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The map label for this gene is tkt [H]

Identifier: 119357933

GI number: 119357933

Start: 2485520

End: 2487535

Strand: Direct

Name: tkt [H]

Synonym: Cpha266_2148

Alternate gene names: 119357933

Gene position: 2485520-2487535 (Clockwise)

Preceding gene: 119357929

Following gene: 119357934

Centisome position: 79.31

GC content: 51.84

Gene sequence:

>2016_bases
ATGCCGACTGAGCCTATAGATCTGCAGACTATCAACACCGCAAGAGTTCTTGCTGTTGACATGGTTGAAAAAGCCGGTTC
CGGCCATCCGGGTATGCCGCTCGGCGCTGCTCCAATGGCCGTCGTACTCTTTACAAAGATTATGAACCACAATCCCGCCA
ACCCGAAATGGCTGAACCGGGACCGATTTGTTCTTTCTGCCGGGCATGGCTCCGCCCTGCTCTATGCGTTGCTGCACCTG
ACCGGCTATGACCTCTCTCTCGACGACCTGAAATCCTTCAGGCAATGGGAAAGCAAAACTCCGGGACATCCGGAATATGG
CGTGACCCCTGGCGTTGAAATGACTACCGGACCTCTTGGACAGGGAATCTCGACGGCTGTCGGTATGGCTATTGCCGAAA
GATTTTGTGCCAAGCACCTCAACTGCGAAGAACTCGAGCTCATAGATTACTATACCTATGTCATCTGCGGTGACGGAGAC
CTTATGGAAGGAGTCAGCAGCGAAACGGCATCTCTTGCAGGTCATCTGAAGCTGGGCAAGCTGATCTGCCTGTACGACAG
CAACCGAATTTCCATTGAGGGGTCAACAACTCTTGCATTTACAGAAAATGTAGGCCAGCGCTTTCTCGCCTTTGGCTGGC
ATGTGGAACATTTTGATGGCAACGACCCTGATGCTGTTGAGAAGGCTCTTCTTTTTGCCAAAACCCAGAAAGATCGCCCC
TCACTGCTTATCGCACACACCAATATAGGATTCGGCAGCCCCAATAAACAGGATAGCGCGGCGGCTCACGGCGAACCGCT
CGGAAGTAAAGAGGTGATACTGCTGAAGCGTGGGTTTGGATTTCCTGAAGAGAAAACGTTTGAAATTTCCGATGCTGTAA
AAGAACACCTGAAAACCGTCAAAAAGAAAGGTTCCGATCTTGAAGAACGCTGGAATGCGTTACGGCGCACCTATACCGAA
CGATTTCCTGCTGCTTCCGAAGCTCTTGAGGAAAGACTGCAGAACCGCCTGCCCGAAGGGTGGGAAAAACTCCTCCCGGG
CTTTGATTCCTCCGAAAAACTGGCTACCCGGCAAGCCTCGAAAAAGGTTCTTGATGCCATTTGCCACAAACTTCCTTTTC
TTGCAGGCGGCTCGGCCGATCTTGCGCCCTCCTGCGGCACCCTGCTCAATGGCGGTATCGACTTTACGCCGGCACATTAC
AACGGCGCCAACTTGAGATTCGGCGTCAGAGAACATGCCATGGGCGCCATCATCAACGGGATGGCTCTTTCTCAAATCAT
CATCCCCTATGGAGCGACATTTCTGGTTTTCTCTGATTACATGAAACCGGCGCTCCGGCTTGCCGCTCTCATGAAAACGC
ACTCCATCTTTATTTTTACACACGACAGCATCGCTCTTGGCGAAGACGGCCCGACCCACCAGCCGATTGAACAGCTTGCG
ATGCTTCGATCTCTCCCCGGCATGGTGGTTTTGAGACCGGCTGACGCCAATGAAACAAAGGAAGCCTGGAAAATCGCTCT
CACCGCGCGAAGACCTGTTTGTCTGATATTTTCAAGACAGACTCTTCCTGTACTCGACGCTGACCGTTATCCTATCTGTA
GCGGCGTTCGAAAAGGAGGATATATTCTTTCGGAATGGAACAAAGAACCTCAAACGCCAGAACAAGCAGCAATCATCATC
GCCACCGGCGCGGAAGTTCATACTGCTCTCGAAGCACAAAACCGGCTTGCGGAAAACGGCGTATCGGCAAGGGTTGTTTC
CATGCCGTCAACCGAACTGTTTGAAGAACAGCCGCAACCCTATCGTCTCGGCGTGCTTCCCGAAAATATAACAAACAGGG
TAGTGATTGAAGCCGCATCGTCATTCGGCTGGCACCGCTATGCTACTGATCGGGGGAAAATTATCGGCATCGACCATTTC
GGAGCATCAGCGCCAGGCAACGTTACACTTGAAAAATTCGGCTTTACCGCATCTCATATTTTCGATACCGTACAATCGCT
CCTGCATACAGCCTGA

Upstream 100 bases:

>100_bases
ATAAACAAATACCTATATTAAGGGATAAAAACAACTATTCCGTACCTTTTTTTTCAGTTATCTATTCTCCATAACGTCAT
GACTAAACGCTCATTCAACC

Downstream 100 bases:

>100_bases
ATCGAAAAGTCTGCATGGCAAAAAACAGCATATTCCACCCGATCGGTGATGACAGGGAGCTGACTGCGATTGCAGCGGCA
GTGATCATAAGCGCAGCAAA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MPTEPIDLQTINTARVLAVDMVEKAGSGHPGMPLGAAPMAVVLFTKIMNHNPANPKWLNRDRFVLSAGHGSALLYALLHL
TGYDLSLDDLKSFRQWESKTPGHPEYGVTPGVEMTTGPLGQGISTAVGMAIAERFCAKHLNCEELELIDYYTYVICGDGD
LMEGVSSETASLAGHLKLGKLICLYDSNRISIEGSTTLAFTENVGQRFLAFGWHVEHFDGNDPDAVEKALLFAKTQKDRP
SLLIAHTNIGFGSPNKQDSAAAHGEPLGSKEVILLKRGFGFPEEKTFEISDAVKEHLKTVKKKGSDLEERWNALRRTYTE
RFPAASEALEERLQNRLPEGWEKLLPGFDSSEKLATRQASKKVLDAICHKLPFLAGGSADLAPSCGTLLNGGIDFTPAHY
NGANLRFGVREHAMGAIINGMALSQIIIPYGATFLVFSDYMKPALRLAALMKTHSIFIFTHDSIALGEDGPTHQPIEQLA
MLRSLPGMVVLRPADANETKEAWKIALTARRPVCLIFSRQTLPVLDADRYPICSGVRKGGYILSEWNKEPQTPEQAAIII
ATGAEVHTALEAQNRLAENGVSARVVSMPSTELFEEQPQPYRLGVLPENITNRVVIEAASSFGWHRYATDRGKIIGIDHF
GASAPGNVTLEKFGFTASHIFDTVQSLLHTA

Sequences:

>Translated_671_residues
MPTEPIDLQTINTARVLAVDMVEKAGSGHPGMPLGAAPMAVVLFTKIMNHNPANPKWLNRDRFVLSAGHGSALLYALLHL
TGYDLSLDDLKSFRQWESKTPGHPEYGVTPGVEMTTGPLGQGISTAVGMAIAERFCAKHLNCEELELIDYYTYVICGDGD
LMEGVSSETASLAGHLKLGKLICLYDSNRISIEGSTTLAFTENVGQRFLAFGWHVEHFDGNDPDAVEKALLFAKTQKDRP
SLLIAHTNIGFGSPNKQDSAAAHGEPLGSKEVILLKRGFGFPEEKTFEISDAVKEHLKTVKKKGSDLEERWNALRRTYTE
RFPAASEALEERLQNRLPEGWEKLLPGFDSSEKLATRQASKKVLDAICHKLPFLAGGSADLAPSCGTLLNGGIDFTPAHY
NGANLRFGVREHAMGAIINGMALSQIIIPYGATFLVFSDYMKPALRLAALMKTHSIFIFTHDSIALGEDGPTHQPIEQLA
MLRSLPGMVVLRPADANETKEAWKIALTARRPVCLIFSRQTLPVLDADRYPICSGVRKGGYILSEWNKEPQTPEQAAIII
ATGAEVHTALEAQNRLAENGVSARVVSMPSTELFEEQPQPYRLGVLPENITNRVVIEAASSFGWHRYATDRGKIIGIDHF
GASAPGNVTLEKFGFTASHIFDTVQSLLHTA
>Mature_670_residues
PTEPIDLQTINTARVLAVDMVEKAGSGHPGMPLGAAPMAVVLFTKIMNHNPANPKWLNRDRFVLSAGHGSALLYALLHLT
GYDLSLDDLKSFRQWESKTPGHPEYGVTPGVEMTTGPLGQGISTAVGMAIAERFCAKHLNCEELELIDYYTYVICGDGDL
MEGVSSETASLAGHLKLGKLICLYDSNRISIEGSTTLAFTENVGQRFLAFGWHVEHFDGNDPDAVEKALLFAKTQKDRPS
LLIAHTNIGFGSPNKQDSAAAHGEPLGSKEVILLKRGFGFPEEKTFEISDAVKEHLKTVKKKGSDLEERWNALRRTYTER
FPAASEALEERLQNRLPEGWEKLLPGFDSSEKLATRQASKKVLDAICHKLPFLAGGSADLAPSCGTLLNGGIDFTPAHYN
GANLRFGVREHAMGAIINGMALSQIIIPYGATFLVFSDYMKPALRLAALMKTHSIFIFTHDSIALGEDGPTHQPIEQLAM
LRSLPGMVVLRPADANETKEAWKIALTARRPVCLIFSRQTLPVLDADRYPICSGVRKGGYILSEWNKEPQTPEQAAIIIA
TGAEVHTALEAQNRLAENGVSARVVSMPSTELFEEQPQPYRLGVLPENITNRVVIEAASSFGWHRYATDRGKIIGIDHFG
ASAPGNVTLEKFGFTASHIFDTVQSLLHTA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=581, Percent_Identity=27.710843373494, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI4507521, Length=581, Percent_Identity=27.710843373494, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI133778974, Length=578, Percent_Identity=26.4705882352941, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI225637459, Length=581, Percent_Identity=21.342512908778, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI225637463, Length=554, Percent_Identity=21.4801444043321, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI225637461, Length=554, Percent_Identity=21.4801444043321, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1788808, Length=667, Percent_Identity=46.9265367316342, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI48994911, Length=666, Percent_Identity=45.045045045045, Blast_Score=561, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17539652, Length=679, Percent_Identity=24.7422680412371, Blast_Score=181, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=46.7359050445104, Blast_Score=570, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6319593, Length=667, Percent_Identity=46.3268365817091, Blast_Score=548, Evalue=1e-157,
Organism=Drosophila melanogaster, GI45551847, Length=670, Percent_Identity=26.1194029850746, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI45550715, Length=670, Percent_Identity=26.1194029850746, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24645119, Length=643, Percent_Identity=26.5940902021773, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24666278, Length=266, Percent_Identity=33.8345864661654, Blast_Score=132, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73274; Mature: 73143

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTEPIDLQTINTARVLAVDMVEKAGSGHPGMPLGAAPMAVVLFTKIMNHNPANPKWLNR
CCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRFVLSAGHGSALLYALLHLTGYDLSLDDLKSFRQWESKTPGHPEYGVTPGVEMTTGPLG
CEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
QGISTAVGMAIAERFCAKHLNCEELELIDYYTYVICGDGDLMEGVSSETASLAGHLKLGK
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCHHHHCCCHHHHHHHHCEEECC
LICLYDSNRISIEGSTTLAFTENVGQRFLAFGWHVEHFDGNDPDAVEKALLFAKTQKDRP
EEEEEECCEEEECCCEEEEEEHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHCCCCCC
SLLIAHTNIGFGSPNKQDSAAAHGEPLGSKEVILLKRGFGFPEEKTFEISDAVKEHLKTV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHH
KKKGSDLEERWNALRRTYTERFPAASEALEERLQNRLPEGWEKLLPGFDSSEKLATRQAS
HHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHH
KKVLDAICHKLPFLAGGSADLAPSCGTLLNGGIDFTPAHYNGANLRFGVREHAMGAIING
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEECHHHHHHHHHHHH
MALSQIIIPYGATFLVFSDYMKPALRLAALMKTHSIFIFTHDSIALGEDGPTHQPIEQLA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCEEECCCCCCCCHHHHHH
MLRSLPGMVVLRPADANETKEAWKIALTARRPVCLIFSRQTLPVLDADRYPICSGVRKGG
HHHCCCCEEEEECCCCCCCHHHEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHCCCCCC
YILSEWNKEPQTPEQAAIIIATGAEVHTALEAQNRLAENGVSARVVSMPSTELFEEQPQP
EEEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCC
YRLGVLPENITNRVVIEAASSFGWHRYATDRGKIIGIDHFGASAPGNVTLEKFGFTASHI
EEEECCCCCCCCEEEEEECCCCCCEEEECCCCCEEEEECCCCCCCCCEEEHHCCCCHHHH
FDTVQSLLHTA
HHHHHHHHHCC
>Mature Secondary Structure 
PTEPIDLQTINTARVLAVDMVEKAGSGHPGMPLGAAPMAVVLFTKIMNHNPANPKWLNR
CCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRFVLSAGHGSALLYALLHLTGYDLSLDDLKSFRQWESKTPGHPEYGVTPGVEMTTGPLG
CEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
QGISTAVGMAIAERFCAKHLNCEELELIDYYTYVICGDGDLMEGVSSETASLAGHLKLGK
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCHHHHCCCHHHHHHHHCEEECC
LICLYDSNRISIEGSTTLAFTENVGQRFLAFGWHVEHFDGNDPDAVEKALLFAKTQKDRP
EEEEEECCEEEECCCEEEEEEHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHCCCCCC
SLLIAHTNIGFGSPNKQDSAAAHGEPLGSKEVILLKRGFGFPEEKTFEISDAVKEHLKTV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHH
KKKGSDLEERWNALRRTYTERFPAASEALEERLQNRLPEGWEKLLPGFDSSEKLATRQAS
HHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHH
KKVLDAICHKLPFLAGGSADLAPSCGTLLNGGIDFTPAHYNGANLRFGVREHAMGAIING
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEECHHHHHHHHHHHH
MALSQIIIPYGATFLVFSDYMKPALRLAALMKTHSIFIFTHDSIALGEDGPTHQPIEQLA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCEEECCCCCCCCHHHHHH
MLRSLPGMVVLRPADANETKEAWKIALTARRPVCLIFSRQTLPVLDADRYPICSGVRKGG
HHHCCCCEEEEECCCCCCCHHHEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHCCCCCC
YILSEWNKEPQTPEQAAIIIATGAEVHTALEAQNRLAENGVSARVVSMPSTELFEEQPQP
EEEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCC
YRLGVLPENITNRVVIEAASSFGWHRYATDRGKIIGIDHFGASAPGNVTLEKFGFTASHI
EEEECCCCCCCCEEEEEECCCCCCEEEECCCCCEEEEECCCCCCCCCEEEHHCCCCHHHH
FDTVQSLLHTA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]