGCGGCCCACCGAGGCCTGCCAGCCGAGCTGACGGCGGTGCGGCCCGCGACGCCCCGGCCGA
CCCGCGATACTGGGCCGGCC

Downstream 100 bases:

>100_bases
CCGATCGGTGGCCGACCCGGCTCGTCAGGTCGCGATGAACAGGATCTCGTCGCGGCCGTACTCCATGCCGGGGTGCTCGG
CCGCGAGGTGCTGCTGGGTC

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAKVTLQSIADRVGVSRMTVSNAFSRPDQLSGELRERILAAADELGYVGPDPAARALARGRTGSVGLLLTDELGEAFQDA
VATQFLTSVADALTHEGLAVTLLTSGGAAGAPSDYVPARDVAMDGAIVYICDPASPDIAWLERRGLPLVSVDREPAPDAP
SVNVDDRAGARAAAEHLIELGHTRVAIITLRSTFDVAGVPTANRPASERMTGWREALEAAGIEPVVAAAAFRPRPSVEEI
ARDLLDRPDRPTAVLCFSDAFAVTTIQVAESLGLRVPEDLSVVGYDDSPLATAIRPQLTTVHQEVARKGQEAVRSLMAIM
GPDRPDPVERILLPTALVVRDSTAPPP

Sequences:

>Translated_347_residues
MAKVTLQSIADRVGVSRMTVSNAFSRPDQLSGELRERILAAADELGYVGPDPAARALARGRTGSVGLLLTDELGEAFQDA
VATQFLTSVADALTHEGLAVTLLTSGGAAGAPSDYVPARDVAMDGAIVYICDPASPDIAWLERRGLPLVSVDREPAPDAP
SVNVDDRAGARAAAEHLIELGHTRVAIITLRSTFDVAGVPTANRPASERMTGWREALEAAGIEPVVAAAAFRPRPSVEEI
ARDLLDRPDRPTAVLCFSDAFAVTTIQVAESLGLRVPEDLSVVGYDDSPLATAIRPQLTTVHQEVARKGQEAVRSLMAIM
GPDRPDPVERILLPTALVVRDSTAPPP
>Mature_346_residues
AKVTLQSIADRVGVSRMTVSNAFSRPDQLSGELRERILAAADELGYVGPDPAARALARGRTGSVGLLLTDELGEAFQDAV
ATQFLTSVADALTHEGLAVTLLTSGGAAGAPSDYVPARDVAMDGAIVYICDPASPDIAWLERRGLPLVSVDREPAPDAPS
VNVDDRAGARAAAEHLIELGHTRVAIITLRSTFDVAGVPTANRPASERMTGWREALEAAGIEPVVAAAAFRPRPSVEEIA
RDLLDRPDRPTAVLCFSDAFAVTTIQVAESLGLRVPEDLSVVGYDDSPLATAIRPQLTTVHQEVARKGQEAVRSLMAIMG
PDRPDPVERILLPTALVVRDSTAPPP

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=350, Percent_Identity=28.8571428571429, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790369, Length=347, Percent_Identity=27.9538904899135, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=28.5266457680251, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786540, Length=350, Percent_Identity=28.8571428571429, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1789202, Length=352, Percent_Identity=28.4090909090909, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789068, Length=361, Percent_Identity=26.8698060941828, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=26.7295597484277, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788474, Length=350, Percent_Identity=26.5714285714286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787580, Length=342, Percent_Identity=23.9766081871345, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787906, Length=268, Percent_Identity=26.4925373134328, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36625; Mature: 36494

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVTLQSIADRVGVSRMTVSNAFSRPDQLSGELRERILAAADELGYVGPDPAARALARG
CCCEEHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
RTGSVGLLLTDELGEAFQDAVATQFLTSVADALTHEGLAVTLLTSGGAAGAPSDYVPARD
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHH
VAMDGAIVYICDPASPDIAWLERRGLPLVSVDREPAPDAPSVNVDDRAGARAAAEHLIEL
HEECCEEEEEECCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GHTRVAIITLRSTFDVAGVPTANRPASERMTGWREALEAAGIEPVVAAAAFRPRPSVEEI
CCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
ARDLLDRPDRPTAVLCFSDAFAVTTIQVAESLGLRVPEDLSVVGYDDSPLATAIRPQLTT
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHH
VHQEVARKGQEAVRSLMAIMGPDRPDPVERILLPTALVVRDSTAPPP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure 
AKVTLQSIADRVGVSRMTVSNAFSRPDQLSGELRERILAAADELGYVGPDPAARALARG
CCEEHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
RTGSVGLLLTDELGEAFQDAVATQFLTSVADALTHEGLAVTLLTSGGAAGAPSDYVPARD
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHH
VAMDGAIVYICDPASPDIAWLERRGLPLVSVDREPAPDAPSVNVDDRAGARAAAEHLIEL
HEECCEEEEEECCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GHTRVAIITLRSTFDVAGVPTANRPASERMTGWREALEAAGIEPVVAAAAFRPRPSVEEI
CCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
ARDLLDRPDRPTAVLCFSDAFAVTTIQVAESLGLRVPEDLSVVGYDDSPLATAIRPQLTT
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHH
VHQEVARKGQEAVRSLMAIMGPDRPDPVERILLPTALVVRDSTAPPP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]