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The map label for this gene is lpxD [H]

Identifier: 119357474

GI number: 119357474

Start: 1901049

End: 1902101

Strand: Reverse

Name: lpxD [H]

Synonym: Cpha266_1673

Alternate gene names: 119357474

Gene position: 1902101-1901049 (Counterclockwise)

Preceding gene: 119357481

Following gene: 119357471

Centisome position: 60.69

GC content: 50.71

Gene sequence:

>1053_bases
ATGACGATACAGGATATAATCGTGTACCTTGGGCAGTTTTTTGACAAGGTTGTTCTCGAAGGTTCTGGCGAGGGCGCTAT
AACCGGTCCGGCTAAAATCGAGACCGCCAGACAGGGCCAGGTGAGTTTCGTTTCCAATGAAAAGTATCTCCGGCATCTTG
AAACGACCCAAGCCTCACTGGTTGTTGTACATCTCTCTCTTGATGTTTCGGCATTCAGCGAAAGGGTCTCTTTTTTAAAG
GTCAGGGATCCATATACAGCCTTTGTTTTTCTTCTCAAGCGTTTTTCTGCTCCACGGGAGATTGCCTGTCCGGGGATTGC
CGCCACTGCGGTTATCGGCTCAGGTGTTAGCATGGGCGAAGGGGTATCAATAGGTGAGTATGTCGTTATTGGTGATGGCT
GCGTTATCGGCGACGATGTCGTTATCGGCGCGCATGGCACTTTGCTCGGTCATGTTACGATCGGAAGCGGTTCTGTCCTG
TTTCCTTCCGTTATCTGTTACGACGGAACAGTGATTGGCAAAAGGGTGACTATTCATTCCGGCAGTGTTATTGGGGCAGA
TGGCTTTGGGTTTGCTCCTCAGGCAGATGGTTCCTATATCAAAATTCCGCAAATGGGGATTGTTGAAATAGGAGATGATG
CTGAAATAGGTGCCAATGCGACGATTGACCGGGCTACAATGGGCAGCACGGTGATTGGCAAAGGGGTAAAGATTGATAAC
CTTGTTCAGATTGCTCACAATTGCCATATCGGGGATCATACCGTGATTGCTGCACAGGCTGGTATTTCCGGCAGCGTTAC
GCTTGGACGACACTGCATGATTGGTGGACAGGCCGGGTTTGCCGGCCATCTGGAGCTTGCCGACAGAACTCATGTGGCTG
CCCAGGCAGGAATTTCAAAATCATTTCTTCAGCCGGGGCAGTCTATTCGCGGTTATCCTGCGCAACCTATGCGTGAACAG
TTGAAGCAGGAGGCTTTGACTCGTGGTATCGGGACGATGAAGCAGCGAATCGATGCTCTTGAGGCGGCACTCAAGAGCTT
GCTCGATGGCTGA

Upstream 100 bases:

>100_bases
CCCACTGATAACCGCTCTGGACTTCGAATATAAGTTAAAAAAGCTAAAAATTTAACTAATTTTTTCCCCTTTCTGAAGCA
TTGTTATCATTTAATAAGAT

Downstream 100 bases:

>100_bases
GCTTTTTTCGACATCTACCCGGTCGATCAGAACCTGTTTGCCAATCATCATGATGCATGAACGGGAACAGGTCTGAATTT
CCCTCCAACCTGGGTTTCCC

Product: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTIQDIIVYLGQFFDKVVLEGSGEGAITGPAKIETARQGQVSFVSNEKYLRHLETTQASLVVVHLSLDVSAFSERVSFLK
VRDPYTAFVFLLKRFSAPREIACPGIAATAVIGSGVSMGEGVSIGEYVVIGDGCVIGDDVVIGAHGTLLGHVTIGSGSVL
FPSVICYDGTVIGKRVTIHSGSVIGADGFGFAPQADGSYIKIPQMGIVEIGDDAEIGANATIDRATMGSTVIGKGVKIDN
LVQIAHNCHIGDHTVIAAQAGISGSVTLGRHCMIGGQAGFAGHLELADRTHVAAQAGISKSFLQPGQSIRGYPAQPMREQ
LKQEALTRGIGTMKQRIDALEAALKSLLDG

Sequences:

>Translated_350_residues
MTIQDIIVYLGQFFDKVVLEGSGEGAITGPAKIETARQGQVSFVSNEKYLRHLETTQASLVVVHLSLDVSAFSERVSFLK
VRDPYTAFVFLLKRFSAPREIACPGIAATAVIGSGVSMGEGVSIGEYVVIGDGCVIGDDVVIGAHGTLLGHVTIGSGSVL
FPSVICYDGTVIGKRVTIHSGSVIGADGFGFAPQADGSYIKIPQMGIVEIGDDAEIGANATIDRATMGSTVIGKGVKIDN
LVQIAHNCHIGDHTVIAAQAGISGSVTLGRHCMIGGQAGFAGHLELADRTHVAAQAGISKSFLQPGQSIRGYPAQPMREQ
LKQEALTRGIGTMKQRIDALEAALKSLLDG
>Mature_349_residues
TIQDIIVYLGQFFDKVVLEGSGEGAITGPAKIETARQGQVSFVSNEKYLRHLETTQASLVVVHLSLDVSAFSERVSFLKV
RDPYTAFVFLLKRFSAPREIACPGIAATAVIGSGVSMGEGVSIGEYVVIGDGCVIGDDVVIGAHGTLLGHVTIGSGSVLF
PSVICYDGTVIGKRVTIHSGSVIGADGFGFAPQADGSYIKIPQMGIVEIGDDAEIGANATIDRATMGSTVIGKGVKIDNL
VQIAHNCHIGDHTVIAAQAGISGSVTLGRHCMIGGQAGFAGHLELADRTHVAAQAGISKSFLQPGQSIRGYPAQPMREQL
KQEALTRGIGTMKQRIDALEAALKSLLDG

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=323, Percent_Identity=39.938080495356, Blast_Score=220, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 36514; Mature: 36383

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQDIIVYLGQFFDKVVLEGSGEGAITGPAKIETARQGQVSFVSNEKYLRHLETTQASL
CCHHHHHHHHHHHHHHHEECCCCCCEEECCHHCCCCCCCCEEEECCHHHHHHHHCCCEEE
VVVHLSLDVSAFSERVSFLKVRDPYTAFVFLLKRFSAPREIACPGIAATAVIGSGVSMGE
EEEEEECCHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
GVSIGEYVVIGDGCVIGDDVVIGAHGTLLGHVTIGSGSVLFPSVICYDGTVIGKRVTIHS
CCCCCCEEEEECCEEECCCEEEECCCEEEEEEEECCCCCHHCEEEEECCEEECEEEEEEC
GSVIGADGFGFAPQADGSYIKIPQMGIVEIGDDAEIGANATIDRATMGSTVIGKGVKIDN
CCEECCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCEECHHHCCCHHHCCCCCHHH
LVQIAHNCHIGDHTVIAAQAGISGSVTLGRHCMIGGQAGFAGHLELADRTHVAAQAGISK
HHHHHHHCCCCCCEEEEEECCCCCCEEECCEEEEECCCCCCEEEEECCHHHHHHHHCCCH
SFLQPGQSIRGYPAQPMREQLKQEALTRGIGTMKQRIDALEAALKSLLDG
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIQDIIVYLGQFFDKVVLEGSGEGAITGPAKIETARQGQVSFVSNEKYLRHLETTQASL
CHHHHHHHHHHHHHHHEECCCCCCEEECCHHCCCCCCCCEEEECCHHHHHHHHCCCEEE
VVVHLSLDVSAFSERVSFLKVRDPYTAFVFLLKRFSAPREIACPGIAATAVIGSGVSMGE
EEEEEECCHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
GVSIGEYVVIGDGCVIGDDVVIGAHGTLLGHVTIGSGSVLFPSVICYDGTVIGKRVTIHS
CCCCCCEEEEECCEEECCCEEEECCCEEEEEEEECCCCCHHCEEEEECCEEECEEEEEEC
GSVIGADGFGFAPQADGSYIKIPQMGIVEIGDDAEIGANATIDRATMGSTVIGKGVKIDN
CCEECCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCEECHHHCCCHHHCCCCCHHH
LVQIAHNCHIGDHTVIAAQAGISGSVTLGRHCMIGGQAGFAGHLELADRTHVAAQAGISK
HHHHHHHCCCCCCEEEEEECCCCCCEEECCEEEEECCCCCCEEEEECCHHHHHHHHCCCH
SFLQPGQSIRGYPAQPMREQLKQEALTRGIGTMKQRIDALEAALKSLLDG
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA