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The map label for this gene is sucC

Identifier: 119356458

GI number: 119356458

Start: 700083

End: 701261

Strand: Reverse

Name: sucC

Synonym: Cpha266_0623

Alternate gene names: 119356458

Gene position: 701261-700083 (Counterclockwise)

Preceding gene: 119356460

Following gene: 119356454

Centisome position: 22.38

GC content: 47.67

Gene sequence:

>1179_bases
ATGAACATTCATGAATATCAAGGCAAAGATATCCTGAGAAAATTCGGTGTGGCGGTTCCAAAAGGCATCGTGGCGTTTTC
ACCTGAAGAAGCTAAACAGGCCGCTATTCAGCTTTTTGAAGAGCAGAACAGCCCTGTCGTAGTAATTAAAGCTCAAATCC
ATGCGGGAGGCCGCGGAAAAGCCGGCGGAGTCAAACTCGCTAAATCCCCTGAGGAGGTCTTTGATATTGCCCAGCAAATG
CTTGGCATTACCCTTGTGACCCACCAGACCGGACCTGAAGGTAAAGAGGTTCGACGATTACTCGTTGAAGAGGGGATGAA
CATCGATAAAGAGTTTTATGTGGGCATTACCCTTGACCGCTCAACATCGCAAAACGTGTTGATGGTTTCAACCGAAGGCG
GCATGGAAATCGAGAAAGTCGCTGAAGAAACACCGGAAAAACTCCTGAAAATCCAGGTGAATCCTCTTTTTGGATTACAG
GCTTTCCAGGCCCGTCAGGCAGCGTTTTTCCTTGAACTTGAGGGAGAGCAATTCAAAAACACCGTCAAGTTCATCACTGC
CCTCTACAACGCTTACACCTCTATTGATGCGGCTATTGCTGAAATCAATCCTCTTGTTGTCACCAAAGAGGGACGCGTTC
TGGCTCTTGATGCCAAAATAAACTTCGACTCTAACGCATTGTTCCGTCACAAGGATTTTCTTGAACTGCGCGATATCAGC
GAAGAGGATCCGTTTGAAGTAGAAGCATCTAAATCCAATCTCAATTATGTTCGTCTTGACGGAAACGTCGGCTGTATGGT
CAACGGCGCCGGACTTGCAATGGGAACCATGGATATGATACAACTTGCCGGCGGACGACCCGCAAATTTCCTCGATGTGG
GAGGTGGAGCAAGCCCGCAAACTGTTGAAGAGGGATTCAAAATCATTCTGAGCGATAAAAATGTCAAGGCTATTCTTGTC
AACATTTTTGGTGGTATTGTCCGCTGCGATCGCGTTGCCGGAGGCATTATCGAGGCGGCAAAAAAAGTTGACCTCCATCT
GCCGGTAATCGTAAGGCTTGAAGGAACCAATGCCTCAATTGCACAGAAGATGCTTGACGAATCGGGATTGAACCTCATTG
CTGCCAAAGGGCTTCACGATGCGGCAAAAAAAGTGCATGAAGCGCTTGAGCCGGCATAA

Upstream 100 bases:

>100_bases
ATTTCAGTAACACATTTAAATTTACTATAATGAGGGTTGATTTTACTCCCTTTGTTTCCGGCAGAAACTGCAGGAAGATA
ACCATCCATAACTCACCAAT

Downstream 100 bases:

>100_bases
TCCTTTCGAATAAAAACAAACAAGCCTGCTGCCCGAAAACAGCGGGCTTGTTTGTTTTCAGGCTGCTCCCTGTCAAGACC
AACGAGCTTTCCGATCACCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNIHEYQGKDILRKFGVAVPKGIVAFSPEEAKQAAIQLFEEQNSPVVVIKAQIHAGGRGKAGGVKLAKSPEEVFDIAQQM
LGITLVTHQTGPEGKEVRRLLVEEGMNIDKEFYVGITLDRSTSQNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPLFGLQ
AFQARQAAFFLELEGEQFKNTVKFITALYNAYTSIDAAIAEINPLVVTKEGRVLALDAKINFDSNALFRHKDFLELRDIS
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDMIQLAGGRPANFLDVGGGASPQTVEEGFKIILSDKNVKAILV
NIFGGIVRCDRVAGGIIEAAKKVDLHLPVIVRLEGTNASIAQKMLDESGLNLIAAKGLHDAAKKVHEALEPA

Sequences:

>Translated_392_residues
MNIHEYQGKDILRKFGVAVPKGIVAFSPEEAKQAAIQLFEEQNSPVVVIKAQIHAGGRGKAGGVKLAKSPEEVFDIAQQM
LGITLVTHQTGPEGKEVRRLLVEEGMNIDKEFYVGITLDRSTSQNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPLFGLQ
AFQARQAAFFLELEGEQFKNTVKFITALYNAYTSIDAAIAEINPLVVTKEGRVLALDAKINFDSNALFRHKDFLELRDIS
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDMIQLAGGRPANFLDVGGGASPQTVEEGFKIILSDKNVKAILV
NIFGGIVRCDRVAGGIIEAAKKVDLHLPVIVRLEGTNASIAQKMLDESGLNLIAAKGLHDAAKKVHEALEPA
>Mature_392_residues
MNIHEYQGKDILRKFGVAVPKGIVAFSPEEAKQAAIQLFEEQNSPVVVIKAQIHAGGRGKAGGVKLAKSPEEVFDIAQQM
LGITLVTHQTGPEGKEVRRLLVEEGMNIDKEFYVGITLDRSTSQNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPLFGLQ
AFQARQAAFFLELEGEQFKNTVKFITALYNAYTSIDAAIAEINPLVVTKEGRVLALDAKINFDSNALFRHKDFLELRDIS
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDMIQLAGGRPANFLDVGGGASPQTVEEGFKIILSDKNVKAILV
NIFGGIVRCDRVAGGIIEAAKKVDLHLPVIVRLEGTNASIAQKMLDESGLNLIAAKGLHDAAKKVHEALEPA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=46.6836734693878, Blast_Score=342, Evalue=4e-94,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=46.2532299741602, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=46.2809917355372, Blast_Score=309, Evalue=4e-84,
Organism=Escherichia coli, GI1786948, Length=390, Percent_Identity=53.3333333333333, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=41.7085427135678, Blast_Score=324, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=41.9437340153453, Blast_Score=304, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=43.5768261964735, Blast_Score=336, Evalue=3e-93,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=46.7336683417085, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=42.6735218508997, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=42.6735218508997, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI281361397, Length=390, Percent_Identity=42.8205128205128, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI281361395, Length=390, Percent_Identity=42.8205128205128, Blast_Score=304, Evalue=8e-83,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_CHLPD (A1BE51)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911102.1
- ProteinModelPortal:   A1BE51
- SMR:   A1BE51
- STRING:   A1BE51
- GeneID:   4569334
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0623
- NMPDR:   fig|290317.7.peg.656
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   EGDIGCM
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42465; Mature: 42465

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKDILRKFGVAVPKGIVAFSPEEAKQAAIQLFEEQNSPVVVIKAQIHAGGRGK
CCCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
AGGVKLAKSPEEVFDIAQQMLGITLVTHQTGPEGKEVRRLLVEEGMNIDKEFYVGITLDR
CCCEEECCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEC
STSQNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPLFGLQAFQARQAAFFLELEGEQFKN
CCCCCEEEEECCCCCHHHHHHHHCHHHEEEEEECCCCCHHHHHHCCEEEEEEECCHHHHH
TVKFITALYNAYTSIDAAIAEINPLVVTKEGRVLALDAKINFDSNALFRHKDFLELRDIS
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCC
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDMIQLAGGRPANFLDVGGGASPQ
CCCCCEEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCCH
TVEEGFKIILSDKNVKAILVNIFGGIVRCDRVAGGIIEAAKKVDLHLPVIVRLEGTNASI
HHHCCCEEEEECCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCEEECEEEEEECCCCHHH
AQKMLDESGLNLIAAKGLHDAAKKVHEALEPA
HHHHHHHCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQGKDILRKFGVAVPKGIVAFSPEEAKQAAIQLFEEQNSPVVVIKAQIHAGGRGK
CCCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
AGGVKLAKSPEEVFDIAQQMLGITLVTHQTGPEGKEVRRLLVEEGMNIDKEFYVGITLDR
CCCEEECCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEC
STSQNVLMVSTEGGMEIEKVAEETPEKLLKIQVNPLFGLQAFQARQAAFFLELEGEQFKN
CCCCCEEEEECCCCCHHHHHHHHCHHHEEEEEECCCCCHHHHHHCCEEEEEEECCHHHHH
TVKFITALYNAYTSIDAAIAEINPLVVTKEGRVLALDAKINFDSNALFRHKDFLELRDIS
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCC
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDMIQLAGGRPANFLDVGGGASPQ
CCCCCEEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCCH
TVEEGFKIILSDKNVKAILVNIFGGIVRCDRVAGGIIEAAKKVDLHLPVIVRLEGTNASI
HHHCCCEEEEECCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCEEECEEEEEECCCCHHH
AQKMLDESGLNLIAAKGLHDAAKKVHEALEPA
HHHHHHHCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA