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The map label for this gene is yccK [H]

Identifier: 119385965

GI number: 119385965

Start: 408296

End: 409462

Strand: Direct

Name: yccK [H]

Synonym: Pden_3243

Alternate gene names: 119385965

Gene position: 408296-409462 (Clockwise)

Preceding gene: 119385964

Following gene: 119385966

Centisome position: 23.6

GC content: 66.07

Gene sequence:

>1167_bases
ATGACAAACGAACAGAAACTGAAGATCGGGCGGCGGGGTTTCCTGGGTGCGGCGGGCGGCCTGGCCGCGGCGCCGCTGCT
CGTCTCGACCGGCTCCGGGGTCTCCGCACAGGAAGCCGCGCAAGGGACGGGCATCTATGCCACCGCCCCCTCGTTGAGTG
GTCGGCGGATGCTGGGAACGCTGGAGGTGTCGAGCATCGGCCTTGGCGTTCAGAACATGCACCGCACCTATCAGACGACG
ATCCCGTCGCGGCCAGAGATGATCAACATCATCCGCACCGCCCATGACCGTGGCGTCACGTTCTTCGATACAGCCGAAGC
CTATGGCCCGCATGAATGCGAGCGGATTCTGGGCGAAGCCGTTGAGCCGTTCCGGGACGAGGTGGTGATCACCTCGAAGT
TCGGCTGGAACATCGACCTGGAAACCGGCGAGCGGCTGCCGGGCCTGAACAGCAAGCCCGATCACATCAAGCTGGCGGTC
GACGGTATGCTGAAGCGGCTGCGCACCGACCGCATCGACCTGCTCTATCAGCACCGCGTCGACCCCGAAGTGCCCATCGA
GGATGTCGCCGGCGCGGTCAAGGATCTCGTGGACGAGGGCAAAGTCCTGCATTGGGGGCTTTCGGAGATGGGGCTCGGGA
CGCTGCGCCGCGCCCATGCCGAACTGCCCGTGACGGCCGTCCAGAGCGAGTATTCGATGCTCTGGCGCGGGCCGGAAGAT
GAGGTGCTGTCCGTCTGCGAGGAACTCGGCATCGGCTTCGTGCCGTGGAGCCCGCTCGGTGTCGGCTTCCTGACCGGCGC
GATCGACGCCGGCACCCGCTTCGCCGAGGGCGACATCCGTGGGGTTGAGACACGCTTCGCGCCTGAGAACCTGCCGGCGA
ACCTGGCGCTGGTGGCGCTGCTGAAGGATTGGGCCGGCAGGAAGCAGGCCACCGCCGGACAGATCGCGCTCGCCTGGCTT
CTGGCCCAAAAGCCCTGGATCGTCCCGATCCCCGGCACGACGCAGATGGCGCATATGCTGGAGAACATCGGCGCGGCCGC
GATCAGCTTCACGCCCGACGAGATCTCCGAACTCAACATGGCCGTCGCGGCGATCGAGCTGCGCGGCCAACGTCTCCCCG
ACGCCGTTCTGGCCTTCTCGAATGTCGAGGCTCCGGCAAGGAATTAA

Upstream 100 bases:

>100_bases
CGTGCGGGGCGACCGCTATCCGGCATCCCACCAGCAATTCGTCAACCGCTGAGGGCGCGCCGTTCAGACGCGACCTCTCC
CGAACACAAGGACAACAGAC

Downstream 100 bases:

>100_bases
GGAAGTAGACATGAAAAGCAGAAATCTAGGAAATCTTGAGGTCTCGGCCCTCGGCCTCGGCTGCATGGGGATGACGGGCG
TTTACGGTCCGGGCGTCGAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTNEQKLKIGRRGFLGAAGGLAAAPLLVSTGSGVSAQEAAQGTGIYATAPSLSGRRMLGTLEVSSIGLGVQNMHRTYQTT
IPSRPEMINIIRTAHDRGVTFFDTAEAYGPHECERILGEAVEPFRDEVVITSKFGWNIDLETGERLPGLNSKPDHIKLAV
DGMLKRLRTDRIDLLYQHRVDPEVPIEDVAGAVKDLVDEGKVLHWGLSEMGLGTLRRAHAELPVTAVQSEYSMLWRGPED
EVLSVCEELGIGFVPWSPLGVGFLTGAIDAGTRFAEGDIRGVETRFAPENLPANLALVALLKDWAGRKQATAGQIALAWL
LAQKPWIVPIPGTTQMAHMLENIGAAAISFTPDEISELNMAVAAIELRGQRLPDAVLAFSNVEAPARN

Sequences:

>Translated_388_residues
MTNEQKLKIGRRGFLGAAGGLAAAPLLVSTGSGVSAQEAAQGTGIYATAPSLSGRRMLGTLEVSSIGLGVQNMHRTYQTT
IPSRPEMINIIRTAHDRGVTFFDTAEAYGPHECERILGEAVEPFRDEVVITSKFGWNIDLETGERLPGLNSKPDHIKLAV
DGMLKRLRTDRIDLLYQHRVDPEVPIEDVAGAVKDLVDEGKVLHWGLSEMGLGTLRRAHAELPVTAVQSEYSMLWRGPED
EVLSVCEELGIGFVPWSPLGVGFLTGAIDAGTRFAEGDIRGVETRFAPENLPANLALVALLKDWAGRKQATAGQIALAWL
LAQKPWIVPIPGTTQMAHMLENIGAAAISFTPDEISELNMAVAAIELRGQRLPDAVLAFSNVEAPARN
>Mature_387_residues
TNEQKLKIGRRGFLGAAGGLAAAPLLVSTGSGVSAQEAAQGTGIYATAPSLSGRRMLGTLEVSSIGLGVQNMHRTYQTTI
PSRPEMINIIRTAHDRGVTFFDTAEAYGPHECERILGEAVEPFRDEVVITSKFGWNIDLETGERLPGLNSKPDHIKLAVD
GMLKRLRTDRIDLLYQHRVDPEVPIEDVAGAVKDLVDEGKVLHWGLSEMGLGTLRRAHAELPVTAVQSEYSMLWRGPEDE
VLSVCEELGIGFVPWSPLGVGFLTGAIDAGTRFAEGDIRGVETRFAPENLPANLALVALLKDWAGRKQATAGQIALAWLL
AQKPWIVPIPGTTQMAHMLENIGAAAISFTPDEISELNMAVAAIELRGQRLPDAVLAFSNVEAPARN

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=344, Percent_Identity=27.6162790697674, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI4504825, Length=303, Percent_Identity=29.3729372937294, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI27436969, Length=303, Percent_Identity=29.3729372937294, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI27436964, Length=286, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436966, Length=286, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436962, Length=286, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI41152114, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI223718702, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI41327764, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081735, Length=314, Percent_Identity=30.8917197452229, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789375, Length=297, Percent_Identity=28.2828282828283, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788070, Length=298, Percent_Identity=30.2013422818792, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787674, Length=310, Percent_Identity=28.7096774193548, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788081, Length=286, Percent_Identity=24.4755244755245, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI48994888, Length=279, Percent_Identity=28.3154121863799, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789199, Length=333, Percent_Identity=26.4264264264264, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=305, Percent_Identity=29.1803278688525, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=295, Percent_Identity=26.1016949152542, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=291, Percent_Identity=25.085910652921, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=26.5625, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325384, Length=315, Percent_Identity=26.984126984127, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=297, Percent_Identity=24.9158249158249, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45549126, Length=213, Percent_Identity=29.5774647887324, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640980, Length=213, Percent_Identity=29.5774647887324, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41838; Mature: 41707

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEQKLKIGRRGFLGAAGGLAAAPLLVSTGSGVSAQEAAQGTGIYATAPSLSGRRMLGT
CCCCHHHHHCCCCCCCCCCCHHHCCEEEECCCCCCHHHHHCCCCEEEECCCCCCCEEEEE
LEVSSIGLGVQNMHRTYQTTIPSRPEMINIIRTAHDRGVTFFDTAEAYGPHECERILGEA
EEHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
VEPFRDEVVITSKFGWNIDLETGERLPGLNSKPDHIKLAVDGMLKRLRTDRIDLLYQHRV
HCCHHCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC
DPEVPIEDVAGAVKDLVDEGKVLHWGLSEMGLGTLRRAHAELPVTAVQSEYSMLWRGPED
CCCCCHHHHHHHHHHHHHCCCEEEECHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
EVLSVCEELGIGFVPWSPLGVGFLTGAIDAGTRFAEGDIRGVETRFAPENLPANLALVAL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCHHHHHHH
LKDWAGRKQATAGQIALAWLLAQKPWIVPIPGTTQMAHMLENIGAAAISFTPDEISELNM
HHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEECHHHHHHHHH
AVAAIELRGQRLPDAVLAFSNVEAPARN
HHHHHHHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TNEQKLKIGRRGFLGAAGGLAAAPLLVSTGSGVSAQEAAQGTGIYATAPSLSGRRMLGT
CCCHHHHHCCCCCCCCCCCHHHCCEEEECCCCCCHHHHHCCCCEEEECCCCCCCEEEEE
LEVSSIGLGVQNMHRTYQTTIPSRPEMINIIRTAHDRGVTFFDTAEAYGPHECERILGEA
EEHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
VEPFRDEVVITSKFGWNIDLETGERLPGLNSKPDHIKLAVDGMLKRLRTDRIDLLYQHRV
HCCHHCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC
DPEVPIEDVAGAVKDLVDEGKVLHWGLSEMGLGTLRRAHAELPVTAVQSEYSMLWRGPED
CCCCCHHHHHHHHHHHHHCCCEEEECHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
EVLSVCEELGIGFVPWSPLGVGFLTGAIDAGTRFAEGDIRGVETRFAPENLPANLALVAL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCHHHHHHH
LKDWAGRKQATAGQIALAWLLAQKPWIVPIPGTTQMAHMLENIGAAAISFTPDEISELNM
HHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEECHHHHHHHHH
AVAAIELRGQRLPDAVLAFSNVEAPARN
HHHHHHHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]