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The map label for this gene is nac [H]

Identifier: 119386823

GI number: 119386823

Start: 1270064

End: 1271038

Strand: Direct

Name: nac [H]

Synonym: Pden_4118

Alternate gene names: 119386823

Gene position: 1270064-1271038 (Clockwise)

Preceding gene: 119386822

Following gene: 119386824

Centisome position: 73.41

GC content: 67.59

Gene sequence:

>975_bases
ATGATGGACATCCGCCAGCTTCGCTATTTCGTGGCCATCGTCGAACACGGCTCGTTCTCGCGTGCCGCCGAATTCCTGCA
TGTCGCCCAGCCGGCGCTGTCGCTGCATGTGCGCAACATGGAGGCCGGGCTGGACACGCCGCTGCTGTTTCGCAGCCCGC
GCGGGGTCGAGCCGACCGAGGCGGGGGCGATCCTGCTGCGCCATGCCCGGACAATTCTCGACCAGCTTGCCGTCGCCGAG
GAGGAGATCCGCGGCCATGAGAACGATCCCGCGGGCGAGGTCCGTCTGGGCCTTCCCGGCACGATCGGCGAGATCCTGGC
CGTGCCGCTGATCACCGCCGTTCACTTGCGCTACCCCAAGATCAAGCTGCGCATCGCCGAGGCGATGAGCGGCTTCGTGC
TGGAATGGATGCGAGAGGGCCGGATCGACCTTGCCGTGCTCTACGGTCAGGCGGCAGAGCACGGCATCTCGACCGAGGCC
CTGCTGGAGGAGACGCTGCGGTTCTTCGGCCCTGCCCACCTGGCCGCAAGGGATGACCTGCCCGCACCCGGCAAGCCCAT
CCCCATGGCCGAAGTGACACGCAAGCCGCTGATCCTGCCCGGCGAAGGGCATGGATTGCGGGAATTGCTCAAGCGCCAGG
CGCTTTCGGCCGCGCAGGAGCTGAACACCGTGATGGATGTCGATTCGTACAGCAACATCAAGCTGCTGGTTGGGGAGGGG
CTGGGGTATTCGGTGCTGCCCGAGAACGCCATTGCCCCCGAGATCACCGAGGGCCGGTTGCTGAGCTGGCCCATCGGCGA
GCCGGCGATCCGCCGGACCGTGCATCTGGCGCATTCCGCGGACCGGCCGATGACGAATGCGGTCACCGTCGTGCGGGCGC
TTGCGCGCGAGATCCTGCGCGACCTGGTCCGCAATCACCGCTGGATCGGTGCCACGGTCCTTGCCGCCGAGGAACCCGCC
AAGCCGCCCCCCTGA

Upstream 100 bases:

>100_bases
CATGGCGCGACAACATCCGCGTCCGGGACGGCAAGGCGGTGCTCGTCCAGCCCCTGGTCTGCTGGACGCTGGCGCGGGCC
GAGGATTCCGGGGGGCGACC

Downstream 100 bases:

>100_bases
GGAACAGCCATGCCCGCGATCACCGAAGGCCATGTCATCGACAGCGTGGCCGACGCCCTGCAGTTCATATCGTATTACCA
TCCGCGCGATTTCATCCGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MMDIRQLRYFVAIVEHGSFSRAAEFLHVAQPALSLHVRNMEAGLDTPLLFRSPRGVEPTEAGAILLRHARTILDQLAVAE
EEIRGHENDPAGEVRLGLPGTIGEILAVPLITAVHLRYPKIKLRIAEAMSGFVLEWMREGRIDLAVLYGQAAEHGISTEA
LLEETLRFFGPAHLAARDDLPAPGKPIPMAEVTRKPLILPGEGHGLRELLKRQALSAAQELNTVMDVDSYSNIKLLVGEG
LGYSVLPENAIAPEITEGRLLSWPIGEPAIRRTVHLAHSADRPMTNAVTVVRALAREILRDLVRNHRWIGATVLAAEEPA
KPPP

Sequences:

>Translated_324_residues
MMDIRQLRYFVAIVEHGSFSRAAEFLHVAQPALSLHVRNMEAGLDTPLLFRSPRGVEPTEAGAILLRHARTILDQLAVAE
EEIRGHENDPAGEVRLGLPGTIGEILAVPLITAVHLRYPKIKLRIAEAMSGFVLEWMREGRIDLAVLYGQAAEHGISTEA
LLEETLRFFGPAHLAARDDLPAPGKPIPMAEVTRKPLILPGEGHGLRELLKRQALSAAQELNTVMDVDSYSNIKLLVGEG
LGYSVLPENAIAPEITEGRLLSWPIGEPAIRRTVHLAHSADRPMTNAVTVVRALAREILRDLVRNHRWIGATVLAAEEPA
KPPP
>Mature_324_residues
MMDIRQLRYFVAIVEHGSFSRAAEFLHVAQPALSLHVRNMEAGLDTPLLFRSPRGVEPTEAGAILLRHARTILDQLAVAE
EEIRGHENDPAGEVRLGLPGTIGEILAVPLITAVHLRYPKIKLRIAEAMSGFVLEWMREGRIDLAVLYGQAAEHGISTEA
LLEETLRFFGPAHLAARDDLPAPGKPIPMAEVTRKPLILPGEGHGLRELLKRQALSAAQELNTVMDVDSYSNIKLLVGEG
LGYSVLPENAIAPEITEGRLLSWPIGEPAIRRTVHLAHSADRPMTNAVTVVRALAREILRDLVRNHRWIGATVLAAEEPA
KPPP

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=254, Percent_Identity=33.8582677165354, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1790399, Length=286, Percent_Identity=31.4685314685315, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787601, Length=175, Percent_Identity=33.1428571428571, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=26.7489711934156, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI145693105, Length=302, Percent_Identity=28.476821192053, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788748, Length=315, Percent_Identity=27.3015873015873, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=25.7839721254355, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787879, Length=278, Percent_Identity=30.5755395683453, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786401, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082132, Length=290, Percent_Identity=23.448275862069, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789506, Length=299, Percent_Identity=24.0802675585284, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788887, Length=155, Percent_Identity=32.9032258064516, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367136, Length=103, Percent_Identity=40.7766990291262, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081904, Length=299, Percent_Identity=24.7491638795987, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=267, Percent_Identity=23.2209737827715, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789639, Length=129, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787949, Length=135, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787530, Length=260, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35523; Mature: 35523

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDIRQLRYFVAIVEHGSFSRAAEFLHVAQPALSLHVRNMEAGLDTPLLFRSPRGVEPTE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHHHHCCCCCCEEECCCCCCCCCH
AGAILLRHARTILDQLAVAEEEIRGHENDPAGEVRLGLPGTIGEILAVPLITAVHLRYPK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCH
IKLRIAEAMSGFVLEWMREGRIDLAVLYGQAAEHGISTEALLEETLRFFGPAHLAARDDL
HEEHHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHCCHHHCCCCCC
PAPGKPIPMAEVTRKPLILPGEGHGLRELLKRQALSAAQELNTVMDVDSYSNIKLLVGEG
CCCCCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
LGYSVLPENAIAPEITEGRLLSWPIGEPAIRRTVHLAHSADRPMTNAVTVVRALAREILR
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DLVRNHRWIGATVLAAEEPAKPPP
HHHHCCCEECEEEEECCCCCCCCC
>Mature Secondary Structure
MMDIRQLRYFVAIVEHGSFSRAAEFLHVAQPALSLHVRNMEAGLDTPLLFRSPRGVEPTE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHHHHCCCCCCEEECCCCCCCCCH
AGAILLRHARTILDQLAVAEEEIRGHENDPAGEVRLGLPGTIGEILAVPLITAVHLRYPK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCH
IKLRIAEAMSGFVLEWMREGRIDLAVLYGQAAEHGISTEALLEETLRFFGPAHLAARDDL
HEEHHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHCCHHHCCCCCC
PAPGKPIPMAEVTRKPLILPGEGHGLRELLKRQALSAAQELNTVMDVDSYSNIKLLVGEG
CCCCCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
LGYSVLPENAIAPEITEGRLLSWPIGEPAIRRTVHLAHSADRPMTNAVTVVRALAREILR
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DLVRNHRWIGATVLAAEEPAKPPP
HHHHCCCEECEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]