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The map label for this gene is dnaX [H]

Identifier: 119356423

GI number: 119356423

Start: 656942

End: 658108

Strand: Reverse

Name: dnaX [H]

Synonym: Cpha266_0587

Alternate gene names: 119356423

Gene position: 658108-656942 (Counterclockwise)

Preceding gene: 119356424

Following gene: 119356420

Centisome position: 21.0

GC content: 49.79

Gene sequence:

>1167_bases
ATGAGTTGGAACACCATAATCGGTCACAAACAGCAGATCAAGGTTTTGCAGAAAGCGCTGGAAACCGGTCGTCTCGCTCA
TGCCTATCTCTTTACAGGACCTGAAGCCTGCGGAAAAGAATCCGTTGCCTTTGAACTTGCCAGAATACTCAACTGCAGAA
CTGCTGACCCGGTCTCAGGCTCCTGTGAAACCTGCAAAGAGTGCATCTCGCTCAACGCTTTCATGCATCCGAATGTTGAG
TATATCTTTCCTGTAGAGTCCGCACTGCTCGATCCTGGAGACACGGCAAAAAAAGAGAACAAACGCTTTACAGAAGCAAA
GGAGCGTTACGACCTCCTGCTCGAAGAAAAAAAGCAGAACCCTTTTTTCTCTCCTGCCATGGAAAGATCGATGGGCATTC
TCACCGAGCAGGTTATTGCGCTGCAGCACAAGGCCTCGTTTATGCCAAGTCAGGGAACCAGAAAAATCTTTATTCTGTCG
CAGGCCGAAAAGCTTCACCCGTCAGCGGCAAACAAGCTGCTGAAGCTTCTTGAAGAACCCCCGGCACACATTCTTTTTAT
TCTTGTATCTTCGCGACCCGAAGCGGTACTGCCGACTATCCGCTCCCGATGCCAGGTGATCAGGTTCTCAAGAGTAAGCA
GTCGGGAACTTCGCTTATGGCTGCATGAAAACCGTCCTGAAATAACCGATCCCCTTTTGAGCTTTATTGTGAGCTTTTCA
AGGGGCAACCTCAGGCTTGCCTGGGAATTCATCAACAATATCGGTTCCGATACAGCAGAGACAGCCACCATCATCCTGCG
CAACCAGGCAATCGACTACCTTCGCAAAGCGCTTGTGCCGGGAAAACTGCACGAAGCCATTACCGCCTCTGAAGAACAGG
TAAAAAACCTCTCTCGAACTGAACTTACCCTCTTTATTGGCGCTCTCCTGCTTTTCTTTCAGGATGTCAACCACCGACGA
ATCAATCCATCTTTTCAAGGTCTTAACAACCCCGATATCGTCGACTCAATCGACAGATTCGCAAAAAACTTTCCCGATCC
GGATTTTTTCCGCATTTCAACCATCGCTGAAGAGGCCATTCGCGCCATCGAACGAAATGCCAACCCCACGCTTGTCATGG
CCGCCTTCACCGCCGAACTCAAGGGCTTGCTGCAGCGAGTCACATGA

Upstream 100 bases:

>100_bases
ACCGGTTACCGAAGTACTGCAACACAACTACCTTAAAATAGTGCAGACCGGTGAAGATCCCTATAACTGGCTTACCTTTA
TCTGAGCGGGCGGCAGCGGC

Downstream 100 bases:

>100_bases
AACCGGTAGTCCCCCTTTTTTCTGAATCCTGCTTGCCTGTTTCTCCCGATTCTATCCCGGTAGTCGAGTCGAGCCAGTTA
AGATAACCGGGCAATCCTGC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSWNTIIGHKQQIKVLQKALETGRLAHAYLFTGPEACGKESVAFELARILNCRTADPVSGSCETCKECISLNAFMHPNVE
YIFPVESALLDPGDTAKKENKRFTEAKERYDLLLEEKKQNPFFSPAMERSMGILTEQVIALQHKASFMPSQGTRKIFILS
QAEKLHPSAANKLLKLLEEPPAHILFILVSSRPEAVLPTIRSRCQVIRFSRVSSRELRLWLHENRPEITDPLLSFIVSFS
RGNLRLAWEFINNIGSDTAETATIILRNQAIDYLRKALVPGKLHEAITASEEQVKNLSRTELTLFIGALLLFFQDVNHRR
INPSFQGLNNPDIVDSIDRFAKNFPDPDFFRISTIAEEAIRAIERNANPTLVMAAFTAELKGLLQRVT

Sequences:

>Translated_388_residues
MSWNTIIGHKQQIKVLQKALETGRLAHAYLFTGPEACGKESVAFELARILNCRTADPVSGSCETCKECISLNAFMHPNVE
YIFPVESALLDPGDTAKKENKRFTEAKERYDLLLEEKKQNPFFSPAMERSMGILTEQVIALQHKASFMPSQGTRKIFILS
QAEKLHPSAANKLLKLLEEPPAHILFILVSSRPEAVLPTIRSRCQVIRFSRVSSRELRLWLHENRPEITDPLLSFIVSFS
RGNLRLAWEFINNIGSDTAETATIILRNQAIDYLRKALVPGKLHEAITASEEQVKNLSRTELTLFIGALLLFFQDVNHRR
INPSFQGLNNPDIVDSIDRFAKNFPDPDFFRISTIAEEAIRAIERNANPTLVMAAFTAELKGLLQRVT
>Mature_387_residues
SWNTIIGHKQQIKVLQKALETGRLAHAYLFTGPEACGKESVAFELARILNCRTADPVSGSCETCKECISLNAFMHPNVEY
IFPVESALLDPGDTAKKENKRFTEAKERYDLLLEEKKQNPFFSPAMERSMGILTEQVIALQHKASFMPSQGTRKIFILSQ
AEKLHPSAANKLLKLLEEPPAHILFILVSSRPEAVLPTIRSRCQVIRFSRVSSRELRLWLHENRPEITDPLLSFIVSFSR
GNLRLAWEFINNIGSDTAETATIILRNQAIDYLRKALVPGKLHEAITASEEQVKNLSRTELTLFIGALLLFFQDVNHRRI
NPSFQGLNNPDIVDSIDRFAKNFPDPDFFRISTIAEEAIRAIERNANPTLVMAAFTAELKGLLQRVT

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43840; Mature: 43709

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWNTIIGHKQQIKVLQKALETGRLAHAYLFTGPEACGKESVAFELARILNCRTADPVSG
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCC
SCETCKECISLNAFMHPNVEYIFPVESALLDPGDTAKKENKRFTEAKERYDLLLEEKKQN
CHHHHHHHHHCCCEECCCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFFSPAMERSMGILTEQVIALQHKASFMPSQGTRKIFILSQAEKLHPSAANKLLKLLEEP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHCC
PAHILFILVSSRPEAVLPTIRSRCQVIRFSRVSSRELRLWLHENRPEITDPLLSFIVSFS
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
RGNLRLAWEFINNIGSDTAETATIILRNQAIDYLRKALVPGKLHEAITASEEQVKNLSRT
CCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH
ELTLFIGALLLFFQDVNHRRINPSFQGLNNPDIVDSIDRFAKNFPDPDFFRISTIAEEAI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RAIERNANPTLVMAAFTAELKGLLQRVT
HHHHCCCCCCEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWNTIIGHKQQIKVLQKALETGRLAHAYLFTGPEACGKESVAFELARILNCRTADPVSG
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCC
SCETCKECISLNAFMHPNVEYIFPVESALLDPGDTAKKENKRFTEAKERYDLLLEEKKQN
CHHHHHHHHHCCCEECCCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFFSPAMERSMGILTEQVIALQHKASFMPSQGTRKIFILSQAEKLHPSAANKLLKLLEEP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHCC
PAHILFILVSSRPEAVLPTIRSRCQVIRFSRVSSRELRLWLHENRPEITDPLLSFIVSFS
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
RGNLRLAWEFINNIGSDTAETATIILRNQAIDYLRKALVPGKLHEAITASEEQVKNLSRT
CCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH
ELTLFIGALLLFFQDVNHRRINPSFQGLNNPDIVDSIDRFAKNFPDPDFFRISTIAEEAI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RAIERNANPTLVMAAFTAELKGLLQRVT
HHHHCCCCCCEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]