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The map label for this gene is purQ [H]

Identifier: 119385687

GI number: 119385687

Start: 131180

End: 131848

Strand: Direct

Name: purQ [H]

Synonym: Pden_2962

Alternate gene names: 119385687

Gene position: 131180-131848 (Clockwise)

Preceding gene: 119385686

Following gene: 119385688

Centisome position: 7.58

GC content: 69.66

Gene sequence:

>669_bases
ATGAAAGCTGCCGTCATCACCTTTCCCGGATCGAATTGCGACCGCGATCTGGCCGTCGCCTTGCAGCAGGCGGGTGCCGA
GGTCGCGCGGGTCTGGCACAAGGACGAGGCGCTGCCGGCGGGCACCGACCTGGTCGCGGTGCCGGGCGGGTTCTCGTTCG
GGGACTACCTGCGCTGCGGCGCCATCGCCGCGCATTCGCCCATCGCCGGCGCGATCAAGGCCCATGCGGCGCGCGGCGGC
TATGTGCTGGGCATCTGCAACGGCTTTCAGGTGCTGACCGAGCTGAACCTGCTGCCGGGCGCGCTGATGCGCAATGCCGG
GTTGCGCTTTTTGTGCCGCGAGGCGGTGCTGCGGGTGGCGACCGCGGCGAGCCCCTTTACCGCGGCCTATGCCCCGGGCG
AGGAGATCCGCGTGCCGGTCGCCCATCACGACGGCAATTACCAGATCGATCCCGAGGGGCTGGCGGCGCTGAAGGACCAG
GACCGCATCGCCTTTACCTATGCGCCGGGCGTCAATGGTTCGGTCGAGGATATCGCCGGGGTGCTGTCCGAGAACCGCCG
GGTGCTGGGCATGATGCCGCATCCCGAGCGCGCCGCCGATCCGGCGCATGGCGGCACCGATGGCGCGAGGCTGTTTGCCT
CGCTGGTGCAGGAGCTTGTCGCGGCCTGA

Upstream 100 bases:

>100_bases
ATTTGGGGAACGAAGAAGTCCGCTGGGCGGTGCAAAGCGGCTTAACACGCGATCCTGCTTGGAGTATGGGAGGCGCGAGG
CATTATCCCGGAGGCCCGCC

Downstream 100 bases:

>100_bases
CTTGAGCGGCGCCCTTTCGCGCACTAGACTGCATCGACCCCCAGTCGGGGGCGGTGCCGGAGGCTCATGCAAGAGGAAGA
CAATTCCATCGGGTTCCCGG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKAAVITFPGSNCDRDLAVALQQAGAEVARVWHKDEALPAGTDLVAVPGGFSFGDYLRCGAIAAHSPIAGAIKAHAARGG
YVLGICNGFQVLTELNLLPGALMRNAGLRFLCREAVLRVATAASPFTAAYAPGEEIRVPVAHHDGNYQIDPEGLAALKDQ
DRIAFTYAPGVNGSVEDIAGVLSENRRVLGMMPHPERAADPAHGGTDGARLFASLVQELVAA

Sequences:

>Translated_222_residues
MKAAVITFPGSNCDRDLAVALQQAGAEVARVWHKDEALPAGTDLVAVPGGFSFGDYLRCGAIAAHSPIAGAIKAHAARGG
YVLGICNGFQVLTELNLLPGALMRNAGLRFLCREAVLRVATAASPFTAAYAPGEEIRVPVAHHDGNYQIDPEGLAALKDQ
DRIAFTYAPGVNGSVEDIAGVLSENRRVLGMMPHPERAADPAHGGTDGARLFASLVQELVAA
>Mature_222_residues
MKAAVITFPGSNCDRDLAVALQQAGAEVARVWHKDEALPAGTDLVAVPGGFSFGDYLRCGAIAAHSPIAGAIKAHAARGG
YVLGICNGFQVLTELNLLPGALMRNAGLRFLCREAVLRVATAASPFTAAYAPGEEIRVPVAHHDGNYQIDPEGLAALKDQ
DRIAFTYAPGVNGSVEDIAGVLSENRRVLGMMPHPERAADPAHGGTDGARLFASLVQELVAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=242, Percent_Identity=30.9917355371901, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI48994899, Length=257, Percent_Identity=29.5719844357977, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=234, Percent_Identity=29.0598290598291, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24582111, Length=234, Percent_Identity=29.0598290598291, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582109, Length=234, Percent_Identity=29.0598290598291, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17137292, Length=234, Percent_Identity=29.0598290598291, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23135; Mature: 23135

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVITFPGSNCDRDLAVALQQAGAEVARVWHKDEALPAGTDLVAVPGGFSFGDYLRCG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHC
AIAAHSPIAGAIKAHAARGGYVLGICNGFQVLTELNLLPGALMRNAGLRFLCREAVLRVA
HHHCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHH
TAASPFTAAYAPGEEIRVPVAHHDGNYQIDPEGLAALKDQDRIAFTYAPGVNGSVEDIAG
HCCCCCEEECCCCCCEEEEEEECCCCEEECHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
VLSENRRVLGMMPHPERAADPAHGGTDGARLFASLVQELVAA
HHHCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAAVITFPGSNCDRDLAVALQQAGAEVARVWHKDEALPAGTDLVAVPGGFSFGDYLRCG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHC
AIAAHSPIAGAIKAHAARGGYVLGICNGFQVLTELNLLPGALMRNAGLRFLCREAVLRVA
HHHCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHH
TAASPFTAAYAPGEEIRVPVAHHDGNYQIDPEGLAALKDQDRIAFTYAPGVNGSVEDIAG
HCCCCCEEECCCCCCEEEEEEECCCCEEECHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
VLSENRRVLGMMPHPERAADPAHGGTDGARLFASLVQELVAA
HHHCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA