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The map label for this gene is moeZ [H]

Identifier: 119356562

GI number: 119356562

Start: 829543

End: 830286

Strand: Reverse

Name: moeZ [H]

Synonym: Cpha266_0728

Alternate gene names: 119356562

Gene position: 830286-829543 (Counterclockwise)

Preceding gene: 119356563

Following gene: 119356561

Centisome position: 26.49

GC content: 49.6

Gene sequence:

>744_bases
ATGATATTGACTGACGATCAACAACAGCGCTACTCGCGTCATCTCTCTCTTCCGGAAATCGGCGAAAAAGGACAAAAAAA
ACTGCTTCGCTCAAAGGTACTTGTTGTTGGCGCAGGAGGACTCGGATCCCCTGCCGCATTTTTTCTTGCAGCAGCGGGAA
TCGGCACAATCGGGCTTATCGATGGAGATACCGTAACCTTAAGCAATCTCCAACGTCAGATTCTTCATACCACCGCATCA
ATCGGACAACTGAAAGTCCGCTCAGCCGAAACAAGACTTCTTGCCCTTAATCCTGACATCAAATGTGAACTCTACCCGTT
CAGGCTTACCACAGAAAACGCACCGGAAATTCTTGCTGATTATGACTTTGTTCTTGATGCCACTGATAATTTTGATTCGA
AATTTTTGATAGCAAGAGCATGTCACCATGCATCCACATCATACTCTCATGCCGGCATCAGTGCGTTTTATGGACAGACC
TTGACCGTCAAGCCAGGACAATCCGCCTGCTTCAGATGCATATTTCATGAACAGAAAATCCATCCGGAGGGAATTCCCGC
AGGCCCTCTCGGCGCTCTGCCGGGCGTAATCGGTTCCATACAGGCCACTGAGGCCATCAAAGTCCTGCTCTCCATCGGCA
CACCGCTCTACAATACGGTCATGAGCTACAATGCGCTTTCCATGGAAATCAGAAAGATTCCCGTTCAGCGCGACCCGCAC
TGCCCCCTCTGTGGAACGGCGTAA

Upstream 100 bases:

>100_bases
CAGCCAAAGAGTTCTGCAACGCCCTGCAAAAACAAAACATCGAACCGGTTTTCAAAAACTGGGAGCCGGTTTATAACGGC
CCGTCATCTGCTGCATCGGC

Downstream 100 bases:

>100_bases
CACCGATCCTTTACGTTGCAGCAACATCCCCTGAGAATGAATCATGATCTCCTTTTTGCTGTTGCCAAATTCAATCGGCT
CCGAACAGCCCCGTTATCTG

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MILTDDQQQRYSRHLSLPEIGEKGQKKLLRSKVLVVGAGGLGSPAAFFLAAAGIGTIGLIDGDTVTLSNLQRQILHTTAS
IGQLKVRSAETRLLALNPDIKCELYPFRLTTENAPEILADYDFVLDATDNFDSKFLIARACHHASTSYSHAGISAFYGQT
LTVKPGQSACFRCIFHEQKIHPEGIPAGPLGALPGVIGSIQATEAIKVLLSIGTPLYNTVMSYNALSMEIRKIPVQRDPH
CPLCGTA

Sequences:

>Translated_247_residues
MILTDDQQQRYSRHLSLPEIGEKGQKKLLRSKVLVVGAGGLGSPAAFFLAAAGIGTIGLIDGDTVTLSNLQRQILHTTAS
IGQLKVRSAETRLLALNPDIKCELYPFRLTTENAPEILADYDFVLDATDNFDSKFLIARACHHASTSYSHAGISAFYGQT
LTVKPGQSACFRCIFHEQKIHPEGIPAGPLGALPGVIGSIQATEAIKVLLSIGTPLYNTVMSYNALSMEIRKIPVQRDPH
CPLCGTA
>Mature_247_residues
MILTDDQQQRYSRHLSLPEIGEKGQKKLLRSKVLVVGAGGLGSPAAFFLAAAGIGTIGLIDGDTVTLSNLQRQILHTTAS
IGQLKVRSAETRLLALNPDIKCELYPFRLTTENAPEILADYDFVLDATDNFDSKFLIARACHHASTSYSHAGISAFYGQT
LTVKPGQSACFRCIFHEQKIHPEGIPAGPLGALPGVIGSIQATEAIKVLLSIGTPLYNTVMSYNALSMEIRKIPVQRDPH
CPLCGTA

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=233, Percent_Identity=38.1974248927039, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI13376212, Length=254, Percent_Identity=29.9212598425197, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI38327032, Length=218, Percent_Identity=28.8990825688073, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4885649, Length=145, Percent_Identity=31.7241379310345, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI38045948, Length=165, Percent_Identity=29.6969696969697, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=37.9032258064516, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI87082356, Length=246, Percent_Identity=41.4634146341463, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789177, Length=144, Percent_Identity=31.25, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17540406, Length=242, Percent_Identity=34.297520661157, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17508819, Length=253, Percent_Identity=25.6916996047431, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203301, Length=159, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321903, Length=218, Percent_Identity=38.0733944954128, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320598, Length=180, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322639, Length=173, Percent_Identity=28.9017341040462, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=247, Percent_Identity=40.8906882591093, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=36, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641311, Length=254, Percent_Identity=30.7086614173228, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26600; Mature: 26600

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTDDQQQRYSRHLSLPEIGEKGQKKLLRSKVLVVGAGGLGSPAAFFLAAAGIGTIGLI
CCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHCCCEEEEE
DGDTVTLSNLQRQILHTTASIGQLKVRSAETRLLALNPDIKCELYPFRLTTENAPEILAD
CCCEEEHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCEEEEEEEEEECCCCCHHHHC
YDFVLDATDNFDSKFLIARACHHASTSYSHAGISAFYGQTLTVKPGQSACFRCIFHEQKI
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHCCC
HPEGIPAGPLGALPGVIGSIQATEAIKVLLSIGTPLYNTVMSYNALSMEIRKIPVQRDPH
CCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHCCHHEEEEEECCCCCCCC
CPLCGTA
CCCCCCC
>Mature Secondary Structure
MILTDDQQQRYSRHLSLPEIGEKGQKKLLRSKVLVVGAGGLGSPAAFFLAAAGIGTIGLI
CCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHCCCEEEEE
DGDTVTLSNLQRQILHTTASIGQLKVRSAETRLLALNPDIKCELYPFRLTTENAPEILAD
CCCEEEHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCEEEEEEEEEECCCCCHHHHC
YDFVLDATDNFDSKFLIARACHHASTSYSHAGISAFYGQTLTVKPGQSACFRCIFHEQKI
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHCCC
HPEGIPAGPLGALPGVIGSIQATEAIKVLLSIGTPLYNTVMSYNALSMEIRKIPVQRDPH
CCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHCCHHEEEEEECCCCCCCC
CPLCGTA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]