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The map label for this gene is recG [H]

Identifier: 119357864

GI number: 119357864

Start: 2406540

End: 2408663

Strand: Reverse

Name: recG [H]

Synonym: Cpha266_2072

Alternate gene names: 119357864

Gene position: 2408663-2406540 (Counterclockwise)

Preceding gene: 119357867

Following gene: 119357863

Centisome position: 76.86

GC content: 55.79

Gene sequence:

>2124_bases
ATGACAACGATGCGCTCATCATTGCGTGCGCTTCAGGGCGTAGGGCCCAGGCGGGCGGATACGCTTTCCGAGGCCGGCAT
TCATGATGTCGGTGATCTCTATGACTATTTTCCTCGCCGCTATCTCGACAGGCGGGCCATGCGCAGGATCAGCGAACTGT
TGAATGGAGAGACGGTTACGGTTGTCGGCAGGGTGCTGAAGACCGTGCAGGAGGGTCAGGGCGTCGCCCGGTCGCGGTTC
AAGGTACTGCTTGCCGATGAAACCGGGGTTCTTGAGCTGGTCTGGTTCAGGGGGGTTCGGTATTTTTCAAAAATGCTTGC
CACAGGAGATGTTCTCGCCGTTTTTGGAAAGGTCGGTTATTTCGGACGACAGGCACAGATGCAGCACCCTGATTTCGACA
AGCTCGGTTCGGGGGTTCAGGCCTCCGGCAGCGGCGAAAGCTCTGACCTGGAGTTGTATCATACCGGAAGGATTATTTCG
CTGTACAGCACCAGCGACGCCATGAAACAGGCAGGACTCTCGTCGCGCCAGTTGCGGATGATTCTTCTCAAGGCATTCGA
TGACCATCCGCCCGGCAGGGAGGAGAATCTCAGCGAAGAGATGCTTGCGGCTCACGGGCTCATGCCCCTTGGCGAAGCCT
ATCGTGAAATACATTTTCCCGCTACGCAGGAAACGCTTGCGGCAGCGCGGTATCGCCTCAAATGGACTGAACTCTTCTAC
GCCCAGTTGCTGTTTGCCCTGAGGCGTCAGGAGATCCGGCAGAATAAAACCGCCGCACGATTCGACCACTCAGGAGAGAT
AACCCGCAAACTCTACGAAGCGCTGCCGTTCGATCTTACCGGGGCGCAGAAAACGGTTATCCGCGAAATATATCAGGACC
TCAGAAGCGGATGTCCGATGAACCGGCTGCTTCAGGGCGACGTTGGTTCCGGCAAGACTCTCGTTGCCATGTTTTCCATT
GCGCTTGCAGCCGATAACGGCTTGCAGTCCGCATTTATGGCGCCGACAGAAATTCTTGCCGTCCAGCACTATCTTGCGCT
CAAAAGAGCTTTTCAGCCGCTGGGGCTGAACGTCGGGCTTCTCTCCGGACGACAGCGGAAAAAAGAGCGCGATGCGGTGC
TCGGCGATCTCCGGAACGGCACGATTGCCATTGCGGTAGGAACCCATGCCATGATCGAGGAGGGTGTGACCATGGCCGCT
CTCGGTCTGGTGATCATCGACGAACAGCACCGGTTCGGCGTGTTGCAGCGCAAGGCGCTCCAGGAAAAAGCGCTGAACCC
TCATGTTCTCCTGATGACCGCCACGCCGATTCCCCGAACGCTCTGCATGGGCGTGTTCGGCGATCTCGATGTCTCGGTCA
TCAACGAAATGCCGCCGGGCAGGCAGCCTGTCGTAACAAAACTTCTTGCCGGAAACGAGACCGGCGAGGCCTATACCTCA
ATTATCCGTGAAGTACAAAAAGGACGGCAGGCCTATATTGTCTATCCGATGGTTGAAGAGTCTGAAAAAATCGATCTTAA
GGCCGCCGTTGACCGTTTCGATTTTCTGACGGCAAACATATTTTCCGATCTCCGGCTCGGGCTGATTCACGGAAGAATGA
CGACCGAAAGCAAGGAGAGTGTAATGGATGAGTTCAGAAACGGACGAATCGATGTGCTTGTCGGAACGACCGTGATTGAG
GTTGGCGTGGATGTTCCCAACGCCACCATCATGATGATCGAACATGCCGAGCGGTTCGGACTGGCTCAGTTGCACCAGCT
CAGAGGGAGGGTAGGCCGGGGAAGCCATCCCTCCACCTGTTTTCTCTGTTATGAAAAAACAGCCCCGGATGCGTTGCGTC
GGCTGCATGCCATGGAGTCGGTTGCCGACGGATTCAGGATTTCGAAAATCGACGCCGAAATCAGGGGAACCGGCAATATA
CTTGGCAAAGAGCAGTCCGGCGCGGCAAGCGGTCTGAAGATTGCCGATCTGCAGCATGACGAAGCAATTCTGAACATTGC
GCGAACGGAGGCATTCGCGCTTGTCGCAAAAGATTCGCAGCTCAGGATGCCGGAACACGCTATGATCAGAACCTGTTATT
TGCGTCATTACCATGAGCGCTATGCCCTTGCCGATATCGGATAG

Upstream 100 bases:

>100_bases
ATGACTCTTTTTCTTTCTCGTACAATGAAGAGGTGATATGAACGGCAATAAAATAATAAAGGTGCTAATATACAAGAATT
AATGACGAGTTACAACTGAT

Downstream 100 bases:

>100_bases
CCTTTCCATTGAAACGTTCTGATTGAACAGACAGACGGATATGAAAAAAGAGATTGAAGAAGAGGTCGGGGTCGCTCTTG
AGGGAGTCGTTACCGAAGCA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MTTMRSSLRALQGVGPRRADTLSEAGIHDVGDLYDYFPRRYLDRRAMRRISELLNGETVTVVGRVLKTVQEGQGVARSRF
KVLLADETGVLELVWFRGVRYFSKMLATGDVLAVFGKVGYFGRQAQMQHPDFDKLGSGVQASGSGESSDLELYHTGRIIS
LYSTSDAMKQAGLSSRQLRMILLKAFDDHPPGREENLSEEMLAAHGLMPLGEAYREIHFPATQETLAAARYRLKWTELFY
AQLLFALRRQEIRQNKTAARFDHSGEITRKLYEALPFDLTGAQKTVIREIYQDLRSGCPMNRLLQGDVGSGKTLVAMFSI
ALAADNGLQSAFMAPTEILAVQHYLALKRAFQPLGLNVGLLSGRQRKKERDAVLGDLRNGTIAIAVGTHAMIEEGVTMAA
LGLVIIDEQHRFGVLQRKALQEKALNPHVLLMTATPIPRTLCMGVFGDLDVSVINEMPPGRQPVVTKLLAGNETGEAYTS
IIREVQKGRQAYIVYPMVEESEKIDLKAAVDRFDFLTANIFSDLRLGLIHGRMTTESKESVMDEFRNGRIDVLVGTTVIE
VGVDVPNATIMMIEHAERFGLAQLHQLRGRVGRGSHPSTCFLCYEKTAPDALRRLHAMESVADGFRISKIDAEIRGTGNI
LGKEQSGAASGLKIADLQHDEAILNIARTEAFALVAKDSQLRMPEHAMIRTCYLRHYHERYALADIG

Sequences:

>Translated_707_residues
MTTMRSSLRALQGVGPRRADTLSEAGIHDVGDLYDYFPRRYLDRRAMRRISELLNGETVTVVGRVLKTVQEGQGVARSRF
KVLLADETGVLELVWFRGVRYFSKMLATGDVLAVFGKVGYFGRQAQMQHPDFDKLGSGVQASGSGESSDLELYHTGRIIS
LYSTSDAMKQAGLSSRQLRMILLKAFDDHPPGREENLSEEMLAAHGLMPLGEAYREIHFPATQETLAAARYRLKWTELFY
AQLLFALRRQEIRQNKTAARFDHSGEITRKLYEALPFDLTGAQKTVIREIYQDLRSGCPMNRLLQGDVGSGKTLVAMFSI
ALAADNGLQSAFMAPTEILAVQHYLALKRAFQPLGLNVGLLSGRQRKKERDAVLGDLRNGTIAIAVGTHAMIEEGVTMAA
LGLVIIDEQHRFGVLQRKALQEKALNPHVLLMTATPIPRTLCMGVFGDLDVSVINEMPPGRQPVVTKLLAGNETGEAYTS
IIREVQKGRQAYIVYPMVEESEKIDLKAAVDRFDFLTANIFSDLRLGLIHGRMTTESKESVMDEFRNGRIDVLVGTTVIE
VGVDVPNATIMMIEHAERFGLAQLHQLRGRVGRGSHPSTCFLCYEKTAPDALRRLHAMESVADGFRISKIDAEIRGTGNI
LGKEQSGAASGLKIADLQHDEAILNIARTEAFALVAKDSQLRMPEHAMIRTCYLRHYHERYALADIG
>Mature_706_residues
TTMRSSLRALQGVGPRRADTLSEAGIHDVGDLYDYFPRRYLDRRAMRRISELLNGETVTVVGRVLKTVQEGQGVARSRFK
VLLADETGVLELVWFRGVRYFSKMLATGDVLAVFGKVGYFGRQAQMQHPDFDKLGSGVQASGSGESSDLELYHTGRIISL
YSTSDAMKQAGLSSRQLRMILLKAFDDHPPGREENLSEEMLAAHGLMPLGEAYREIHFPATQETLAAARYRLKWTELFYA
QLLFALRRQEIRQNKTAARFDHSGEITRKLYEALPFDLTGAQKTVIREIYQDLRSGCPMNRLLQGDVGSGKTLVAMFSIA
LAADNGLQSAFMAPTEILAVQHYLALKRAFQPLGLNVGLLSGRQRKKERDAVLGDLRNGTIAIAVGTHAMIEEGVTMAAL
GLVIIDEQHRFGVLQRKALQEKALNPHVLLMTATPIPRTLCMGVFGDLDVSVINEMPPGRQPVVTKLLAGNETGEAYTSI
IREVQKGRQAYIVYPMVEESEKIDLKAAVDRFDFLTANIFSDLRLGLIHGRMTTESKESVMDEFRNGRIDVLVGTTVIEV
GVDVPNATIMMIEHAERFGLAQLHQLRGRVGRGSHPSTCFLCYEKTAPDALRRLHAMESVADGFRISKIDAEIRGTGNIL
GKEQSGAASGLKIADLQHDEAILNIARTEAFALVAKDSQLRMPEHAMIRTCYLRHYHERYALADIG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=714, Percent_Identity=41.0364145658263, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1787357, Length=402, Percent_Identity=38.3084577114428, Blast_Score=265, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78488; Mature: 78356

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMRSSLRALQGVGPRRADTLSEAGIHDVGDLYDYFPRRYLDRRAMRRISELLNGETVT
CCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VVGRVLKTVQEGQGVARSRFKVLLADETGVLELVWFRGVRYFSKMLATGDVLAVFGKVGY
HHHHHHHHHHHCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
FGRQAQMQHPDFDKLGSGVQASGSGESSDLELYHTGRIISLYSTSDAMKQAGLSSRQLRM
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHCCCCHHHHHH
ILLKAFDDHPPGREENLSEEMLAAHGLMPLGEAYREIHFPATQETLAAARYRLKWTELFY
HHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AQLLFALRRQEIRQNKTAARFDHSGEITRKLYEALPFDLTGAQKTVIREIYQDLRSGCPM
HHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCH
NRLLQGDVGSGKTLVAMFSIALAADNGLQSAFMAPTEILAVQHYLALKRAFQPLGLNVGL
HHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEE
LSGRQRKKERDAVLGDLRNGTIAIAVGTHAMIEEGVTMAALGLVIIDEQHRFGVLQRKAL
CCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCHHHHEEEEEECCCHHHHHHHHHHH
QEKALNPHVLLMTATPIPRTLCMGVFGDLDVSVINEMPPGRQPVVTKLLAGNETGEAYTS
HHHCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHCCCCCCHHHHH
IIREVQKGRQAYIVYPMVEESEKIDLKAAVDRFDFLTANIFSDLRLGLIHGRMTTESKES
HHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VMDEFRNGRIDVLVGTTVIEVGVDVPNATIMMIEHAERFGLAQLHQLRGRVGRGSHPSTC
HHHHHHCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEE
FLCYEKTAPDALRRLHAMESVADGFRISKIDAEIRGTGNILGKEQSGAASGLKIADLQHD
EEEEECCCHHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCCCCCCCCEEECCCCH
EAILNIARTEAFALVAKDSQLRMPEHAMIRTCYLRHYHERYALADIG
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTMRSSLRALQGVGPRRADTLSEAGIHDVGDLYDYFPRRYLDRRAMRRISELLNGETVT
CCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VVGRVLKTVQEGQGVARSRFKVLLADETGVLELVWFRGVRYFSKMLATGDVLAVFGKVGY
HHHHHHHHHHHCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
FGRQAQMQHPDFDKLGSGVQASGSGESSDLELYHTGRIISLYSTSDAMKQAGLSSRQLRM
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHCCCCHHHHHH
ILLKAFDDHPPGREENLSEEMLAAHGLMPLGEAYREIHFPATQETLAAARYRLKWTELFY
HHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AQLLFALRRQEIRQNKTAARFDHSGEITRKLYEALPFDLTGAQKTVIREIYQDLRSGCPM
HHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCH
NRLLQGDVGSGKTLVAMFSIALAADNGLQSAFMAPTEILAVQHYLALKRAFQPLGLNVGL
HHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEE
LSGRQRKKERDAVLGDLRNGTIAIAVGTHAMIEEGVTMAALGLVIIDEQHRFGVLQRKAL
CCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCHHHHEEEEEECCCHHHHHHHHHHH
QEKALNPHVLLMTATPIPRTLCMGVFGDLDVSVINEMPPGRQPVVTKLLAGNETGEAYTS
HHHCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHCCCCCCHHHHH
IIREVQKGRQAYIVYPMVEESEKIDLKAAVDRFDFLTANIFSDLRLGLIHGRMTTESKES
HHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VMDEFRNGRIDVLVGTTVIEVGVDVPNATIMMIEHAERFGLAQLHQLRGRVGRGSHPSTC
HHHHHHCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEE
FLCYEKTAPDALRRLHAMESVADGFRISKIDAEIRGTGNILGKEQSGAASGLKIADLQHD
EEEEECCCHHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCCCCCCCCEEECCCCH
EAILNIARTEAFALVAKDSQLRMPEHAMIRTCYLRHYHERYALADIG
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]