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The map label for this gene is phoR [H]

Identifier: 119714458

GI number: 119714458

Start: 202837

End: 204369

Strand: Reverse

Name: phoR [H]

Synonym: Noca_0191

Alternate gene names: 119714458

Gene position: 204369-202837 (Counterclockwise)

Preceding gene: 119714463

Following gene: 119714457

Centisome position: 4.1

GC content: 68.43

Gene sequence:

>1533_bases
GTGGCGAGGCTCCTCGCTCCGGTGAATGTGCACCTCGCGGTCGTGGTCGTGGTCCTGGCGATGCTGGGCATCTTCGGGCT
CATGTCCTCTGCCCACACGGTCGACCGGCTGACCCAGGAGACCACGCCGATCGCCGCCGACAACGCCGCCGTGCAGAGGG
ACATGCTGATCCTCCAGTCGAGCACCCATGCCTGGGTGCAGAGCGGGCAGCGGGTGGTGCTGACGCCCTACCGGATCGCC
GAGGCGCGCCTCGAGGCACGCATGGAGAGGCTCGAGGAGTACGCCGAGCCCGGATCGGACCTCGACGCTGCGGTGGACCA
GCAGGCCGAGGCGGTCGCCAGGTGGCGCGCCTACTCCGACGCGCGGATCGCCCGGCCGGGCGGCATGGAGACCTACGACT
CACGCGAGTTCATGGACGCCAAGATGCTCTTCGACCGCTTCGGACTCGCCCACGCTGCGACCACGGCCGCCTTCGATCGG
GAGATCGACGCCGCCCAACACGCCGCCCGGGTCGTGCTGACAGGTACGGTCGCGGCGATGGTGGTCGTCGGTCTCACCGG
GCTGGCCATCCTGCAGTACACCCGCCGGCGCCTCCTCCGGGCCCTCGAGCTCCCGCTCCGCAACCTCGAGAGCGTGGCGC
ACCGGCTCGCCGAGAACGACACCTCGGCTCGGGCGGAGCCGGTCGGTCCGCGCGAGGTGCAGGCGGTCACGCAGGCTCTC
AACACGCTCGCCGCCGCCCACGAACGCGCTGTCGCGGTGGAGGAGCGCCTGCGGGCCGACCAGCAGGCGCTGGACTCGGC
CAAGGACGATTTCGTCTCCAACGTGTCCCACGAGTTGCGAACGCCCTTGACCACCCTCAACGGCTACCTGGAGATGGTGC
ACGACGAGTTCGAAGGACGGCTCTCGCCACGGCACCAGAAGATGATGGACACGAGCCAGCGCAACGTCGACAGGCTGAAG
ACCCTGATCGAGGATCTGTTGACCTTGTCTCGCAGCGAGACGAAGGAACCGGCGCGTGACGTCGTCGACGGGCGAGAGCT
CGTTGCGGAGGTGGTCGACGACCTCCGGGTGACCGCGGCCCAACGAGCCATCAGGATCGCCGTGCACGACGAGCTCGACG
ACGTACCGTGGATCGTCGGTGACCGATCACAGCTCCTCCGAGCGCTGCTCAACGTCGTGGGCAACGCCGTGAAGTTCAGT
CATCAGTGCGGTCTGGTCGAAGTGGGCATGGCCCGGCAGGCGAACTGGCTGACGATCGAGATCAGCGACCACGGCCTCGG
CATCCCCGAGGATGAGATCGGACGAATCGGAAGCAGGTTCTTCCGCGGCTCCAATGCGATCAGCCAGGCGATAGGCGGCA
CCGGGCTCGGCCTTCGGATCACCCAGAGCATCATCGACGCACACGACGGCGAGATCCAGATCCGGTCCCGGCAAGGGGCC
GGTACGACGGTGACCGTTCGGCTGAGAGCCCTCTCCACCGCGACGGACGCCGAACCACCGGCTGCGTCGGCGGAGCCCTG
CCCCCAACCCTGA

Upstream 100 bases:

>100_bases
CTTGGACGAACCGGCCGATCCGCCGCCCTCGCGCCGGTCAGGATGTTCTGTCGGGCAAGTGCGGATGGACGGACGGGAGA
GCATGCAGCACCAGGGCTCG

Downstream 100 bases:

>100_bases
CCGCACCACTCGTCGGCGGCCGGCGTCACGCCTACACGCCTGGCGGCCCGAAACACACGAAACCGCAGGTCAGCGTGGAT
GCTGCCTGCGGTTCGGGTCT

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MARLLAPVNVHLAVVVVVLAMLGIFGLMSSAHTVDRLTQETTPIAADNAAVQRDMLILQSSTHAWVQSGQRVVLTPYRIA
EARLEARMERLEEYAEPGSDLDAAVDQQAEAVARWRAYSDARIARPGGMETYDSREFMDAKMLFDRFGLAHAATTAAFDR
EIDAAQHAARVVLTGTVAAMVVVGLTGLAILQYTRRRLLRALELPLRNLESVAHRLAENDTSARAEPVGPREVQAVTQAL
NTLAAAHERAVAVEERLRADQQALDSAKDDFVSNVSHELRTPLTTLNGYLEMVHDEFEGRLSPRHQKMMDTSQRNVDRLK
TLIEDLLTLSRSETKEPARDVVDGRELVAEVVDDLRVTAAQRAIRIAVHDELDDVPWIVGDRSQLLRALLNVVGNAVKFS
HQCGLVEVGMARQANWLTIEISDHGLGIPEDEIGRIGSRFFRGSNAISQAIGGTGLGLRITQSIIDAHDGEIQIRSRQGA
GTTVTVRLRALSTATDAEPPAASAEPCPQP

Sequences:

>Translated_510_residues
MARLLAPVNVHLAVVVVVLAMLGIFGLMSSAHTVDRLTQETTPIAADNAAVQRDMLILQSSTHAWVQSGQRVVLTPYRIA
EARLEARMERLEEYAEPGSDLDAAVDQQAEAVARWRAYSDARIARPGGMETYDSREFMDAKMLFDRFGLAHAATTAAFDR
EIDAAQHAARVVLTGTVAAMVVVGLTGLAILQYTRRRLLRALELPLRNLESVAHRLAENDTSARAEPVGPREVQAVTQAL
NTLAAAHERAVAVEERLRADQQALDSAKDDFVSNVSHELRTPLTTLNGYLEMVHDEFEGRLSPRHQKMMDTSQRNVDRLK
TLIEDLLTLSRSETKEPARDVVDGRELVAEVVDDLRVTAAQRAIRIAVHDELDDVPWIVGDRSQLLRALLNVVGNAVKFS
HQCGLVEVGMARQANWLTIEISDHGLGIPEDEIGRIGSRFFRGSNAISQAIGGTGLGLRITQSIIDAHDGEIQIRSRQGA
GTTVTVRLRALSTATDAEPPAASAEPCPQP
>Mature_509_residues
ARLLAPVNVHLAVVVVVLAMLGIFGLMSSAHTVDRLTQETTPIAADNAAVQRDMLILQSSTHAWVQSGQRVVLTPYRIAE
ARLEARMERLEEYAEPGSDLDAAVDQQAEAVARWRAYSDARIARPGGMETYDSREFMDAKMLFDRFGLAHAATTAAFDRE
IDAAQHAARVVLTGTVAAMVVVGLTGLAILQYTRRRLLRALELPLRNLESVAHRLAENDTSARAEPVGPREVQAVTQALN
TLAAAHERAVAVEERLRADQQALDSAKDDFVSNVSHELRTPLTTLNGYLEMVHDEFEGRLSPRHQKMMDTSQRNVDRLKT
LIEDLLTLSRSETKEPARDVVDGRELVAEVVDDLRVTAAQRAIRIAVHDELDDVPWIVGDRSQLLRALLNVVGNAVKFSH
QCGLVEVGMARQANWLTIEISDHGLGIPEDEIGRIGSRFFRGSNAISQAIGGTGLGLRITQSIIDAHDGEIQIRSRQGAG
TTVTVRLRALSTATDAEPPAASAEPCPQP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=291, Percent_Identity=28.1786941580756, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789149, Length=345, Percent_Identity=26.0869565217391, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=33.1858407079646, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790346, Length=287, Percent_Identity=28.9198606271777, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=29.2682926829268, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=27.6515151515151, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082128, Length=290, Percent_Identity=26.8965517241379, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=29.8642533936652, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=28.0701754385965, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789808, Length=287, Percent_Identity=25.4355400696864, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789403, Length=316, Percent_Identity=28.1645569620253, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=324, Percent_Identity=21.2962962962963, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=420, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=26.1044176706827, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788279, Length=298, Percent_Identity=26.510067114094, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790551, Length=322, Percent_Identity=27.3291925465839, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=24.6753246753247, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=25.3061224489796, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55769; Mature: 55638

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLLAPVNVHLAVVVVVLAMLGIFGLMSSAHTVDRLTQETTPIAADNAAVQRDMLILQS
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
STHAWVQSGQRVVLTPYRIAEARLEARMERLEEYAEPGSDLDAAVDQQAEAVARWRAYSD
CCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
ARIARPGGMETYDSREFMDAKMLFDRFGLAHAATTAAFDREIDAAQHAARVVLTGTVAAM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVGLTGLAILQYTRRRLLRALELPLRNLESVAHRLAENDTSARAEPVGPREVQAVTQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
NTLAAAHERAVAVEERLRADQQALDSAKDDFVSNVSHELRTPLTTLNGYLEMVHDEFEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
LSPRHQKMMDTSQRNVDRLKTLIEDLLTLSRSETKEPARDVVDGRELVAEVVDDLRVTAA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRAIRIAVHDELDDVPWIVGDRSQLLRALLNVVGNAVKFSHQCGLVEVGMARQANWLTIE
HHHHEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEE
ISDHGLGIPEDEIGRIGSRFFRGSNAISQAIGGTGLGLRITQSIIDAHDGEIQIRSRQGA
ECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCC
GTTVTVRLRALSTATDAEPPAASAEPCPQP
CCEEEEEEEEHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARLLAPVNVHLAVVVVVLAMLGIFGLMSSAHTVDRLTQETTPIAADNAAVQRDMLILQS
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
STHAWVQSGQRVVLTPYRIAEARLEARMERLEEYAEPGSDLDAAVDQQAEAVARWRAYSD
CCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
ARIARPGGMETYDSREFMDAKMLFDRFGLAHAATTAAFDREIDAAQHAARVVLTGTVAAM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVGLTGLAILQYTRRRLLRALELPLRNLESVAHRLAENDTSARAEPVGPREVQAVTQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
NTLAAAHERAVAVEERLRADQQALDSAKDDFVSNVSHELRTPLTTLNGYLEMVHDEFEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
LSPRHQKMMDTSQRNVDRLKTLIEDLLTLSRSETKEPARDVVDGRELVAEVVDDLRVTAA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRAIRIAVHDELDDVPWIVGDRSQLLRALLNVVGNAVKFSHQCGLVEVGMARQANWLTIE
HHHHEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEE
ISDHGLGIPEDEIGRIGSRFFRGSNAISQAIGGTGLGLRITQSIIDAHDGEIQIRSRQGA
ECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCC
GTTVTVRLRALSTATDAEPPAASAEPCPQP
CCEEEEEEEEHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]