Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 119358354

GI number: 119358354

Start: 2960820

End: 2961755

Strand: Direct

Name: aroB [H]

Synonym: Cpha266_2586

Alternate gene names: 119358354

Gene position: 2960820-2961755 (Clockwise)

Preceding gene: 119358353

Following gene: 119358380

Centisome position: 94.48

GC content: 55.34

Gene sequence:

>936_bases
ATGAAACGAATCTCATGCATAGACATCGGCACCAACACAGCACTCCTGCTCATTGCCGATCTCGACCCGAAAACCGGACA
AATCATACCGGTCTGTCACAAACAGACCATCATACGGCTCGGCAAAAACGTTGACGAAGAGCGACAAATCGGATCGGAAG
CCCTTCACCGGCTGGTATCCTGCATGCATGATTACGGCCGTATCAGCGCCGAATACTCCTCCGCAACCACCATAGCCGTC
GGAACAAGCGCCCTCAGAGACGCGAAAAACCGCGACGCAATCATCGAAGCCGTAGCCGAAGCCACAAACATCAAAATCTC
CTGCATCAGCGGCCATGAAGAGGCCGAACTCACCTTTTTCGGAGCAATCGCCGGCACCAACGAAATTCCCGACCTCTTTT
CCGTTATCGATATCGGCGGCGGCAGCACCGAAATCTCCATGGGAACGCCCGAAAAACTCACGCAAAGCATCAGCCTCGAC
ATCGGTTCGGTACGACTGACCGAACGCCATTTCACCACGCTCCCTCCATCGCCAGACGAACTTCTGGCGGCAAAAGAGAC
GATCAACGCCACGCTCGCCGCACCGACGATCCCCTTTCTGGCCGCACGCGAAAACGTCTTCGGCGTAGCAGGAACGCTCA
CCACGATAGCGCAGCTCAGCCAGGGACTCCGCCATTTCGACGCCGAAAAAGTGCATCACTACCCGCTCTCCTACGCCGAA
GTACGCAAACTGCTCGAAAAGCTCAAAACAAGCACGCTTCAGGAGATCGTCAACATGGGCATACCCGAAGGACGAGCCGA
CGTCATCACCATGGGCACATTAATTCTGCTCCAGATCATGCGTCTCCTCGGCATCGGAGAAATCCGGGTCAGCATTCAGG
GTCTGCGTTTCGGTCTGGCACAGAAGGAACTGCATCGTCTCCAGAAAAACATCTGA

Upstream 100 bases:

>100_bases
ACGAACCGTGGCTGAAAAAACTCCTGAAAAAACTCAACTACCAGATCGAAAAAACCATCTACGAAGACGAATGGCTCTCC
AGCCTTGTCCGCCCGACGCC

Downstream 100 bases:

>100_bases
GAGCATAGATGCAGAACGGATGGCCCGCAGCATCTCTGGTAAAAAAAATAAAAACCCGCTCGCTCTCAACAAGTCGGTAT
TTTTTACGAAGCTCTTCCGC

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKRISCIDIGTNTALLLIADLDPKTGQIIPVCHKQTIIRLGKNVDEERQIGSEALHRLVSCMHDYGRISAEYSSATTIAV
GTSALRDAKNRDAIIEAVAEATNIKISCISGHEEAELTFFGAIAGTNEIPDLFSVIDIGGGSTEISMGTPEKLTQSISLD
IGSVRLTERHFTTLPPSPDELLAAKETINATLAAPTIPFLAARENVFGVAGTLTTIAQLSQGLRHFDAEKVHHYPLSYAE
VRKLLEKLKTSTLQEIVNMGIPEGRADVITMGTLILLQIMRLLGIGEIRVSIQGLRFGLAQKELHRLQKNI

Sequences:

>Translated_311_residues
MKRISCIDIGTNTALLLIADLDPKTGQIIPVCHKQTIIRLGKNVDEERQIGSEALHRLVSCMHDYGRISAEYSSATTIAV
GTSALRDAKNRDAIIEAVAEATNIKISCISGHEEAELTFFGAIAGTNEIPDLFSVIDIGGGSTEISMGTPEKLTQSISLD
IGSVRLTERHFTTLPPSPDELLAAKETINATLAAPTIPFLAARENVFGVAGTLTTIAQLSQGLRHFDAEKVHHYPLSYAE
VRKLLEKLKTSTLQEIVNMGIPEGRADVITMGTLILLQIMRLLGIGEIRVSIQGLRFGLAQKELHRLQKNI
>Mature_311_residues
MKRISCIDIGTNTALLLIADLDPKTGQIIPVCHKQTIIRLGKNVDEERQIGSEALHRLVSCMHDYGRISAEYSSATTIAV
GTSALRDAKNRDAIIEAVAEATNIKISCISGHEEAELTFFGAIAGTNEIPDLFSVIDIGGGSTEISMGTPEKLTQSISLD
IGSVRLTERHFTTLPPSPDELLAAKETINATLAAPTIPFLAARENVFGVAGTLTTIAQLSQGLRHFDAEKVHHYPLSYAE
VRKLLEKLKTSTLQEIVNMGIPEGRADVITMGTLILLQIMRLLGIGEIRVSIQGLRFGLAQKELHRLQKNI

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=303, Percent_Identity=27.0627062706271, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788848, Length=300, Percent_Identity=25.6666666666667, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33741; Mature: 33741

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISCIDIGTNTALLLIADLDPKTGQIIPVCHKQTIIRLGKNVDEERQIGSEALHRLVS
CCCEEEEEECCCCEEEEEEECCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
CMHDYGRISAEYSSATTIAVGTSALRDAKNRDAIIEAVAEATNIKISCISGHEEAELTFF
HHHHHHCCEECCCCCEEEEECHHHHHHCCCHHHHHHHHHHHHCEEEEEECCCCCCEEEEE
GAIAGTNEIPDLFSVIDIGGGSTEISMGTPEKLTQSISLDIGSVRLTERHFTTLPPSPDE
EEECCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHH
LLAAKETINATLAAPTIPFLAARENVFGVAGTLTTIAQLSQGLRHFDAEKVHHYPLSYAE
HHHHHHHHHHEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHH
VRKLLEKLKTSTLQEIVNMGIPEGRADVITMGTLILLQIMRLLGIGEIRVSIQGLRFGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHH
QKELHRLQKNI
HHHHHHHHHCC
>Mature Secondary Structure
MKRISCIDIGTNTALLLIADLDPKTGQIIPVCHKQTIIRLGKNVDEERQIGSEALHRLVS
CCCEEEEEECCCCEEEEEEECCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
CMHDYGRISAEYSSATTIAVGTSALRDAKNRDAIIEAVAEATNIKISCISGHEEAELTFF
HHHHHHCCEECCCCCEEEEECHHHHHHCCCHHHHHHHHHHHHCEEEEEECCCCCCEEEEE
GAIAGTNEIPDLFSVIDIGGGSTEISMGTPEKLTQSISLDIGSVRLTERHFTTLPPSPDE
EEECCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHH
LLAAKETINATLAAPTIPFLAARENVFGVAGTLTTIAQLSQGLRHFDAEKVHHYPLSYAE
HHHHHHHHHHEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHH
VRKLLEKLKTSTLQEIVNMGIPEGRADVITMGTLILLQIMRLLGIGEIRVSIQGLRFGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHH
QKELHRLQKNI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]