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The map label for this gene is gpmA

Identifier: 119356462

GI number: 119356462

Start: 704589

End: 705332

Strand: Direct

Name: gpmA

Synonym: Cpha266_0627

Alternate gene names: 119356462

Gene position: 704589-705332 (Clockwise)

Preceding gene: 119356459

Following gene: 119356463

Centisome position: 22.48

GC content: 48.79

Gene sequence:

>744_bases
ATGATCAAGCTGGTCTTGTTGCGACATGGGGAAAGTCAGTGGAACAGGGAAAACCGATTTACAGGATGGCATGATATTGA
TTTGACTGAAAATGGCCGAAACGAGGCTTTTCAGGCTGGTCGACTCATGAAAGAAGCCGGACTGGTTTTCGATATGGCAT
ATACCTCCGTTTTGAAAAGAGCAATCAGGACGCTCTGGAACGCCATGGATTCCATGGACCTCATGTGGATTTCTGTGTTC
AAGAGCTGGCGTCTCAACGAACGCCATTATGGTGCTCTTCAGGGGCTCAACAAGTCGGAAACTTCCCGGAAATACGGCGA
GGAGCAGGTGCTTGTATGGCGAAGAAGCTATGATACGCCTCCGCCGCTGCTCGAAAAGAGTGACGCTCGTTATCCCGGAA
CCGATCCGCGTTATGGAGACCTCTCTGAAGCGGAAATCCCTCTAAGCGAATGTCTCAAGGATACCGTTGAGCGTTTTCTT
CCGATCTGGCATGAAACCATAGCTCCGCAACTGCGCAAGGGCAAGCGTGTCATTATTGTCGCACACGGCAACTCATTACG
TGCTTTAGTGAAATATCTTGATAATATTTCCGAAGAAGATATTGTCGGCTTGAATATCCCGACAGGCATTCCGCTTGTAT
ACGAGCTCGATGATGATCTCAAGCCCTTGAAAAACTATTACCTTGGGGATCAGGAAGCCTTGAAAAAAGCTGTCGATGCC
GTTGCCGGACAGTCAAAAGCGTAG

Upstream 100 bases:

>100_bases
GAACGTTTGAGAAAAGTTCTTCAGAATATTAAATTACGAGCCAAATAAAAAAGGGAGAGATCCTTCCTGTTATGAAAAAT
ATCCGGAAAAAGGGGGAGTT

Downstream 100 bases:

>100_bases
TCCCGGATATTTTTGCAACGTATGGATATAATGTAAAAACCTTATATTCTGCACTCTTGATGACGGGACGACCTTTTTTT
TGAAACTTTTAGAAAAGATG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKRAIRTLWNAMDSMDLMWISVF
KSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTPPPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFL
PIWHETIAPQLRKGKRVIIVAHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDA
VAGQSKA

Sequences:

>Translated_247_residues
MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKRAIRTLWNAMDSMDLMWISVF
KSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTPPPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFL
PIWHETIAPQLRKGKRVIIVAHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDA
VAGQSKA
>Mature_247_residues
MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKRAIRTLWNAMDSMDLMWISVF
KSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTPPPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFL
PIWHETIAPQLRKGKRVIIVAHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDA
VAGQSKA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=248, Percent_Identity=54.8387096774194, Blast_Score=294, Evalue=5e-80,
Organism=Homo sapiens, GI4505753, Length=248, Percent_Identity=57.6612903225806, Blast_Score=294, Evalue=6e-80,
Organism=Homo sapiens, GI71274132, Length=248, Percent_Identity=55.241935483871, Blast_Score=279, Evalue=2e-75,
Organism=Homo sapiens, GI4502445, Length=250, Percent_Identity=47.2, Blast_Score=241, Evalue=4e-64,
Organism=Homo sapiens, GI40353764, Length=250, Percent_Identity=47.2, Blast_Score=241, Evalue=4e-64,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=56.5217391304348, Blast_Score=184, Evalue=4e-47,
Organism=Escherichia coli, GI1786970, Length=247, Percent_Identity=64.3724696356275, Blast_Score=337, Evalue=5e-94,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=51.219512195122, Blast_Score=240, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6324516, Length=281, Percent_Identity=32.3843416370107, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=32.1070234113712, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24646216, Length=249, Percent_Identity=55.421686746988, Blast_Score=282, Evalue=1e-76,
Organism=Drosophila melanogaster, GI85725270, Length=249, Percent_Identity=54.2168674698795, Blast_Score=270, Evalue=6e-73,
Organism=Drosophila melanogaster, GI85725272, Length=249, Percent_Identity=54.2168674698795, Blast_Score=270, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24650981, Length=249, Percent_Identity=54.2168674698795, Blast_Score=270, Evalue=6e-73,
Organism=Drosophila melanogaster, GI28571815, Length=246, Percent_Identity=40.650406504065, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28571817, Length=246, Percent_Identity=40.650406504065, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24648979, Length=246, Percent_Identity=40.650406504065, Blast_Score=182, Evalue=1e-46,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_CHLPD (A1BE55)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911106.1
- ProteinModelPortal:   A1BE55
- SMR:   A1BE55
- STRING:   A1BE55
- GeneID:   4569780
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0627
- NMPDR:   fig|290317.7.peg.660
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 28363; Mature: 28363

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKR
CEEEEEEECCCHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
AIRTLWNAMDSMDLMWISVFKSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTP
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCHHEEEEECCCCCC
PPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFLPIWHETIAPQLRKGKRVIIV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDA
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHH
VAGQSKA
HCCCCCC
>Mature Secondary Structure
MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKR
CEEEEEEECCCHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
AIRTLWNAMDSMDLMWISVFKSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTP
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCHHEEEEECCCCCC
PPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFLPIWHETIAPQLRKGKRVIIV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDA
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHH
VAGQSKA
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA