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The map label for this gene is tig

Identifier: 119358064

GI number: 119358064

Start: 2623882

End: 2625165

Strand: Direct

Name: tig

Synonym: Cpha266_2292

Alternate gene names: 119358064

Gene position: 2623882-2625165 (Clockwise)

Preceding gene: 119358063

Following gene: 119358066

Centisome position: 83.73

GC content: 47.2

Gene sequence:

>1284_bases
TTGCAAAAGAATATTACGAAAGTCAGCGATACCGAGCAGGAGCTTGAAATCATTCTCACTGCTGAAGAATACGGAACAGA
ATACAATCAGGAACTTGATGAAGCGAAAAGAACGATACAGGTCAAAGGCTTCAGAAAAGGGCACGTCCCGACAGGTTTGA
TCAAAAAACTCGCAGGCCCGGCTATTGAAGCATCGGTTGCCGAAAAAATGGCATCAAAACATTTCGGAACAATCGTTGAC
GAAGAAAAAATCAAGCCCGCAAGCCGCGCGCAGATTGAAAGCGTCAGTTATGAGGGCGATGAACTCAAAATCAAGCTCTC
CTACGAAATACATCCCGTGTTCGAGCTTAACAACTACAGCGATTACACCTTCACGAAAGCCCGGTACACCATAACCGACG
AGGATGTTCAAAAAGAGATCGATCTGATCCTTAAAGGTCACGGATCGCTTGCGACCGTCGATGAAGCGGCACTTGGAACC
GATACCGTTATCGGCGATGTTGAAAAACTCGATGCCGCCGGCGAGCCGGAAGAGGGTGGCAAAACGGAAAACCACCATTT
CAATCTCGAGTATCTTCCTGAAGACAATCCCTTCCGTATCTCGCTTGAAGGAGCAAAAGCAGGAGAAACCGTCAATGTCG
CAACAACCCAGAAAGACCCGAACACTCCTGTTGTCAGCTACCGTATTACGGTCAAAGAGGTAAAACGTCTTGAACTTCCC
GAACTGACCGATGATCTCGTCAAGGAGATCACCCGTCAACGCTTCGAAACCGTTGCCGACTTCACTGCCGATGTCAGAAT
ACAGCTTGAAGAGCACTTCGGCATGAAATCCGATGAAGAACTGCTTGAATCCATCTCTTCAAAGCTTATCGAGGAAAACC
CGGTTTCAACACCAAAATCCATGGTCGCATCCTTTGCAAACATGCTTGTTGAAAACGCAAAGCGTCAGTTTGGCGGAAAA
TTCCCGAAAGGCTTCGACGAAAGTCAGTTCACGGAATCAATCATCCCCAATGCGGAAAAACATGCCCGCTGGCTTTTGAT
CAGCCAGAAAATAGCCGAACTGAACAATGTCGAAGTTACCGATGAGGACATTAAAACCTATGCGGAAAAAGAGGCGGAGA
AATCCACTCCCGAGCAGAAAGAAGAGATAATGAGCACGTATCAGTCAACGGAGTTCAGAGACTATATCGCCGATACCATT
ATCAAGGACAAAATCTACGACATCATCAAGTCGCAGGTTACCATTACGGAAGAACCAACCCCTGTTCCTGTCCACAAGGC
CTGA

Upstream 100 bases:

>100_bases
GGCAGACAATCCTGACAACGAGCGATACTTTTAAAAAACTTGATTAATGTGTATCTTAATAACTTTTATTTTTAATCATT
ACTAATCAACCCAGACCGCC

Downstream 100 bases:

>100_bases
TCCTTTACAAAGAGAACAAAAAAACACCGCAGGAGAGCAAAGAAATCCTGCGGTGTTTTTTTATATCCTCTCATGATCAT
CGGTAATCGGCTCCGATCTC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQKNITKVSDTEQELEIILTAEEYGTEYNQELDEAKRTIQVKGFRKGHVPTGLIKKLAGPAIEASVAEKMASKHFGTIVD
EEKIKPASRAQIESVSYEGDELKIKLSYEIHPVFELNNYSDYTFTKARYTITDEDVQKEIDLILKGHGSLATVDEAALGT
DTVIGDVEKLDAAGEPEEGGKTENHHFNLEYLPEDNPFRISLEGAKAGETVNVATTQKDPNTPVVSYRITVKEVKRLELP
ELTDDLVKEITRQRFETVADFTADVRIQLEEHFGMKSDEELLESISSKLIEENPVSTPKSMVASFANMLVENAKRQFGGK
FPKGFDESQFTESIIPNAEKHARWLLISQKIAELNNVEVTDEDIKTYAEKEAEKSTPEQKEEIMSTYQSTEFRDYIADTI
IKDKIYDIIKSQVTITEEPTPVPVHKA

Sequences:

>Translated_427_residues
MQKNITKVSDTEQELEIILTAEEYGTEYNQELDEAKRTIQVKGFRKGHVPTGLIKKLAGPAIEASVAEKMASKHFGTIVD
EEKIKPASRAQIESVSYEGDELKIKLSYEIHPVFELNNYSDYTFTKARYTITDEDVQKEIDLILKGHGSLATVDEAALGT
DTVIGDVEKLDAAGEPEEGGKTENHHFNLEYLPEDNPFRISLEGAKAGETVNVATTQKDPNTPVVSYRITVKEVKRLELP
ELTDDLVKEITRQRFETVADFTADVRIQLEEHFGMKSDEELLESISSKLIEENPVSTPKSMVASFANMLVENAKRQFGGK
FPKGFDESQFTESIIPNAEKHARWLLISQKIAELNNVEVTDEDIKTYAEKEAEKSTPEQKEEIMSTYQSTEFRDYIADTI
IKDKIYDIIKSQVTITEEPTPVPVHKA
>Mature_427_residues
MQKNITKVSDTEQELEIILTAEEYGTEYNQELDEAKRTIQVKGFRKGHVPTGLIKKLAGPAIEASVAEKMASKHFGTIVD
EEKIKPASRAQIESVSYEGDELKIKLSYEIHPVFELNNYSDYTFTKARYTITDEDVQKEIDLILKGHGSLATVDEAALGT
DTVIGDVEKLDAAGEPEEGGKTENHHFNLEYLPEDNPFRISLEGAKAGETVNVATTQKDPNTPVVSYRITVKEVKRLELP
ELTDDLVKEITRQRFETVADFTADVRIQLEEHFGMKSDEELLESISSKLIEENPVSTPKSMVASFANMLVENAKRQFGGK
FPKGFDESQFTESIIPNAEKHARWLLISQKIAELNNVEVTDEDIKTYAEKEAEKSTPEQKEEIMSTYQSTEFRDYIADTI
IKDKIYDIIKSQVTITEEPTPVPVHKA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=438, Percent_Identity=22.3744292237443, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_CHLPD (A1BIQ7)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912708.1
- ProteinModelPortal:   A1BIQ7
- SMR:   A1BIQ7
- STRING:   A1BIQ7
- GeneID:   4569396
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2292
- NMPDR:   fig|290317.7.peg.2405
- eggNOG:   COG0544
- HOGENOM:   HBG405050
- OMA:   YIKEKAF
- ProtClustDB:   CLSK638004
- HAMAP:   MF_00303
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 48098; Mature: 48098

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNITKVSDTEQELEIILTAEEYGTEYNQELDEAKRTIQVKGFRKGHVPTGLIKKLAGP
CCCCCCCCCCCCCEEEEEEEEHHHCCHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCCC
AIEASVAEKMASKHFGTIVDEEKIKPASRAQIESVSYEGDELKIKLSYEIHPVFELNNYS
HHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCCCCEEEEEEEEEEEEEEEECCCC
DYTFTKARYTITDEDVQKEIDLILKGHGSLATVDEAALGTDTVIGDVEKLDAAGEPEEGG
CCEEEEEEEEECHHHHHHHHHHHEECCCCEEEHHHHHCCCCHHHCCHHHHCCCCCCCCCC
KTENHHFNLEYLPEDNPFRISLEGAKAGETVNVATTQKDPNTPVVSYRITVKEVKRLELP
CCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHHCCCC
ELTDDLVKEITRQRFETVADFTADVRIQLEEHFGMKSDEELLESISSKLIEENPVSTPKS
CHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHH
MVASFANMLVENAKRQFGGKFPKGFDESQFTESIIPNAEKHARWLLISQKIAELNNVEVT
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEC
DEDIKTYAEKEAEKSTPEQKEEIMSTYQSTEFRDYIADTIIKDKIYDIIKSQVTITEEPT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
PVPVHKA
CCCCCCC
>Mature Secondary Structure
MQKNITKVSDTEQELEIILTAEEYGTEYNQELDEAKRTIQVKGFRKGHVPTGLIKKLAGP
CCCCCCCCCCCCCEEEEEEEEHHHCCHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCCC
AIEASVAEKMASKHFGTIVDEEKIKPASRAQIESVSYEGDELKIKLSYEIHPVFELNNYS
HHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCCCCEEEEEEEEEEEEEEEECCCC
DYTFTKARYTITDEDVQKEIDLILKGHGSLATVDEAALGTDTVIGDVEKLDAAGEPEEGG
CCEEEEEEEEECHHHHHHHHHHHEECCCCEEEHHHHHCCCCHHHCCHHHHCCCCCCCCCC
KTENHHFNLEYLPEDNPFRISLEGAKAGETVNVATTQKDPNTPVVSYRITVKEVKRLELP
CCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHHCCCC
ELTDDLVKEITRQRFETVADFTADVRIQLEEHFGMKSDEELLESISSKLIEENPVSTPKS
CHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHH
MVASFANMLVENAKRQFGGKFPKGFDESQFTESIIPNAEKHARWLLISQKIAELNNVEVT
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEC
DEDIKTYAEKEAEKSTPEQKEEIMSTYQSTEFRDYIADTIIKDKIYDIIKSQVTITEEPT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
PVPVHKA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA