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The map label for this gene is aroB [H]

Identifier: 119356667

GI number: 119356667

Start: 949749

End: 950846

Strand: Reverse

Name: aroB [H]

Synonym: Cpha266_0836

Alternate gene names: 119356667

Gene position: 950846-949749 (Counterclockwise)

Preceding gene: 119356668

Following gene: 119356664

Centisome position: 30.34

GC content: 50.09

Gene sequence:

>1098_bases
GTGAACACCATCATAGTCAAGACACCGGTCACCCGACATCTCGGAGAGCTCTTCAGCAAAAACGGTCTTTCAAAAAAAAC
CGTCGTGCTGTTTGATGAAAACACCCGTAATCTTTTCGGCTCCGAGCTGCTCGACCTCCTCACCGAACAAGGTTTTCAAT
GGCTTGATCTGGTAGTTCCTGCAAAGGAAACATCCAAGAGTTTCAATACCGCCAACAAGCTCTACGGAAAGATGATCCTG
GCCGATGTCGACCGTAGCTGGAACCTGCTTGCCGTTGGAGGAGGCGTTGTCGGAGACCTCGGCGGATTTATCGCCGCAAG
CTACTATAGAGGCATTCCGATCATCCAGCTCCCAACCACCCTTCTGGCAATGACCGACAGCTCGATAGGAGGCAAGGTTG
CCATCAATCATCCGCTCGGCAAAAACCTGATCGGTTTTTTCCATCTGCCGAGACTTGTCCTGATCGACCCGGCATATCTT
AAAACGCTTCCCATGCGGGAAATTCATGCAGGCATGGCCGAAGTAGTCAAGTACGGATTTATTGCCGATCGCGACTTCCT
CTTCCGGCTTGACCGTCACTTCAGCGAGATTATTGCACTCGAAGAGCCGTTTGTTACCGATGCGATACGACGAAGCGCCG
AAATCAAATCAGATGTTGTTGAAAAGGATTTTCGGGAAGAAAGCGGACTCAGGGCAACCCTTAATTTCGGCCACACCTTT
GCCCACGGACTGGAAAAACTTGCTGACTACCGATACCTCCGCCATGGCGAAGCTGTGACAATAGGCATGGTTTGCGCACT
CTCCCTGTCGCACGGCCTCGGCTATCTTAATAGGGAAGAACTGGATCAGGGAGTACGCATTCTCCGGAAGTTCCGGTTTC
CACACGGGCTTGTACAGCGAAGATTTCTCGGAGAAAGCAGTGAATCACTTCTTGAATATATGCTGTCAGACAAAAAAAAG
CTTGACAGAAAACTCCGGTTTGTCCTGCTGAAAAGTCTCGGGTCGGCATTTCTGCTTGAAGAAACCGTTGAAGACCACCA
TGTTCTCAAAGCAATAACGGAGGCAAAGGAGCTCTTCAAAAAAGCGTTGGCCTGTTAA

Upstream 100 bases:

>100_bases
ATAGGTTCAACGGTCGAAGAACTTACCCGAAAAATAAACCGGTATGTAAGAAAAACAACCGGAAATTCAAGGGCGAAATA
AACCCAAAGCAACGTTATTC

Downstream 100 bases:

>100_bases
GCCTGAAGAGATATCCTGCGCCCCTGATCACGGCATATTCGTCATGCAGCGTCAGCGAATCGAGCAATCCTGCAATCAGG
GGTGCGCTTCCTCCGGTTGC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNTIIVKTPVTRHLGELFSKNGLSKKTVVLFDENTRNLFGSELLDLLTEQGFQWLDLVVPAKETSKSFNTANKLYGKMIL
ADVDRSWNLLAVGGGVVGDLGGFIAASYYRGIPIIQLPTTLLAMTDSSIGGKVAINHPLGKNLIGFFHLPRLVLIDPAYL
KTLPMREIHAGMAEVVKYGFIADRDFLFRLDRHFSEIIALEEPFVTDAIRRSAEIKSDVVEKDFREESGLRATLNFGHTF
AHGLEKLADYRYLRHGEAVTIGMVCALSLSHGLGYLNREELDQGVRILRKFRFPHGLVQRRFLGESSESLLEYMLSDKKK
LDRKLRFVLLKSLGSAFLLEETVEDHHVLKAITEAKELFKKALAC

Sequences:

>Translated_365_residues
MNTIIVKTPVTRHLGELFSKNGLSKKTVVLFDENTRNLFGSELLDLLTEQGFQWLDLVVPAKETSKSFNTANKLYGKMIL
ADVDRSWNLLAVGGGVVGDLGGFIAASYYRGIPIIQLPTTLLAMTDSSIGGKVAINHPLGKNLIGFFHLPRLVLIDPAYL
KTLPMREIHAGMAEVVKYGFIADRDFLFRLDRHFSEIIALEEPFVTDAIRRSAEIKSDVVEKDFREESGLRATLNFGHTF
AHGLEKLADYRYLRHGEAVTIGMVCALSLSHGLGYLNREELDQGVRILRKFRFPHGLVQRRFLGESSESLLEYMLSDKKK
LDRKLRFVLLKSLGSAFLLEETVEDHHVLKAITEAKELFKKALAC
>Mature_365_residues
MNTIIVKTPVTRHLGELFSKNGLSKKTVVLFDENTRNLFGSELLDLLTEQGFQWLDLVVPAKETSKSFNTANKLYGKMIL
ADVDRSWNLLAVGGGVVGDLGGFIAASYYRGIPIIQLPTTLLAMTDSSIGGKVAINHPLGKNLIGFFHLPRLVLIDPAYL
KTLPMREIHAGMAEVVKYGFIADRDFLFRLDRHFSEIIALEEPFVTDAIRRSAEIKSDVVEKDFREESGLRATLNFGHTF
AHGLEKLADYRYLRHGEAVTIGMVCALSLSHGLGYLNREELDQGVRILRKFRFPHGLVQRRFLGESSESLLEYMLSDKKK
LDRKLRFVLLKSLGSAFLLEETVEDHHVLKAITEAKELFKKALAC

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=332, Percent_Identity=38.5542168674699, Blast_Score=210, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320332, Length=362, Percent_Identity=35.0828729281768, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 41021; Mature: 41021

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIIVKTPVTRHLGELFSKNGLSKKTVVLFDENTRNLFGSELLDLLTEQGFQWLDLVVP
CCEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEC
AKETSKSFNTANKLYGKMILADVDRSWNLLAVGGGVVGDLGGFIAASYYRGIPIIQLPTT
CHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEECCHH
LLAMTDSSIGGKVAINHPLGKNLIGFFHLPRLVLIDPAYLKTLPMREIHAGMAEVVKYGF
HHHCCCCCCCCEEEECCCCCCHHHHHHHCCHHEEECHHHHHHCCHHHHHHHHHHHHHHCC
IADRDFLFRLDRHFSEIIALEEPFVTDAIRRSAEIKSDVVEKDFREESGLRATLNFGHTF
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
AHGLEKLADYRYLRHGEAVTIGMVCALSLSHGLGYLNREELDQGVRILRKFRFPHGLVQR
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
RFLGESSESLLEYMLSDKKKLDRKLRFVLLKSLGSAFLLEETVEDHHVLKAITEAKELFK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KALAC
HHHCC
>Mature Secondary Structure
MNTIIVKTPVTRHLGELFSKNGLSKKTVVLFDENTRNLFGSELLDLLTEQGFQWLDLVVP
CCEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEC
AKETSKSFNTANKLYGKMILADVDRSWNLLAVGGGVVGDLGGFIAASYYRGIPIIQLPTT
CHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEECCHH
LLAMTDSSIGGKVAINHPLGKNLIGFFHLPRLVLIDPAYLKTLPMREIHAGMAEVVKYGF
HHHCCCCCCCCEEEECCCCCCHHHHHHHCCHHEEECHHHHHHCCHHHHHHHHHHHHHHCC
IADRDFLFRLDRHFSEIIALEEPFVTDAIRRSAEIKSDVVEKDFREESGLRATLNFGHTF
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
AHGLEKLADYRYLRHGEAVTIGMVCALSLSHGLGYLNREELDQGVRILRKFRFPHGLVQR
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
RFLGESSESLLEYMLSDKKKLDRKLRFVLLKSLGSAFLLEETVEDHHVLKAITEAKELFK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KALAC
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA