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The map label for this gene is dnaA [H]

Identifier: 119714273

GI number: 119714273

Start: 72

End: 1658

Strand: Direct

Name: dnaA [H]

Synonym: Noca_0001

Alternate gene names: 119714273

Gene position: 72-1658 (Clockwise)

Preceding gene: NA

Following gene: 119714274

Centisome position: 0.0

GC content: 68.75

Gene sequence:

>1587_bases
ATGGGGATCCCCGGCGACGGGCAAGACGACCGGGAGATGACTCAGAAAGCAGGAGCGGTGGACCAGAGCACCTCGGACCT
CGGCGTCGCCTGGCGCGGCGTGGTGAACGACCTGCAGCCCAACCAGCGGGCCTGGCTGCGCGCCAGCGAGCCGGTCACGC
TGCACGAGAGCACCGCGATCGTCGCGGTCCCCAACGACTTCACCCGCAACCAGCTGGAGGGCCGGCTGCGCGCCCAGCTC
GAGGACGCGCTCACCGTGCGCTTCGGCCGCGAGATCCGGATCGCCGTCACCGTCAACCCTCAGCTCGAGGACGCACCGGT
CGCCCCGGGCGACCGCACCGACTCCGCCACCGGCCGCACCGACTCGGGCACCGACCTGGCCGGCGGCGGCCATCCGGAGG
CGCCCGGACAGGCGCCGATCACCAGGCGAACCACTCAGTCTCTAAACCGATATGACGATATGTCGACAAATTCGGCTGCC
GAGCGGAGCGCGGTCGTGCCGGTGCCGCCCGCGCCCGAGCCCGACCTCGGCGCCCGCCCCAGCTCCCTGGAGACCCGGCT
CAACCCGAAGTACACCTTCGAGACCTTCGTCATCGGCTCGTCGAACCGGTTCCCGCACGCTGCTGCCGTCGCGGTCGCGG
AGGCGCCCGGCAAGGCGTACAACCCGCTCCTCGTCTACGGCGACTCCGGGCTCGGCAAGACCCACCTCCTGCACGCCATC
GGGCACTACGTGCGCTCGCTCTACACCGGCGCCAAGGTGCGCTACGTGTCCAGCGAGGAGTTCACCAACGAGTTCATCAA
CGCGATCCGCGACGACCGGCAGGACCGGTTCAAGCGCCGCTACCGAGACGTCGACGTCCTGCTGATCGACGACATCCAGT
TCCTGGAGGGCAAGACCCAGACCCAGGAGGAGTTCTTCCACACGTTCAACACCCTGCACAACGCGAACAAGCAGATCGTG
CTGACCTCCGACCGCGCGCCCAAGCGGCTCGAGGCACTCGAGGACCGGCTGCGCAACCGGTTCGAGTGGGGCCTGATCAC
CGACGTCCAGCCGCCCGACCTCGAGACCCGGATCGCGATCCTGCGCAAGAAGGCCGCCATGGACCGCCTCACCGCGCCCC
CGGACGTGCTCGAGTTCATCGCCTCGAAGATCCAGACCAACATCCGCGAGCTCGAGGGCGCGTTGATCCGGGTCACCGCG
TTCGCGAACCTCAACCGCCAGGAGGTCGACATGACCCTGGCCGAGATCGTCCTGAAGGACCTGATCCCCGAGGGCGGCGA
GCCGGAGATCACCGCGGCGCTGATCATCGCGCAGACCGCGGCGTACTTCGGCTTGTCGATCGACGAGCTCACCGGTCCCA
GCCGCGGCCGGCACCTGGTGATGGCCCGCCAGATCGCGATGTACCTGTGCCGCGAGCTCACCGACCTCTCCCTGCCCAAG
ATCGGCGCCCAGTTCGGCAACCGGGACCACACGACGGTCATGTACGCCGACCGCAAGATCAACCAGCTCCTCGCCGAGCG
CCGGGCGGTGTTCAACCAGGTCAGCGAGCTCACCAACCGGGTCAAGCTGCAGGCCCGCCAGTCCTGA

Upstream 100 bases:

>100_bases
GGACCGAGTCGGGTTCACAGCCTGTGGACAAAGTTGTGGACGCAACAAGACGCCGCGGGGCCACCGGTTCTCCGGCGGGG
CCGGCGAGACGTCCCCCACG

Downstream 100 bases:

>100_bases
CCCACCCACCGCGGCCCCACGGCGGCCCCACGGCGGCCCACAGCGGCTCCGTACCGCTCGCTACCGGTGACCTCGACGCC
TGTGGATCGATTGTGGGCCA

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MGIPGDGQDDREMTQKAGAVDQSTSDLGVAWRGVVNDLQPNQRAWLRASEPVTLHESTAIVAVPNDFTRNQLEGRLRAQL
EDALTVRFGREIRIAVTVNPQLEDAPVAPGDRTDSATGRTDSGTDLAGGGHPEAPGQAPITRRTTQSLNRYDDMSTNSAA
ERSAVVPVPPAPEPDLGARPSSLETRLNPKYTFETFVIGSSNRFPHAAAVAVAEAPGKAYNPLLVYGDSGLGKTHLLHAI
GHYVRSLYTGAKVRYVSSEEFTNEFINAIRDDRQDRFKRRYRDVDVLLIDDIQFLEGKTQTQEEFFHTFNTLHNANKQIV
LTSDRAPKRLEALEDRLRNRFEWGLITDVQPPDLETRIAILRKKAAMDRLTAPPDVLEFIASKIQTNIRELEGALIRVTA
FANLNRQEVDMTLAEIVLKDLIPEGGEPEITAALIIAQTAAYFGLSIDELTGPSRGRHLVMARQIAMYLCRELTDLSLPK
IGAQFGNRDHTTVMYADRKINQLLAERRAVFNQVSELTNRVKLQARQS

Sequences:

>Translated_528_residues
MGIPGDGQDDREMTQKAGAVDQSTSDLGVAWRGVVNDLQPNQRAWLRASEPVTLHESTAIVAVPNDFTRNQLEGRLRAQL
EDALTVRFGREIRIAVTVNPQLEDAPVAPGDRTDSATGRTDSGTDLAGGGHPEAPGQAPITRRTTQSLNRYDDMSTNSAA
ERSAVVPVPPAPEPDLGARPSSLETRLNPKYTFETFVIGSSNRFPHAAAVAVAEAPGKAYNPLLVYGDSGLGKTHLLHAI
GHYVRSLYTGAKVRYVSSEEFTNEFINAIRDDRQDRFKRRYRDVDVLLIDDIQFLEGKTQTQEEFFHTFNTLHNANKQIV
LTSDRAPKRLEALEDRLRNRFEWGLITDVQPPDLETRIAILRKKAAMDRLTAPPDVLEFIASKIQTNIRELEGALIRVTA
FANLNRQEVDMTLAEIVLKDLIPEGGEPEITAALIIAQTAAYFGLSIDELTGPSRGRHLVMARQIAMYLCRELTDLSLPK
IGAQFGNRDHTTVMYADRKINQLLAERRAVFNQVSELTNRVKLQARQS
>Mature_527_residues
GIPGDGQDDREMTQKAGAVDQSTSDLGVAWRGVVNDLQPNQRAWLRASEPVTLHESTAIVAVPNDFTRNQLEGRLRAQLE
DALTVRFGREIRIAVTVNPQLEDAPVAPGDRTDSATGRTDSGTDLAGGGHPEAPGQAPITRRTTQSLNRYDDMSTNSAAE
RSAVVPVPPAPEPDLGARPSSLETRLNPKYTFETFVIGSSNRFPHAAAVAVAEAPGKAYNPLLVYGDSGLGKTHLLHAIG
HYVRSLYTGAKVRYVSSEEFTNEFINAIRDDRQDRFKRRYRDVDVLLIDDIQFLEGKTQTQEEFFHTFNTLHNANKQIVL
TSDRAPKRLEALEDRLRNRFEWGLITDVQPPDLETRIAILRKKAAMDRLTAPPDVLEFIASKIQTNIRELEGALIRVTAF
ANLNRQEVDMTLAEIVLKDLIPEGGEPEITAALIIAQTAAYFGLSIDELTGPSRGRHLVMARQIAMYLCRELTDLSLPKI
GAQFGNRDHTTVMYADRKINQLLAERRAVFNQVSELTNRVKLQARQS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=356, Percent_Identity=46.0674157303371, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 58622; Mature: 58491

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIPGDGQDDREMTQKAGAVDQSTSDLGVAWRGVVNDLQPNQRAWLRASEPVTLHESTAI
CCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHEECCCCEEEECCEEE
VAVPNDFTRNQLEGRLRAQLEDALTVRFGREIRIAVTVNPQLEDAPVAPGDRTDSATGRT
EECCCCHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
DSGTDLAGGGHPEAPGQAPITRRTTQSLNRYDDMSTNSAAERSAVVPVPPAPEPDLGARP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCEECCCCCCCCCCCCCC
SSLETRLNPKYTFETFVIGSSNRFPHAAAVAVAEAPGKAYNPLLVYGDSGLGKTHLLHAI
CCHHHCCCCCEEEEEEEEECCCCCCCHHHEEEECCCCCCCCCEEEECCCCCCHHHHHHHH
GHYVRSLYTGAKVRYVSSEEFTNEFINAIRDDRQDRFKRRYRDVDVLLIDDIQFLEGKTQ
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCH
TQEEFFHTFNTLHNANKQIVLTSDRAPKRLEALEDRLRNRFEWGLITDVQPPDLETRIAI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHH
LRKKAAMDRLTAPPDVLEFIASKIQTNIRELEGALIRVTAFANLNRQEVDMTLAEIVLKD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LIPEGGEPEITAALIIAQTAAYFGLSIDELTGPSRGRHLVMARQIAMYLCRELTDLSLPK
HCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
IGAQFGNRDHTTVMYADRKINQLLAERRAVFNQVSELTNRVKLQARQS
HHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GIPGDGQDDREMTQKAGAVDQSTSDLGVAWRGVVNDLQPNQRAWLRASEPVTLHESTAI
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHEECCCCEEEECCEEE
VAVPNDFTRNQLEGRLRAQLEDALTVRFGREIRIAVTVNPQLEDAPVAPGDRTDSATGRT
EECCCCHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
DSGTDLAGGGHPEAPGQAPITRRTTQSLNRYDDMSTNSAAERSAVVPVPPAPEPDLGARP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCEECCCCCCCCCCCCCC
SSLETRLNPKYTFETFVIGSSNRFPHAAAVAVAEAPGKAYNPLLVYGDSGLGKTHLLHAI
CCHHHCCCCCEEEEEEEEECCCCCCCHHHEEEECCCCCCCCCEEEECCCCCCHHHHHHHH
GHYVRSLYTGAKVRYVSSEEFTNEFINAIRDDRQDRFKRRYRDVDVLLIDDIQFLEGKTQ
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCH
TQEEFFHTFNTLHNANKQIVLTSDRAPKRLEALEDRLRNRFEWGLITDVQPPDLETRIAI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHH
LRKKAAMDRLTAPPDVLEFIASKIQTNIRELEGALIRVTAFANLNRQEVDMTLAEIVLKD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LIPEGGEPEITAALIIAQTAAYFGLSIDELTGPSRGRHLVMARQIAMYLCRELTDLSLPK
HCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
IGAQFGNRDHTTVMYADRKINQLLAERRAVFNQVSELTNRVKLQARQS
HHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA