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The map label for this gene is purN [H]

Identifier: 119357771

GI number: 119357771

Start: 2292608

End: 2293210

Strand: Direct

Name: purN [H]

Synonym: Cpha266_1978

Alternate gene names: 119357771

Gene position: 2292608-2293210 (Clockwise)

Preceding gene: 119357769

Following gene: 119357772

Centisome position: 73.16

GC content: 49.42

Gene sequence:

>603_bases
ATGACTAACAGGAAAACCCGTCTTGCTGTATTCTGTTCCGGAGGAGGCAGCAATTTCCAGGCACTGTATCACGCCATAAA
AAGAAAAAAGCTTTCAGCGGAAATCGTTCTCTGCCTGTCAAACCGCTCCCGATGCGGAGCAATGGAGTTTGCCCGCGAGC
ATAAGATCAAGGATGTTCATCTTTCGGAGAAACAGTTCCCCTCTTTCGACGCTTTTACAGAAGCGATGCTTGAAACACTC
CGGAGCAATGAGATTGATCTCATTCTCCTTGCTGGCTACATGCGCAAAGTTCCCGACGCTGTAGTAGGAGCTTTTCCGGA
AAGAATCCTCAACATCCACCCTGCCCTCTTGCCAAAATTCGGAGGAGAGGGCATGTACGGGCTGAATGTTCATGCTGCTG
TTATCGCTTCAGGCGAAACCATCAGCGGAGCAACCGTTCATCTGGTCAATGAAGAGTATGACAAGGGAAGAGTACTCATG
CAGCAAACTGTTCCGGTAATGCCTGACGATAGTGCTGAAAAACTGGCTGAGCGTGTTCTTGCATGTGAGCACCAGCTCTA
TGCCGAAGCTCTTGAAAAGCTGCTGGGAGAACAGGAAGCATGA

Upstream 100 bases:

>100_bases
AAAGCGCTTTCTATACCATCATCGAACAACCTGATTTGCAGGAAAGAAAAAAAATGAATAGAAGCATAGCAACCAATCGT
TTCGCCGAAATAACAAGGAG

Downstream 100 bases:

>100_bases
TCCTGAAAGAGTTGAGCATCAGTGAAATTTTTCACTCGATCCAGGGCGAATCATCCTTTGCCGGATGGCCCTGTGCGTTC
GTCAGACTTGCCGGTTGCGG

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTNRKTRLAVFCSGGGSNFQALYHAIKRKKLSAEIVLCLSNRSRCGAMEFAREHKIKDVHLSEKQFPSFDAFTEAMLETL
RSNEIDLILLAGYMRKVPDAVVGAFPERILNIHPALLPKFGGEGMYGLNVHAAVIASGETISGATVHLVNEEYDKGRVLM
QQTVPVMPDDSAEKLAERVLACEHQLYAEALEKLLGEQEA

Sequences:

>Translated_200_residues
MTNRKTRLAVFCSGGGSNFQALYHAIKRKKLSAEIVLCLSNRSRCGAMEFAREHKIKDVHLSEKQFPSFDAFTEAMLETL
RSNEIDLILLAGYMRKVPDAVVGAFPERILNIHPALLPKFGGEGMYGLNVHAAVIASGETISGATVHLVNEEYDKGRVLM
QQTVPVMPDDSAEKLAERVLACEHQLYAEALEKLLGEQEA
>Mature_199_residues
TNRKTRLAVFCSGGGSNFQALYHAIKRKKLSAEIVLCLSNRSRCGAMEFAREHKIKDVHLSEKQFPSFDAFTEAMLETLR
SNEIDLILLAGYMRKVPDAVVGAFPERILNIHPALLPKFGGEGMYGLNVHAAVIASGETISGATVHLVNEEYDKGRVLMQ
QTVPVMPDDSAEKLAERVLACEHQLYAEALEKLLGEQEA

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=189, Percent_Identity=34.9206349206349, Blast_Score=123, Evalue=8e-29,
Organism=Homo sapiens, GI209869995, Length=189, Percent_Identity=34.9206349206349, Blast_Score=123, Evalue=8e-29,
Organism=Homo sapiens, GI209869993, Length=189, Percent_Identity=34.9206349206349, Blast_Score=123, Evalue=8e-29,
Organism=Escherichia coli, GI1788846, Length=180, Percent_Identity=34.4444444444444, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787483, Length=125, Percent_Identity=32.8, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17567511, Length=193, Percent_Identity=30.5699481865285, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24582400, Length=197, Percent_Identity=35.5329949238579, Blast_Score=133, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 22102; Mature: 21971

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRKTRLAVFCSGGGSNFQALYHAIKRKKLSAEIVLCLSNRSRCGAMEFAREHKIKDVH
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCCCC
LSEKQFPSFDAFTEAMLETLRSNEIDLILLAGYMRKVPDAVVGAFPERILNIHPALLPKF
CCHHCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHCHHHHHHHHHHHHHHCCHHHHCCC
GGEGMYGLNVHAAVIASGETISGATVHLVNEEYDKGRVLMQQTVPVMPDDSAEKLAERVL
CCCCEECCEEEEEEEECCCCCCCCEEEEECCCCCCCCEEHHHCCCCCCCCHHHHHHHHHH
ACEHQLYAEALEKLLGEQEA
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNRKTRLAVFCSGGGSNFQALYHAIKRKKLSAEIVLCLSNRSRCGAMEFAREHKIKDVH
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCCCC
LSEKQFPSFDAFTEAMLETLRSNEIDLILLAGYMRKVPDAVVGAFPERILNIHPALLPKF
CCHHCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHCHHHHHHHHHHHHHHCCHHHHCCC
GGEGMYGLNVHAAVIASGETISGATVHLVNEEYDKGRVLMQQTVPVMPDDSAEKLAERVL
CCCCEECCEEEEEEEECCCCCCCCEEEEECCCCCCCCEEHHHCCCCCCCCHHHHHHHHHH
ACEHQLYAEALEKLLGEQEA
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA