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The map label for this gene is hypB [H]

Identifier: 119356555

GI number: 119356555

Start: 822088

End: 822900

Strand: Direct

Name: hypB [H]

Synonym: Cpha266_0721

Alternate gene names: 119356555

Gene position: 822088-822900 (Clockwise)

Preceding gene: 119356554

Following gene: 119356556

Centisome position: 26.23

GC content: 48.22

Gene sequence:

>813_bases
ATGTGTGATACCTGTGGTTGCTCAACGGACGGAGGAGCGCTGCTTCGCAAGCCGGGAGACAGCGATTACCATGTTCATAT
AGGCGATGAAGGGCATGGCCATGAGCACGGTCATGATCATGACCATGATCGCCATCACCACGACCATCAGGCTGGTCGCA
GTCGGAAAATTGAGGTTGAACAGGATGTTCTGTTGAAAAACAATCTCCTTGCCGAGAGAAATCGGGGTTATTTTGAGGCA
AGAAATATTCTTGCACTTAATTTTCTCAGTTCACCCGGTTCCGGTAAAACATCACTGCTTGAAAAGATCATACCCATGTT
TCGCCTCAAGCATCCGGTTGCGGTTATCGAGGGTGATCAACAGACGACCAACGATGCCGATCGTATTCATGCTCTTGGCG
TTGAGGTGATTCAGGTGAACACAGGGACGGGATGCCATCTCGATGCGCTTATGATCAATCGTGCAGTCAAAGAGCTGAAT
CTTCAGAATAATTCGTTGTTGTGTATCGAAAATGTAGGCAATCTTGTCTGTCCGGCGATGTTCGATCTCGGCGAGGCGTG
CAAGGTTGTGGTGATCAGTGTGACGGAGGGCGATGATAAACCGCTGAAATATCCCAATATGTTTCATGAGGCGGATGTTT
GCGTGCTCAACAAGACCGATCTGCTTGACTATGTTGATTTTGATTCTGCGCAATGCAAAAAGAACGCACTTTCGATCAAT
CACCACCTTGAATGGTTTGAGGTTTCGGCCAAGACCGGAGAGGGTCTCGAACTCTTGATGCAATGGCTCGAAAACAGAAT
GGAACAGAGCTGA

Upstream 100 bases:

>100_bases
ATGCGGAGTGCCCGGTTTGCCGTTCACTGAAAGTTCGCATTGTTTCGGGAGAAGAGTTCATGATTCAGTCAATTATTATC
GAAGAGGGAGAATAATAACT

Downstream 100 bases:

>100_bases
ACGTCGAGCCGGGAATCGGTGAAGTTCGCCGGGGTATTCTTGTTCACGGAATTGTTCAAGGGGTGGGGTTTCGTCCTTTT
GTGTACCGTACGGCTAAAGC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MCDTCGCSTDGGALLRKPGDSDYHVHIGDEGHGHEHGHDHDHDRHHHDHQAGRSRKIEVEQDVLLKNNLLAERNRGYFEA
RNILALNFLSSPGSGKTSLLEKIIPMFRLKHPVAVIEGDQQTTNDADRIHALGVEVIQVNTGTGCHLDALMINRAVKELN
LQNNSLLCIENVGNLVCPAMFDLGEACKVVVISVTEGDDKPLKYPNMFHEADVCVLNKTDLLDYVDFDSAQCKKNALSIN
HHLEWFEVSAKTGEGLELLMQWLENRMEQS

Sequences:

>Translated_270_residues
MCDTCGCSTDGGALLRKPGDSDYHVHIGDEGHGHEHGHDHDHDRHHHDHQAGRSRKIEVEQDVLLKNNLLAERNRGYFEA
RNILALNFLSSPGSGKTSLLEKIIPMFRLKHPVAVIEGDQQTTNDADRIHALGVEVIQVNTGTGCHLDALMINRAVKELN
LQNNSLLCIENVGNLVCPAMFDLGEACKVVVISVTEGDDKPLKYPNMFHEADVCVLNKTDLLDYVDFDSAQCKKNALSIN
HHLEWFEVSAKTGEGLELLMQWLENRMEQS
>Mature_270_residues
MCDTCGCSTDGGALLRKPGDSDYHVHIGDEGHGHEHGHDHDHDRHHHDHQAGRSRKIEVEQDVLLKNNLLAERNRGYFEA
RNILALNFLSSPGSGKTSLLEKIIPMFRLKHPVAVIEGDQQTTNDADRIHALGVEVIQVNTGTGCHLDALMINRAVKELN
LQNNSLLCIENVGNLVCPAMFDLGEACKVVVISVTEGDDKPLKYPNMFHEADVCVLNKTDLLDYVDFDSAQCKKNALSIN
HHLEWFEVSAKTGEGLELLMQWLENRMEQS

Specific function: Could be involved in nickel binding and accumulation. Binds 3.9 nickel ions per molecule [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=288, Percent_Identity=47.2222222222222, Blast_Score=242, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 30130; Mature: 30130

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDTCGCSTDGGALLRKPGDSDYHVHIGDEGHGHEHGHDHDHDRHHHDHQAGRSRKIEVE
CCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECH
QDVLLKNNLLAERNRGYFEARNILALNFLSSPGSGKTSLLEKIIPMFRLKHPVAVIEGDQ
HHHHHHHCHHHHCCCCEEHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
QTTNDADRIHALGVEVIQVNTGTGCHLDALMINRAVKELNLQNNSLLCIENVGNLVCPAM
CCCCHHHHHEEECEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
FDLGEACKVVVISVTEGDDKPLKYPNMFHEADVCVLNKTDLLDYVDFDSAQCKKNALSIN
HCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCHHHHHHHEECC
HHLEWFEVSAKTGEGLELLMQWLENRMEQS
CCEEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCDTCGCSTDGGALLRKPGDSDYHVHIGDEGHGHEHGHDHDHDRHHHDHQAGRSRKIEVE
CCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECH
QDVLLKNNLLAERNRGYFEARNILALNFLSSPGSGKTSLLEKIIPMFRLKHPVAVIEGDQ
HHHHHHHCHHHHCCCCEEHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
QTTNDADRIHALGVEVIQVNTGTGCHLDALMINRAVKELNLQNNSLLCIENVGNLVCPAM
CCCCHHHHHEEECEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
FDLGEACKVVVISVTEGDDKPLKYPNMFHEADVCVLNKTDLLDYVDFDSAQCKKNALSIN
HCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCHHHHHHHEECC
HHLEWFEVSAKTGEGLELLMQWLENRMEQS
CCEEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8326860 [H]