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The map label for this gene is accD

Identifier: 119357824

GI number: 119357824

Start: 2349559

End: 2350398

Strand: Reverse

Name: accD

Synonym: Cpha266_2032

Alternate gene names: 119357824

Gene position: 2350398-2349559 (Counterclockwise)

Preceding gene: 119357828

Following gene: 119357822

Centisome position: 75.0

GC content: 49.88

Gene sequence:

>840_bases
ATGGTCTGGTTCAAACGGGCAAAACCTGCGATTCGCACGACCGACAGGCGTGATATGCCGGAAGGCATGTGGTGGAAATG
CGATGAGTGTGGCGCTATGCTGCATAAAAAGCAGCTTGAGGATAACTTTTATACCTGTTCTGAATGCGGTTACCATTTTC
GGATCTCTCCTTACAAGTATTTTTCTCTCCTTTTTGACGGCGATAAGTATCAGGAGTTTGAAGATCAACTGAGAAGTGCC
GACCCTCTCGGGTTTACGGATACGAAAAAATATCTCGACCGTGTTCATGATATTATTGAAAAAAGCGGAAAAACCGAGGC
TTGTCGAAATGCTTTCGGCGAAGCTGACGGCAGGATGCTTGTTGTTTCTGCCATGGACTTCGGTTTTATCGGTGGTTCAA
TGGGTTCGGTCGTCGGCGAAAAGATCGCTCGCGCTGTCGATAAGGCAATCGATCTCAATGCGCCTCTTCTTGTTATTTCA
CAGTCAGGCGGCGCAAGAATGATGGAGGGAGCGTTCAGTCTGATGCAGATGGCTAAAACCGCGGCCCGTCTGACTCGTCT
CAGCGAAAAAAAGCTTCCGTTTTTTTCGCTTATGACCGACCCGACGATGGGGGGGATTACCGCATCGTTTGCCATGCTTG
GCGACGTCAATATCAGCGAACCCAAGGCGCTGATCGGCTTTGCCGGACCGAGAGTAATCAGGGATACCATCAAGAGGGAT
CTGCCTGAAGGGTTTCAGCGTGCCGAGTTTCTTCTTGAGCACGGGTTTCTCGATCTCATTGTTCATCGCAGGGAGTTGAA
AACGCAGATCGTGCGTCTCATGACCATGCTTGCGCCTTAA

Upstream 100 bases:

>100_bases
AAAGCAGCGTGTATGAATCTGCTGTCTGGTTTGTTTTGAGATCTGCCAATGAGTTTATATCTTGAACCTGAATTTATAAC
CTTTAGTTCTAATTGTAAAG

Downstream 100 bases:

>100_bases
CTCCAGCCAAGCGCTTTCGATACAGCGGGGAATCGTTCTGAAAATATGTGTTTTATTTCGATCGCTATTTCCCGGTGTTC
TTTCTGCGTGCTTTCAAGGG

Product: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MVWFKRAKPAIRTTDRRDMPEGMWWKCDECGAMLHKKQLEDNFYTCSECGYHFRISPYKYFSLLFDGDKYQEFEDQLRSA
DPLGFTDTKKYLDRVHDIIEKSGKTEACRNAFGEADGRMLVVSAMDFGFIGGSMGSVVGEKIARAVDKAIDLNAPLLVIS
QSGGARMMEGAFSLMQMAKTAARLTRLSEKKLPFFSLMTDPTMGGITASFAMLGDVNISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFLDLIVHRRELKTQIVRLMTMLAP

Sequences:

>Translated_279_residues
MVWFKRAKPAIRTTDRRDMPEGMWWKCDECGAMLHKKQLEDNFYTCSECGYHFRISPYKYFSLLFDGDKYQEFEDQLRSA
DPLGFTDTKKYLDRVHDIIEKSGKTEACRNAFGEADGRMLVVSAMDFGFIGGSMGSVVGEKIARAVDKAIDLNAPLLVIS
QSGGARMMEGAFSLMQMAKTAARLTRLSEKKLPFFSLMTDPTMGGITASFAMLGDVNISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFLDLIVHRRELKTQIVRLMTMLAP
>Mature_279_residues
MVWFKRAKPAIRTTDRRDMPEGMWWKCDECGAMLHKKQLEDNFYTCSECGYHFRISPYKYFSLLFDGDKYQEFEDQLRSA
DPLGFTDTKKYLDRVHDIIEKSGKTEACRNAFGEADGRMLVVSAMDFGFIGGSMGSVVGEKIARAVDKAIDLNAPLLVIS
QSGGARMMEGAFSLMQMAKTAARLTRLSEKKLPFFSLMTDPTMGGITASFAMLGDVNISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFLDLIVHRRELKTQIVRLMTMLAP

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=131, Percent_Identity=30.5343511450382, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788655, Length=283, Percent_Identity=47.3498233215548, Blast_Score=279, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_CHLPD (A1BI17)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912468.1
- ProteinModelPortal:   A1BI17
- SMR:   A1BI17
- STRING:   A1BI17
- GeneID:   4569152
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2032
- NMPDR:   fig|290317.7.peg.2147
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK637819
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 31481; Mature: 31481

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWFKRAKPAIRTTDRRDMPEGMWWKCDECGAMLHKKQLEDNFYTCSECGYHFRISPYKY
CCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEHHHCCCEEEECHHHE
FSLLFDGDKYQEFEDQLRSADPLGFTDTKKYLDRVHDIIEKSGKTEACRNAFGEADGRML
EHEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEE
VVSAMDFGFIGGSMGSVVGEKIARAVDKAIDLNAPLLVISQSGGARMMEGAFSLMQMAKT
EEEECCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
AARLTRLSEKKLPFFSLMTDPTMGGITASFAMLGDVNISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLLEHGFLDLIVHRRELKTQIVRLMTMLAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVWFKRAKPAIRTTDRRDMPEGMWWKCDECGAMLHKKQLEDNFYTCSECGYHFRISPYKY
CCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEHHHCCCEEEECHHHE
FSLLFDGDKYQEFEDQLRSADPLGFTDTKKYLDRVHDIIEKSGKTEACRNAFGEADGRML
EHEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEE
VVSAMDFGFIGGSMGSVVGEKIARAVDKAIDLNAPLLVISQSGGARMMEGAFSLMQMAKT
EEEECCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
AARLTRLSEKKLPFFSLMTDPTMGGITASFAMLGDVNISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLLEHGFLDLIVHRRELKTQIVRLMTMLAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA