BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is ucpA [C]

Identifier: 119714346

GI number: 119714346

Start: 87213

End: 88028

Strand: Direct

Name: ucpA [C]

Synonym: Noca_0078

Alternate gene names: 119714346

Gene position: 87213-88028 (Clockwise)

Preceding gene: 119714345

Following gene: 119714347

Centisome position: 1.75

GC content: 72.18

Gene sequence:

>816_bases
GTGACGCCCCCGCATGAGGCGCGCGGCGGGACGCTCGAGGCCCGCACGGCGATTGTCACCGGTGGCTCGACCGGAATCGG
GATGGCGACCGCGCGTTCGCTCGCCGGCCGGGGTGCCCACGTGGTCATCGCCGGCCGAGATCGCGACCGCGGCACCAGGG
CTGCGGCGAATCTCGCCGCCGGGACGCCCGGGACGGTCACGTACGTCGAGCTGGACGTGCGGGAGGCCGAGTCGGTCGCC
GGGCTGGTCGCGACCACCGTCGAGACGTTCGGCTCGCTGGACATCCTGGTCAACAACAGCGGAGTCGAGGCGGAGGAGGG
GCCCGACGGGCCGTCCGAACCTGATTGGGACCGGATGTTCGCGACCAATGCTAAGGGCACGTGGCTGTGCTGCCGCGCCG
CGCTTCCACACCTGGAGCGTACGCACGGGGTGATCGTCAACAATGCCTCCATGGCCGGCCTCATCGGTGTTGCCGGCGGA
GCGGGCTACGCGGCGTCGAAGGCCGCGGTGGTGAGCCTCACCAAGTCCCTGGCGCTCGCCTACGCCGAGCGAGGGGTCCG
GGTCAACGCGGTGTGCGCCGGCCCGGTCGACACCCAGATGACCTACGACGAGTGGGAGCTGGTCGGCGGTCCCGAGGAGG
GACTGCGCCGTGCACTCGCGCTGAGCCCGGCGCGGCGCATCACGGCGCCGGAGGAGGTCGCCGAGCTCATCTGCTTCCTG
GCGTCCGACGACGCGGCGTCCATCACGGGGGCGGCGATACCGATCGACGGCGGCAAGACGGCGGGCCTGATGCCGACGGA
GCGGTACCGCTGGTGA

Upstream 100 bases:

>100_bases
ACCTGCTCGGATGGGACACGACCTTCCAGCAGGTCGTCCAGGGCTGCCTCATCCTCGTCGCGATCATCACCGACCGCTAC
ATCCGCCGGGTGAGAAGCAC

Downstream 100 bases:

>100_bases
CCAAGCCGGTGACGCCGAGCCACCCGTTCATTAAGATGAATATATTGGCGCAACATAATGACCGAAGGGTCAGGATGTGG
GCGCCGACCAATCGCGAAGG

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTPPHEARGGTLEARTAIVTGGSTGIGMATARSLAGRGAHVVIAGRDRDRGTRAAANLAAGTPGTVTYVELDVREAESVA
GLVATTVETFGSLDILVNNSGVEAEEGPDGPSEPDWDRMFATNAKGTWLCCRAALPHLERTHGVIVNNASMAGLIGVAGG
AGYAASKAAVVSLTKSLALAYAERGVRVNAVCAGPVDTQMTYDEWELVGGPEEGLRRALALSPARRITAPEEVAELICFL
ASDDAASITGAAIPIDGGKTAGLMPTERYRW

Sequences:

>Translated_271_residues
MTPPHEARGGTLEARTAIVTGGSTGIGMATARSLAGRGAHVVIAGRDRDRGTRAAANLAAGTPGTVTYVELDVREAESVA
GLVATTVETFGSLDILVNNSGVEAEEGPDGPSEPDWDRMFATNAKGTWLCCRAALPHLERTHGVIVNNASMAGLIGVAGG
AGYAASKAAVVSLTKSLALAYAERGVRVNAVCAGPVDTQMTYDEWELVGGPEEGLRRALALSPARRITAPEEVAELICFL
ASDDAASITGAAIPIDGGKTAGLMPTERYRW
>Mature_270_residues
TPPHEARGGTLEARTAIVTGGSTGIGMATARSLAGRGAHVVIAGRDRDRGTRAAANLAAGTPGTVTYVELDVREAESVAG
LVATTVETFGSLDILVNNSGVEAEEGPDGPSEPDWDRMFATNAKGTWLCCRAALPHLERTHGVIVNNASMAGLIGVAGGA
GYAASKAAVVSLTKSLALAYAERGVRVNAVCAGPVDTQMTYDEWELVGGPEEGLRRALALSPARRITAPEEVAELICFLA
SDDAASITGAAIPIDGGKTAGLMPTERYRW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=35.6862745098039, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=35.9683794466403, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=35.0393700787402, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=34.051724137931, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=37.9487179487179, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=33.8645418326693, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=31.0483870967742, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=31.9230769230769, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI31542939, Length=258, Percent_Identity=31.0077519379845, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.1203319502075, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=34.7150259067358, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI109715829, Length=236, Percent_Identity=29.6610169491525, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI4504505, Length=255, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=31.25, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4503301, Length=267, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=34.5549738219895, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI225579078, Length=263, Percent_Identity=28.5171102661597, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI223718074, Length=215, Percent_Identity=33.4883720930233, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI7706318, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503817, Length=228, Percent_Identity=27.1929824561404, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=28.968253968254, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40254986, Length=148, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI83715985, Length=190, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI146231950, Length=96, Percent_Identity=39.5833333333333, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=38.8235294117647, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=33.7349397590361, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=31.2, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=34.6613545816733, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=28.5140562248996, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=27.734375, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=31.7647058823529, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=27.4193548387097, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=30.3418803418803, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=28.4090909090909, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=28.2258064516129, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787526, Length=264, Percent_Identity=26.1363636363636, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=204, Percent_Identity=29.9019607843137, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=31.640625, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=32.156862745098, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=32.9545454545455, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=33.2075471698113, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=35.0393700787402, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=34.8, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=33.0855018587361, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=33.9483394833948, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=33.5793357933579, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=32.046332046332, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=35.9683794466403, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=32.5842696629214, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=35.2272727272727, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17531453, Length=279, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=33.4630350194552, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=32.8301886792453, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=31.4393939393939, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=33.0855018587361, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536651, Length=271, Percent_Identity=30.2583025830258, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=32.7137546468402, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=30.2583025830258, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=31.5018315018315, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=34.3629343629344, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=245, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=31.3492063492063, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=29.2592592592593, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=30.9644670050761, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=32.2709163346614, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=29.0155440414508, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=29.6875, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=30.3149606299213, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=264, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=29.3193717277487, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=264, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=27.5092936802974, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=28.6458333333333, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=242, Percent_Identity=28.9256198347107, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=184, Percent_Identity=29.3478260869565, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=38.28125, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=33.7254901960784, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=35.2713178294574, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=33.201581027668, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=35.15625, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=32.5396825396825, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=32.8, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=32.03125, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24644337, Length=193, Percent_Identity=33.6787564766839, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=29.4736842105263, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356301, Length=204, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24665243, Length=209, Percent_Identity=28.2296650717703, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221331218, Length=209, Percent_Identity=28.2296650717703, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24665247, Length=209, Percent_Identity=28.2296650717703, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331216, Length=209, Percent_Identity=28.2296650717703, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641388, Length=220, Percent_Identity=30.9090909090909, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921754, Length=211, Percent_Identity=28.9099526066351, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27899; Mature: 27767

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPHEARGGTLEARTAIVTGGSTGIGMATARSLAGRGAHVVIAGRDRDRGTRAAANLAA
CCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCC
GTPGTVTYVELDVREAESVAGLVATTVETFGSLDILVNNSGVEAEEGPDGPSEPDWDRMF
CCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHEE
ATNAKGTWLCCRAALPHLERTHGVIVNNASMAGLIGVAGGAGYAASKAAVVSLTKSLALA
ECCCCCCEEEHHHHCCCHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
YAERGVRVNAVCAGPVDTQMTYDEWELVGGPEEGLRRALALSPARRITAPEEVAELICFL
HHHCCCEEEEEECCCCCCCEECCCEEECCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHH
ASDDAASITGAAIPIDGGKTAGLMPTERYRW
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPPHEARGGTLEARTAIVTGGSTGIGMATARSLAGRGAHVVIAGRDRDRGTRAAANLAA
CCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCC
GTPGTVTYVELDVREAESVAGLVATTVETFGSLDILVNNSGVEAEEGPDGPSEPDWDRMF
CCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHEE
ATNAKGTWLCCRAALPHLERTHGVIVNNASMAGLIGVAGGAGYAASKAAVVSLTKSLALA
ECCCCCCEEEHHHHCCCHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
YAERGVRVNAVCAGPVDTQMTYDEWELVGGPEEGLRRALALSPARRITAPEEVAELICFL
HHHCCCEEEEEECCCCCCCEECCCEEECCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHH
ASDDAASITGAAIPIDGGKTAGLMPTERYRW
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]