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The map label for this gene is murI

Identifier: 119386680

GI number: 119386680

Start: 1112959

End: 1113771

Strand: Direct

Name: murI

Synonym: Pden_3973

Alternate gene names: 119386680

Gene position: 1112959-1113771 (Clockwise)

Preceding gene: 119386677

Following gene: 119386681

Centisome position: 64.33

GC content: 67.04

Gene sequence:

>813_bases
ATGGCGGTGGGCGTATTCGATTCGGGTCTGGGCGGACTGACGGTTCTGTCTGCGATCGCCGCGCGCATGCCCGACCTGCC
CCTGGTCTATCTGGGCGACAATGCCCATACCCCCTACGGCGTGCGCGACGCCGACGACATCTTCGATCTGACCTGCGCCG
GGGTCGAGCGGCTTTGGGCCGAGGGTTGCGATCTGGTGATCCTGGCCTGCAACACCGCCTCGGCCGCCGCGCTCAAGCGC
ATGCAGGAAACCTGGCTGCCCAAGGACAAGCGCGTTCTGGGGGTCTTCGTGCCAATGATCGAGGCGCTGACCGAACGGCG
CTGGGGCGACAATTCGCCGCCGCGCGAGGTGGCAGTAAAGCATGTGGCGCTGTTCGCCACGCCCGCGACCGTCGCCAGCC
GCGCCTTCCAGCGGGAACTGGCCTTTCGCGCCATCGGCGTCGATGTCGAGGCCCAGCCTTGCGGCGGCGTCGTCGATGCC
ATCGAGATGGGCGACGAGATCCTGGCCGAGGCGCTGGTGACATCCCATGTCGAGGCGCTGCTGCGCCGCATGCCGCATCC
CGAAGCGGCGATCCTGGGCTGCACCCATTACCCGCTGGTGCAGGCCGCCTTCCAGAAGGCGCTGGGGCCGCAGGTCACGG
TCTATTCCCAGCCCAACCTCGTGGCGGAAAGCCTTGAGGACTATCTTGGGCGCCATCCCGAAATGCTGGGCGCGGGCAAT
GTCTCGCGCTTCCTGACCACCGGCGATCCTGAGCGGGTCTCGGGCAAGGCCACTCAATTCCTCCGCCATCCGATCAGGTT
CGAAAGCGCCTGA

Upstream 100 bases:

>100_bases
CGCTGCAACGCGTCCGATCCACGTCTGGCCAGGTGACATAAATCATGGCGTTCCGGTCCGGTGCATCCTAAAAAGACCTG
TCGCGAGCAGGAGGCAAGTC

Downstream 100 bases:

>100_bases
AGCAGGAAAGCTTGCACCATGAAGTCTTTGAAGAAAAAGCGCCGTATCCAGATCCTCGTCGCCGCTGCCGTGGCCCTTGT
CCTGGCCGTCGGGCTGATCG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAVGVFDSGLGGLTVLSAIAARMPDLPLVYLGDNAHTPYGVRDADDIFDLTCAGVERLWAEGCDLVILACNTASAAALKR
MQETWLPKDKRVLGVFVPMIEALTERRWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDA
IEMGDEILAEALVTSHVEALLRRMPHPEAAILGCTHYPLVQAAFQKALGPQVTVYSQPNLVAESLEDYLGRHPEMLGAGN
VSRFLTTGDPERVSGKATQFLRHPIRFESA

Sequences:

>Translated_270_residues
MAVGVFDSGLGGLTVLSAIAARMPDLPLVYLGDNAHTPYGVRDADDIFDLTCAGVERLWAEGCDLVILACNTASAAALKR
MQETWLPKDKRVLGVFVPMIEALTERRWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDA
IEMGDEILAEALVTSHVEALLRRMPHPEAAILGCTHYPLVQAAFQKALGPQVTVYSQPNLVAESLEDYLGRHPEMLGAGN
VSRFLTTGDPERVSGKATQFLRHPIRFESA
>Mature_269_residues
AVGVFDSGLGGLTVLSAIAARMPDLPLVYLGDNAHTPYGVRDADDIFDLTCAGVERLWAEGCDLVILACNTASAAALKRM
QETWLPKDKRVLGVFVPMIEALTERRWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDAI
EMGDEILAEALVTSHVEALLRRMPHPEAAILGCTHYPLVQAAFQKALGPQVTVYSQPNLVAESLEDYLGRHPEMLGAGNV
SRFLTTGDPERVSGKATQFLRHPIRFESA

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=201, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_PARDP (A1B945)

Other databases:

- EMBL:   CP000490
- RefSeq:   YP_917735.1
- ProteinModelPortal:   A1B945
- SMR:   A1B945
- STRING:   A1B945
- GeneID:   4582524
- GenomeReviews:   CP000490_GR
- KEGG:   pde:Pden_3973
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   CLSK933660
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29144; Mature: 29013

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGVFDSGLGGLTVLSAIAARMPDLPLVYLGDNAHTPYGVRDADDIFDLTCAGVERLWA
CEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EGCDLVILACNTASAAALKRMQETWLPKDKRVLGVFVPMIEALTERRWGDNSPPREVAVK
CCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
HVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDAIEMGDEILAEALVTSHVEAL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRMPHPEAAILGCTHYPLVQAAFQKALGPQVTVYSQPNLVAESLEDYLGRHPEMLGAGN
HHHCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHCCCC
VSRFLTTGDPERVSGKATQFLRHPIRFESA
HHHHEECCCHHHHCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AVGVFDSGLGGLTVLSAIAARMPDLPLVYLGDNAHTPYGVRDADDIFDLTCAGVERLWA
EECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EGCDLVILACNTASAAALKRMQETWLPKDKRVLGVFVPMIEALTERRWGDNSPPREVAVK
CCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
HVALFATPATVASRAFQRELAFRAIGVDVEAQPCGGVVDAIEMGDEILAEALVTSHVEAL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRMPHPEAAILGCTHYPLVQAAFQKALGPQVTVYSQPNLVAESLEDYLGRHPEMLGAGN
HHHCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHCCCC
VSRFLTTGDPERVSGKATQFLRHPIRFESA
HHHHEECCCHHHHCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA