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The map label for this gene is yccK [H]

Identifier: 119385966

GI number: 119385966

Start: 409473

End: 410462

Strand: Direct

Name: yccK [H]

Synonym: Pden_3244

Alternate gene names: 119385966

Gene position: 409473-410462 (Clockwise)

Preceding gene: 119385965

Following gene: 119385967

Centisome position: 23.67

GC content: 65.86

Gene sequence:

>990_bases
ATGAAAAGCAGAAATCTAGGAAATCTTGAGGTCTCGGCCCTCGGCCTCGGCTGCATGGGGATGACGGGCGTTTACGGTCC
GGGCGTCGAAAAGGCCGACATGATCCGGCTTATCCACGACGCGCATGACCGCGGCGTGACCTTCTTCGACACGGCCGAAG
CCTATGGCCCCTTCGCCAACGAGGAATTGCTTGGCGAGGCGCTTCAGCCGATCCGCGACAAGGTGGTGATCGCCACCAAG
TTCGGCTTCGACATCGACCTGGAGACCGGCGCCCGCAACGGCGGCACCAACAGCCGTCCCGAACGCATCAAGGCGGTGGC
GGACGCGGCGCTCAGGCGGCTGCGCACCGACCGCATCGACCTGTTCTACCAGCACCGCGTCGATCCGAACGTGCCGATCG
AGGATGTCGCCGGAGCGGTGAAAGACCTGATCGCCGCGGGCAAAGTCAAGCATTTCGGCCTGTCGGAAGCCGGGGTCGGC
ACCATCCGTCGCGCCCATGCCGTCCAGCCCGTGACTGCGGTGCAGAGCGAGTATTCGCTGTTCTGGCGTGGGCCGGAAGT
GGAGCTTCTGCCGGTGCTGGAGGAACTCGGTATCGGCTTCGTGCCCTTCAGCCCGCTGGGCGCGGGTTTCCTGACCGGCA
AGATTGACGAGACCACCACCTTCGAGCAGGGCGATTTCCGCAACCTTGTTCCGCGCTTCTCGCCCGAGGCCCGCAAGGCC
AACATGGCGCTGGTCGGCGTGGTCAAGAGCGTGGCGGATCGCAAGGGCGCGACGCCCGCCCAGGTCACGCTCGCCTGGCT
GCTGGCACAGAAGCCCTGGATCGTGCCGATCCCCGGCACCACCAAGCTGCACCGTCTTGAGGAGAACCTGGGCGCGGTCG
AGCTGGAGCTGACGGCCACCGATCTCGCGGAGATCGACGCCGAGGCGTCGAAGATCGAAGTCCAGGGCGAGCGCCTGCCC
GAGGCCGTGCTGAAGATGACCGGCCTGTGA

Upstream 100 bases:

>100_bases
ATGGCCGTCGCGGCGATCGAGCTGCGCGGCCAACGTCTCCCCGACGCCGTTCTGGCCTTCTCGAATGTCGAGGCTCCGGC
AAGGAATTAAGGAAGTAGAC

Downstream 100 bases:

>100_bases
GCGCGTTGAAATTGAAAGGATCAATCAGATGAACGACACCAAGATCAGCGACTTCACCCCTGTTTATCGGGGCGCGATCA
CCGCGAATGAATCGGGCAAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKSRNLGNLEVSALGLGCMGMTGVYGPGVEKADMIRLIHDAHDRGVTFFDTAEAYGPFANEELLGEALQPIRDKVVIATK
FGFDIDLETGARNGGTNSRPERIKAVADAALRRLRTDRIDLFYQHRVDPNVPIEDVAGAVKDLIAAGKVKHFGLSEAGVG
TIRRAHAVQPVTAVQSEYSLFWRGPEVELLPVLEELGIGFVPFSPLGAGFLTGKIDETTTFEQGDFRNLVPRFSPEARKA
NMALVGVVKSVADRKGATPAQVTLAWLLAQKPWIVPIPGTTKLHRLEENLGAVELELTATDLAEIDAEASKIEVQGERLP
EAVLKMTGL

Sequences:

>Translated_329_residues
MKSRNLGNLEVSALGLGCMGMTGVYGPGVEKADMIRLIHDAHDRGVTFFDTAEAYGPFANEELLGEALQPIRDKVVIATK
FGFDIDLETGARNGGTNSRPERIKAVADAALRRLRTDRIDLFYQHRVDPNVPIEDVAGAVKDLIAAGKVKHFGLSEAGVG
TIRRAHAVQPVTAVQSEYSLFWRGPEVELLPVLEELGIGFVPFSPLGAGFLTGKIDETTTFEQGDFRNLVPRFSPEARKA
NMALVGVVKSVADRKGATPAQVTLAWLLAQKPWIVPIPGTTKLHRLEENLGAVELELTATDLAEIDAEASKIEVQGERLP
EAVLKMTGL
>Mature_329_residues
MKSRNLGNLEVSALGLGCMGMTGVYGPGVEKADMIRLIHDAHDRGVTFFDTAEAYGPFANEELLGEALQPIRDKVVIATK
FGFDIDLETGARNGGTNSRPERIKAVADAALRRLRTDRIDLFYQHRVDPNVPIEDVAGAVKDLIAAGKVKHFGLSEAGVG
TIRRAHAVQPVTAVQSEYSLFWRGPEVELLPVLEELGIGFVPFSPLGAGFLTGKIDETTTFEQGDFRNLVPRFSPEARKA
NMALVGVVKSVADRKGATPAQVTLAWLLAQKPWIVPIPGTTKLHRLEENLGAVELELTATDLAEIDAEASKIEVQGERLP
EAVLKMTGL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=327, Percent_Identity=30.8868501529052, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436969, Length=327, Percent_Identity=29.0519877675841, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=29.0123456790123, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436966, Length=327, Percent_Identity=30.5810397553517, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=30.8868501529052, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436962, Length=328, Percent_Identity=31.0975609756098, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI223718702, Length=282, Percent_Identity=28.7234042553192, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI41152114, Length=224, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=28.1138790035587, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=32.7102803738318, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789375, Length=297, Percent_Identity=30.6397306397306, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787674, Length=315, Percent_Identity=30.4761904761905, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=28.8888888888889, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789199, Length=339, Percent_Identity=28.6135693215339, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788081, Length=265, Percent_Identity=26.0377358490566, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI48994888, Length=299, Percent_Identity=26.4214046822742, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=26.865671641791, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=318, Percent_Identity=25.7861635220126, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325384, Length=321, Percent_Identity=27.7258566978193, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=292, Percent_Identity=24.6575342465753, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=317, Percent_Identity=24.2902208201893, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=24.8031496062992, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24640980, Length=341, Percent_Identity=24.3401759530792, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549126, Length=341, Percent_Identity=24.0469208211144, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35615; Mature: 35615

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRNLGNLEVSALGLGCMGMTGVYGPGVEKADMIRLIHDAHDRGVTFFDTAEAYGPFAN
CCCCCCCCEEEEEEEECHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHCCCCC
EELLGEALQPIRDKVVIATKFGFDIDLETGARNGGTNSRPERIKAVADAALRRLRTDRID
HHHHHHHHHHHHHCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFYQHRVDPNVPIEDVAGAVKDLIAAGKVKHFGLSEAGVGTIRRAHAVQPVTAVQSEYSL
EEEEECCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHCCCHHHHHHCCEE
FWRGPEVELLPVLEELGIGFVPFSPLGAGFLTGKIDETTTFEQGDFRNLVPRFSPEARKA
EECCCCCEEHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHCCCCCCCCHHHC
NMALVGVVKSVADRKGATPAQVTLAWLLAQKPWIVPIPGTTKLHRLEENLGAVELELTAT
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEEEEEHH
DLAEIDAEASKIEVQGERLPEAVLKMTGL
HHHHHCCCCCEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MKSRNLGNLEVSALGLGCMGMTGVYGPGVEKADMIRLIHDAHDRGVTFFDTAEAYGPFAN
CCCCCCCCEEEEEEEECHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHCCCCC
EELLGEALQPIRDKVVIATKFGFDIDLETGARNGGTNSRPERIKAVADAALRRLRTDRID
HHHHHHHHHHHHHCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFYQHRVDPNVPIEDVAGAVKDLIAAGKVKHFGLSEAGVGTIRRAHAVQPVTAVQSEYSL
EEEEECCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHCCCHHHHHHCCEE
FWRGPEVELLPVLEELGIGFVPFSPLGAGFLTGKIDETTTFEQGDFRNLVPRFSPEARKA
EECCCCCEEHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHCCCCCCCCHHHC
NMALVGVVKSVADRKGATPAQVTLAWLLAQKPWIVPIPGTTKLHRLEENLGAVELELTAT
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEEEEEHH
DLAEIDAEASKIEVQGERLPEAVLKMTGL
HHHHHCCCCCEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]