| Definition | Chlorobium phaeobacteroides DSM 266 chromosome, complete genome. |
|---|---|
| Accession | NC_008639 |
| Length | 3,133,902 |
Click here to switch to the map view.
The map label for this gene is rotA [H]
Identifier: 119356539
GI number: 119356539
Start: 804567
End: 805061
Strand: Reverse
Name: rotA [H]
Synonym: Cpha266_0704
Alternate gene names: 119356539
Gene position: 805061-804567 (Counterclockwise)
Preceding gene: 119356540
Following gene: 119356538
Centisome position: 25.69
GC content: 48.89
Gene sequence:
>495_bases ATGCCCGACACATTTACCATTCAGACAAGCCTTGGAGATATAACGATCAGGCTTTACGACGATACTCCGCTTCACCGGGA CAACTTCAAAAAACTCGTTTCGGAAAACTATTACGACGGCATTCGTTTTCACCGTGTGATCGAAGGTTTCATGATCCAGA CAGGCGATCCGCTCTCCCGCCATGAGAACAAGCGTATGCTGCACGGCACCGGAGGCCCTTCAACTCGTATCGATGCGGAA ATAAAACACTCCAACAAAAAAGGCACGCTTGCAGCAGCAAGGGATAACAACCCTGCCAAAGCATCGTCAGGCAGTCAGTT TTATATCAATCATGCCGACAACAATTTTCTCGACGGCCAGTATACGGTTTTCGGCGTCGTCGAAGAGGGAATGGGCGTTG TGGAAAAAATAGCCTCCGTAAAAACAGACCCCAACGACAATCCTGTCGATCCCGTAACGATCACCACCATCGTGCCTGTT TTACAAGCATCATAG
Upstream 100 bases:
>100_bases GCCGACTATCCCGGCTCAACCGGAGCGATACTTTCACAAAGAGCACTGTGGCAGATTTCAGGACAACAGTAATCACGTTC AACATTTTTCAAACATTCCC
Downstream 100 bases:
>100_bases ACACGGCAATGGAGAGCATAGCGTCCAACCTTAACCGTATCAGGGAACAGATCGGCACTCTCTCGGTGAAAGCCGGCAGA GAACCCTCTGATGTTCGACT
Product: peptidyl-prolyl cis-trans isomerase, cyclophilin type
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 164; Mature: 163
Protein sequence:
>164_residues MPDTFTIQTSLGDITIRLYDDTPLHRDNFKKLVSENYYDGIRFHRVIEGFMIQTGDPLSRHENKRMLHGTGGPSTRIDAE IKHSNKKGTLAAARDNNPAKASSGSQFYINHADNNFLDGQYTVFGVVEEGMGVVEKIASVKTDPNDNPVDPVTITTIVPV LQAS
Sequences:
>Translated_164_residues MPDTFTIQTSLGDITIRLYDDTPLHRDNFKKLVSENYYDGIRFHRVIEGFMIQTGDPLSRHENKRMLHGTGGPSTRIDAE IKHSNKKGTLAAARDNNPAKASSGSQFYINHADNNFLDGQYTVFGVVEEGMGVVEKIASVKTDPNDNPVDPVTITTIVPV LQAS >Mature_163_residues PDTFTIQTSLGDITIRLYDDTPLHRDNFKKLVSENYYDGIRFHRVIEGFMIQTGDPLSRHENKRMLHGTGGPSTRIDAEI KHSNKKGTLAAARDNNPAKASSGSQFYINHADNNFLDGQYTVFGVVEEGMGVVEKIASVKTDPNDNPVDPVTITTIVPVL QAS
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. This protein is not essential for growth. Presumably plays a role in signal transduction [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=163, Percent_Identity=35.5828220858896, Blast_Score=97, Evalue=4e-21, Organism=Homo sapiens, GI24308049, Length=157, Percent_Identity=37.5796178343949, Blast_Score=92, Evalue=2e-19, Organism=Homo sapiens, GI19557636, Length=136, Percent_Identity=36.0294117647059, Blast_Score=80, Evalue=8e-16, Organism=Homo sapiens, GI20911035, Length=160, Percent_Identity=36.25, Blast_Score=78, Evalue=3e-15, Organism=Homo sapiens, GI5454154, Length=160, Percent_Identity=33.125, Blast_Score=77, Evalue=6e-15, Organism=Homo sapiens, GI4758950, Length=155, Percent_Identity=38.7096774193548, Blast_Score=76, Evalue=1e-14, Organism=Homo sapiens, GI10863927, Length=137, Percent_Identity=37.956204379562, Blast_Score=73, Evalue=1e-13, Organism=Homo sapiens, GI5031987, Length=139, Percent_Identity=38.8489208633094, Blast_Score=69, Evalue=1e-12, Organism=Homo sapiens, GI22547212, Length=150, Percent_Identity=32.6666666666667, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI7657473, Length=150, Percent_Identity=32.6666666666667, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI22547215, Length=150, Percent_Identity=32.6666666666667, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI64276486, Length=160, Percent_Identity=31.875, Blast_Score=65, Evalue=2e-11, Organism=Escherichia coli, GI1789763, Length=160, Percent_Identity=39.375, Blast_Score=85, Evalue=3e-18, Organism=Escherichia coli, GI1786736, Length=167, Percent_Identity=35.3293413173653, Blast_Score=77, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17539496, Length=154, Percent_Identity=37.012987012987, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17506311, Length=161, Percent_Identity=38.5093167701863, Blast_Score=93, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71980590, Length=146, Percent_Identity=39.7260273972603, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71980594, Length=148, Percent_Identity=39.1891891891892, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17532643, Length=153, Percent_Identity=33.9869281045752, Blast_Score=76, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17552780, Length=155, Percent_Identity=36.7741935483871, Blast_Score=74, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17565860, Length=161, Percent_Identity=34.1614906832298, Blast_Score=72, Evalue=9e-14, Organism=Caenorhabditis elegans, GI71997782, Length=161, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17506307, Length=156, Percent_Identity=36.5384615384615, Blast_Score=70, Evalue=3e-13, Organism=Caenorhabditis elegans, GI32563659, Length=165, Percent_Identity=32.7272727272727, Blast_Score=69, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17539498, Length=154, Percent_Identity=35.7142857142857, Blast_Score=67, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17551282, Length=122, Percent_Identity=40.9836065573771, Blast_Score=67, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17551284, Length=122, Percent_Identity=40.9836065573771, Blast_Score=67, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6321848, Length=159, Percent_Identity=37.1069182389937, Blast_Score=72, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6320510, Length=157, Percent_Identity=38.2165605095541, Blast_Score=71, Evalue=7e-14, Organism=Saccharomyces cerevisiae, GI6323562, Length=143, Percent_Identity=35.6643356643357, Blast_Score=69, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6320359, Length=137, Percent_Identity=32.1167883211679, Blast_Score=64, Evalue=1e-11, Organism=Drosophila melanogaster, GI17986117, Length=154, Percent_Identity=38.961038961039, Blast_Score=105, Evalue=1e-23, Organism=Drosophila melanogaster, GI24586038, Length=164, Percent_Identity=35.9756097560976, Blast_Score=87, Evalue=7e-18, Organism=Drosophila melanogaster, GI19922376, Length=158, Percent_Identity=31.6455696202532, Blast_Score=83, Evalue=9e-17, Organism=Drosophila melanogaster, GI24652460, Length=156, Percent_Identity=31.4102564102564, Blast_Score=79, Evalue=1e-15, Organism=Drosophila melanogaster, GI20130249, Length=164, Percent_Identity=37.8048780487805, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI17136360, Length=151, Percent_Identity=34.4370860927152, Blast_Score=76, Evalue=8e-15, Organism=Drosophila melanogaster, GI19922912, Length=153, Percent_Identity=35.9477124183007, Blast_Score=74, Evalue=4e-14, Organism=Drosophila melanogaster, GI24664125, Length=134, Percent_Identity=36.5671641791045, Blast_Score=67, Evalue=6e-12, Organism=Drosophila melanogaster, GI21357783, Length=134, Percent_Identity=36.5671641791045, Blast_Score=67, Evalue=6e-12, Organism=Drosophila melanogaster, GI21355677, Length=163, Percent_Identity=33.7423312883436, Blast_Score=65, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 18133; Mature: 18002
Theoretical pI: Translated: 6.24; Mature: 6.24
Prosite motif: PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPDTFTIQTSLGDITIRLYDDTPLHRDNFKKLVSENYYDGIRFHRVIEGFMIQTGDPLSR CCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCC HENKRMLHGTGGPSTRIDAEIKHSNKKGTLAAARDNNPAKASSGSQFYINHADNNFLDGQ CCCCEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEECCC YTVFGVVEEGMGVVEKIASVKTDPNDNPVDPVTITTIVPVLQAS EEEEEEEHHCHHHHHHHHHCCCCCCCCCCCCEEHEEEEEHHCCC >Mature Secondary Structure PDTFTIQTSLGDITIRLYDDTPLHRDNFKKLVSENYYDGIRFHRVIEGFMIQTGDPLSR CCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCC HENKRMLHGTGGPSTRIDAEIKHSNKKGTLAAARDNNPAKASSGSQFYINHADNNFLDGQ CCCCEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEECCC YTVFGVVEEGMGVVEKIASVKTDPNDNPVDPVTITTIVPVLQAS EEEEEEEHHCHHHHHHHHHCCCCCCCCCCCCEEHEEEEEHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7948017 [H]