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The map label for this gene is hdrB [H]

Identifier: 119357074

GI number: 119357074

Start: 1434061

End: 1435569

Strand: Reverse

Name: hdrB [H]

Synonym: Cpha266_1261

Alternate gene names: 119357074

Gene position: 1435569-1434061 (Counterclockwise)

Preceding gene: 119357077

Following gene: 119357073

Centisome position: 45.81

GC content: 49.3

Gene sequence:

>1509_bases
GTGCCAACAAACAAACCTGCTTTGACTGATGCGCTCAAGCATCGGATAGAAAACGCTACCGGAAACGATTACAACTGCTG
TTATCAGTGCGGCAAATGTACGGCCGGTTGTCCTGCCGGATCGTTTATGGATAACCCTCCTGCTCGCATCATGAGGCTTG
TTCAGGCAGGTTATATCGAAGAGGCGCTCAAAAGCGACGCACTCTGGTATTGTGTCGGTTGCCAGACCTGTACGGCTCGT
TGTCCGCAGAACATGGATATTGCCGCAACGATGGATGCGCTTCGAGAAATTGCTTTGAAGGAGGATATCGTTTCCCAAGA
GAGAGCCAAAAAACTGGTTACGGCTTTTCACGTCTCCTTTCTCAACAATATCCGTAAGCATGGACGTCTTCAGGAACTCT
CTCTGGTGAACAGTTACAAGCTGAGAACAAGATCTTTTCTTCAGGATGCCGGAGCCGGCGTTAAAATGATCAAAGATGGG
AAAATCAATCCGATGCATCTTTTATCAGGAAAAGAATCGATCAGCGGACGAGATCAGATTGCCGCAATTTTCAATCTTGC
TGAAAAGCCATCGGCAGCGCATGCACCTAAACGGCGACCGAAACAAAACATCGTCACCCCGAAAAAACCGCTCACGATAA
AGCCGGGAATGACTATCGGCTACTATCCCGGTTGCTCGCTAACCGGAACAGCCAAGGAGTATGACGTATCCGTAAGAAAA
ATGTGCGATCTCCTTGACATTAAACTCAAAGAAATTGAAGACTGGAACTGTTGCGGAGCGACATCTGCGCATGCAACAAA
CCACAAGTTATCCCTTCTGCTTCCCGCCCGAAATCAGGTGCTCGCCGATGCCGCAGGGCTCGACTGCGTGCTTGCCCCCT
GTGCGGCCTGCCAAAACCGCCAGGTCATCACGCGCAAGGCAATGATCGATTCGAAAGAACTTCGTGATGAAATCCGTTCG
GTAACCGGCATTGAACCCACCTGCAAATCCGAATTTATCGGAGTGACCCAACTGCTCGAAGGGTATGACGAAGAGGAGAT
CAAAAAAAGAGTAAAGCGTCCGCTCAAGAATCTCTCTCTTGCCTGCTATTACGGTTGTCTTCTGGTTCGCCCCCTTGGAG
AAATGAACTTTGACGATCCGGAAAATCCTGAAAAGATGGAAAAAATCGTTGCCGTTCTTGGTGGCAAGCCAGTCGATTGG
GCATTTAAAATAGAGTGTTGTGGCGCTGGCCTGACCCTTGCACAACAGGGACTGGTTGAAGATTTGACCCATGCAATTGC
CAAAAATGCGGCTTCGAACGGAGCTGAAGCATTTGTCGTAGCCTGTCCTCTCTGTCATGCCAATCTTGATATGCGTCAAG
AGGGAATGATGAAGCGTTATGGCGATCTTCAGCCGATGCCGGTGTATTATATTTCCGAACTGGTTTCTATCGCGCTTGGC
GCTGATCCTCAGGAAGTGGCCGTAGGCAAACATTTCGTTCCGGCTCTTGATCTGCTCTCAAAGCTTTAG

Upstream 100 bases:

>100_bases
AATAAACAAAGCAACTGGATTGGACTTTAATTTTTTTTTCTTTACAATGATACGTTTCTGTCGATTCCAATCCCGCTCCA
CGTAACGCAATATTAAGCTC

Downstream 100 bases:

>100_bases
TGGCAAGAATGACGCGTACCTACATAAACGGTATGATATGACAACGTTCGGCGTATTCTGTTGAGAACTGTTTTGTGATA
TTTTTTTAGCTGTTGCTCCC

Product: CoB--CoM heterodisulfide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MPTNKPALTDALKHRIENATGNDYNCCYQCGKCTAGCPAGSFMDNPPARIMRLVQAGYIEEALKSDALWYCVGCQTCTAR
CPQNMDIAATMDALREIALKEDIVSQERAKKLVTAFHVSFLNNIRKHGRLQELSLVNSYKLRTRSFLQDAGAGVKMIKDG
KINPMHLLSGKESISGRDQIAAIFNLAEKPSAAHAPKRRPKQNIVTPKKPLTIKPGMTIGYYPGCSLTGTAKEYDVSVRK
MCDLLDIKLKEIEDWNCCGATSAHATNHKLSLLLPARNQVLADAAGLDCVLAPCAACQNRQVITRKAMIDSKELRDEIRS
VTGIEPTCKSEFIGVTQLLEGYDEEEIKKRVKRPLKNLSLACYYGCLLVRPLGEMNFDDPENPEKMEKIVAVLGGKPVDW
AFKIECCGAGLTLAQQGLVEDLTHAIAKNAASNGAEAFVVACPLCHANLDMRQEGMMKRYGDLQPMPVYYISELVSIALG
ADPQEVAVGKHFVPALDLLSKL

Sequences:

>Translated_502_residues
MPTNKPALTDALKHRIENATGNDYNCCYQCGKCTAGCPAGSFMDNPPARIMRLVQAGYIEEALKSDALWYCVGCQTCTAR
CPQNMDIAATMDALREIALKEDIVSQERAKKLVTAFHVSFLNNIRKHGRLQELSLVNSYKLRTRSFLQDAGAGVKMIKDG
KINPMHLLSGKESISGRDQIAAIFNLAEKPSAAHAPKRRPKQNIVTPKKPLTIKPGMTIGYYPGCSLTGTAKEYDVSVRK
MCDLLDIKLKEIEDWNCCGATSAHATNHKLSLLLPARNQVLADAAGLDCVLAPCAACQNRQVITRKAMIDSKELRDEIRS
VTGIEPTCKSEFIGVTQLLEGYDEEEIKKRVKRPLKNLSLACYYGCLLVRPLGEMNFDDPENPEKMEKIVAVLGGKPVDW
AFKIECCGAGLTLAQQGLVEDLTHAIAKNAASNGAEAFVVACPLCHANLDMRQEGMMKRYGDLQPMPVYYISELVSIALG
ADPQEVAVGKHFVPALDLLSKL
>Mature_501_residues
PTNKPALTDALKHRIENATGNDYNCCYQCGKCTAGCPAGSFMDNPPARIMRLVQAGYIEEALKSDALWYCVGCQTCTARC
PQNMDIAATMDALREIALKEDIVSQERAKKLVTAFHVSFLNNIRKHGRLQELSLVNSYKLRTRSFLQDAGAGVKMIKDGK
INPMHLLSGKESISGRDQIAAIFNLAEKPSAAHAPKRRPKQNIVTPKKPLTIKPGMTIGYYPGCSLTGTAKEYDVSVRKM
CDLLDIKLKEIEDWNCCGATSAHATNHKLSLLLPARNQVLADAAGLDCVLAPCAACQNRQVITRKAMIDSKELRDEIRSV
TGIEPTCKSEFIGVTQLLEGYDEEEIKKRVKRPLKNLSLACYYGCLLVRPLGEMNFDDPENPEKMEKIVAVLGGKPVDWA
FKIECCGAGLTLAQQGLVEDLTHAIAKNAASNGAEAFVVACPLCHANLDMRQEGMMKRYGDLQPMPVYYISELVSIALGA
DPQEVAVGKHFVPALDLLSKL

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction [H]

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017678
- InterPro:   IPR004017 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 55049; Mature: 54917

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNKPALTDALKHRIENATGNDYNCCYQCGKCTAGCPAGSFMDNPPARIMRLVQAGYIE
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
EALKSDALWYCVGCQTCTARCPQNMDIAATMDALREIALKEDIVSQERAKKLVTAFHVSF
HHHHCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNNIRKHGRLQELSLVNSYKLRTRSFLQDAGAGVKMIKDGKINPMHLLSGKESISGRDQI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCHHHH
AAIFNLAEKPSAAHAPKRRPKQNIVTPKKPLTIKPGMTIGYYPGCSLTGTAKEYDVSVRK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHH
MCDLLDIKLKEIEDWNCCGATSAHATNHKLSLLLPARNQVLADAAGLDCVLAPCAACQNR
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHCCCC
QVITRKAMIDSKELRDEIRSVTGIEPTCKSEFIGVTQLLEGYDEEEIKKRVKRPLKNLSL
CHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHH
ACYYGCLLVRPLGEMNFDDPENPEKMEKIVAVLGGKPVDWAFKIECCGAGLTLAQQGLVE
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHH
DLTHAIAKNAASNGAEAFVVACPLCHANLDMRQEGMMKRYGDLQPMPVYYISELVSIALG
HHHHHHHHHHCCCCCCEEEEECCHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
ADPQEVAVGKHFVPALDLLSKL
CCHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure 
PTNKPALTDALKHRIENATGNDYNCCYQCGKCTAGCPAGSFMDNPPARIMRLVQAGYIE
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
EALKSDALWYCVGCQTCTARCPQNMDIAATMDALREIALKEDIVSQERAKKLVTAFHVSF
HHHHCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNNIRKHGRLQELSLVNSYKLRTRSFLQDAGAGVKMIKDGKINPMHLLSGKESISGRDQI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCHHHH
AAIFNLAEKPSAAHAPKRRPKQNIVTPKKPLTIKPGMTIGYYPGCSLTGTAKEYDVSVRK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHH
MCDLLDIKLKEIEDWNCCGATSAHATNHKLSLLLPARNQVLADAAGLDCVLAPCAACQNR
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHCCCC
QVITRKAMIDSKELRDEIRSVTGIEPTCKSEFIGVTQLLEGYDEEEIKKRVKRPLKNLSL
CHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHH
ACYYGCLLVRPLGEMNFDDPENPEKMEKIVAVLGGKPVDWAFKIECCGAGLTLAQQGLVE
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHH
DLTHAIAKNAASNGAEAFVVACPLCHANLDMRQEGMMKRYGDLQPMPVYYISELVSIALG
HHHHHHHHHHCCCCCCEEEEECCHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
ADPQEVAVGKHFVPALDLLSKL
CCHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]