Click here to switch to the map view.

The map label for this gene is crtB [H]

Identifier: 119357535

GI number: 119357535

Start: 1963607

End: 1964539

Strand: Direct

Name: crtB [H]

Synonym: Cpha266_1738

Alternate gene names: 119357535

Gene position: 1963607-1964539 (Clockwise)

Preceding gene: 119357523

Following gene: 119357536

Centisome position: 62.66

GC content: 44.69

Gene sequence:

>933_bases
ATGAATTACAGCTACAACGGACAAACCTCCGTGCAGAACGCAGAGAGGCCTACAACTCTTCAGAACTCATATAATTACTG
TCGCCAGATTTCGAAACATCACGCCAAAACCTTTTATCTGGCAAGTCTTTTTCTTCCCAAAAAACAGCAGAATCCTATTT
TCGCCATGTATGCCCTGCTGCGAACGGTGGATGATCTTGTTGACCTTGCCGAAGACAAACTGACCAACGGGCAGATAACC
CGTGATGAAATCAATCGATTGCTTGAAGAGTGGAAAATCCGGCTGAGAAACTGTTATGCCGGCCAGCCGAGCGACGATCC
GATCATGACAGCGTGGCACGACACCATACAACACTATTCCATACCGCTTGAACTTCCGCTCGACCTTATTGACGGCGTGG
CCATGGACATCGAATTCAAGCCATTTGAAACGTTTGACGATCTCTATGTCTATTGCTACAAGGTCGCATCGGTTGTCGGA
CTCATGACATCGGAAATTTTCGGTTACACCAATAAAGATGCACTGCAGCATGCTATTGAACTGGGCATCGCCATGCAATT
GACCAATATCCTCAGGGATATCGGCGAAGATGTCGACAGGAACAGAATTTATCTGCCTCTTGAAGATCTCCGGAAGTTCA
ATTACACCGAAAAGGAGTTCATGCAGAAAAAAATAAATGCCAACTTTCTTGAACTCATGAAATTCCAGATTAACAGAGCA
CGACACTACTATCGATCCTCTGAAAAAGGAATTCCCATGCTTGAAAAAAACAGCCGTTTTGCAGTCATGATCAGCAGTCT
GAACTACAGCAACATTCTCAATGCCATCGAAGAGAACAACTATGACGTTTTTTCACAACGGGCTTACCGGTCGTTTTATC
AGAAAATCAGTACCATTCCCTATGTCTGGTACAAAACCATGATAACCGGCTGA

Upstream 100 bases:

>100_bases
AGCTTGTAAAAAGTTACATATTTTTAGCTGTCACGGCAACAGTGTAAGATGTAAATGCCTGATTGCAGGATAAGAGGCCA
AATAAAAGCACGAATGTCAG

Downstream 100 bases:

>100_bases
TCGCCCGATTTAACGACCCAATCAATAAACAGACCATTGCAGCAAGCATGACGCCTAATGAAAACCCGCAAAGTCCTGGG
AACCCCCAGCAGCTCTCTCT

Product: squalene/phytoene synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNYSYNGQTSVQNAERPTTLQNSYNYCRQISKHHAKTFYLASLFLPKKQQNPIFAMYALLRTVDDLVDLAEDKLTNGQIT
RDEINRLLEEWKIRLRNCYAGQPSDDPIMTAWHDTIQHYSIPLELPLDLIDGVAMDIEFKPFETFDDLYVYCYKVASVVG
LMTSEIFGYTNKDALQHAIELGIAMQLTNILRDIGEDVDRNRIYLPLEDLRKFNYTEKEFMQKKINANFLELMKFQINRA
RHYYRSSEKGIPMLEKNSRFAVMISSLNYSNILNAIEENNYDVFSQRAYRSFYQKISTIPYVWYKTMITG

Sequences:

>Translated_310_residues
MNYSYNGQTSVQNAERPTTLQNSYNYCRQISKHHAKTFYLASLFLPKKQQNPIFAMYALLRTVDDLVDLAEDKLTNGQIT
RDEINRLLEEWKIRLRNCYAGQPSDDPIMTAWHDTIQHYSIPLELPLDLIDGVAMDIEFKPFETFDDLYVYCYKVASVVG
LMTSEIFGYTNKDALQHAIELGIAMQLTNILRDIGEDVDRNRIYLPLEDLRKFNYTEKEFMQKKINANFLELMKFQINRA
RHYYRSSEKGIPMLEKNSRFAVMISSLNYSNILNAIEENNYDVFSQRAYRSFYQKISTIPYVWYKTMITG
>Mature_310_residues
MNYSYNGQTSVQNAERPTTLQNSYNYCRQISKHHAKTFYLASLFLPKKQQNPIFAMYALLRTVDDLVDLAEDKLTNGQIT
RDEINRLLEEWKIRLRNCYAGQPSDDPIMTAWHDTIQHYSIPLELPLDLIDGVAMDIEFKPFETFDDLYVYCYKVASVVG
LMTSEIFGYTNKDALQHAIELGIAMQLTNILRDIGEDVDRNRIYLPLEDLRKFNYTEKEFMQKKINANFLELMKFQINRA
RHYYRSSEKGIPMLEKNSRFAVMISSLNYSNILNAIEENNYDVFSQRAYRSFYQKISTIPYVWYKTMITG

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

Organism=Homo sapiens, GI124517691, Length=306, Percent_Identity=20.9150326797386, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 36455; Mature: 36455

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01045 SQUALEN_PHYTOEN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSYNGQTSVQNAERPTTLQNSYNYCRQISKHHAKTFYLASLFLPKKQQNPIFAMYALL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RTVDDLVDLAEDKLTNGQITRDEINRLLEEWKIRLRNCYAGQPSDDPIMTAWHDTIQHYS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
IPLELPLDLIDGVAMDIEFKPFETFDDLYVYCYKVASVVGLMTSEIFGYTNKDALQHAIE
CCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LGIAMQLTNILRDIGEDVDRNRIYLPLEDLRKFNYTEKEFMQKKINANFLELMKFQINRA
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHH
RHYYRSSEKGIPMLEKNSRFAVMISSLNYSNILNAIEENNYDVFSQRAYRSFYQKISTIP
HHHHHCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCH
YVWYKTMITG
HHHHHHHHCC
>Mature Secondary Structure
MNYSYNGQTSVQNAERPTTLQNSYNYCRQISKHHAKTFYLASLFLPKKQQNPIFAMYALL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RTVDDLVDLAEDKLTNGQITRDEINRLLEEWKIRLRNCYAGQPSDDPIMTAWHDTIQHYS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
IPLELPLDLIDGVAMDIEFKPFETFDDLYVYCYKVASVVGLMTSEIFGYTNKDALQHAIE
CCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LGIAMQLTNILRDIGEDVDRNRIYLPLEDLRKFNYTEKEFMQKKINANFLELMKFQINRA
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHH
RHYYRSSEKGIPMLEKNSRFAVMISSLNYSNILNAIEENNYDVFSQRAYRSFYQKISTIP
HHHHHCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCH
YVWYKTMITG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8018713; 8905231 [H]