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The map label for this gene is xseA [H]

Identifier: 119357870

GI number: 119357870

Start: 2412468

End: 2413676

Strand: Direct

Name: xseA [H]

Synonym: Cpha266_2078

Alternate gene names: 119357870

Gene position: 2412468-2413676 (Clockwise)

Preceding gene: 119357866

Following gene: 119357879

Centisome position: 76.98

GC content: 56.58

Gene sequence:

>1209_bases
ATGAGCACAGCGATTCTTTCGGTCAGCGAACTGACCCGACACATTAAAAACGAGCTTGAGAGTCTTTTTCCCCGGGTGTC
GGTTCGGGGTGAAATATCCAATTGCAAACGGCACAACTCGGGCCACATCTATCTGACGCTGAAAGATGAGGGTGCCCAGA
TACCGGCCGTTATCTGGAAACACCTTGCCGGTCGGCTTGCCGCAGATCTCAGGGACGGACAGACTGTCGTAGCGGAAGGG
CGTCTGGAAGTTTACCCTCCTTCCGGTCGCTATCAGCTTATCTGCACCTCGGTGACCGATGCCGGAGAGGGCGCGCTGCA
GCAGGCGTTTGCCCTGCTTTTGCAGAAACTCTCCAAAGCGGGGTATTTCAGCGCCGAACGAAAAAGAGCGATGCCGAAAA
TCCCCAAAACCATCGGCATCATCACCTCGCCGACCGGAGCCGTTATCGAGGATATGGGCAACACCTTTCATCGCCGCTTC
CCTGCGGTTTCGCTCCGCCTCTTCCCGGTAAGGGTTCAGGGAACGGAGGCCGCCGAAGAGATCTGCTCGGCTATCCGCTA
TTTCAACAATATCAGAGAACCGGATCTCCGGCCCGACCTGCTTATCGTGGCAAGAGGGGGCGGGTCAATGGAGGATCTCC
AGCCGTTCAACGAGGAGATTGTGGCCGATGCCATCTACAACTCTCATATTCCCGTCATCAGTGCGGTAGGGCATGAGACC
GATATCACCATTGCCGATATGGTGGCCGATCTGCGGGCCGGAACGCCCTCTATTGCAGCCGAACTCGCGGTGCCTGACAG
GAGCGAACTGCTGCGGATGATTGAGAACCTTCAAAACAGGCAGGGAACGCTTCTGCAGGCAAAACTTGCCGGCGCGGAGC
TGGAAATTGACTCGTTGCGCAACAGTTATGCATTCAACCGTCCGCTCCTGCACATGAAGCAGTGCGACGATCTGCTGGCG
AATCTTGAGCGGCAGATGGAGCAGTCGGTACGAACAGGCTATCTGCAAACCGCGCAGCGCTACCTTTCCGCCCGCCAGCA
TCTCTCGCTGCTTGATTACAGAAAAACACTTGCGAGAGGGTATGCGCTCGTAAAAAAAGAGGGGGCTGTCGTTACCAGCG
CACAGTGCCTGCATCTTCAGGATCGCACGGAGCTGCTGTTTCATGACGGGAGCGTAACCGCGGTTGTTACTGAACCGGTG
CGTTCCTGA

Upstream 100 bases:

>100_bases
CTCATCACGACATGCCCCGGACTTCGTCCGCCGCTCACGACAATAAAAAGAGATGCCCGAACGTATCTCTTTTCTTTTTT
ACCGAGGTTTTTTCTCTCCT

Downstream 100 bases:

>100_bases
GCAGTTGACGCACAAGCTCAAGGTCTTCATACGTATTGACTCCCGGCGCGTCCCTGGTGGTTTTCACGCACCGGATCCGG
TAGCCGTTTTCGAGAAGACG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSTAILSVSELTRHIKNELESLFPRVSVRGEISNCKRHNSGHIYLTLKDEGAQIPAVIWKHLAGRLAADLRDGQTVVAEG
RLEVYPPSGRYQLICTSVTDAGEGALQQAFALLLQKLSKAGYFSAERKRAMPKIPKTIGIITSPTGAVIEDMGNTFHRRF
PAVSLRLFPVRVQGTEAAEEICSAIRYFNNIREPDLRPDLLIVARGGGSMEDLQPFNEEIVADAIYNSHIPVISAVGHET
DITIADMVADLRAGTPSIAAELAVPDRSELLRMIENLQNRQGTLLQAKLAGAELEIDSLRNSYAFNRPLLHMKQCDDLLA
NLERQMEQSVRTGYLQTAQRYLSARQHLSLLDYRKTLARGYALVKKEGAVVTSAQCLHLQDRTELLFHDGSVTAVVTEPV
RS

Sequences:

>Translated_402_residues
MSTAILSVSELTRHIKNELESLFPRVSVRGEISNCKRHNSGHIYLTLKDEGAQIPAVIWKHLAGRLAADLRDGQTVVAEG
RLEVYPPSGRYQLICTSVTDAGEGALQQAFALLLQKLSKAGYFSAERKRAMPKIPKTIGIITSPTGAVIEDMGNTFHRRF
PAVSLRLFPVRVQGTEAAEEICSAIRYFNNIREPDLRPDLLIVARGGGSMEDLQPFNEEIVADAIYNSHIPVISAVGHET
DITIADMVADLRAGTPSIAAELAVPDRSELLRMIENLQNRQGTLLQAKLAGAELEIDSLRNSYAFNRPLLHMKQCDDLLA
NLERQMEQSVRTGYLQTAQRYLSARQHLSLLDYRKTLARGYALVKKEGAVVTSAQCLHLQDRTELLFHDGSVTAVVTEPV
RS
>Mature_401_residues
STAILSVSELTRHIKNELESLFPRVSVRGEISNCKRHNSGHIYLTLKDEGAQIPAVIWKHLAGRLAADLRDGQTVVAEGR
LEVYPPSGRYQLICTSVTDAGEGALQQAFALLLQKLSKAGYFSAERKRAMPKIPKTIGIITSPTGAVIEDMGNTFHRRFP
AVSLRLFPVRVQGTEAAEEICSAIRYFNNIREPDLRPDLLIVARGGGSMEDLQPFNEEIVADAIYNSHIPVISAVGHETD
ITIADMVADLRAGTPSIAAELAVPDRSELLRMIENLQNRQGTLLQAKLAGAELEIDSLRNSYAFNRPLLHMKQCDDLLAN
LERQMEQSVRTGYLQTAQRYLSARQHLSLLDYRKTLARGYALVKKEGAVVTSAQCLHLQDRTELLFHDGSVTAVVTEPVR
S

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=325, Percent_Identity=39.6923076923077, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 44463; Mature: 44331

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAILSVSELTRHIKNELESLFPRVSVRGEISNCKRHNSGHIYLTLKDEGAQIPAVIWK
CCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHCCCCCCEEEEEECCCCCCCHHHHHH
HLAGRLAADLRDGQTVVAEGRLEVYPPSGRYQLICTSVTDAGEGALQQAFALLLQKLSKA
HHHHHHHHHHCCCCEEEECCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
GYFSAERKRAMPKIPKTIGIITSPTGAVIEDMGNTFHRRFPAVSLRLFPVRVQGTEAAEE
CCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHH
ICSAIRYFNNIREPDLRPDLLIVARGGGSMEDLQPFNEEIVADAIYNSHIPVISAVGHET
HHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHCCCCCEEEECCCCC
DITIADMVADLRAGTPSIAAELAVPDRSELLRMIENLQNRQGTLLQAKLAGAELEIDSLR
CCHHHHHHHHHHCCCCHHHHEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHH
NSYAFNRPLLHMKQCDDLLANLERQMEQSVRTGYLQTAQRYLSARQHLSLLDYRKTLARG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALVKKEGAVVTSAQCLHLQDRTELLFHDGSVTAVVTEPVRS
HHHHCCCCCEEECHHHEEECCCCEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
STAILSVSELTRHIKNELESLFPRVSVRGEISNCKRHNSGHIYLTLKDEGAQIPAVIWK
CCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHCCCCCCEEEEEECCCCCCCHHHHHH
HLAGRLAADLRDGQTVVAEGRLEVYPPSGRYQLICTSVTDAGEGALQQAFALLLQKLSKA
HHHHHHHHHHCCCCEEEECCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
GYFSAERKRAMPKIPKTIGIITSPTGAVIEDMGNTFHRRFPAVSLRLFPVRVQGTEAAEE
CCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHH
ICSAIRYFNNIREPDLRPDLLIVARGGGSMEDLQPFNEEIVADAIYNSHIPVISAVGHET
HHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHCCCCCEEEECCCCC
DITIADMVADLRAGTPSIAAELAVPDRSELLRMIENLQNRQGTLLQAKLAGAELEIDSLR
CCHHHHHHHHHHCCCCHHHHEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHH
NSYAFNRPLLHMKQCDDLLANLERQMEQSVRTGYLQTAQRYLSARQHLSLLDYRKTLARG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALVKKEGAVVTSAQCLHLQDRTELLFHDGSVTAVVTEPVRS
HHHHCCCCCEEECHHHEEECCCCEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]