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The map label for this gene is tadA [H]

Identifier: 119356459

GI number: 119356459

Start: 701399

End: 701860

Strand: Direct

Name: tadA [H]

Synonym: Cpha266_0624

Alternate gene names: 119356459

Gene position: 701399-701860 (Clockwise)

Preceding gene: 119356457

Following gene: 119356462

Centisome position: 22.38

GC content: 48.05

Gene sequence:

>462_bases
ATGAATTTTACTCACTATATGGCAATAGCGTTCAAAGAAGCGCTCAAGGCTGTTGAAAAAAAAGAGGTTCCTGTCGGGGC
GGTTGTTTTTGACAGCAACGGAAATATTGTTGGTAAAGGGTACAATCAGGTTGAGGAGCTTTCAGATGCAACGGCTCATG
CGGAGATGATCGCTCTGACTTCGGCAATGGCCACACTCAATACAAAGTATCTCGACGATTGTACTATTGCTGTTACGATG
GAGCCATGTCCCATGTGTGCCGGAGCTCTGGTTAACGCGAAGATCGGACGGCTGATTTTTGGAGCATATGATCCCAAAAT
GGGGGCGGCAGGTACGGTGCTCAATATTACCGGATGCAGAGAGCTGAACCATAATCCTGAAGTTTTTGGCGGAATCATGG
AGCAGCAGTGCAGCGGCCTTTTACAGGATTTTTTCAGAGAGCTGAGAGGCCGGTCGCGTTAA

Upstream 100 bases:

>100_bases
TGCCGGAAACAAAGGGAGTAAAATCAACCCTCATTATAGTAAATTTAAATGTGTTACTGAAATCATGAACTCGGTAACCA
TAAAAAAATTAAAAATAAAT

Downstream 100 bases:

>100_bases
GGTATTCAGATGCATCGGAGGAACTGTTCGTTTGCTTTTGCCATGTATTCTGCGCATCAATCCCCTTTTTTTTCAGTGGT
GATATTTTCTCTGATGATCT

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MNFTHYMAIAFKEALKAVEKKEVPVGAVVFDSNGNIVGKGYNQVEELSDATAHAEMIALTSAMATLNTKYLDDCTIAVTM
EPCPMCAGALVNAKIGRLIFGAYDPKMGAAGTVLNITGCRELNHNPEVFGGIMEQQCSGLLQDFFRELRGRSR

Sequences:

>Translated_153_residues
MNFTHYMAIAFKEALKAVEKKEVPVGAVVFDSNGNIVGKGYNQVEELSDATAHAEMIALTSAMATLNTKYLDDCTIAVTM
EPCPMCAGALVNAKIGRLIFGAYDPKMGAAGTVLNITGCRELNHNPEVFGGIMEQQCSGLLQDFFRELRGRSR
>Mature_153_residues
MNFTHYMAIAFKEALKAVEKKEVPVGAVVFDSNGNIVGKGYNQVEELSDATAHAEMIALTSAMATLNTKYLDDCTIAVTM
EPCPMCAGALVNAKIGRLIFGAYDPKMGAAGTVLNITGCRELNHNPEVFGGIMEQQCSGLLQDFFRELRGRSR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=117, Percent_Identity=36.7521367521368, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=41.7218543046358, Blast_Score=129, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=33.7837837837838, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17555996, Length=98, Percent_Identity=41.8367346938776, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=34.6938775510204, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=157, Percent_Identity=29.9363057324841, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=31.9727891156463, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16553; Mature: 16553

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFTHYMAIAFKEALKAVEKKEVPVGAVVFDSNGNIVGKGYNQVEELSDATAHAEMIALT
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH
SAMATLNTKYLDDCTIAVTMEPCPMCAGALVNAKIGRLIFGAYDPKMGAAGTVLNITGCR
HHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCEEEECCCC
ELNHNPEVFGGIMEQQCSGLLQDFFRELRGRSR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNFTHYMAIAFKEALKAVEKKEVPVGAVVFDSNGNIVGKGYNQVEELSDATAHAEMIALT
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH
SAMATLNTKYLDDCTIAVTMEPCPMCAGALVNAKIGRLIFGAYDPKMGAAGTVLNITGCR
HHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCEEEECCCC
ELNHNPEVFGGIMEQQCSGLLQDFFRELRGRSR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]