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The map label for this gene is tldD [H]

Identifier: 119387027

GI number: 119387027

Start: 1500382

End: 1501821

Strand: Direct

Name: tldD [H]

Synonym: Pden_4322

Alternate gene names: 119387027

Gene position: 1500382-1501821 (Clockwise)

Preceding gene: 119387016

Following gene: 119387028

Centisome position: 86.72

GC content: 70.76

Gene sequence:

>1440_bases
ATGACAAGGACCGGTTCCATGACAGACGCTTCGTTTTCACCCTTCCGGACGCATCTCGATCAGGACCGCGCGCTGCGCAT
CCTGCGCGACGCCCTGGCCGGCGCGGATGACGGCGAACTTTTCCTGGAACGCTCCCGTTCCGAGGCGCTGGTCTTCGACG
ACGGCCGGCTGCGCACCGCAAGCTATGATGCCGAGCAGGGCTTCGGCCTGCGTGCCGTGCGGGACGAGGTCACCGGCTAT
GCCCATTCGACCGAGATCGACGAGGCTGCGCTGAAGAAGGCGGCCCAGACCGTGCGGCTGGCGGTCGGCGCCGGCGGCGG
CACGCTGGCCCTGCCGCCCGAGGGCGAGATCCGGCCGCTCTATGCCGCCATCGACCCGGCCGAGGACGTTCCCTTCGCCG
CCCGCGTGGCCCTCCTGCGGGAAATCGACGCCTTCGCACGCGGGCTGGACCCGCGCGTGGTGCAGGTCTCGGCCAGCATC
GCCACCTCGGTGCAGGAGGTGGCGATCCTGCGCCCCGAGGGCGGGCTTGCCACCGATATCCGGCCGATGGCACGGCTCAA
CGTCTCGGTGATCGTCGAATCGAACGCGCGGCGCGAGTCGGGCACCGCCGGCGGCGGCGGGCGCATCGGCCTTGCCGGCA
TGGTCGCCCCCGAGCACTGGCAGGGGCTGGTGCGCGAGGCGCTGCGCATCGCGCTGGTCAACCTGCGCTCGGTCCCCGCG
CCTGCCGGAGTGATGGATGTGGTGCTGGGTCCGGGCTGGCCCGGCATCCTGCTGCACGAGGCCGTGGGCCATGGGCTCGA
GGGCGATTTCAACCGCAAGGGCCATTCCGCCTTTGCCGGGCTGCTGGGCCGGCGCGTCGCGGCGCCCGGCGTGACCGTCG
TCGACGACGGCACCATTCCCGACCGGCGCGGCTCGATCTCGGTCGATGACGAGGGCACGCCGCCCGGCCGCAACGTCTTG
ATCGAGGACGGGATTCTGGTCGGCTACATGCAGGACCGGCAGAACGCCCGGCTGATGGGGGTGGCACCCACCGGCAACGG
CCGGCGGCAAAGCCACGCCCATGCCCCCATGCCGCGCATGACCAACACCTTCATGCTGGCGGGGTCCGAAGATCCGGCCT
CGATCCTTGCCGGACTCGAGGACGGCATCTATGCGGTCGGCTTCGGCGGCGGGCAGGTGGACATCACCAACGGCAAGTTC
GTGTTCTCGTGCACCGAAGCCTATCGGGTCAGGAACGGCCAGGTCGGCGACCCGATCCGCGGCGCAACGCTGATCGGCGA
CGGCGCCACCGCGCTGGAGCAGATTCGCGCCATCGGAAACGACCTGTCGCTGGACCCGGGAATCGGCAATTGCGGCAAGC
AGGGCCAATGGGTTCCGGTCGGCGTCGGCCTGCCCACGCTGCGCATCGGCGGGCTGACCATCGGCGGGTCTGCGGCCTGA

Upstream 100 bases:

>100_bases
GAGGCCGCCGGCATTCGGTCCTGCACCAGAACCATATCTTACCCCGGCGGGCAAGCCATACCTATCGACTTCTTGTCAAA
AAAGCCCTAGGCGGGGCTTC

Downstream 100 bases:

>100_bases
ATCGCTTGTATTCCAATATCTTGAAGGATTCCTTGGGCCGCTAACCCATTCTTAACCATTGCCATGCCATGACTCGGCCT
GCGGATGAGGCAAAGGCATG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTRTGSMTDASFSPFRTHLDQDRALRILRDALAGADDGELFLERSRSEALVFDDGRLRTASYDAEQGFGLRAVRDEVTGY
AHSTEIDEAALKKAAQTVRLAVGAGGGTLALPPEGEIRPLYAAIDPAEDVPFAARVALLREIDAFARGLDPRVVQVSASI
ATSVQEVAILRPEGGLATDIRPMARLNVSVIVESNARRESGTAGGGGRIGLAGMVAPEHWQGLVREALRIALVNLRSVPA
PAGVMDVVLGPGWPGILLHEAVGHGLEGDFNRKGHSAFAGLLGRRVAAPGVTVVDDGTIPDRRGSISVDDEGTPPGRNVL
IEDGILVGYMQDRQNARLMGVAPTGNGRRQSHAHAPMPRMTNTFMLAGSEDPASILAGLEDGIYAVGFGGGQVDITNGKF
VFSCTEAYRVRNGQVGDPIRGATLIGDGATALEQIRAIGNDLSLDPGIGNCGKQGQWVPVGVGLPTLRIGGLTIGGSAA

Sequences:

>Translated_479_residues
MTRTGSMTDASFSPFRTHLDQDRALRILRDALAGADDGELFLERSRSEALVFDDGRLRTASYDAEQGFGLRAVRDEVTGY
AHSTEIDEAALKKAAQTVRLAVGAGGGTLALPPEGEIRPLYAAIDPAEDVPFAARVALLREIDAFARGLDPRVVQVSASI
ATSVQEVAILRPEGGLATDIRPMARLNVSVIVESNARRESGTAGGGGRIGLAGMVAPEHWQGLVREALRIALVNLRSVPA
PAGVMDVVLGPGWPGILLHEAVGHGLEGDFNRKGHSAFAGLLGRRVAAPGVTVVDDGTIPDRRGSISVDDEGTPPGRNVL
IEDGILVGYMQDRQNARLMGVAPTGNGRRQSHAHAPMPRMTNTFMLAGSEDPASILAGLEDGIYAVGFGGGQVDITNGKF
VFSCTEAYRVRNGQVGDPIRGATLIGDGATALEQIRAIGNDLSLDPGIGNCGKQGQWVPVGVGLPTLRIGGLTIGGSAA
>Mature_478_residues
TRTGSMTDASFSPFRTHLDQDRALRILRDALAGADDGELFLERSRSEALVFDDGRLRTASYDAEQGFGLRAVRDEVTGYA
HSTEIDEAALKKAAQTVRLAVGAGGGTLALPPEGEIRPLYAAIDPAEDVPFAARVALLREIDAFARGLDPRVVQVSASIA
TSVQEVAILRPEGGLATDIRPMARLNVSVIVESNARRESGTAGGGGRIGLAGMVAPEHWQGLVREALRIALVNLRSVPAP
AGVMDVVLGPGWPGILLHEAVGHGLEGDFNRKGHSAFAGLLGRRVAAPGVTVVDDGTIPDRRGSISVDDEGTPPGRNVLI
EDGILVGYMQDRQNARLMGVAPTGNGRRQSHAHAPMPRMTNTFMLAGSEDPASILAGLEDGIYAVGFGGGQVDITNGKFV
FSCTEAYRVRNGQVGDPIRGATLIGDGATALEQIRAIGNDLSLDPGIGNCGKQGQWVPVGVGLPTLRIGGLTIGGSAA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=451, Percent_Identity=52.549889135255, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50046; Mature: 49915

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTGSMTDASFSPFRTHLDQDRALRILRDALAGADDGELFLERSRSEALVFDDGRLRTA
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECCCEEEE
SYDAEQGFGLRAVRDEVTGYAHSTEIDEAALKKAAQTVRLAVGAGGGTLALPPEGEIRPL
CCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEEECCCCEEECCCCCCCEEE
YAAIDPAEDVPFAARVALLREIDAFARGLDPRVVQVSASIATSVQEVAILRPEGGLATDI
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHEEEECCCCCCCCCC
RPMARLNVSVIVESNARRESGTAGGGGRIGLAGMVAPEHWQGLVREALRIALVNLRSVPA
CHHHHCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
PAGVMDVVLGPGWPGILLHEAVGHGLEGDFNRKGHSAFAGLLGRRVAAPGVTVVDDGTIP
CCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
DRRGSISVDDEGTPPGRNVLIEDGILVGYMQDRQNARLMGVAPTGNGRRQSHAHAPMPRM
CCCCCEEECCCCCCCCCEEEEECCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCC
TNTFMLAGSEDPASILAGLEDGIYAVGFGGGQVDITNGKFVFSCTEAYRVRNGQVGDPIR
CCEEEEECCCCHHHHHHHCCCCEEEEEECCCEEEEECCEEEEEEHHHHHCCCCCCCCCCC
GATLIGDGATALEQIRAIGNDLSLDPGIGNCGKQGQWVPVGVGLPTLRIGGLTIGGSAA
CCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCEEECCCCC
>Mature Secondary Structure 
TRTGSMTDASFSPFRTHLDQDRALRILRDALAGADDGELFLERSRSEALVFDDGRLRTA
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECCCEEEE
SYDAEQGFGLRAVRDEVTGYAHSTEIDEAALKKAAQTVRLAVGAGGGTLALPPEGEIRPL
CCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEEECCCCEEECCCCCCCEEE
YAAIDPAEDVPFAARVALLREIDAFARGLDPRVVQVSASIATSVQEVAILRPEGGLATDI
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHEEEECCCCCCCCCC
RPMARLNVSVIVESNARRESGTAGGGGRIGLAGMVAPEHWQGLVREALRIALVNLRSVPA
CHHHHCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
PAGVMDVVLGPGWPGILLHEAVGHGLEGDFNRKGHSAFAGLLGRRVAAPGVTVVDDGTIP
CCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
DRRGSISVDDEGTPPGRNVLIEDGILVGYMQDRQNARLMGVAPTGNGRRQSHAHAPMPRM
CCCCCEEECCCCCCCCCEEEEECCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCC
TNTFMLAGSEDPASILAGLEDGIYAVGFGGGQVDITNGKFVFSCTEAYRVRNGQVGDPIR
CCEEEEECCCCHHHHHHHCCCCEEEEEECCCEEEEECCEEEEEEHHHHHCCCCCCCCCCC
GATLIGDGATALEQIRAIGNDLSLDPGIGNCGKQGQWVPVGVGLPTLRIGGLTIGGSAA
CCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]