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The map label for this gene is trpD

Identifier: 119356420

GI number: 119356420

Start: 654284

End: 655339

Strand: Reverse

Name: trpD

Synonym: Cpha266_0584

Alternate gene names: 119356420

Gene position: 655339-654284 (Counterclockwise)

Preceding gene: 119356423

Following gene: 119356419

Centisome position: 20.91

GC content: 51.7

Gene sequence:

>1056_bases
ATGCCTCAAAAGAAGTTACTCAACATGCTGATGGCAGGCAAAGACTTGGCCCGGGAAGAAATGACGCTCTGCATGAACAA
TATCATGGATGGCGCATTTTCTGATATTGTCCTGGCAGCCCTGCTTGCCCTGCTGCAAAAAAAAGGCGTTACCGCTGATG
AAGCAGCCGGAGCCTATGCAAGTATCATGGCACGAGCAACCCTCTGCAAACTTGATGAGGATGCCGTTGACACTTGCGGC
ACGGGAGGCGATAATACCGGCACATTCAACATCTCCACCGCTGCGGCCATTATTGCCTGCGGAGCCGGTGTCAGCATAGC
AAAACATGGCAACCGTTCGATGACCAGCCAATGCGGCAGCGCCGATGTGCTTGAAGCTCTTGGTTTCGCCATTGATCTGC
CTCCGTCTGCAACCGAAGAACTCTTCAGACAAACCGGCTTTGCCTTTCTTTTCGCACCGATGTACCACCCTTCGATGAAA
GCTGTTGCCCATGTACGAAGGGAGCTGGGCATCAGGACAATCTTTAATATGCTCGGACCTCTGCTCAACCCGGCTGGAGT
AAAAAGGCAGCTTGTCGGCGTCTTTGAACCAGAGCTGATGGATCTCTACGGTACGGTTCTGCTGGCAACCGGATGTCGTC
ACTCTCTGATTGTTCATGGTGAAACTGAAACCGGAGCAGCTTTCGATGAACCAAGCATCTCCGGCCCAACCCATATTCTG
GAGCTGCACGAAGGCGTCATGGCGCGACATATCGTCCACCCAGAAGATTTCGGTTTCATCCGCTGCCCGATCGAGGATCT
CGCTGGTGGCAATCGTGAAGAAAACGCCATCATTATCCGAAATATTCTCGACGGAAGCGCAACCCGGGCAAAAACCGAAG
CTGCGCTCTACGCTGCTGCTATGACCTGTTATGTTTCAGGTAAAGCAAGCTGTATTGATGAGGGGGTATGCATGGCAAGT
GATTCACTTGAAAGTGGACAAGCTTCATGCAAATTCACAGCAATCCTGCAGCTCAACAGAGAACTCTCCGGCAAGCATAA
AGCACTGATCAACTAA

Upstream 100 bases:

>100_bases
TCAGGGCATCGTAACGAGCCGCTTGAAAAACATCTGATTCTTGTTATTATTTACATTTACATTTACGAATATTCCTTTCA
TTTGCCAACCATATAGTTCC

Downstream 100 bases:

>100_bases
ACGCTTATATTTTTGCCGAAAAACTTGTATTATAGTTGCTTCATTTTCCAGTTGAAGCCGAGAAACATTGTATCATGAAC
GGTCGCAACACCATCTATCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPQKKLLNMLMAGKDLAREEMTLCMNNIMDGAFSDIVLAALLALLQKKGVTADEAAGAYASIMARATLCKLDEDAVDTCG
TGGDNTGTFNISTAAAIIACGAGVSIAKHGNRSMTSQCGSADVLEALGFAIDLPPSATEELFRQTGFAFLFAPMYHPSMK
AVAHVRRELGIRTIFNMLGPLLNPAGVKRQLVGVFEPELMDLYGTVLLATGCRHSLIVHGETETGAAFDEPSISGPTHIL
ELHEGVMARHIVHPEDFGFIRCPIEDLAGGNREENAIIIRNILDGSATRAKTEAALYAAAMTCYVSGKASCIDEGVCMAS
DSLESGQASCKFTAILQLNRELSGKHKALIN

Sequences:

>Translated_351_residues
MPQKKLLNMLMAGKDLAREEMTLCMNNIMDGAFSDIVLAALLALLQKKGVTADEAAGAYASIMARATLCKLDEDAVDTCG
TGGDNTGTFNISTAAAIIACGAGVSIAKHGNRSMTSQCGSADVLEALGFAIDLPPSATEELFRQTGFAFLFAPMYHPSMK
AVAHVRRELGIRTIFNMLGPLLNPAGVKRQLVGVFEPELMDLYGTVLLATGCRHSLIVHGETETGAAFDEPSISGPTHIL
ELHEGVMARHIVHPEDFGFIRCPIEDLAGGNREENAIIIRNILDGSATRAKTEAALYAAAMTCYVSGKASCIDEGVCMAS
DSLESGQASCKFTAILQLNRELSGKHKALIN
>Mature_350_residues
PQKKLLNMLMAGKDLAREEMTLCMNNIMDGAFSDIVLAALLALLQKKGVTADEAAGAYASIMARATLCKLDEDAVDTCGT
GGDNTGTFNISTAAAIIACGAGVSIAKHGNRSMTSQCGSADVLEALGFAIDLPPSATEELFRQTGFAFLFAPMYHPSMKA
VAHVRRELGIRTIFNMLGPLLNPAGVKRQLVGVFEPELMDLYGTVLLATGCRHSLIVHGETETGAAFDEPSISGPTHILE
LHEGVMARHIVHPEDFGFIRCPIEDLAGGNREENAIIIRNILDGSATRAKTEAALYAAAMTCYVSGKASCIDEGVCMASD
SLESGQASCKFTAILQLNRELSGKHKALIN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=333, Percent_Identity=33.6336336336336, Blast_Score=168, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6320561, Length=346, Percent_Identity=29.1907514450867, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_CHLPD (A1BE13)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911064.1
- ProteinModelPortal:   A1BE13
- SMR:   A1BE13
- STRING:   A1BE13
- GeneID:   4569179
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0584
- NMPDR:   fig|290317.7.peg.612
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37237; Mature: 37106

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKKLLNMLMAGKDLAREEMTLCMNNIMDGAFSDIVLAALLALLQKKGVTADEAAGAYA
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SIMARATLCKLDEDAVDTCGTGGDNTGTFNISTAAAIIACGAGVSIAKHGNRSMTSQCGS
HHHHHHHHHHCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCEEHHCCCCHHHHHCCC
ADVLEALGFAIDLPPSATEELFRQTGFAFLFAPMYHPSMKAVAHVRRELGIRTIFNMLGP
HHHHHHHCCEEECCCCHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLNPAGVKRQLVGVFEPELMDLYGTVLLATGCRHSLIVHGETETGAAFDEPSISGPTHIL
HCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
ELHEGVMARHIVHPEDFGFIRCPIEDLAGGNREENAIIIRNILDGSATRAKTEAALYAAA
HHHHHHHHHHCCCCCCCCEEECCHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
MTCYVSGKASCIDEGVCMASDSLESGQASCKFTAILQLNRELSGKHKALIN
HHHHCCCCHHHHHCCCEECCCCCCCCCCCEEEEHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
PQKKLLNMLMAGKDLAREEMTLCMNNIMDGAFSDIVLAALLALLQKKGVTADEAAGAYA
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SIMARATLCKLDEDAVDTCGTGGDNTGTFNISTAAAIIACGAGVSIAKHGNRSMTSQCGS
HHHHHHHHHHCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCEEHHCCCCHHHHHCCC
ADVLEALGFAIDLPPSATEELFRQTGFAFLFAPMYHPSMKAVAHVRRELGIRTIFNMLGP
HHHHHHHCCEEECCCCHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLNPAGVKRQLVGVFEPELMDLYGTVLLATGCRHSLIVHGETETGAAFDEPSISGPTHIL
HCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
ELHEGVMARHIVHPEDFGFIRCPIEDLAGGNREENAIIIRNILDGSATRAKTEAALYAAA
HHHHHHHHHHCCCCCCCCEEECCHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
MTCYVSGKASCIDEGVCMASDSLESGQASCKFTAILQLNRELSGKHKALIN
HHHHCCCCHHHHHCCCEECCCCCCCCCCCEEEEHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA