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The map label for this gene is 119714347

Identifier: 119714347

GI number: 119714347

Start: 88141

End: 90204

Strand: Direct

Name: 119714347

Synonym: Noca_0079

Alternate gene names: NA

Gene position: 88141-90204 (Clockwise)

Preceding gene: 119714346

Following gene: 119714348

Centisome position: 1.77

GC content: 68.75

Gene sequence:

>2064_bases
ATGCCTGGATCGTCGTCTTCATCGGTCCGAGTCGCCGTCGATGTCGGGGGCACGTTCACCGATGTTGTGACGCTCGACTC
GGCCGACGGGGCGCTCCGGTTCGACAAGGTGCCGACGACGCCTGCCGACGCCAGCCAGGGCGTGATCAACGCGTTCGTCC
GGTCGGGCGTGGACATGCAGCGCGCTGGCTACTTCACTCACGGTACGACCCTCGGTCTGAACGCCCTCTTGACGCGGAAC
GGCGCGCGGACGGCGATCGTCACGACCGACGGCTTCCGTGACGTGTATCTCCTGGGTCGCACCGATCGGCCCGTCTCCTA
CGACTTCCGGTACAAGAAGCCCGAGAGCCTCGTCCGTCGGGACGCGATCTTCGAGGTCCCGGAGCGGATGAACTACCAGG
GCCGGGTCCTCCGCCCGTTCGACGACGTCGCCGCGCGAGCCGTCGCCGAACGGCTCAAGGACGCCGGGTACGAGTCGGTG
GCCGTGTGCTTCCTGCACGCGTACACCAACCCCGACCACGAGCTGCGGATGCGCGAGATCCTCGCCGACGTAGCGCCGGA
GATGGACGTCACGCTGTCCCACGAGCTGTCGCGCGAGTACCGGGAGTACGAGCGGACCAGCACGGCGGTCTTCGACGGCT
ACATCAAGCCGGTGGTGCGGCGCTACCTCGGCCGGCTCAAGAACGCGCTGGCCGAGAACGGCTTCGGGGGCCACTTCTTC
ATGATCCGCTCGGGGGGCGGCGCGATGACGGTCGAGAGCGCCCGCGAGGCGCCGGTGAACCTGATCCTCTCCGGCCCGGC
CGGTGGGGTGATCGGGGCGACGTCGTTCGCGCGGACGACCGGTGAGGGCAACCTCATCACCATCGACATGGGCGGTACGA
GCCTGGACGCCTCGCTCATCGTCGACGGCGAGTCCGTCCTGCGGCACGAGGCCATGTTCGAGGGCCTTCCGCTGGCCATC
CCGTCGCTGTACATCCACACGATCGGCGCCGGCGGTGGCTCGTTGGTCTGGATCGACGAGGGCGGCCACCTCCAGGTCGG
TCCGCAGAGCGCCGGGTCGTCGCCGGGTCCCGCGGCGTACAACTGGGGTGGCACGCAGGCCACGTTCACCGACGCGGCGC
TGGTGGTGGGCTATCTCGGGACCGAGACCGCGCTCGCCGGCAGTCTCGAGTTGAGGCGGGACCTCGCCGAGGATGCACTC
GTGCCGAACGCTGAGGCGTTGGGCATGTCCGTCGAGACCGTCGCCCGCGGCGTGCTGCGCATCGCGACCACCAAGATCGT
CGGAGCGGTTCGCTCGATCACCGTTGACATCGGGTACAAGCCCAACGACTTCGCCCTGCTGACCTACGGCGGTGGCGGAG
GTCTGGTCGCGGTCGATGTCGCGCACGAGCTCTCCATCCCGCGCGTCATCGTCCCGCCGGGCCCGGGAGCGTTCTCGGCG
CTCGGCATGCTGATGGCCGACGTCCAGCACGACTACTCCAGGACCCAGGTGGCTCCGTTGGACGGCATCGATCTCCAGCA
CTTGGAGTCGACGTTCGGCGAGATGGAGGGCGAAGGCGGTGCCGCGCTGCAGGACGAGGGCTTCGCGCCCGAGGATCGCA
GGTTCCAGCGGTTCATCGACGTCCGCTACCTCGGCCAGGAGCACGCCGTCTCGGTGCCGGTCGAGCGGCTGTCGGCGGAC
GAGGACATCGAGCGTCTGCGTCACGAGTTCAGCGAGATTCACGAGCGGCACTACGGCCACGCGATGTCGGATCCGATCGA
GATCGTCACGCTGCGCTCCCGTGCCGTCGGGGTCGTGGAGAGGCCCCGCCTGCCGGAGGTGCCCGAGCGGGAGGGCGACG
TCCTGACGCCGATCGCCAGCAGGGGGGTCGTGCAGCCGGACGGCTCCCGTACCCCGTACCAGGTCTACGACCGGAGCCAC
TTCCGGTTCGGTGACCGCATCGAAGGTCCGGCGATCATCGTCGAGCACACCTCGACGACGGTCATGCACACCGGCGACAC
GGCCGAGGTCGGCCGTGTCGGAGAGATCGTCATCACGCTTGCAGAGGAGACGAACCGTGGTTGA

Upstream 100 bases:

>100_bases
CGCCGAGCCACCCGTTCATTAAGATGAATATATTGGCGCAACATAATGACCGAAGGGTCAGGATGTGGGCGCCGACCAAT
CGCGAAGGAGAACAAGCCTC

Downstream 100 bases:

>100_bases
TTCCATCACTGTCGAGGTCATCCGCCACAGCCTCCTGGCGTCGGCCGATGAGATGGCGCGCAACCTGTGCCGGACGGCGT
ACAACACCGTGGTCTACGAG

Product: 5-oxoprolinase

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MPGSSSSSVRVAVDVGGTFTDVVTLDSADGALRFDKVPTTPADASQGVINAFVRSGVDMQRAGYFTHGTTLGLNALLTRN
GARTAIVTTDGFRDVYLLGRTDRPVSYDFRYKKPESLVRRDAIFEVPERMNYQGRVLRPFDDVAARAVAERLKDAGYESV
AVCFLHAYTNPDHELRMREILADVAPEMDVTLSHELSREYREYERTSTAVFDGYIKPVVRRYLGRLKNALAENGFGGHFF
MIRSGGGAMTVESAREAPVNLILSGPAGGVIGATSFARTTGEGNLITIDMGGTSLDASLIVDGESVLRHEAMFEGLPLAI
PSLYIHTIGAGGGSLVWIDEGGHLQVGPQSAGSSPGPAAYNWGGTQATFTDAALVVGYLGTETALAGSLELRRDLAEDAL
VPNAEALGMSVETVARGVLRIATTKIVGAVRSITVDIGYKPNDFALLTYGGGGGLVAVDVAHELSIPRVIVPPGPGAFSA
LGMLMADVQHDYSRTQVAPLDGIDLQHLESTFGEMEGEGGAALQDEGFAPEDRRFQRFIDVRYLGQEHAVSVPVERLSAD
EDIERLRHEFSEIHERHYGHAMSDPIEIVTLRSRAVGVVERPRLPEVPEREGDVLTPIASRGVVQPDGSRTPYQVYDRSH
FRFGDRIEGPAIIVEHTSTTVMHTGDTAEVGRVGEIVITLAEETNRG

Sequences:

>Translated_687_residues
MPGSSSSSVRVAVDVGGTFTDVVTLDSADGALRFDKVPTTPADASQGVINAFVRSGVDMQRAGYFTHGTTLGLNALLTRN
GARTAIVTTDGFRDVYLLGRTDRPVSYDFRYKKPESLVRRDAIFEVPERMNYQGRVLRPFDDVAARAVAERLKDAGYESV
AVCFLHAYTNPDHELRMREILADVAPEMDVTLSHELSREYREYERTSTAVFDGYIKPVVRRYLGRLKNALAENGFGGHFF
MIRSGGGAMTVESAREAPVNLILSGPAGGVIGATSFARTTGEGNLITIDMGGTSLDASLIVDGESVLRHEAMFEGLPLAI
PSLYIHTIGAGGGSLVWIDEGGHLQVGPQSAGSSPGPAAYNWGGTQATFTDAALVVGYLGTETALAGSLELRRDLAEDAL
VPNAEALGMSVETVARGVLRIATTKIVGAVRSITVDIGYKPNDFALLTYGGGGGLVAVDVAHELSIPRVIVPPGPGAFSA
LGMLMADVQHDYSRTQVAPLDGIDLQHLESTFGEMEGEGGAALQDEGFAPEDRRFQRFIDVRYLGQEHAVSVPVERLSAD
EDIERLRHEFSEIHERHYGHAMSDPIEIVTLRSRAVGVVERPRLPEVPEREGDVLTPIASRGVVQPDGSRTPYQVYDRSH
FRFGDRIEGPAIIVEHTSTTVMHTGDTAEVGRVGEIVITLAEETNRG
>Mature_686_residues
PGSSSSSVRVAVDVGGTFTDVVTLDSADGALRFDKVPTTPADASQGVINAFVRSGVDMQRAGYFTHGTTLGLNALLTRNG
ARTAIVTTDGFRDVYLLGRTDRPVSYDFRYKKPESLVRRDAIFEVPERMNYQGRVLRPFDDVAARAVAERLKDAGYESVA
VCFLHAYTNPDHELRMREILADVAPEMDVTLSHELSREYREYERTSTAVFDGYIKPVVRRYLGRLKNALAENGFGGHFFM
IRSGGGAMTVESAREAPVNLILSGPAGGVIGATSFARTTGEGNLITIDMGGTSLDASLIVDGESVLRHEAMFEGLPLAIP
SLYIHTIGAGGGSLVWIDEGGHLQVGPQSAGSSPGPAAYNWGGTQATFTDAALVVGYLGTETALAGSLELRRDLAEDALV
PNAEALGMSVETVARGVLRIATTKIVGAVRSITVDIGYKPNDFALLTYGGGGGLVAVDVAHELSIPRVIVPPGPGAFSAL
GMLMADVQHDYSRTQVAPLDGIDLQHLESTFGEMEGEGGAALQDEGFAPEDRRFQRFIDVRYLGQEHAVSVPVERLSADE
DIERLRHEFSEIHERHYGHAMSDPIEIVTLRSRAVGVVERPRLPEVPEREGDVLTPIASRGVVQPDGSRTPYQVYDRSHF
RFGDRIEGPAIIVEHTSTTVMHTGDTAEVGRVGEIVITLAEETNRG

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=742, Percent_Identity=30.4582210242588, Blast_Score=205, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI133901900, Length=717, Percent_Identity=25.9414225941423, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6322634, Length=738, Percent_Identity=28.7262872628726, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI45550492, Length=737, Percent_Identity=30.5291723202171, Blast_Score=249, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 73994; Mature: 73863

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGSSSSSVRVAVDVGGTFTDVVTLDSADGALRFDKVPTTPADASQGVINAFVRSGVDMQ
CCCCCCCCEEEEEEECCCEEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCHH
RAGYFTHGTTLGLNALLTRNGARTAIVTTDGFRDVYLLGRTDRPVSYDFRYKKPESLVRR
HCCCEECCCHHCCEEEEECCCCEEEEEEECCCCEEEEEECCCCCCEECCCCCCHHHHHHH
DAIFEVPERMNYQGRVLRPFDDVAARAVAERLKDAGYESVAVCFLHAYTNPDHELRMREI
HHHHHCHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHH
LADVAPEMDVTLSHELSREYREYERTSTAVFDGYIKPVVRRYLGRLKNALAENGFGGHFF
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MIRSGGGAMTVESAREAPVNLILSGPAGGVIGATSFARTTGEGNLITIDMGGTSLDASLI
EEECCCCEEEECCCCCCCEEEEEECCCCCEEECCHHHEECCCCCEEEEECCCCCCCCEEE
VDGESVLRHEAMFEGLPLAIPSLYIHTIGAGGGSLVWIDEGGHLQVGPQSAGSSPGPAAY
ECCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCCCCC
NWGGTQATFTDAALVVGYLGTETALAGSLELRRDLAEDALVPNAEALGMSVETVARGVLR
CCCCCCEEHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHH
IATTKIVGAVRSITVDIGYKPNDFALLTYGGGGGLVAVDVAHELSIPRVIVPPGPGAFSA
HHHHHHHHHEEEEEEEECCCCCCEEEEEECCCCCEEEEEEHHHCCCCEEEECCCCCHHHH
LGMLMADVQHDYSRTQVAPLDGIDLQHLESTFGEMEGEGGAALQDEGFAPEDRRFQRFID
HHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHH
VRYLGQEHAVSVPVERLSADEDIERLRHEFSEIHERHYGHAMSDPIEIVTLRSRAVGVVE
HHCCCCCCCEECCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHCCCCC
RPRLPEVPEREGDVLTPIASRGVVQPDGSRTPYQVYDRSHFRFGDRIEGPAIIVEHTSTT
CCCCCCCCCCCCCEECHHHHCCEECCCCCCCCCEECCCCCCCCCCCCCCCEEEEEECCEE
VMHTGDTAEVGRVGEIVITLAEETNRG
EEECCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
PGSSSSSVRVAVDVGGTFTDVVTLDSADGALRFDKVPTTPADASQGVINAFVRSGVDMQ
CCCCCCCEEEEEEECCCEEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCHH
RAGYFTHGTTLGLNALLTRNGARTAIVTTDGFRDVYLLGRTDRPVSYDFRYKKPESLVRR
HCCCEECCCHHCCEEEEECCCCEEEEEEECCCCEEEEEECCCCCCEECCCCCCHHHHHHH
DAIFEVPERMNYQGRVLRPFDDVAARAVAERLKDAGYESVAVCFLHAYTNPDHELRMREI
HHHHHCHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHH
LADVAPEMDVTLSHELSREYREYERTSTAVFDGYIKPVVRRYLGRLKNALAENGFGGHFF
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MIRSGGGAMTVESAREAPVNLILSGPAGGVIGATSFARTTGEGNLITIDMGGTSLDASLI
EEECCCCEEEECCCCCCCEEEEEECCCCCEEECCHHHEECCCCCEEEEECCCCCCCCEEE
VDGESVLRHEAMFEGLPLAIPSLYIHTIGAGGGSLVWIDEGGHLQVGPQSAGSSPGPAAY
ECCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCCCCC
NWGGTQATFTDAALVVGYLGTETALAGSLELRRDLAEDALVPNAEALGMSVETVARGVLR
CCCCCCEEHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHH
IATTKIVGAVRSITVDIGYKPNDFALLTYGGGGGLVAVDVAHELSIPRVIVPPGPGAFSA
HHHHHHHHHEEEEEEEECCCCCCEEEEEECCCCCEEEEEEHHHCCCCEEEECCCCCHHHH
LGMLMADVQHDYSRTQVAPLDGIDLQHLESTFGEMEGEGGAALQDEGFAPEDRRFQRFID
HHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHH
VRYLGQEHAVSVPVERLSADEDIERLRHEFSEIHERHYGHAMSDPIEIVTLRSRAVGVVE
HHCCCCCCCEECCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHCCCCC
RPRLPEVPEREGDVLTPIASRGVVQPDGSRTPYQVYDRSHFRFGDRIEGPAIIVEHTSTT
CCCCCCCCCCCCCEECHHHHCCEECCCCCCCCCEECCCCCCCCCCCCCCCEEEEEECCEE
VMHTGDTAEVGRVGEIVITLAEETNRG
EEECCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]