Click here to switch to the map view.

The map label for this gene is pqqL [C]

Identifier: 119358063

GI number: 119358063

Start: 2622474

End: 2623796

Strand: Direct

Name: pqqL [C]

Synonym: Cpha266_2291

Alternate gene names: 119358063

Gene position: 2622474-2623796 (Clockwise)

Preceding gene: 119358058

Following gene: 119358064

Centisome position: 83.68

GC content: 47.62

Gene sequence:

>1323_bases
ATGAAAAACAACCAATCCCATGCGAAAATTTTTACCGTAATGCCAAGAGAAAGTTCATCACAAAAGCATCCTGTGACAGC
TGCCGTCATCGGTGACACAACGCTTCCGAACGGCTTGCGCATCCTCACTGATTATGTACCATGGGTGCAAAGCGTTACCC
TTGGTATTCACGTCAATGCAGGATCGAGGGATGACCCGAAAAAACAGAGCGGACTTGCCCATTTTATTGAACACGCTGTT
TTTAAAGGCACAAAAACAAGAAACTATCTCGATATCGCCGGCAGCATAGAAAAAAATGGCGGCTATCTTGACGCCTATAC
CACAAAAGAGCAGACCTGTATCTATCTTCGCTGCCTTAACCGCTTTGTTGAACCATCGCTCGACCTTCTTGCCGATCTGG
TATGCAATCCGATCTTTCCAGCCGAAGAGATTGAAAAAGAAAAAGAGGTCGTACTTGAAGAGATAAGCAGCATCAACGAC
ACCCCGGAAGAGCTGGTTTTTGAAGAATTTGATCAGCTTCTATTCAACAAGCATCCCCTTGGCCGCCCGATTCTCGGAAC
GAACAAAAGCGTCAGCAGCCTTTCGGAACATGATCTTGAAGAGTTCATGCTGCAGCACTACTGCCCTGAAAACATGATCC
TCACGGCAACCGGCAATGTCGATCATGAGGAGCTCGTCGTACTTGCAGAGCGATTTTTCACCCCATTGAATGCCCGAAAC
ACCCGGAAATCGACCCGAAAGCTTTTTCAAACGGAGCGCTATCAGCCGTTCAGCCTCACCATGAAAAAAAAAATCTTTCA
GGCTCAGATTATTGTCGGCACGCTCCTGCCACGAAAAGATCCGCTTTTTTACCCTCTGATGGTACTCAACACCCTGCTTG
GAGGCGGCATGAGTTCGCTTTTGAACCTTGAACTGAGGGAAAAATCAGGAATTGCCTACAGCTCCTACTCATCCGTCAGT
TTTTTCGATGACATCACCGTGCTGAACATCTATACCGGAGCAGACAGCAACAAGGTAAAACGAGCACTTGAGATCATCAC
AAGGATCCTCGAAAGTCCACAGCTTCACTCCCCTGCTGAAGAAGATCTCCTCGCCGCAAAATCAAGACTGCTTGGATCCT
TTATCATGGGAACCGAAAAAATGACACGAAGAATGTCCCATGTGGCAACCGACATCACCTATTTCGGCAGATACGTGCCG
CTGGAAGAAAAAATCGCGTCCATTGAGGCCGTTACTGCGGAACATATTAACGAAGCTGCTCAGTTCATGCTCGCAGAGGT
GCCGATATCAACCCTTGTCTATAAGCCGGGCAGACAATCCTGA

Upstream 100 bases:

>100_bases
TATCTCACGATATATGCCAAGTTCCAGCATCACGTGAAACCGCCGTTATAAACATCGCGGAACTCCCTGTTTACAAAAAT
AAGAATTAAAACTACATTGC

Downstream 100 bases:

>100_bases
CAACGAGCGATACTTTTAAAAAACTTGATTAATGTGTATCTTAATAACTTTTATTTTTAATCATTACTAATCAACCCAGA
CCGCCTTGCAAAAGAATATT

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKNNQSHAKIFTVMPRESSSQKHPVTAAVIGDTTLPNGLRILTDYVPWVQSVTLGIHVNAGSRDDPKKQSGLAHFIEHAV
FKGTKTRNYLDIAGSIEKNGGYLDAYTTKEQTCIYLRCLNRFVEPSLDLLADLVCNPIFPAEEIEKEKEVVLEEISSIND
TPEELVFEEFDQLLFNKHPLGRPILGTNKSVSSLSEHDLEEFMLQHYCPENMILTATGNVDHEELVVLAERFFTPLNARN
TRKSTRKLFQTERYQPFSLTMKKKIFQAQIIVGTLLPRKDPLFYPLMVLNTLLGGGMSSLLNLELREKSGIAYSSYSSVS
FFDDITVLNIYTGADSNKVKRALEIITRILESPQLHSPAEEDLLAAKSRLLGSFIMGTEKMTRRMSHVATDITYFGRYVP
LEEKIASIEAVTAEHINEAAQFMLAEVPISTLVYKPGRQS

Sequences:

>Translated_440_residues
MKNNQSHAKIFTVMPRESSSQKHPVTAAVIGDTTLPNGLRILTDYVPWVQSVTLGIHVNAGSRDDPKKQSGLAHFIEHAV
FKGTKTRNYLDIAGSIEKNGGYLDAYTTKEQTCIYLRCLNRFVEPSLDLLADLVCNPIFPAEEIEKEKEVVLEEISSIND
TPEELVFEEFDQLLFNKHPLGRPILGTNKSVSSLSEHDLEEFMLQHYCPENMILTATGNVDHEELVVLAERFFTPLNARN
TRKSTRKLFQTERYQPFSLTMKKKIFQAQIIVGTLLPRKDPLFYPLMVLNTLLGGGMSSLLNLELREKSGIAYSSYSSVS
FFDDITVLNIYTGADSNKVKRALEIITRILESPQLHSPAEEDLLAAKSRLLGSFIMGTEKMTRRMSHVATDITYFGRYVP
LEEKIASIEAVTAEHINEAAQFMLAEVPISTLVYKPGRQS
>Mature_440_residues
MKNNQSHAKIFTVMPRESSSQKHPVTAAVIGDTTLPNGLRILTDYVPWVQSVTLGIHVNAGSRDDPKKQSGLAHFIEHAV
FKGTKTRNYLDIAGSIEKNGGYLDAYTTKEQTCIYLRCLNRFVEPSLDLLADLVCNPIFPAEEIEKEKEVVLEEISSIND
TPEELVFEEFDQLLFNKHPLGRPILGTNKSVSSLSEHDLEEFMLQHYCPENMILTATGNVDHEELVVLAERFFTPLNARN
TRKSTRKLFQTERYQPFSLTMKKKIFQAQIIVGTLLPRKDPLFYPLMVLNTLLGGGMSSLLNLELREKSGIAYSSYSSVS
FFDDITVLNIYTGADSNKVKRALEIITRILESPQLHSPAEEDLLAAKSRLLGSFIMGTEKMTRRMSHVATDITYFGRYVP
LEEKIASIEAVTAEHINEAAQFMLAEVPISTLVYKPGRQS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=399, Percent_Identity=28.8220551378446, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI46593007, Length=197, Percent_Identity=33.502538071066, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24308013, Length=362, Percent_Identity=28.1767955801105, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1787770, Length=213, Percent_Identity=25.3521126760563, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=416, Percent_Identity=26.6826923076923, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17553678, Length=402, Percent_Identity=26.865671641791, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17510601, Length=430, Percent_Identity=22.3255813953488, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=419, Percent_Identity=26.9689737470167, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6321813, Length=411, Percent_Identity=23.3576642335766, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357875, Length=404, Percent_Identity=28.2178217821782, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24646943, Length=404, Percent_Identity=28.2178217821782, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI19921772, Length=434, Percent_Identity=25.5760368663594, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667786, Length=343, Percent_Identity=24.198250728863, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641429, Length=185, Percent_Identity=28.6486486486486, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49493; Mature: 49493

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNQSHAKIFTVMPRESSSQKHPVTAAVIGDTTLPNGLRILTDYVPWVQSVTLGIHVNA
CCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEEECC
GSRDDPKKQSGLAHFIEHAVFKGTKTRNYLDIAGSIEKNGGYLDAYTTKEQTCIYLRCLN
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCEECCCCEEEEECCCCHHHHHHHHHH
RFVEPSLDLLADLVCNPIFPAEEIEKEKEVVLEEISSINDTPEELVFEEFDQLLFNKHPL
HHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
GRPILGTNKSVSSLSEHDLEEFMLQHYCPENMILTATGNVDHEELVVLAERFFTPLNARN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
TRKSTRKLFQTERYQPFSLTMKKKIFQAQIIVGTLLPRKDPLFYPLMVLNTLLGGGMSSL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHH
LNLELREKSGIAYSSYSSVSFFDDITVLNIYTGADSNKVKRALEIITRILESPQLHSPAE
HEEEEHHCCCCEEECCCCCCHHCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCH
EDLLAAKSRLLGSFIMGTEKMTRRMSHVATDITYFGRYVPLEEKIASIEAVTAEHINEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
QFMLAEVPISTLVYKPGRQS
HHHHHHCCHHHHEECCCCCC
>Mature Secondary Structure
MKNNQSHAKIFTVMPRESSSQKHPVTAAVIGDTTLPNGLRILTDYVPWVQSVTLGIHVNA
CCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEEECC
GSRDDPKKQSGLAHFIEHAVFKGTKTRNYLDIAGSIEKNGGYLDAYTTKEQTCIYLRCLN
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCEECCCCEEEEECCCCHHHHHHHHHH
RFVEPSLDLLADLVCNPIFPAEEIEKEKEVVLEEISSINDTPEELVFEEFDQLLFNKHPL
HHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
GRPILGTNKSVSSLSEHDLEEFMLQHYCPENMILTATGNVDHEELVVLAERFFTPLNARN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
TRKSTRKLFQTERYQPFSLTMKKKIFQAQIIVGTLLPRKDPLFYPLMVLNTLLGGGMSSL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHH
LNLELREKSGIAYSSYSSVSFFDDITVLNIYTGADSNKVKRALEIITRILESPQLHSPAE
HEEEEHHCCCCEEECCCCCCHHCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCH
EDLLAAKSRLLGSFIMGTEKMTRRMSHVATDITYFGRYVPLEEKIASIEAVTAEHINEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
QFMLAEVPISTLVYKPGRQS
HHHHHHCCHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]