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The map label for this gene is yafV [C]

Identifier: 119714450

GI number: 119714450

Start: 194312

End: 195097

Strand: Direct

Name: yafV [C]

Synonym: Noca_0183

Alternate gene names: 119714450

Gene position: 194312-195097 (Clockwise)

Preceding gene: 119714445

Following gene: 119714451

Centisome position: 3.9

GC content: 75.06

Gene sequence:

>786_bases
GTGCCCCCTGTCACCCCGGCTCCGCGCCTCCGGATCACCCTCGTCCAGCACGCCTCCGGCCTCGAGCCCGAGGCGAACCG
CCGGCTGTTGGGCGAGCTGACCCCGGCCGGGTCCGACCTCGTGGTCTTCCCCGAGGCGTTCGCCCGCGACTTCGGGGACG
CGGGCTCCGACGTGAGCGCGTACGCCGAGTCCCTCGACGGGCCGTTCGCGACCGAGGTGGCGCGGGTGGCCGCCGACCGC
GGGACCACGGTCGTCGCCGGCCTGTTCGAGGCGGGGGAGGATCCCACGCGGCCGTTCAACACCCTGGTGCTGCGCGGTGC
CGCGGAGGCGTCGTACCGCAAGGTCCACCTCTACGACTCCTTCGGCTACCGCGAGTCCGACCGGCTCACCGCGGGGCCGA
CCGGCCCGGCGGTGGTGGTCGAGGTCGGCGGGTTCCGGGTGGGGCTGATGACCTGCTACGACCTGCGCTTCCCCGAGCTG
GCGCGGACCCTGGTCGACGCCGGGGCGCAGCTGCTCGTCGTGCCGTCCGCCTGGGTGGCCGGGCCGCGGAAGGTCGACCA
CTGGCGCACCCTGGTGCGCGCCCGCGCCATCGAGAACACCGTGTTCGTGGCCGCCGTGGGCCAGCCCGGACCGCGCTACA
CGGGGCACTCGATGGTCGTCGACCCGCTCGGGGACGTGCTGGTCGAGGCCGGCGACGAGGCTGCGGTCGTGACCGCGACG
GTCGATCTCGAGGCGCTCGCCGCGGCCCGCCGGACCAACCCGTCCCTGGCCAACCGGCGTCTGTAA

Upstream 100 bases:

>100_bases
CGCGCGGCGCGGCCCCCGGCGAGGACGACCGCGCAGAAGCCCGTGGTGCCCGGGGGGAGGTCCATGCGATCAGTCTTCCA
CCGGTGGCACCCTGGGGGGC

Downstream 100 bases:

>100_bases
CCTCACCTCTCGTGTCCAGGTCCACCCCGCGTCGTCGAGCCGAGCGGCCGCCATCGCGCCGGGCGCGCGCCGCGGCCGCG
CTGCGCACCCGTGCCGAGCG

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPPVTPAPRLRITLVQHASGLEPEANRRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSAYAESLDGPFATEVARVAADR
GTTVVAGLFEAGEDPTRPFNTLVLRGAAEASYRKVHLYDSFGYRESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPEL
ARTLVDAGAQLLVVPSAWVAGPRKVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTAT
VDLEALAAARRTNPSLANRRL

Sequences:

>Translated_261_residues
MPPVTPAPRLRITLVQHASGLEPEANRRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSAYAESLDGPFATEVARVAADR
GTTVVAGLFEAGEDPTRPFNTLVLRGAAEASYRKVHLYDSFGYRESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPEL
ARTLVDAGAQLLVVPSAWVAGPRKVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTAT
VDLEALAAARRTNPSLANRRL
>Mature_260_residues
PPVTPAPRLRITLVQHASGLEPEANRRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSAYAESLDGPFATEVARVAADRG
TTVVAGLFEAGEDPTRPFNTLVLRGAAEASYRKVHLYDSFGYRESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPELA
RTLVDAGAQLLVVPSAWVAGPRKVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTATV
DLEALAAARRTNPSLANRRL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=246, Percent_Identity=36.1788617886179, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI297632348, Length=246, Percent_Identity=36.1788617886179, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI297632350, Length=246, Percent_Identity=36.1788617886179, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=32.5925925925926, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI297632346, Length=170, Percent_Identity=34.7058823529412, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786412, Length=263, Percent_Identity=30.7984790874525, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556280, Length=273, Percent_Identity=31.5018315018315, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323383, Length=242, Percent_Identity=30.5785123966942, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322335, Length=302, Percent_Identity=26.158940397351, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17933642, Length=236, Percent_Identity=36.0169491525424, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21355835, Length=239, Percent_Identity=30.5439330543933, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 27731; Mature: 27599

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVTPAPRLRITLVQHASGLEPEANRRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSA
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCEEEECHHHHHHHCCCCCHHHH
YAESLDGPFATEVARVAADRGTTVVAGLFEAGEDPTRPFNTLVLRGAAEASYRKVHLYDS
HHHHCCCCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCHHHEEEECCCCCCEEEEEEEEC
FGYRESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPELARTLVDAGAQLLVVPSAWVA
CCCCCCCCEECCCCCCEEEEEECCEEEEEEEEECCCCHHHHHHHHHCCCEEEEECCHHHC
GPRKVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTAT
CCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEECCHHHHHHHCCCCEEEEEEE
VDLEALAAARRTNPSLANRRL
ECHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
PPVTPAPRLRITLVQHASGLEPEANRRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSA
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCEEEECHHHHHHHCCCCCHHHH
YAESLDGPFATEVARVAADRGTTVVAGLFEAGEDPTRPFNTLVLRGAAEASYRKVHLYDS
HHHHCCCCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCHHHEEEECCCCCCEEEEEEEEC
FGYRESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPELARTLVDAGAQLLVVPSAWVA
CCCCCCCCEECCCCCCEEEEEECCEEEEEEEEECCCCHHHHHHHHHCCCEEEEECCHHHC
GPRKVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTAT
CCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEECCHHHHHHHCCCCEEEEEEE
VDLEALAAARRTNPSLANRRL
ECHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]