| Definition | Chlorobium phaeobacteroides DSM 266 chromosome, complete genome. |
|---|---|
| Accession | NC_008639 |
| Length | 3,133,902 |
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The map label for this gene is mutB [H]
Identifier: 119356981
GI number: 119356981
Start: 1310741
End: 1312882
Strand: Reverse
Name: mutB [H]
Synonym: Cpha266_1164
Alternate gene names: 119356981
Gene position: 1312882-1310741 (Counterclockwise)
Preceding gene: 119356982
Following gene: 119356980
Centisome position: 41.89
GC content: 51.77
Gene sequence:
>2142_bases ATGAGACCGGATTTTTCAGGCATCGATATCTTTTCCGCCTTTTCAGCCAATAAGGATAATCCCATAGAAGTGCCCCGGCA CTTCACCTCCGCTGAGGGAATCGACATACAATCCTTTTACCCCGGGCACAATAGCGAGTCCTCCGCAATAACGCATTTTG CGCCGGGATTTCCCCCCTTCAACGGAGGCCCCTACTCAACAATGTACACCTCGCGGCCATGGACTATCCGCCAGTATGCC GGATTTTCAACCGCTGAAGAGTCAAACCGGTTTTACCGCCAGAACCTTGCGGCTGGCCAGAAAGGCCTTTCGGTTGCCTT TGACCTCCCGACGCACCGAGGTTATGATTCCGATCATGAACGGGTTATCGGAGATGTCGGCAAAGCCGGCGTTGCAATCG ACACGGTCGAGGATATGAAAATCCTCTTCGACAGCATCCCGCTTGACGACATATCGGTATCGATGACCATGAACGGCGCC GTTCTTCCTGTTATGGCATTTTATATCGTTGCCGCCGAAGAGCAGGGCGTTCCGCCTGAAAAGCTGAGCGGCACCATTCA GAACGACATTCTCAAAGAGTTCATGGTGCGCAATACCTATATCTACCCGCCTGAACCATCCATGCGAATTATTGCCGACA TATTTCAATACACAAGCCGCAGGATGCCGAAATTCAACTCGATCAGCATTTCAGGATACCATATGCAGGAGGCTGGAGCG ACGGCTGATCTTGAACTTGCTTACACGCTGGCCGACGGACTTGAGTATATCCGTACCGGCCTCAAGGCAGGGCTTGATAT TGATGCCTTTGCGCCAAGACTCTCCTTTTTCTGGGGCATAGGGATGAACTACTTCATGGAGATAGCCAAGCTGCGTGCCG CAAGAATGCTCTGGGCTAAAATTGTCCGGACGTTCAATCCGAAAAACAAGAAATCACTGATGCTTCGATCCCACTGCCAG ACCTCAGGATGGAGTCTCACCGCACAGGATCCATTCAACAACATCACAAGAACCTGTCTTGAAGCCCTTGCCGCATCGCT CGGTCACACCCAGTCGCTGCACACCAATGCGCTCGACGAAGCAATAGCGCTTCCCTCCCCTTTTTCAGCCCGCATTGCCA GAAACACCCAACTCTTCCTTCAGGAAGAGACCGATATCACCCGAAGCATCGATCCCTGGGCAGGCTCATTTTATGTGGAA AATCTGACGGCGAAACTTGCTGAAAAAGCATGGAACATCATCACTGCCATCGAAGAGGCCGGCGGAATGGTAAAAGCCAT TGAACGAGGCATTCCTCAACTGCAGATTGAAGAGGCTGCCACCAGAAAACAGGCCCGTATCGATAGCGGCGAAGACATGA TCATCGGAGTTAACGGTTTCACGACTGCAAGTACGACTGAAATCGACCTGCTTGAGGTCGACAATACCATGGTACTCCGC CAGCAGCTTGACCGCCTTAAAACCGTCAAGGCGCGACGTCATGAAGAAGAGACAGCCCAAGCCCTGCTGGCCATTGAGCA GTGTGCGGCCTCAGGCAAAGGGAATCTGCTTGAACTTGCCGTTGACGCAGCAAGAAAACGAGCCACATTGGGTGAAATAT GCATGGCATGTGAAAATATTTACGGAAGATATCGTGCCCGAACAAAGCTCAACACCACCGTCTATATGTCTGAAATGCAG AATAACACGCTCTTCAGGGAGGCGCAGCAACTTGCCGATACCTTTGCATCCCTCGAAGGAAGACGGCCGAGAATCATGGT AGCGAAAGTAGGCCAGGACGGTCACGACCGCGGGGCAAAGGTTATTGCGGCGGGATTTGCCGATATTGGCTTTGACGTTG ATATCAGCCCGCTTTTTCAGACACCTGAAGAGATCGTCAGCCAGGCGCTTGACAATGATGTCCACCTTATCGGAATATCC AGTCTTGCCGGAGGACATAAAACCCTTATCCCGAAAATCATCGAGACGCTTCACCTGCAGGATAGAAAAGACATCCTTGT CGTTGTCGGGGGAATCATTCCCGACAACGATCACGCGTTTCTGTACGAGCAGGGTGTTGCGGGAATTTTCGGCCCGGGAA CGGTCATTTCCGAAGCGGCGATCAAACTGCTCAACCTTTTGATGGCAAAGTTTTCGACATGA
Upstream 100 bases:
>100_bases ATCCGGAACCGCTTTTCCGTGCCGGCATAGACAGCTTTATTCATACAGGAGTAAACATCATCGACCATTTGACCATGTAC CAACATAAAACCGGAGTACA
Downstream 100 bases:
>100_bases AAAGCGCAGAAAAAATCAGCTCTGATGGCAATAACCAGGAACCGGACGTTGAGAAAATGGTCTGCGGGATCATGAACGGC AACCGGCAGATGCTTGCCCG
Product: methylmalonyl-CoA mutase
Products: NA
Alternate protein names: MCM-alpha [H]
Number of amino acids: Translated: 713; Mature: 713
Protein sequence:
>713_residues MRPDFSGIDIFSAFSANKDNPIEVPRHFTSAEGIDIQSFYPGHNSESSAITHFAPGFPPFNGGPYSTMYTSRPWTIRQYA GFSTAEESNRFYRQNLAAGQKGLSVAFDLPTHRGYDSDHERVIGDVGKAGVAIDTVEDMKILFDSIPLDDISVSMTMNGA VLPVMAFYIVAAEEQGVPPEKLSGTIQNDILKEFMVRNTYIYPPEPSMRIIADIFQYTSRRMPKFNSISISGYHMQEAGA TADLELAYTLADGLEYIRTGLKAGLDIDAFAPRLSFFWGIGMNYFMEIAKLRAARMLWAKIVRTFNPKNKKSLMLRSHCQ TSGWSLTAQDPFNNITRTCLEALAASLGHTQSLHTNALDEAIALPSPFSARIARNTQLFLQEETDITRSIDPWAGSFYVE NLTAKLAEKAWNIITAIEEAGGMVKAIERGIPQLQIEEAATRKQARIDSGEDMIIGVNGFTTASTTEIDLLEVDNTMVLR QQLDRLKTVKARRHEEETAQALLAIEQCAASGKGNLLELAVDAARKRATLGEICMACENIYGRYRARTKLNTTVYMSEMQ NNTLFREAQQLADTFASLEGRRPRIMVAKVGQDGHDRGAKVIAAGFADIGFDVDISPLFQTPEEIVSQALDNDVHLIGIS SLAGGHKTLIPKIIETLHLQDRKDILVVVGGIIPDNDHAFLYEQGVAGIFGPGTVISEAAIKLLNLLMAKFST
Sequences:
>Translated_713_residues MRPDFSGIDIFSAFSANKDNPIEVPRHFTSAEGIDIQSFYPGHNSESSAITHFAPGFPPFNGGPYSTMYTSRPWTIRQYA GFSTAEESNRFYRQNLAAGQKGLSVAFDLPTHRGYDSDHERVIGDVGKAGVAIDTVEDMKILFDSIPLDDISVSMTMNGA VLPVMAFYIVAAEEQGVPPEKLSGTIQNDILKEFMVRNTYIYPPEPSMRIIADIFQYTSRRMPKFNSISISGYHMQEAGA TADLELAYTLADGLEYIRTGLKAGLDIDAFAPRLSFFWGIGMNYFMEIAKLRAARMLWAKIVRTFNPKNKKSLMLRSHCQ TSGWSLTAQDPFNNITRTCLEALAASLGHTQSLHTNALDEAIALPSPFSARIARNTQLFLQEETDITRSIDPWAGSFYVE NLTAKLAEKAWNIITAIEEAGGMVKAIERGIPQLQIEEAATRKQARIDSGEDMIIGVNGFTTASTTEIDLLEVDNTMVLR QQLDRLKTVKARRHEEETAQALLAIEQCAASGKGNLLELAVDAARKRATLGEICMACENIYGRYRARTKLNTTVYMSEMQ NNTLFREAQQLADTFASLEGRRPRIMVAKVGQDGHDRGAKVIAAGFADIGFDVDISPLFQTPEEIVSQALDNDVHLIGIS SLAGGHKTLIPKIIETLHLQDRKDILVVVGGIIPDNDHAFLYEQGVAGIFGPGTVISEAAIKLLNLLMAKFST >Mature_713_residues MRPDFSGIDIFSAFSANKDNPIEVPRHFTSAEGIDIQSFYPGHNSESSAITHFAPGFPPFNGGPYSTMYTSRPWTIRQYA GFSTAEESNRFYRQNLAAGQKGLSVAFDLPTHRGYDSDHERVIGDVGKAGVAIDTVEDMKILFDSIPLDDISVSMTMNGA VLPVMAFYIVAAEEQGVPPEKLSGTIQNDILKEFMVRNTYIYPPEPSMRIIADIFQYTSRRMPKFNSISISGYHMQEAGA TADLELAYTLADGLEYIRTGLKAGLDIDAFAPRLSFFWGIGMNYFMEIAKLRAARMLWAKIVRTFNPKNKKSLMLRSHCQ TSGWSLTAQDPFNNITRTCLEALAASLGHTQSLHTNALDEAIALPSPFSARIARNTQLFLQEETDITRSIDPWAGSFYVE NLTAKLAEKAWNIITAIEEAGGMVKAIERGIPQLQIEEAATRKQARIDSGEDMIIGVNGFTTASTTEIDLLEVDNTMVLR QQLDRLKTVKARRHEEETAQALLAIEQCAASGKGNLLELAVDAARKRATLGEICMACENIYGRYRARTKLNTTVYMSEMQ NNTLFREAQQLADTFASLEGRRPRIMVAKVGQDGHDRGAKVIAAGFADIGFDVDISPLFQTPEEIVSQALDNDVHLIGIS SLAGGHKTLIPKIIETLHLQDRKDILVVVGGIIPDNDHAFLYEQGVAGIFGPGTVISEAAIKLLNLLMAKFST
Specific function: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates [H]
COG id: COG1884
COG function: function code I; Methylmalonyl-CoA mutase, N-terminal domain/subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 B12-binding domain [H]
Homologues:
Organism=Homo sapiens, GI156105689, Length=687, Percent_Identity=61.1353711790393, Blast_Score=882, Evalue=0.0, Organism=Escherichia coli, GI1789284, Length=682, Percent_Identity=59.8240469208211, Blast_Score=818, Evalue=0.0, Organism=Caenorhabditis elegans, GI25144500, Length=686, Percent_Identity=59.7667638483965, Blast_Score=845, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006159 - InterPro: IPR016176 - InterPro: IPR014348 - InterPro: IPR006158 - InterPro: IPR006099 - InterPro: IPR006098 [H]
Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]
EC number: =5.4.99.2 [H]
Molecular weight: Translated: 78619; Mature: 78619
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: PS00544 METMALONYL_COA_MUTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRPDFSGIDIFSAFSANKDNPIEVPRHFTSAEGIDIQSFYPGHNSESSAITHFAPGFPPF CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCC NGGPYSTMYTSRPWTIRQYAGFSTAEESNRFYRQNLAAGQKGLSVAFDLPTHRGYDSDHE CCCCCCCEECCCCEEEHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHH RVIGDVGKAGVAIDTVEDMKILFDSIPLDDISVSMTMNGAVLPVMAFYIVAAEEQGVPPE HHHHHCCCCCEEEECHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHH KLSGTIQNDILKEFMVRNTYIYPPEPSMRIIADIFQYTSRRMPKFNSISISGYHMQEAGA HHCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECEEECCCCC TADLELAYTLADGLEYIRTGLKAGLDIDAFAPRLSFFWGIGMNYFMEIAKLRAARMLWAK CCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH IVRTFNPKNKKSLMLRSHCQTSGWSLTAQDPFNNITRTCLEALAASLGHTQSLHTNALDE HHHHCCCCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH AIALPSPFSARIARNTQLFLQEETDITRSIDPWAGSFYVENLTAKLAEKAWNIITAIEEA HHCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH GGMVKAIERGIPQLQIEEAATRKQARIDSGEDMIIGVNGFTTASTTEIDLLEVDNTMVLR CCHHHHHHCCCCCEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHHH QQLDRLKTVKARRHEEETAQALLAIEQCAASGKGNLLELAVDAARKRATLGEICMACENI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH YGRYRARTKLNTTVYMSEMQNNTLFREAQQLADTFASLEGRRPRIMVAKVGQDGHDRGAK HHHHHHCEECCCEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCE VIAAGFADIGFDVDISPLFQTPEEIVSQALDNDVHLIGISSLAGGHKTLIPKIIETLHLQ EEEECHHHCCCCCCCHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCC DRKDILVVVGGIIPDNDHAFLYEQGVAGIFGPGTVISEAAIKLLNLLMAKFST CCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MRPDFSGIDIFSAFSANKDNPIEVPRHFTSAEGIDIQSFYPGHNSESSAITHFAPGFPPF CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCC NGGPYSTMYTSRPWTIRQYAGFSTAEESNRFYRQNLAAGQKGLSVAFDLPTHRGYDSDHE CCCCCCCEECCCCEEEHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHH RVIGDVGKAGVAIDTVEDMKILFDSIPLDDISVSMTMNGAVLPVMAFYIVAAEEQGVPPE HHHHHCCCCCEEEECHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHH KLSGTIQNDILKEFMVRNTYIYPPEPSMRIIADIFQYTSRRMPKFNSISISGYHMQEAGA HHCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECEEECCCCC TADLELAYTLADGLEYIRTGLKAGLDIDAFAPRLSFFWGIGMNYFMEIAKLRAARMLWAK CCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH IVRTFNPKNKKSLMLRSHCQTSGWSLTAQDPFNNITRTCLEALAASLGHTQSLHTNALDE HHHHCCCCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH AIALPSPFSARIARNTQLFLQEETDITRSIDPWAGSFYVENLTAKLAEKAWNIITAIEEA HHCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH GGMVKAIERGIPQLQIEEAATRKQARIDSGEDMIIGVNGFTTASTTEIDLLEVDNTMVLR CCHHHHHHCCCCCEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHHH QQLDRLKTVKARRHEEETAQALLAIEQCAASGKGNLLELAVDAARKRATLGEICMACENI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH YGRYRARTKLNTTVYMSEMQNNTLFREAQQLADTFASLEGRRPRIMVAKVGQDGHDRGAK HHHHHHCEECCCEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCE VIAAGFADIGFDVDISPLFQTPEEIVSQALDNDVHLIGISSLAGGHKTLIPKIIETLHLQ EEEECHHHCCCCCCCHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCC DRKDILVVVGGIIPDNDHAFLYEQGVAGIFGPGTVISEAAIKLLNLLMAKFST CCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8566763; 12949112 [H]