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The map label for this gene is infC

Identifier: 119358270

GI number: 119358270

Start: 2870994

End: 2871623

Strand: Direct

Name: infC

Synonym: Cpha266_2502

Alternate gene names: 119358270

Gene position: 2870994-2871623 (Clockwise)

Preceding gene: 119358269

Following gene: 119358271

Centisome position: 91.61

GC content: 46.19

Gene sequence:

>630_bases
ATGAAGAAACAGAAGACCACGACTCAGAAACCGAAACTTTCCTACAGGATCAATGAACAGATCCGTGTTCCGGAAGTCAG
GATTATCTTTCCGGACGGTACGCAGCAGGTCATGAAAACCATTGATGCAAAACGGCTTGCCGAAGAGAAAAACTTTGACC
TGATCGAGGTTCAGCCAAATGCTGATCCGCCGGTCTGCAAACTTGATAACCTTGGAAAGCTGATCTATAAAATGGATAAG
CGAGACAAGGATCTCAAGAAAAAGCAGAAAACGACAACGCTGAAAGAACTGCGGTTTCATCCCAACACCGACAAGCACGA
TTTTGATTTCAAGACCGCGCATCTTGAAGAATTTCTGCGCAAGGGAAACAGGGTCAGGGCAACGATTGTTTTTTTAGGCC
GTTCAATAATATACAAAGACAGAGGCCTTGAACTTGCCGAACGCCTTACGGAAAGACTCAGTTGCGTCAGCAACCGGGAT
GGAGACCCTAAGTTTGAAGGAAAAAAACTGTTCGTGTATTTCGAGCCCGACAAAAAAAAGGTGGACGCTTTTGAACGCAT
AAAAGCCAAAACAGGTGTGCCGCAGCAACCTCTGGCGCCACTGCCTCCATCAGAGGACATCGAAGAATAA

Upstream 100 bases:

>100_bases
CACCGGTGACGAAGGTCTTTTCACCACAGACTCGCTGATAGACAAGCTCAAAAAGGAAATAGCGGCAAAAACCCTGATCC
TCTAAACAAACCTTGATCGC

Downstream 100 bases:

>100_bases
TCACGAACCTGCTCATTTTTATATAAAACAAAAGAGACCATCATGCCTAAAATGAAATCACATCGCGGAGCATGCAAGCG
ATTCAAAGCTACCGCATCAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKKQKTTTQKPKLSYRINEQIRVPEVRIIFPDGTQQVMKTIDAKRLAEEKNFDLIEVQPNADPPVCKLDNLGKLIYKMDK
RDKDLKKKQKTTTLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDRGLELAERLTERLSCVSNRD
GDPKFEGKKLFVYFEPDKKKVDAFERIKAKTGVPQQPLAPLPPSEDIEE

Sequences:

>Translated_209_residues
MKKQKTTTQKPKLSYRINEQIRVPEVRIIFPDGTQQVMKTIDAKRLAEEKNFDLIEVQPNADPPVCKLDNLGKLIYKMDK
RDKDLKKKQKTTTLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDRGLELAERLTERLSCVSNRD
GDPKFEGKKLFVYFEPDKKKVDAFERIKAKTGVPQQPLAPLPPSEDIEE
>Mature_209_residues
MKKQKTTTQKPKLSYRINEQIRVPEVRIIFPDGTQQVMKTIDAKRLAEEKNFDLIEVQPNADPPVCKLDNLGKLIYKMDK
RDKDLKKKQKTTTLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDRGLELAERLTERLSCVSNRD
GDPKFEGKKLFVYFEPDKKKVDAFERIKAKTGVPQQPLAPLPPSEDIEE

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=179, Percent_Identity=35.195530726257, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CHLPD (A1BJB3)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912914.1
- ProteinModelPortal:   A1BJB3
- STRING:   A1BJB3
- GeneID:   4569589
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2502
- NMPDR:   fig|290317.7.peg.2618
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 24397; Mature: 24397

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQKTTTQKPKLSYRINEQIRVPEVRIIFPDGTQQVMKTIDAKRLAEEKNFDLIEVQPN
CCCCCCCCCCCCEEEEECCEEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
ADPPVCKLDNLGKLIYKMDKRDKDLKKKQKTTTLKELRFHPNTDKHDFDFKTAHLEEFLR
CCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
KGNRVRATIVFLGRSIIYKDRGLELAERLTERLSCVSNRDGDPKFEGKKLFVYFEPDKKK
CCCCEEEEEEEECCHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHH
VDAFERIKAKTGVPQQPLAPLPPSEDIEE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKQKTTTQKPKLSYRINEQIRVPEVRIIFPDGTQQVMKTIDAKRLAEEKNFDLIEVQPN
CCCCCCCCCCCCEEEEECCEEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
ADPPVCKLDNLGKLIYKMDKRDKDLKKKQKTTTLKELRFHPNTDKHDFDFKTAHLEEFLR
CCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
KGNRVRATIVFLGRSIIYKDRGLELAERLTERLSCVSNRDGDPKFEGKKLFVYFEPDKKK
CCCCEEEEEEEECCHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHH
VDAFERIKAKTGVPQQPLAPLPPSEDIEE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA