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The map label for this gene is frr [H]

Identifier: 119357866

GI number: 119357866

Start: 2409038

End: 2409598

Strand: Direct

Name: frr [H]

Synonym: Cpha266_2074

Alternate gene names: 119357866

Gene position: 2409038-2409598 (Clockwise)

Preceding gene: 119357865

Following gene: 119357870

Centisome position: 76.87

GC content: 50.09

Gene sequence:

>561_bases
ATGAATGTAAGGGACGTTGCGCAGAGAACTGAACCGAAAATGAAAAAAACCATCGAGGCGTTTCAGCATGAAATCGCTTC
GATCAGAACGGGCAAGGCGACAACAGCTTTGCTTGACCGCGTCAAGGTTGAAGCCTACGGGCAGCAGATGCCGCTCAAAC
AGGTCGGCAACGTTGGCGTTATGGATGTGCATACCCTGATGGTACAGGTATGGGATAAATCCATGGTTTCGGCTACAGAA
CGCGCCATTCGCGATGCCAACCTCGGACTGAACCCTGCCGCCGACGGACAGAGCATCCGGGTCAGCATCCCCCCGCTCAC
CGAAGAGCGCCGGAAAGAGTTTGTCAAACTGACCAAAAAATTTGGCGAGGACTCGAAAGTCTCCCTTCGCAACCTTCGCC
GCGATATGATTCACGAGATCGAAAAGCTCGAAAAAGAGAAAGCGATCAGCGAAGACGATAAAAACAAAGGGAAAAAAGAG
GCTGACGAGATGCTCCACAAATTCGAAAAACAGTTGAACGACCTGATCGTCCTGAAAGAAAAAGAGATTATGGAAGTGTA
A

Upstream 100 bases:

>100_bases
TTTCAACAAACGGTTTGCAAAATCCACAGCAGCTCAGGCGAAAGCACAGTAAGGATACTGGTACTTTCAGCACATTTGCA
TCAATCTATCAGGAACCGAT

Downstream 100 bases:

>100_bases
GCTGTTCACAGGCATTCCGATAGCAGAAAAAGCCGGGGAACTCCCGGCTTTTTCTGCTATCGGTGTTTTTTCCGCCCTCC
TGTAATCAGTTCACCCTGCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNVRDVAQRTEPKMKKTIEAFQHEIASIRTGKATTALLDRVKVEAYGQQMPLKQVGNVGVMDVHTLMVQVWDKSMVSATE
RAIRDANLGLNPAADGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIHEIEKLEKEKAISEDDKNKGKKE
ADEMLHKFEKQLNDLIVLKEKEIMEV

Sequences:

>Translated_186_residues
MNVRDVAQRTEPKMKKTIEAFQHEIASIRTGKATTALLDRVKVEAYGQQMPLKQVGNVGVMDVHTLMVQVWDKSMVSATE
RAIRDANLGLNPAADGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIHEIEKLEKEKAISEDDKNKGKKE
ADEMLHKFEKQLNDLIVLKEKEIMEV
>Mature_186_residues
MNVRDVAQRTEPKMKKTIEAFQHEIASIRTGKATTALLDRVKVEAYGQQMPLKQVGNVGVMDVHTLMVQVWDKSMVSATE
RAIRDANLGLNPAADGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIHEIEKLEKEKAISEDDKNKGKKE
ADEMLHKFEKQLNDLIVLKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=29.5454545454545, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786368, Length=187, Percent_Identity=42.7807486631016, Blast_Score=151, Evalue=3e-38,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21296; Mature: 21296

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRDVAQRTEPKMKKTIEAFQHEIASIRTGKATTALLDRVKVEAYGQQMPLKQVGNVGV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCH
MDVHTLMVQVWDKSMVSATERAIRDANLGLNPAADGQSIRVSIPPLTEERRKEFVKLTKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
FGEDSKVSLRNLRRDMIHEIEKLEKEKAISEDDKNKGKKEADEMLHKFEKQLNDLIVLKE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHEEECH
KEIMEV
HHHHCC
>Mature Secondary Structure
MNVRDVAQRTEPKMKKTIEAFQHEIASIRTGKATTALLDRVKVEAYGQQMPLKQVGNVGV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCH
MDVHTLMVQVWDKSMVSATERAIRDANLGLNPAADGQSIRVSIPPLTEERRKEFVKLTKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
FGEDSKVSLRNLRRDMIHEIEKLEKEKAISEDDKNKGKKEADEMLHKFEKQLNDLIVLKE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHEEECH
KEIMEV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA