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The map label for this gene is nodT [H]

Identifier: 119385668

GI number: 119385668

Start: 109715

End: 111163

Strand: Direct

Name: nodT [H]

Synonym: Pden_2943

Alternate gene names: 119385668

Gene position: 109715-111163 (Clockwise)

Preceding gene: 119385667

Following gene: 119385669

Centisome position: 6.34

GC content: 73.84

Gene sequence:

>1449_bases
ATGATCCAGACCTTGCCTCTTTCCCGCCGCGGCCTGCTGGGCGGGCTTGTCTCGACCCTGGCGCTGGCCGCCTGCAACCC
GGTCAGCCATACCGCGCCCCGCGCCGAGGTGGCCGGCGCATTCGCCGCCAGTTCCCCGGCCCGCCGCGCCGGCGCCAACG
CCTGGTGGGCGGCATTTCGCGACAAGCGGCTGGACGGGCTGATCGCCGCCGGGCTGAATCGCAACCTGGACGTGCAGACC
GCCGTCGCCACCATCCGCGAGGCGCAGGCCAATGCGCGGCTGGTCGGCGCCAGCGACCTGCCGCAGGTCGAGGCGCAGGG
CGCGGCGGCGCGCAACCGCAGCGAGACCGGCATCGTCGAAAGCAGCTCGGCCACGCTGGGCGTGTCCTGGCTGGTCGATC
TGTTCGGCCAGAACCGGGCGGCGCGGCAGGGCGCCTCGGCCCGGCTGGACGCGGCCTATCTGTCGGCCGAGGTGGCGCGG
CTGACCGTGGCAAGCGCCATCGCCTCGGCCTATGTCGACGCGCGCTATTACCAGGAGGCGCTGGCGCTGACCCGGCAAAG
CCTGACCAGCCGCAAGCGCACGCTGGAGATGACCCGCACCCAGGACGCCTTCGGCAGCGTCTCGCGGCTGGAGGTGCTGC
AGGCCGAGCAACTGGTGGCTCAGGCCGAGGCGGCGCTGCCCGGGCTGGAGGTCGGCTTCGACCAGTCGGTGAACCGGCTG
GCCACGCTGACCGCCGGGCGCAGCGCCGATCTGGCGGCGCAGCTGCGCCAGGGCGGCGGCCAGCCGCGCGCCCGCTACAG
CGCCAGCGTCGGCGTGCCGGCCGACGTGGTCCGGGTGCGTCCCGACGTGCGCATGGCCGAGCGCAACCTGGCCGCCGCCG
CCGCCGATGTGGGCGAGGCGCAGGCGGCCTTCTATCCGCGGCTGACGCTGTCCGGCTCGATCACGCCGACGAATATCGGC
GGCGGTGGCAGCAGCAAGAGCTGGGGCTTCGGGCCGCAGATCTCGCTGCCGCTGTTCTCGGGCGGGGCGAACCAGGCGCA
GCTTTCCGCCGCGCAGGCGCGGGCGGAACAGGCGCGGCTGGCCTGGCAGGCCTCGGTCCTGGGCGCGGTCGAGGAGGTCG
AGAACGCGCTGGCCGGCTATAACCGCGACGCCCGCGCCGTCGCCGCGCAATCGCGGCTGGTCGAGAATGCGCGCGAGACG
GTGAACCTGACCCGCAGCTCCTATGAGCTGGGCGAGGCGGATTTCTTCCCGGTCCTGGATGCCGAGCGCAGCCTGCTGTC
GGCCCGGCAGGAACTGGCCGCGGCGGTGCGCCAGCAGGCGCTGAACTTCGTCGCGCTCAGCGCCGCCTCGGCCGGGGGTG
TCGGCCTGCCCGCCACCTCAGGGATTGACCGCCCGGCGGGAAACGGCCATGTTCCCCTCACGTCAGGGGAGTCCCGCCTA
GGGGACTGA

Upstream 100 bases:

>100_bases
CTCCGGCGCCGCCGCAAGGCACGGGCGGGACCAAGGCCGCCCGTGCCGCCATTTCCCTTTCCGCGACCCCAGCCGGGCCG
CGTTCAACAGAGAGTTTCGG

Downstream 100 bases:

>100_bases
GAGGCTGACAGGGACCGCCCATGGGCGGTTCCGGTGAAGCGACCCTTTGAACCTGACCCAGTTGATGCTGGCGTAGGAAG
ACCGAAGGGCAGCTTTCCCC

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MIQTLPLSRRGLLGGLVSTLALAACNPVSHTAPRAEVAGAFAASSPARRAGANAWWAAFRDKRLDGLIAAGLNRNLDVQT
AVATIREAQANARLVGASDLPQVEAQGAAARNRSETGIVESSSATLGVSWLVDLFGQNRAARQGASARLDAAYLSAEVAR
LTVASAIASAYVDARYYQEALALTRQSLTSRKRTLEMTRTQDAFGSVSRLEVLQAEQLVAQAEAALPGLEVGFDQSVNRL
ATLTAGRSADLAAQLRQGGGQPRARYSASVGVPADVVRVRPDVRMAERNLAAAAADVGEAQAAFYPRLTLSGSITPTNIG
GGGSSKSWGFGPQISLPLFSGGANQAQLSAAQARAEQARLAWQASVLGAVEEVENALAGYNRDARAVAAQSRLVENARET
VNLTRSSYELGEADFFPVLDAERSLLSARQELAAAVRQQALNFVALSAASAGGVGLPATSGIDRPAGNGHVPLTSGESRL
GD

Sequences:

>Translated_482_residues
MIQTLPLSRRGLLGGLVSTLALAACNPVSHTAPRAEVAGAFAASSPARRAGANAWWAAFRDKRLDGLIAAGLNRNLDVQT
AVATIREAQANARLVGASDLPQVEAQGAAARNRSETGIVESSSATLGVSWLVDLFGQNRAARQGASARLDAAYLSAEVAR
LTVASAIASAYVDARYYQEALALTRQSLTSRKRTLEMTRTQDAFGSVSRLEVLQAEQLVAQAEAALPGLEVGFDQSVNRL
ATLTAGRSADLAAQLRQGGGQPRARYSASVGVPADVVRVRPDVRMAERNLAAAAADVGEAQAAFYPRLTLSGSITPTNIG
GGGSSKSWGFGPQISLPLFSGGANQAQLSAAQARAEQARLAWQASVLGAVEEVENALAGYNRDARAVAAQSRLVENARET
VNLTRSSYELGEADFFPVLDAERSLLSARQELAAAVRQQALNFVALSAASAGGVGLPATSGIDRPAGNGHVPLTSGESRL
GD
>Mature_482_residues
MIQTLPLSRRGLLGGLVSTLALAACNPVSHTAPRAEVAGAFAASSPARRAGANAWWAAFRDKRLDGLIAAGLNRNLDVQT
AVATIREAQANARLVGASDLPQVEAQGAAARNRSETGIVESSSATLGVSWLVDLFGQNRAARQGASARLDAAYLSAEVAR
LTVASAIASAYVDARYYQEALALTRQSLTSRKRTLEMTRTQDAFGSVSRLEVLQAEQLVAQAEAALPGLEVGFDQSVNRL
ATLTAGRSADLAAQLRQGGGQPRARYSASVGVPADVVRVRPDVRMAERNLAAAAADVGEAQAAFYPRLTLSGSITPTNIG
GGGSSKSWGFGPQISLPLFSGGANQAQLSAAQARAEQARLAWQASVLGAVEEVENALAGYNRDARAVAAQSRLVENARET
VNLTRSSYELGEADFFPVLDAERSLLSARQELAAAVRQQALNFVALSAASAGGVGLPATSGIDRPAGNGHVPLTSGESRL
GD

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=410, Percent_Identity=27.3170731707317, Blast_Score=138, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50065; Mature: 50065

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTLPLSRRGLLGGLVSTLALAACNPVSHTAPRAEVAGAFAASSPARRAGANAWWAAFR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHH
DKRLDGLIAAGLNRNLDVQTAVATIREAQANARLVGASDLPQVEAQGAAARNRSETGIVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCHHCCCCCCCEEE
SSSATLGVSWLVDLFGQNRAARQGASARLDAAYLSAEVARLTVASAIASAYVDARYYQEA
CCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTRQSLTSRKRTLEMTRTQDAFGSVSRLEVLQAEQLVAQAEAALPGLEVGFDQSVNRL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ATLTAGRSADLAAQLRQGGGQPRARYSASVGVPADVVRVRPDVRMAERNLAAAAADVGEA
HHHCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCCH
QAAFYPRLTLSGSITPTNIGGGGSSKSWGFGPQISLPLFSGGANQAQLSAAQARAEQARL
HHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECEEECCCCCHHHHHHHHHHHHHHHH
AWQASVLGAVEEVENALAGYNRDARAVAAQSRLVENARETVNLTRSSYELGEADFFPVLD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
AERSLLSARQELAAAVRQQALNFVALSAASAGGVGLPATSGIDRPAGNGHVPLTSGESRL
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GD
CC
>Mature Secondary Structure
MIQTLPLSRRGLLGGLVSTLALAACNPVSHTAPRAEVAGAFAASSPARRAGANAWWAAFR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHH
DKRLDGLIAAGLNRNLDVQTAVATIREAQANARLVGASDLPQVEAQGAAARNRSETGIVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCHHCCCCCCCEEE
SSSATLGVSWLVDLFGQNRAARQGASARLDAAYLSAEVARLTVASAIASAYVDARYYQEA
CCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTRQSLTSRKRTLEMTRTQDAFGSVSRLEVLQAEQLVAQAEAALPGLEVGFDQSVNRL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ATLTAGRSADLAAQLRQGGGQPRARYSASVGVPADVVRVRPDVRMAERNLAAAAADVGEA
HHHCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCCH
QAAFYPRLTLSGSITPTNIGGGGSSKSWGFGPQISLPLFSGGANQAQLSAAQARAEQARL
HHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECEEECCCCCHHHHHHHHHHHHHHHH
AWQASVLGAVEEVENALAGYNRDARAVAAQSRLVENARETVNLTRSSYELGEADFFPVLD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
AERSLLSARQELAAAVRQQALNFVALSAASAGGVGLPATSGIDRPAGNGHVPLTSGESRL
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]