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The map label for this gene is queD [H]

Identifier: 119357643

GI number: 119357643

Start: 2141304

End: 2141735

Strand: Direct

Name: queD [H]

Synonym: Cpha266_1847

Alternate gene names: 119357643

Gene position: 2141304-2141735 (Clockwise)

Preceding gene: 119357633

Following gene: 119357647

Centisome position: 68.33

GC content: 48.61

Gene sequence:

>432_bases
ATGCGCATTTCACGAAAAATCGAGATTGACTACGGCCATACGCTCCCGAACAGTTTCTCGTTCTGCAATCAACTGCATGG
TCATCGCGGGGTGATTGTTGCTACCGTCGAGGGGAAAATGATTGAGCGGACAGGCGGTGATGAAGAGGGGATGGTTATGG
ATTTCAAGTTTCTGAAAGAGATCATGGTGGAGCATATCCACGACAAGCTCGATCATGGTTTTGCGGTGTGGAAAGAAGAC
CATGAAGATCTTGAGTTTATCCTGAAACGCAATTCACGGGTACTGATTACCGATGAACCGCCTACTGCAGAGTGCCTTGC
AAAGTGGGCCTTCAATCAGTTACGGCACCGACTGCCTGAAGGCGTTCTTTTGAGAGAGGTGCGATGGTATGAAACCCCAA
ATAACTGGGCGGATTACGATGGTATCCAGTAA

Upstream 100 bases:

>100_bases
TTTTCTTTTTTTGAATAAAAAATCGCAGGATATTTTATTTTTTTCTTTATTTCTCCGCAGGTAAAAGAACGCCTTTTAGT
TATAACACTGTTTCAAATCC

Downstream 100 bases:

>100_bases
ACCTCTCCTGCCTGTTCAACCGTATTGAACCGACCGGTTGCAATCAACTCTTTCATAACAGACTCTACCTTGGCAAAATC
ATCTGAAAAGCGATCTGCAA

Product: putative 6-pyruvoyl tetrahydropterin synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MRISRKIEIDYGHTLPNSFSFCNQLHGHRGVIVATVEGKMIERTGGDEEGMVMDFKFLKEIMVEHIHDKLDHGFAVWKED
HEDLEFILKRNSRVLITDEPPTAECLAKWAFNQLRHRLPEGVLLREVRWYETPNNWADYDGIQ

Sequences:

>Translated_143_residues
MRISRKIEIDYGHTLPNSFSFCNQLHGHRGVIVATVEGKMIERTGGDEEGMVMDFKFLKEIMVEHIHDKLDHGFAVWKED
HEDLEFILKRNSRVLITDEPPTAECLAKWAFNQLRHRLPEGVLLREVRWYETPNNWADYDGIQ
>Mature_143_residues
MRISRKIEIDYGHTLPNSFSFCNQLHGHRGVIVATVEGKMIERTGGDEEGMVMDFKFLKEIMVEHIHDKLDHGFAVWKED
HEDLEFILKRNSRVLITDEPPTAECLAKWAFNQLRHRLPEGVLLREVRWYETPNNWADYDGIQ

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007116
- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 16805; Mature: 16805

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISRKIEIDYGHTLPNSFSFCNQLHGHRGVIVATVEGKMIERTGGDEEGMVMDFKFLKE
CCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCEEEHHHHHHH
IMVEHIHDKLDHGFAVWKEDHEDLEFILKRNSRVLITDEPPTAECLAKWAFNQLRHRLPE
HHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
GVLLREVRWYETPNNWADYDGIQ
CCEEHHHEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRISRKIEIDYGHTLPNSFSFCNQLHGHRGVIVATVEGKMIERTGGDEEGMVMDFKFLKE
CCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCEEEHHHHHHH
IMVEHIHDKLDHGFAVWKEDHEDLEFILKRNSRVLITDEPPTAECLAKWAFNQLRHRLPE
HHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
GVLLREVRWYETPNNWADYDGIQ
CCEEHHHEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]