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The map label for this gene is dapB

Identifier: 119357887

GI number: 119357887

Start: 2428525

End: 2429271

Strand: Reverse

Name: dapB

Synonym: Cpha266_2095

Alternate gene names: 119357887

Gene position: 2429271-2428525 (Counterclockwise)

Preceding gene: 119357888

Following gene: 119357886

Centisome position: 77.52

GC content: 52.74

Gene sequence:

>747_bases
ATGAAGGTTACTTTAGTGGGCAATGGCCGGATGGGGCAACAGGTTGCCGAGGTTATCAGCCGGTCGAACGACCATGAAAT
TGCAGCCGTTCTTGACGTCGATGCCCGGATCACTCCGGAGATATTTCATGGAAGCGACGTGATCATTGACTTTACCGTCA
GACAGGCATTCATGGATAATCTTCCTGCAATGCTCGCCTCCGGAGTTCCGGTCGTTGTCGGCACGACAGGGTGGGACGAT
GCCATGGAGGAGGTTCGACGCATGGTTGCTGATGCCCGGGCATCGCTCATGTATTCGGCCAATTTCTCTCTCGGGGTAAA
CATTTTTTTACGTACCCTGCGGGAGGCCGCCCGATTGATCGCTCCGTTCGGGCAATTCGACATTGCTCTTGAAGAACAGC
ATCATACCGGCAAAGCTGATTTTCCAAGCGGTACGGCACTTCGAGCAGCAGAGCTGGTTCTTGAAGCCAACGGAAGAAAG
CGAACCATCGTCAGGCAGCTTTCGGACAACCGCAAACTTGCCGCTGAAGAGCTTCAGGTTGCGTCAGTGAGGCTTGGCAG
CGTTTTTGGAAAGCATACCGCTTTTATCGACTCCGATGCCGACGAAATTCTTGTAGCTCATACGGCTAAAAGTCGGGCAG
GTTTTGCCGGAGGAGCCGTTCATGCAGCCGAATGGCTCGCAGGGATGCATTGTGAGAAACCCGGATTTTATACCATGGAT
GATTTTCTCAACGAAAGGCTTTCATGA

Upstream 100 bases:

>100_bases
AACGGCGCCGCTGTTTACGGTTGCAAGCAGATTGCCCGAAAGCCGGGATCCGTTGCTGATACAGGGAACCCTCGATTGAG
GATTTGAACAAGAGGAGCGT

Downstream 100 bases:

>100_bases
AAAGAGATATGGCTGCTGATCAGTTGGATCGCCCTTCCCTGCCTGTTTCAGGAAGGGTTTACACCGTGCTGTCAGGTGCG
GTTCTTGTTTTGCTTTCGAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKVTLVGNGRMGQQVAEVISRSNDHEIAAVLDVDARITPEIFHGSDVIIDFTVRQAFMDNLPAMLASGVPVVVGTTGWDD
AMEEVRRMVADARASLMYSANFSLGVNIFLRTLREAARLIAPFGQFDIALEEQHHTGKADFPSGTALRAAELVLEANGRK
RTIVRQLSDNRKLAAEELQVASVRLGSVFGKHTAFIDSDADEILVAHTAKSRAGFAGGAVHAAEWLAGMHCEKPGFYTMD
DFLNERLS

Sequences:

>Translated_248_residues
MKVTLVGNGRMGQQVAEVISRSNDHEIAAVLDVDARITPEIFHGSDVIIDFTVRQAFMDNLPAMLASGVPVVVGTTGWDD
AMEEVRRMVADARASLMYSANFSLGVNIFLRTLREAARLIAPFGQFDIALEEQHHTGKADFPSGTALRAAELVLEANGRK
RTIVRQLSDNRKLAAEELQVASVRLGSVFGKHTAFIDSDADEILVAHTAKSRAGFAGGAVHAAEWLAGMHCEKPGFYTMD
DFLNERLS
>Mature_248_residues
MKVTLVGNGRMGQQVAEVISRSNDHEIAAVLDVDARITPEIFHGSDVIIDFTVRQAFMDNLPAMLASGVPVVVGTTGWDD
AMEEVRRMVADARASLMYSANFSLGVNIFLRTLREAARLIAPFGQFDIALEEQHHTGKADFPSGTALRAAELVLEANGRK
RTIVRQLSDNRKLAAEELQVASVRLGSVFGKHTAFIDSDADEILVAHTAKSRAGFAGGAVHAAEWLAGMHCEKPGFYTMD
DFLNERLS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=202, Percent_Identity=34.1584158415842, Blast_Score=104, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHLPD (A1BI80)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912531.1
- ProteinModelPortal:   A1BI80
- STRING:   A1BI80
- GeneID:   4569626
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2095
- NMPDR:   fig|290317.7.peg.2213
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   KYLAKIM
- ProtClustDB:   CLSK637968
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26983; Mature: 26983

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLVGNGRMGQQVAEVISRSNDHEIAAVLDVDARITPEIFHGSDVIIDFTVRQAFMDN
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEECCCCEEEEHHHHHHHHHC
LPAMLASGVPVVVGTTGWDDAMEEVRRMVADARASLMYSANFSLGVNIFLRTLREAARLI
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
APFGQFDIALEEQHHTGKADFPSGTALRAAELVLEANGRKRTIVRQLSDNRKLAAEELQV
CCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHH
ASVRLGSVFGKHTAFIDSDADEILVAHTAKSRAGFAGGAVHAAEWLAGMHCEKPGFYTMD
HHHHHHHHHCCHHEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEHH
DFLNERLS
HHHHHHCC
>Mature Secondary Structure
MKVTLVGNGRMGQQVAEVISRSNDHEIAAVLDVDARITPEIFHGSDVIIDFTVRQAFMDN
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEECCCCEEEEHHHHHHHHHC
LPAMLASGVPVVVGTTGWDDAMEEVRRMVADARASLMYSANFSLGVNIFLRTLREAARLI
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
APFGQFDIALEEQHHTGKADFPSGTALRAAELVLEANGRKRTIVRQLSDNRKLAAEELQV
CCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHH
ASVRLGSVFGKHTAFIDSDADEILVAHTAKSRAGFAGGAVHAAEWLAGMHCEKPGFYTMD
HHHHHHHHHCCHHEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEHH
DFLNERLS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA