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The map label for this gene is bioD [H]

Identifier: 119385643

GI number: 119385643

Start: 81340

End: 81948

Strand: Direct

Name: bioD [H]

Synonym: Pden_2918

Alternate gene names: 119385643

Gene position: 81340-81948 (Clockwise)

Preceding gene: 119385642

Following gene: 119385644

Centisome position: 4.7

GC content: 74.06

Gene sequence:

>609_bases
GTGATCGTCGTGGGCACCGATACGGGCATCGGCAAGACCGTGTTCAGCGCCGGGCTGGCCCGCGCGCTGGGCGCGAGTTA
TTGGAAGCCGGTGCAGGCGGGGCTGGAGGAGGAGACCGACAGCGAGGTCGTGGCGCGGCTTTCGGGCCGGCCGGTGCTGG
CCGAGGCGTATCGGCTGCGCCTGCCCGCCTCGCCGCATCTGGCGGCCGAGCGCGAGGGGGTGGCGATCGATCCGGCGCGG
CTGGCCTTGCCCCCGGTGGCCCCGCTGGTGGTCGAGGGCGCGGGCGGGCTGATGGTGCCGCTGACCCGGCACCTGCTCTA
TTTGCAGGTGATCGCGGGCTGGGGGGCGCCGGTGGTGCTGTGCTGCCGCACCGCGCTGGGCACGATCAACCATTCGCTGC
TGTCGCTGACGGCGCTGCGGGCGGCCGGTTGCCGGGTGGCGGGCGTGGCCTTCATCGGCGAGGAGATGGCGGACAGCCGG
CGGGTGATCTGCGAGATCGGCGCGGTGCGCGACCTGGGCCGGCTGCCGGTGCTGGAGCGGGTGACGGCCGAGGCGCTGGC
CGATGCCTTTGCCGGCATCGACCTGGCGGCGATCCGCGAGGTGTCGTGA

Upstream 100 bases:

>100_bases
TGCCGAAGGGGACGGCGCGGCTGCGGGTCTCGGTCACCGGCAATGTCGGGGCGGGCGAGATCGCGGCGCTGTTTGCCGCG
CTGGAGGCAGCATGGGTGCG

Downstream 100 bases:

>100_bases
TGCGGGATCTGGCGTTCGACCGGCGGCATCTGTGGCATCCCTACAGCTCGATGCGCGAGCCGGGGCCGGTGCATGAGGTC
GCGGCGGCCGAGGGGGTCTG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MIVVGTDTGIGKTVFSAGLARALGASYWKPVQAGLEEETDSEVVARLSGRPVLAEAYRLRLPASPHLAAEREGVAIDPAR
LALPPVAPLVVEGAGGLMVPLTRHLLYLQVIAGWGAPVVLCCRTALGTINHSLLSLTALRAAGCRVAGVAFIGEEMADSR
RVICEIGAVRDLGRLPVLERVTAEALADAFAGIDLAAIREVS

Sequences:

>Translated_202_residues
MIVVGTDTGIGKTVFSAGLARALGASYWKPVQAGLEEETDSEVVARLSGRPVLAEAYRLRLPASPHLAAEREGVAIDPAR
LALPPVAPLVVEGAGGLMVPLTRHLLYLQVIAGWGAPVVLCCRTALGTINHSLLSLTALRAAGCRVAGVAFIGEEMADSR
RVICEIGAVRDLGRLPVLERVTAEALADAFAGIDLAAIREVS
>Mature_202_residues
MIVVGTDTGIGKTVFSAGLARALGASYWKPVQAGLEEETDSEVVARLSGRPVLAEAYRLRLPASPHLAAEREGVAIDPAR
LALPPVAPLVVEGAGGLMVPLTRHLLYLQVIAGWGAPVVLCCRTALGTINHSLLSLTALRAAGCRVAGVAFIGEEMADSR
RVICEIGAVRDLGRLPVLERVTAEALADAFAGIDLAAIREVS

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=202, Percent_Identity=30.6930693069307, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324385, Length=188, Percent_Identity=37.2340425531915, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 21051; Mature: 21051

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVGTDTGIGKTVFSAGLARALGASYWKPVQAGLEEETDSEVVARLSGRPVLAEAYRLR
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHC
LPASPHLAAEREGVAIDPARLALPPVAPLVVEGAGGLMVPLTRHLLYLQVIAGWGAPVVL
CCCCCCCCCCCCCCEECHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHH
CCRTALGTINHSLLSLTALRAAGCRVAGVAFIGEEMADSRRVICEIGAVRDLGRLPVLER
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
VTAEALADAFAGIDLAAIREVS
HHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MIVVGTDTGIGKTVFSAGLARALGASYWKPVQAGLEEETDSEVVARLSGRPVLAEAYRLR
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHC
LPASPHLAAEREGVAIDPARLALPPVAPLVVEGAGGLMVPLTRHLLYLQVIAGWGAPVVL
CCCCCCCCCCCCCCEECHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHH
CCRTALGTINHSLLSLTALRAAGCRVAGVAFIGEEMADSRRVICEIGAVRDLGRLPVLER
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
VTAEALADAFAGIDLAAIREVS
HHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA