Click here to switch to the map view.

The map label for this gene is 119356544

Identifier: 119356544

GI number: 119356544

Start: 808188

End: 809585

Strand: Reverse

Name: 119356544

Synonym: Cpha266_0709

Alternate gene names: NA

Gene position: 809585-808188 (Counterclockwise)

Preceding gene: 119356545

Following gene: 119356543

Centisome position: 25.83

GC content: 46.57

Gene sequence:

>1398_bases
ATGAGTCTGTCTGATTTTTTTGATGAAAACCGTCATGAATCATCCGGTTTATCACAAAAAGAGCCGCCTGATCTTGACGA
TCTTGAAAGCATGTATGATGCTGAGGAGCTGATTGATCTTATCAGCCAGCTCAATGAAGACGGATTTATCCAGGAGGCCC
TTGCCGTTGCGCAAAGGCTTGAAGCCGTTTCGCCATACAATGCCGAGACCTGGTTTCATCTTGGTAACTGTCTCACCGTT
AACGGGTATTTCAACGATGCCCTTGAGGCATTCAATCAGGCAGTGCTGCTCAGTCCCGCTGACAGCGAAATGCGCCTCAA
CTACGCTCTTGCGCACTTCAATACGGGATCTCTTGACGAAGCTCTCGAAATCCTTGAGGATATGTATGTTGACTCATCGA
TTGAACGGGAGTACTCCTACTACCGGGGTATCATTCTGCAGCGGCTTGAACGGTTCACTGAATCAGAAAAAGATTTTGAA
CACTGCCTCGAACTCGATCCTGATTTTTCTGACGCATGGTATGAACTTGCCTACGGAAAAGATCTCCTGGGAAAACTCGA
AGAGAGCACGGCCTGTTACAACAAAGCACTGGACCACGATCCCTACAATATCAATGCATGGTACAACAACGGTCTGGTAC
TCAGTAAACTGAAACGATACGATGAAGCGCTTCAGTGCTACGATATGTCTCTCGCTCTTGCCGATGATTTCAGTTCCGCA
TGGTATAACCGGGCCAATGTTCTTGCCATAACGGGAAAAATCGAAGAGGCGGCAGAAAGCTATGTGAAAACTCTTGAGTT
TGAACCTGACGACCTCAATGCCCTGTACAATCTTGGTATTGCCTACGAAGAACTTGAGGAGTACAGTGAAGCTATTCTCT
GCTATCGACGCTGCATCGAGCTCAATAACGATTTCCATGATGCATGGTTTGCGCTTGCATGCTGTTATGAAGCCATCGAA
CAGTATAATGAGGGATCACTTGCCATTATTGAAGCTCTGAAGGCAATCCCTGACAGCATCGAGTTTCTGCTGCTTAAAGC
TGAAATAGAGTATAATCTCAATGAGCTCGAACACTCTCTTGAAACCTATCGACATATCATCACCCTTGACCCTGAAAGTC
CGCAGATATGGGTTGATTATGCCATGGTCCTTCGCGAAGCAGGCTATAACAACGAATCCATTGAGGCCCTTCATCAGTCG
CTGAAACTTCAGCCGCATTCGGCTGATGCCCATTTCGAGATTGCTGCCGCCTATTTTGCCATGGGGGACAAACTCAGCAC
CCTGAAAGCGCTGAGCAAGGCATTCAAAATCGACCCTGATAAAAAACAACTTTTTCAAAGCACCTTCCCGGAACTTTATC
AGCAGGATTCCGTTAGAAAAATGCTTGGCATTTCCTGA

Upstream 100 bases:

>100_bases
AAAGGGGTGGTCCGGAAATCTTGTTCTTATGAAAATTCTGTTATATTTGACTTATGCGCAGTTTGCTGTTATTACTATTT
GAAACCCATGAGGATTGTGT

Downstream 100 bases:

>100_bases
TCACCCTCGTCACCGGGACGACCTGCATGATGCAACCAGAAAAAATTCTCGGCCTTATCGGGCGAAATATAGCCTACTCA
CGCTCACCCCTGATTCATAA

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSLSDFFDENRHESSGLSQKEPPDLDDLESMYDAEELIDLISQLNEDGFIQEALAVAQRLEAVSPYNAETWFHLGNCLTV
NGYFNDALEAFNQAVLLSPADSEMRLNYALAHFNTGSLDEALEILEDMYVDSSIEREYSYYRGIILQRLERFTESEKDFE
HCLELDPDFSDAWYELAYGKDLLGKLEESTACYNKALDHDPYNINAWYNNGLVLSKLKRYDEALQCYDMSLALADDFSSA
WYNRANVLAITGKIEEAAESYVKTLEFEPDDLNALYNLGIAYEELEEYSEAILCYRRCIELNNDFHDAWFALACCYEAIE
QYNEGSLAIIEALKAIPDSIEFLLLKAEIEYNLNELEHSLETYRHIITLDPESPQIWVDYAMVLREAGYNNESIEALHQS
LKLQPHSADAHFEIAAAYFAMGDKLSTLKALSKAFKIDPDKKQLFQSTFPELYQQDSVRKMLGIS

Sequences:

>Translated_465_residues
MSLSDFFDENRHESSGLSQKEPPDLDDLESMYDAEELIDLISQLNEDGFIQEALAVAQRLEAVSPYNAETWFHLGNCLTV
NGYFNDALEAFNQAVLLSPADSEMRLNYALAHFNTGSLDEALEILEDMYVDSSIEREYSYYRGIILQRLERFTESEKDFE
HCLELDPDFSDAWYELAYGKDLLGKLEESTACYNKALDHDPYNINAWYNNGLVLSKLKRYDEALQCYDMSLALADDFSSA
WYNRANVLAITGKIEEAAESYVKTLEFEPDDLNALYNLGIAYEELEEYSEAILCYRRCIELNNDFHDAWFALACCYEAIE
QYNEGSLAIIEALKAIPDSIEFLLLKAEIEYNLNELEHSLETYRHIITLDPESPQIWVDYAMVLREAGYNNESIEALHQS
LKLQPHSADAHFEIAAAYFAMGDKLSTLKALSKAFKIDPDKKQLFQSTFPELYQQDSVRKMLGIS
>Mature_464_residues
SLSDFFDENRHESSGLSQKEPPDLDDLESMYDAEELIDLISQLNEDGFIQEALAVAQRLEAVSPYNAETWFHLGNCLTVN
GYFNDALEAFNQAVLLSPADSEMRLNYALAHFNTGSLDEALEILEDMYVDSSIEREYSYYRGIILQRLERFTESEKDFEH
CLELDPDFSDAWYELAYGKDLLGKLEESTACYNKALDHDPYNINAWYNNGLVLSKLKRYDEALQCYDMSLALADDFSSAW
YNRANVLAITGKIEEAAESYVKTLEFEPDDLNALYNLGIAYEELEEYSEAILCYRRCIELNNDFHDAWFALACCYEAIEQ
YNEGSLAIIEALKAIPDSIEFLLLKAEIEYNLNELEHSLETYRHIITLDPESPQIWVDYAMVLREAGYNNESIEALHQSL
KLQPHSADAHFEIAAAYFAMGDKLSTLKALSKAFKIDPDKKQLFQSTFPELYQQDSVRKMLGIS

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=381, Percent_Identity=25.9842519685039, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI32307150, Length=381, Percent_Identity=25.9842519685039, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI224809432, Length=365, Percent_Identity=26.3013698630137, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI167466175, Length=200, Percent_Identity=23.5, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI167466177, Length=200, Percent_Identity=23.5, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI118766330, Length=241, Percent_Identity=23.2365145228216, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI118766328, Length=241, Percent_Identity=23.2365145228216, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=394, Percent_Identity=25.6345177664975, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115532690, Length=394, Percent_Identity=25.6345177664975, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25147174, Length=241, Percent_Identity=21.9917012448133, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647755, Length=398, Percent_Identity=24.3718592964824, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585827, Length=398, Percent_Identity=24.3718592964824, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585829, Length=398, Percent_Identity=24.3718592964824, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647123, Length=267, Percent_Identity=22.4719101123595, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 53316; Mature: 53184

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSDFFDENRHESSGLSQKEPPDLDDLESMYDAEELIDLISQLNEDGFIQEALAVAQRL
CCCHHHHHCCCCHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAVSPYNAETWFHLGNCLTVNGYFNDALEAFNQAVLLSPADSEMRLNYALAHFNTGSLDE
HHCCCCCCCHHEECCCEEEECCCHHHHHHHHCCEEEECCCCCCCEEEEEEEECCCCCHHH
ALEILEDMYVDSSIEREYSYYRGIILQRLERFTESEKDFEHCLELDPDFSDAWYELAYGK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCH
DLLGKLEESTACYNKALDHDPYNINAWYNNGLVLSKLKRYDEALQCYDMSLALADDFSSA
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYNRANVLAITGKIEEAAESYVKTLEFEPDDLNALYNLGIAYEELEEYSEAILCYRRCIE
HHCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LNNDFHDAWFALACCYEAIEQYNEGSLAIIEALKAIPDSIEFLLLKAEIEYNLNELEHSL
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHEEEEHHHHCCHHHHHHHH
ETYRHIITLDPESPQIWVDYAMVLREAGYNNESIEALHQSLKLQPHSADAHFEIAAAYFA
HHHHEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
MGDKLSTLKALSKAFKIDPDKKQLFQSTFPELYQQDSVRKMLGIS
HCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLSDFFDENRHESSGLSQKEPPDLDDLESMYDAEELIDLISQLNEDGFIQEALAVAQRL
CCHHHHHCCCCHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAVSPYNAETWFHLGNCLTVNGYFNDALEAFNQAVLLSPADSEMRLNYALAHFNTGSLDE
HHCCCCCCCHHEECCCEEEECCCHHHHHHHHCCEEEECCCCCCCEEEEEEEECCCCCHHH
ALEILEDMYVDSSIEREYSYYRGIILQRLERFTESEKDFEHCLELDPDFSDAWYELAYGK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCH
DLLGKLEESTACYNKALDHDPYNINAWYNNGLVLSKLKRYDEALQCYDMSLALADDFSSA
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYNRANVLAITGKIEEAAESYVKTLEFEPDDLNALYNLGIAYEELEEYSEAILCYRRCIE
HHCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LNNDFHDAWFALACCYEAIEQYNEGSLAIIEALKAIPDSIEFLLLKAEIEYNLNELEHSL
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHEEEEHHHHCCHHHHHHHH
ETYRHIITLDPESPQIWVDYAMVLREAGYNNESIEALHQSLKLQPHSADAHFEIAAAYFA
HHHHEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
MGDKLSTLKALSKAFKIDPDKKQLFQSTFPELYQQDSVRKMLGIS
HCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]