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The map label for this gene is pdxY [H]

Identifier: 119387162

GI number: 119387162

Start: 1668345

End: 1669181

Strand: Direct

Name: pdxY [H]

Synonym: Pden_4457

Alternate gene names: 119387162

Gene position: 1668345-1669181 (Clockwise)

Preceding gene: 119387161

Following gene: 119387166

Centisome position: 96.43

GC content: 70.73

Gene sequence:

>837_bases
ATGACCCGCCCGCTGGTGATCTCGATCCAGAGCCAGGTGGTCATGGGTCATGTCGGCAATTCGGCGGCGGTGTTCCCGAT
GCTGGCAGCAGGGCTGGAGGTGGCGCCGATCCCGACGGTGATCTTTTCCAATACCCCCGATTATCCGACCCTGCGCGGCC
GGCCGCTGCCGGGCGATTTCTTTGCCGAGCTGTTGCTGGGCGCCTGGGACCGCGGGTTGCCGGAACGCGCGGATTTCCTG
CTGACCGGCTATATCGGCTCGGTCGAGGTGGCACAGCTGACGGCCGATTTCGTCGCCCGCGCCAAGGCGGCGAACCCGCG
CCTGCGCTATTACTGCGATCCGGTGCTGGGCGACGAGCAGCCGGGGCTTTATGTGCCGCAGGAGATCGCCGACACCTTCC
GCGACCGGCTGCTGCCCATGGCCGACATCGCCTCGCCCAACCCGTTCGAGGTCGCCTGGCTGACCGGCCAGCCCATCGCG
GAGCTGGCCGATGTCCACCGCGCCGCGCTGGCCCTGCGCATGGCGCCCGAGGCGCAGCTGATCGTCACCGGCTGCAAGCT
GCGCGAGACGGCGCCCGGGATGCTGGAAAGCGTGATCCTGGGGCCGCAGGGGCTGACGCGGCACCCGACACCGCACCTGC
CGGTGGCGCTGGCCGGGACCGGGGATCTGTTCGCAGGGCTGATCGCCGCCGCGCTTGGCCAGGGGCGCGGCCTTGCCCAG
GCGGTCGAATTCGCGCAGGTCCAGACCTCGCGCGCGCTGCGGCGGGCGGCGGAGCTGGGCACCAAGGAGGTGGTGCTTTC
GGATCCCGAGTTCCGCGCGGCGCTGCTGGTGCCCTGA

Upstream 100 bases:

>100_bases
CCGCGCTGGACATCCTGGCCGAGGGCTGGCGGCGCTATGCCGTCCGCCGGCTGGAAAGCGGCCGGGTCGAGGACTGGTCG
AAGCGGCTGGAGGGCAGCGC

Downstream 100 bases:

>100_bases
CGCTTTCGCCCTGCGACCTGCCCGATGTTCCCCCTGGGGAAGGTTCGGCGACGGATGGAGCCCGCCTCAGTTCTTTCGCA
GCGCGTTCAGCAGCGCCGCG

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTRPLVISIQSQVVMGHVGNSAAVFPMLAAGLEVAPIPTVIFSNTPDYPTLRGRPLPGDFFAELLLGAWDRGLPERADFL
LTGYIGSVEVAQLTADFVARAKAANPRLRYYCDPVLGDEQPGLYVPQEIADTFRDRLLPMADIASPNPFEVAWLTGQPIA
ELADVHRAALALRMAPEAQLIVTGCKLRETAPGMLESVILGPQGLTRHPTPHLPVALAGTGDLFAGLIAAALGQGRGLAQ
AVEFAQVQTSRALRRAAELGTKEVVLSDPEFRAALLVP

Sequences:

>Translated_278_residues
MTRPLVISIQSQVVMGHVGNSAAVFPMLAAGLEVAPIPTVIFSNTPDYPTLRGRPLPGDFFAELLLGAWDRGLPERADFL
LTGYIGSVEVAQLTADFVARAKAANPRLRYYCDPVLGDEQPGLYVPQEIADTFRDRLLPMADIASPNPFEVAWLTGQPIA
ELADVHRAALALRMAPEAQLIVTGCKLRETAPGMLESVILGPQGLTRHPTPHLPVALAGTGDLFAGLIAAALGQGRGLAQ
AVEFAQVQTSRALRRAAELGTKEVVLSDPEFRAALLVP
>Mature_277_residues
TRPLVISIQSQVVMGHVGNSAAVFPMLAAGLEVAPIPTVIFSNTPDYPTLRGRPLPGDFFAELLLGAWDRGLPERADFLL
TGYIGSVEVAQLTADFVARAKAANPRLRYYCDPVLGDEQPGLYVPQEIADTFRDRLLPMADIASPNPFEVAWLTGQPIAE
LADVHRAALALRMAPEAQLIVTGCKLRETAPGMLESVILGPQGLTRHPTPHLPVALAGTGDLFAGLIAAALGQGRGLAQA
VEFAQVQTSRALRRAAELGTKEVVLSDPEFRAALLVP

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=244, Percent_Identity=34.0163934426229, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1788758, Length=261, Percent_Identity=31.0344827586207, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787924, Length=244, Percent_Identity=32.3770491803279, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17507759, Length=271, Percent_Identity=32.8413284132841, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17507757, Length=280, Percent_Identity=32.8571428571429, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6324354, Length=246, Percent_Identity=28.8617886178862, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6320806, Length=232, Percent_Identity=30.1724137931034, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45553007, Length=248, Percent_Identity=33.4677419354839, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 29643; Mature: 29511

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPLVISIQSQVVMGHVGNSAAVFPMLAAGLEVAPIPTVIFSNTPDYPTLRGRPLPGDF
CCCCEEEEECCEEEEEECCCCHHHHHHHHCCCEECCCCEEEECCCCCCCCCCCCCCCHHH
FAELLLGAWDRGLPERADFLLTGYIGSVEVAQLTADFVARAKAANPRLRYYCDPVLGDEQ
HHHHHHHHHCCCCCCHHCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
PGLYVPQEIADTFRDRLLPMADIASPNPFEVAWLTGQPIAELADVHRAALALRMAPEAQL
CCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEE
IVTGCKLRETAPGMLESVILGPQGLTRHPTPHLPVALAGTGDLFAGLIAAALGQGRGLAQ
EEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHH
AVEFAQVQTSRALRRAAELGTKEVVLSDPEFRAALLVP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECC
>Mature Secondary Structure 
TRPLVISIQSQVVMGHVGNSAAVFPMLAAGLEVAPIPTVIFSNTPDYPTLRGRPLPGDF
CCCEEEEECCEEEEEECCCCHHHHHHHHCCCEECCCCEEEECCCCCCCCCCCCCCCHHH
FAELLLGAWDRGLPERADFLLTGYIGSVEVAQLTADFVARAKAANPRLRYYCDPVLGDEQ
HHHHHHHHHCCCCCCHHCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
PGLYVPQEIADTFRDRLLPMADIASPNPFEVAWLTGQPIAELADVHRAALALRMAPEAQL
CCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEE
IVTGCKLRETAPGMLESVILGPQGLTRHPTPHLPVALAGTGDLFAGLIAAALGQGRGLAQ
EEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHH
AVEFAQVQTSRALRRAAELGTKEVVLSDPEFRAALLVP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA