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The map label for this gene is yacO [H]

Identifier: 119356408

GI number: 119356408

Start: 643595

End: 644353

Strand: Direct

Name: yacO [H]

Synonym: Cpha266_0572

Alternate gene names: 119356408

Gene position: 643595-644353 (Clockwise)

Preceding gene: 119356406

Following gene: 119356409

Centisome position: 20.54

GC content: 49.14

Gene sequence:

>759_bases
ATGGAGAAAGAAAAAGATATGGAGCAGCAGGAAAAAGTTGTTTATGGCAGAAACGCCGTGCTTGAGCTGCTTCTGAAGAA
ACCGGACAGCATTGAGAAAATATATTTTCAGTTTAATACTTCGCATCCGAAACTGAAAGAGATCCTTGTCAGCGCCAGAA
GACAGAAACTGGTTACTGGCAAGGCCCGGCTGGAACGACTCTCCCTTATGGCAGGAACGACAAAACATCAGGGGGTCTGT
GCGCTTGTCAGCGCGGTATCGTATTACACCATTGAAGAGGTGCTTGACAAGCCGAGAAATACCTTCCCTCTGCTGCTGAT
TCTTCAGGGTCTGGAAGATCCGCACAATATCGGTGCAATTATAAGAACCGCTGAGGCTGTTGCTGCCGATGCTGTTTTGC
TGATTGAAGGCAAGGGGTCGCCAGTCAATGCCACGGTGCACAAAGCCTCGGCAGGGGCGCTCTCCCACATGAGAGTGTGC
AAGGTGAAAAGCCTGGTTCGTTGTCTTGAATTTCTTCACGAGAGAAAATTTCTCATTATCGCTGCCGATATGGATGCCGA
GATCAATTATACGGATATCGACCTTACCAAAGCGTTGGCGATAGTGCTTGGTGCTGAGGGGAGCGGTCTTGCTCCGGAAG
CTGTAAAATTCTGTGATCATACGGTGCGAATTCCTATGGCAGGCTGCGTGGAGTCTCTTAATGTCAGCGTTACAGCGGGA
GTATTGCTTTATGAAGCAATGCGCCAGCGTCTTGCATAG

Upstream 100 bases:

>100_bases
GAGTAGTTCACCTGAGATCCGGCATGGCACGCCTTGCGCTGTCCGCATTTGATTTCAGTCTTTTGCTGCAAACAGTTAGA
TGATCAGAGAGGCTTGGTTT

Downstream 100 bases:

>100_bases
TGATTATTTCGTTCATTTTCTGATTTCCTCAACAGCAGTAATTTCGCCGCTTGTTTCAGCTCTTTAAAAAAAATGTTACC
TTCAGATTCACTTTTGTTCC

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEKEKDMEQQEKVVYGRNAVLELLLKKPDSIEKIYFQFNTSHPKLKEILVSARRQKLVTGKARLERLSLMAGTTKHQGVC
ALVSAVSYYTIEEVLDKPRNTFPLLLILQGLEDPHNIGAIIRTAEAVAADAVLLIEGKGSPVNATVHKASAGALSHMRVC
KVKSLVRCLEFLHERKFLIIAADMDAEINYTDIDLTKALAIVLGAEGSGLAPEAVKFCDHTVRIPMAGCVESLNVSVTAG
VLLYEAMRQRLA

Sequences:

>Translated_252_residues
MEKEKDMEQQEKVVYGRNAVLELLLKKPDSIEKIYFQFNTSHPKLKEILVSARRQKLVTGKARLERLSLMAGTTKHQGVC
ALVSAVSYYTIEEVLDKPRNTFPLLLILQGLEDPHNIGAIIRTAEAVAADAVLLIEGKGSPVNATVHKASAGALSHMRVC
KVKSLVRCLEFLHERKFLIIAADMDAEINYTDIDLTKALAIVLGAEGSGLAPEAVKFCDHTVRIPMAGCVESLNVSVTAG
VLLYEAMRQRLA
>Mature_252_residues
MEKEKDMEQQEKVVYGRNAVLELLLKKPDSIEKIYFQFNTSHPKLKEILVSARRQKLVTGKARLERLSLMAGTTKHQGVC
ALVSAVSYYTIEEVLDKPRNTFPLLLILQGLEDPHNIGAIIRTAEAVAADAVLLIEGKGSPVNATVHKASAGALSHMRVC
KVKSLVRCLEFLHERKFLIIAADMDAEINYTDIDLTKALAIVLGAEGSGLAPEAVKFCDHTVRIPMAGCVESLNVSVTAG
VLLYEAMRQRLA

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=258, Percent_Identity=27.906976744186, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI1790623, Length=240, Percent_Identity=32.9166666666667, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790083, Length=153, Percent_Identity=35.2941176470588, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788935, Length=252, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555908, Length=261, Percent_Identity=28.3524904214559, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27679; Mature: 27679

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEKDMEQQEKVVYGRNAVLELLLKKPDSIEKIYFQFNTSHPKLKEILVSARRQKLVTG
CCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
KARLERLSLMAGTTKHQGVCALVSAVSYYTIEEVLDKPRNTFPLLLILQGLEDPHNIGAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHHHH
IRTAEAVAADAVLLIEGKGSPVNATVHKASAGALSHMRVCKVKSLVRCLEFLHERKFLII
HHHHHHHHHCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AADMDAEINYTDIDLTKALAIVLGAEGSGLAPEAVKFCDHTVRIPMAGCVESLNVSVTAG
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEECCHHHHHHHCCCHHHHH
VLLYEAMRQRLA
HHHHHHHHHHCC
>Mature Secondary Structure
MEKEKDMEQQEKVVYGRNAVLELLLKKPDSIEKIYFQFNTSHPKLKEILVSARRQKLVTG
CCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
KARLERLSLMAGTTKHQGVCALVSAVSYYTIEEVLDKPRNTFPLLLILQGLEDPHNIGAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHHHH
IRTAEAVAADAVLLIEGKGSPVNATVHKASAGALSHMRVCKVKSLVRCLEFLHERKFLII
HHHHHHHHHCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AADMDAEINYTDIDLTKALAIVLGAEGSGLAPEAVKFCDHTVRIPMAGCVESLNVSVTAG
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEECCHHHHHHHCCCHHHHH
VLLYEAMRQRLA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]