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The map label for this gene is grsB [H]

Identifier: 119356383

GI number: 119356383

Start: 601546

End: 608001

Strand: Direct

Name: grsB [H]

Synonym: Cpha266_0546

Alternate gene names: 119356383

Gene position: 601546-608001 (Clockwise)

Preceding gene: 119356382

Following gene: 119356384

Centisome position: 19.19

GC content: 45.54

Gene sequence:

>6456_bases
ATGAAAGAGGGAATCACGACGGTTGAAAACAGGTATGGCGTAGAAACGCCACTTCACTATTACGATATTTCACATTGCCT
GCATGAGCTGTTCAAAAAACAGGCATCTCTCAATGCGGATAATCCGGCTGTTATTGATGGGACTGGTTCGCTGACATACA
GGGTACTGGATGAAGAGGCTGACAATATTGCGCAAGCGATAGTGCAGAGGGGAATCAATCGGGGATCGTTCATCGGGTTG
TGCACAACCCGTTCCTCACAGGTGATTTCCGGTATGCTCGGGATTCTGAAGGCTGAATGTGCTTATGTTCATCTCGACCC
TGAATATCCATCCGATCGTCTCGGATATATTATTGATGATGCCGGTATTTCGTTAATTCTGACTCAACAGCGTTTCACGC
AAACGTTTTCGTTCTGCTTGCCATCGTTGTTGCTGTTTATGGACTGCGATCAGCCAGAATCATACACCGCTTCTATACCT
TTTTCTCCAGTGGAAGCATCTGTTTCAGGCGATCCGGCTTATGTGATCTACACGTCTGGTACAACAGGAAAGCCCAAGGG
TGTATGTTGTCATCACAAGGGTGTTGTCAATCTGCTCGATGAGTTTCAACAGCGTCGGTATCTTGGGTCGGAGGATAGAT
GCAGTTGGTGGACAAATCTGAATTTTGACGTTTCTGTTTACGAAATATTTTCATCGCTGCTTGCTGGCTCAGCACTTCTG
ATTGTTCCCGAGTCTGTCCGCATTGACGGCCATGCTTTTATGGATTGGCTGCATGTCAATGATATTACAAGCGCCTATCT
TCCACCTATGATGGTTGCGGATTTTTTGGAATGGGTAGAGCGAAATCCCGGCAAGAGTCGTATGCGCCGTTTATTGACTG
GTGTAGAGCCCATACCTGAAAATCTGTTGCTGAACATTCAGCGATGTGTTCCCCAATTGACCATCATCAATGGATACGGG
CCGACTGAAACCACTATTTGCGCAACCCTTTATACCGTTAACTCCGCAAGTCATCACCACGAAACCACTCCTGTTGGCAA
AGCGGTGCAGAATATGCATCTCCATCTTCTTGATGAAGCGGGTGATCCGGTTGCTGCTGGCGAAACAGGTGAGGTGTACA
TTGGCGGTGTTGGTGTGTCACGAGGGTATCTGAACCAGCCGGAGCTGAATGAGTGCCTGTTTATTTCTGATCCGTGTTAT
AAGGAAGAGGGATATCGCATGTATCGTACCGGTGATCTTGCCGTTTTTCTTCCCGACGGAGAGCTTGCTTTTGTCGGAAG
AAAAGATTTTCAGGTCAAGTACATGGGTTACAGGATTGAGCTTGGAGAGATCGAAATGGTATTGAAAAGTCATGCTGCGA
TCAGAGATGCTGTTGTGATGCTTCGGGAAGACGATCCCGGTTTGAAAAAAATAGTGGCATATTGTGTTTTGGAAATTTCC
GGGAACGTCAGTCCGAAGGAGCTTCAATTGTTCGCCGGGCGGTTGCTTCCTGCCTATATGATTCCGGCTGTTTTTGTTTT
TCTTAAAAAAATTCCGATGACTCCAAATGGCAAGTCAGACAGAAATGCCTTGCCTCCTCCCGGAAAAGAGAGTTTTCTGG
CTGGAAAGGATGACGGTTATACCGCTCCGGAGAGTGTTATGGAACGGGATGTTGCTGCTGTTTTATCCGGTATTCTTGGT
ATAAGCGCTATCGGTGTCGATGACAATCTCTTCTCTCTTGGCGCTCATTCGCTTATGGCTACCAGACTTTGTTCGCAAAT
CCGCATGCGCTGGAATGTCAACATCCCTCTTGCCTTTGTTTTTGAAAATCCTACAGTAAAACAGATTGCCGATGAGATAG
TTCGAAAAGAGAGAATTGGTGATGTTCCTTGCCGTATAACAGCATCTGATGCTCATCGTACAGTTTTCCCTGTTTCATTG
ATTCAGAAAGGGCTCTGGCTCTTTCAACAATTTCAGGAAGAAGGGACATTATTCAACATTCCTGTAGTTGTGTACTTTTC
CGGCGCCATTCAGGAGCAACTGATCAAAAAGTCTTTTGATTTTCTGATCGACAGGCATGAGTGTCTGCGCACCGTCTTTG
AGCTTGAGGGCGAAGAGCTTGTTCAAAGAGTATTGCCGGCCATGCAAGTTGAGCTGATGGTGAAGGATCTTTCGGGTTGT
AACCAGGATACGAAATTCGCAGAGCTTGATAGAATCAGAAAAGAAGAGGGCCTTCATCGGTTTGAACTCGACAAGGGGCC
GCTTATAAAGCTTCATCTCGTCATATTGGGCGAAAGTGCGACTCATCTGTTTATAACTTTTCATCATCTGATCATAGATG
GATGGGGAGCATCTGTTTTATTCAGGGAGTTGGCTGCCAGTTATGATGCTTTTTCCAGGGGAAATATGCCTGCGCTGCCA
GATAAAAAGATCTCTTTTGGTGATTTTTGTCTGTGGCAGCTTGAGCGAATAAAAAGCGCACGGCTTTCAATGCAGATTCA
GTACTGGATTGAACAATTAAAAGGATGTTCATTCATACAGAATATTCCGCACGATTATTCGAGGCCATCAATGCCTTCTT
TTTCCGGAGCAAGGTGCGCATTTTCCTTTTCTCCTGAAATCACGAAGGCCCTGAATGAATATTGCCTGCGGAACAACTGC
ACCATGTTCATGTATTTAATGACGGTCTTTCAGATTTTTATCCAGAGATATTCCGGAAGGAGTGAGATTGTAACAGGAAC
GACCATTGCCAATCGCAATCTGTCGGATACAGAAAATATTGTGGGCTTGCTGGCAAACAGTCTGGCGATCAGAACTGATT
TCTCCGGTGATCCGAAGTTTACAGAACTTCTCATGCAGGTCAGAAAAGTTTCGTTGGAGGCATTTGACAATCAGGACGTG
CCGTTTGAGATCGTTGTTGAAAACGTTGTTCAAAAGCGGGAAAGAAGTTACCATCCGGTTTTTCAAAATCTTTTCATTTT
TCAGAATACGCCACCGCCCTTCTTGCATGCCGGTGATATGGATTTTGTTTATGAAGAGATTGGAAACGAAACGGCCAAGC
TCGATCTGTTACTGAATGTGGAGTTCCGAAAAGAGTCTCTTTTCTGCTGGATTGAATACAATACCTGCCTTTTTAATGCT
GATACTATTGAGAGAGTTGCGAGGGATTATATCTGGATTGCGAGTCACGCACTTCATGAAACCGGTGATCCGGTTTCATC
CTGGCATTTTCCCTCCATCCCGGCCAGAAATTATTATGCAACGAAAGATAATCCGTTAGCGCTTTCCTGCTGCCATTATC
TTTTTGAGCTCCAGGCAGAAAGGACGCCGGACAATATCGCAGTATGCTGTGATGATGTTCAGATGACCTTCCGTGAACTT
AATAAAAAAGCAAATCATCTGGCACATCGGCTCATTCAAAGAGGAGTCGGGCCCGATATTCCTGTTGGTCTATGTTTAAC
CCGAAGCGTATACCTGGCAGTCGGAATACTTGGTATTTTAAAAGCAGGAGGGAGCTACGTTCCTCTTGACAGTCAATATC
CGGAAGAGCGCATCAGGTATATGGCTCATGATTCCGGTATAAGGCTTGCCGTTACCGACGAAGCTTCTGCACACGTCTTG
TCATTCGACAGGGAGATGCTCCTTGTGTTGCTTGACAAGTCAGACGCAGTTGAATCAGAGCACTCCTGCGACAATCCTGT
TTTCCGGGCAGGAGCTGAAAATACAGCCTACATCATGTATACCTCAGGAACTTCCGGGAGACCTAAAGGTGTCATGGTTC
CTCATAGAGGGGTCTCAAATCTTGCTGTATCAGCGGTAAATAATTACGCTCTGAAAAGTAGCGACAGAGTGCTTCAATTT
TTTTCTGTAAGTTTTGACGGATCTGTTGAAGAGATATTCATGACCCTTGCCGTCGGAGCAACGCTGGTAATAAGAACATT
TAATGCTGCAATTTCGGTAACTGATTTTTTATTCCATCTTGAGAAAAATGAGATTACCGTACTTGATCTCCCGACTGCTT
TCTGGAAAGAGCTTGTTCATGGAGTTTCGAGAACCGGCATAAAGATACCGAATTCTCTCAGACTGGTTATTATCGGCGGG
GAGCAGGCATCGGTGACAGATTTTCAAAAGTGGCAAAAAGTTTGCGGTGGCAGGGTCAGGCTTATCAATACGTATGGGCC
TACCGAGTGTTCGGCGGTTTCGGTTTTTTCTGAACCAGAGAAGATTAATTGTTCATATGATTTTAACCGGGGGCTACCCA
TCGGGAGGCCTATGGACAATACAACACTTTATGTTGTTGATGAGCATTGTTGCCTTGTTCCATTTGGCATGCCCGGTGAA
CTGCTCATTGGAGGCGCTGGTGTGGCTAAAGGGTACCTTAATCTTTCTCTGTTAACGGAGGATCGTTTTATTGATGACGT
TTTTCAGGAAAGCGAGCCAAAAGGGAGACTCTATAGAACAGGGGATATCGTCCGCAGCCTTTCTGACGGCAATCTCCAGT
TTCTCGGAAGAAAAGACAATCAGGTAAAAATACGGGGGTTCAGGATAGAGCCAGGCGAGATTGAGTCGGTACTTAATCAG
CATGAGCTGATAAAACAATCCGTGGTCATCGACCTGACAAATGATCAGGGAGAAACCGCTCTCGTTGGTTACTTCGTTAC
AGAGAAAAATGCTCTGTCTTCTTCAGAGTTAAGGCACTACCTGGCACAAAAAATGCCAGAGTATATGGTGCCATCTTATT
TTGTGCCTATCAAGAAAGTTCCGCTGCTTCCTAACGGCAAGATTGACAGAAGCGCACTTCCTGTTCCGGATACTGTCGTT
GAAAAAAAAGCCACCTATGTCGGGCCGAGGGATGAAACCGAAAAAACACTTGTCGAAATCTGGCAGGAAGTGCTTGGGGT
TCATCCAATAGGAGTTACAGATGATTTTTTTGAACTTGGAGGTCACTCTCTTTTGGCTGTGAGATTGTGCTCCCAAATTC
AGGAAAAGGTCAACAAAAAGGTTACCCTGTCAGGACTTTTTCAGAGCCTGACGATTGAAAAGCTTGCCCGCACGATAACC
GATGAGGTTTGGGTCCCCGAATCATCTCCTGCTGTTTGTATCCAGTGCGTTGATTTCGGAAAATCTCTTCCCCCGTTGTT
TTTTATTCATATTCTTGGTACCGGATTGAAGTTTTGTCGGCCGATGGTCAAGTATTTGTCCCCTGAACTGCCTGTCTATG
GACTTTCAGTTCATTTGAATGAAAAAGATCATTTCGAAGAATTCAGTGTGGAGGAGCTGGCAACGCGCTATGTTCGTGAA
GTGAGACGGATTTATCCGCAAGGGCCATTTTTGTTTGCAGGAATCTCTTTTGGAGGCCTTATCGCTTTTGAAATGGCAAG
GAAGATGAGTGAAGATGGAGAGGATATTCGTATGGTTGCGCTTATTGACAGCATTTTGCCGGAAGCGTTTCATAAAATGA
CAGGAAAAGAGGGTGCGCATGCGCATCGTGAAAAATTCAGAAGCGAGGGAGTCTCCTATTTGATCAGGAAAGTACTTGAA
AGAGCGCGGCATGAAGGGTTTGTTATGAGGGAAAAATCCAGCCACTGCTATTCTAAAATTCTTTTGCAGTACTATATGGT
CAGGGATAGAGTCGACCGGATGCCAGTCTCTCTCTATGAATTTGCTGCAAGGCTTCAGAATGACGATGCCTTGCAGAAGT
ATCATCCGAAAATTTATACCGGAAAAGTTACTCTTTTCAAAAGTCGGGAAAGATTTTACGGCGTCAGTTTTATCCAGGAT
CCTCTGTCAGGATGGGGAGCGTTTTCGTCAGGTGGCGTTGAGGTTATTGATTGTCCCGGAGACCATCTCGGAATGCTTGC
AGATCCTCATGTGGAAACATTGGGCATGAAGCTGATGCAATCAATTGAAACGTGCCTGCATATGGCCAGGCCGATCGCAA
CATCGCAAACTGGCGAGGTAGTCATTCGTTCTGTCAAAAGAGGGGAAAGCCGGTTATTCAGAGATATTTCATTGCGCTCG
ATCAGAGAATCTCCCGATGCATTTGTAGCCACACTCGATCAAGTTCAGCATGAACCGCTGACTTACTGGGAACAGTTACT
TGATTTTATTGTGGATTCGCCACTCGATACGATTTTTCTGGCATGTATCGATCAGCGGTGTATCGGGTTTGCTGCCGCGA
GAATATATTCGAATGATCCCTATCTGACGGAACTGAGATGGATGTGGGTTGATCGCGATTTCAGGGGAAAAGGATTGGGC
GGGAGTCTTCTTGAAAAGGTTATCGAGTGGGCTCAGTCCAGAGGATCTCAAAAAATCAATCTCTGGGTTTCCGAAAGCCA
GAACTCAGCCATTCAGCTTTATACATCGAAGGGCTTTGTCGATACCGGAGATCGGGGTTTTCTCCGTCCGGGATCGGCAT
TACACGCAAGAAAGATGATTCGCGATAATGCTGATTATTTGCGTCATGGAGGATGA

Upstream 100 bases:

>100_bases
TAACCAATTCGATCACGATCTTTTTGCTGCGTTTCGTCGGCAAAGCATAACGTAGTACAGGGCTGTGAGAAGTGCTTTCG
ATAGCTTATTCGGGACGCAT

Downstream 100 bases:

>100_bases
AAAATGAACATGACTCATCAGCGTGTATATGTCTGGCAAATAAATATCGAAGTATTCGAGGAGAACGCGGATGCATTTTT
TTCTCTTTTGTCTTCGGATG

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Gramicidin S synthase II; ATP-dependent proline adenylase; ProA; Proline activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2151; Mature: 2151

Protein sequence:

>2151_residues
MKEGITTVENRYGVETPLHYYDISHCLHELFKKQASLNADNPAVIDGTGSLTYRVLDEEADNIAQAIVQRGINRGSFIGL
CTTRSSQVISGMLGILKAECAYVHLDPEYPSDRLGYIIDDAGISLILTQQRFTQTFSFCLPSLLLFMDCDQPESYTASIP
FSPVEASVSGDPAYVIYTSGTTGKPKGVCCHHKGVVNLLDEFQQRRYLGSEDRCSWWTNLNFDVSVYEIFSSLLAGSALL
IVPESVRIDGHAFMDWLHVNDITSAYLPPMMVADFLEWVERNPGKSRMRRLLTGVEPIPENLLLNIQRCVPQLTIINGYG
PTETTICATLYTVNSASHHHETTPVGKAVQNMHLHLLDEAGDPVAAGETGEVYIGGVGVSRGYLNQPELNECLFISDPCY
KEEGYRMYRTGDLAVFLPDGELAFVGRKDFQVKYMGYRIELGEIEMVLKSHAAIRDAVVMLREDDPGLKKIVAYCVLEIS
GNVSPKELQLFAGRLLPAYMIPAVFVFLKKIPMTPNGKSDRNALPPPGKESFLAGKDDGYTAPESVMERDVAAVLSGILG
ISAIGVDDNLFSLGAHSLMATRLCSQIRMRWNVNIPLAFVFENPTVKQIADEIVRKERIGDVPCRITASDAHRTVFPVSL
IQKGLWLFQQFQEEGTLFNIPVVVYFSGAIQEQLIKKSFDFLIDRHECLRTVFELEGEELVQRVLPAMQVELMVKDLSGC
NQDTKFAELDRIRKEEGLHRFELDKGPLIKLHLVILGESATHLFITFHHLIIDGWGASVLFRELAASYDAFSRGNMPALP
DKKISFGDFCLWQLERIKSARLSMQIQYWIEQLKGCSFIQNIPHDYSRPSMPSFSGARCAFSFSPEITKALNEYCLRNNC
TMFMYLMTVFQIFIQRYSGRSEIVTGTTIANRNLSDTENIVGLLANSLAIRTDFSGDPKFTELLMQVRKVSLEAFDNQDV
PFEIVVENVVQKRERSYHPVFQNLFIFQNTPPPFLHAGDMDFVYEEIGNETAKLDLLLNVEFRKESLFCWIEYNTCLFNA
DTIERVARDYIWIASHALHETGDPVSSWHFPSIPARNYYATKDNPLALSCCHYLFELQAERTPDNIAVCCDDVQMTFREL
NKKANHLAHRLIQRGVGPDIPVGLCLTRSVYLAVGILGILKAGGSYVPLDSQYPEERIRYMAHDSGIRLAVTDEASAHVL
SFDREMLLVLLDKSDAVESEHSCDNPVFRAGAENTAYIMYTSGTSGRPKGVMVPHRGVSNLAVSAVNNYALKSSDRVLQF
FSVSFDGSVEEIFMTLAVGATLVIRTFNAAISVTDFLFHLEKNEITVLDLPTAFWKELVHGVSRTGIKIPNSLRLVIIGG
EQASVTDFQKWQKVCGGRVRLINTYGPTECSAVSVFSEPEKINCSYDFNRGLPIGRPMDNTTLYVVDEHCCLVPFGMPGE
LLIGGAGVAKGYLNLSLLTEDRFIDDVFQESEPKGRLYRTGDIVRSLSDGNLQFLGRKDNQVKIRGFRIEPGEIESVLNQ
HELIKQSVVIDLTNDQGETALVGYFVTEKNALSSSELRHYLAQKMPEYMVPSYFVPIKKVPLLPNGKIDRSALPVPDTVV
EKKATYVGPRDETEKTLVEIWQEVLGVHPIGVTDDFFELGGHSLLAVRLCSQIQEKVNKKVTLSGLFQSLTIEKLARTIT
DEVWVPESSPAVCIQCVDFGKSLPPLFFIHILGTGLKFCRPMVKYLSPELPVYGLSVHLNEKDHFEEFSVEELATRYVRE
VRRIYPQGPFLFAGISFGGLIAFEMARKMSEDGEDIRMVALIDSILPEAFHKMTGKEGAHAHREKFRSEGVSYLIRKVLE
RARHEGFVMREKSSHCYSKILLQYYMVRDRVDRMPVSLYEFAARLQNDDALQKYHPKIYTGKVTLFKSRERFYGVSFIQD
PLSGWGAFSSGGVEVIDCPGDHLGMLADPHVETLGMKLMQSIETCLHMARPIATSQTGEVVIRSVKRGESRLFRDISLRS
IRESPDAFVATLDQVQHEPLTYWEQLLDFIVDSPLDTIFLACIDQRCIGFAAARIYSNDPYLTELRWMWVDRDFRGKGLG
GSLLEKVIEWAQSRGSQKINLWVSESQNSAIQLYTSKGFVDTGDRGFLRPGSALHARKMIRDNADYLRHGG

Sequences:

>Translated_2151_residues
MKEGITTVENRYGVETPLHYYDISHCLHELFKKQASLNADNPAVIDGTGSLTYRVLDEEADNIAQAIVQRGINRGSFIGL
CTTRSSQVISGMLGILKAECAYVHLDPEYPSDRLGYIIDDAGISLILTQQRFTQTFSFCLPSLLLFMDCDQPESYTASIP
FSPVEASVSGDPAYVIYTSGTTGKPKGVCCHHKGVVNLLDEFQQRRYLGSEDRCSWWTNLNFDVSVYEIFSSLLAGSALL
IVPESVRIDGHAFMDWLHVNDITSAYLPPMMVADFLEWVERNPGKSRMRRLLTGVEPIPENLLLNIQRCVPQLTIINGYG
PTETTICATLYTVNSASHHHETTPVGKAVQNMHLHLLDEAGDPVAAGETGEVYIGGVGVSRGYLNQPELNECLFISDPCY
KEEGYRMYRTGDLAVFLPDGELAFVGRKDFQVKYMGYRIELGEIEMVLKSHAAIRDAVVMLREDDPGLKKIVAYCVLEIS
GNVSPKELQLFAGRLLPAYMIPAVFVFLKKIPMTPNGKSDRNALPPPGKESFLAGKDDGYTAPESVMERDVAAVLSGILG
ISAIGVDDNLFSLGAHSLMATRLCSQIRMRWNVNIPLAFVFENPTVKQIADEIVRKERIGDVPCRITASDAHRTVFPVSL
IQKGLWLFQQFQEEGTLFNIPVVVYFSGAIQEQLIKKSFDFLIDRHECLRTVFELEGEELVQRVLPAMQVELMVKDLSGC
NQDTKFAELDRIRKEEGLHRFELDKGPLIKLHLVILGESATHLFITFHHLIIDGWGASVLFRELAASYDAFSRGNMPALP
DKKISFGDFCLWQLERIKSARLSMQIQYWIEQLKGCSFIQNIPHDYSRPSMPSFSGARCAFSFSPEITKALNEYCLRNNC
TMFMYLMTVFQIFIQRYSGRSEIVTGTTIANRNLSDTENIVGLLANSLAIRTDFSGDPKFTELLMQVRKVSLEAFDNQDV
PFEIVVENVVQKRERSYHPVFQNLFIFQNTPPPFLHAGDMDFVYEEIGNETAKLDLLLNVEFRKESLFCWIEYNTCLFNA
DTIERVARDYIWIASHALHETGDPVSSWHFPSIPARNYYATKDNPLALSCCHYLFELQAERTPDNIAVCCDDVQMTFREL
NKKANHLAHRLIQRGVGPDIPVGLCLTRSVYLAVGILGILKAGGSYVPLDSQYPEERIRYMAHDSGIRLAVTDEASAHVL
SFDREMLLVLLDKSDAVESEHSCDNPVFRAGAENTAYIMYTSGTSGRPKGVMVPHRGVSNLAVSAVNNYALKSSDRVLQF
FSVSFDGSVEEIFMTLAVGATLVIRTFNAAISVTDFLFHLEKNEITVLDLPTAFWKELVHGVSRTGIKIPNSLRLVIIGG
EQASVTDFQKWQKVCGGRVRLINTYGPTECSAVSVFSEPEKINCSYDFNRGLPIGRPMDNTTLYVVDEHCCLVPFGMPGE
LLIGGAGVAKGYLNLSLLTEDRFIDDVFQESEPKGRLYRTGDIVRSLSDGNLQFLGRKDNQVKIRGFRIEPGEIESVLNQ
HELIKQSVVIDLTNDQGETALVGYFVTEKNALSSSELRHYLAQKMPEYMVPSYFVPIKKVPLLPNGKIDRSALPVPDTVV
EKKATYVGPRDETEKTLVEIWQEVLGVHPIGVTDDFFELGGHSLLAVRLCSQIQEKVNKKVTLSGLFQSLTIEKLARTIT
DEVWVPESSPAVCIQCVDFGKSLPPLFFIHILGTGLKFCRPMVKYLSPELPVYGLSVHLNEKDHFEEFSVEELATRYVRE
VRRIYPQGPFLFAGISFGGLIAFEMARKMSEDGEDIRMVALIDSILPEAFHKMTGKEGAHAHREKFRSEGVSYLIRKVLE
RARHEGFVMREKSSHCYSKILLQYYMVRDRVDRMPVSLYEFAARLQNDDALQKYHPKIYTGKVTLFKSRERFYGVSFIQD
PLSGWGAFSSGGVEVIDCPGDHLGMLADPHVETLGMKLMQSIETCLHMARPIATSQTGEVVIRSVKRGESRLFRDISLRS
IRESPDAFVATLDQVQHEPLTYWEQLLDFIVDSPLDTIFLACIDQRCIGFAAARIYSNDPYLTELRWMWVDRDFRGKGLG
GSLLEKVIEWAQSRGSQKINLWVSESQNSAIQLYTSKGFVDTGDRGFLRPGSALHARKMIRDNADYLRHGG
>Mature_2151_residues
MKEGITTVENRYGVETPLHYYDISHCLHELFKKQASLNADNPAVIDGTGSLTYRVLDEEADNIAQAIVQRGINRGSFIGL
CTTRSSQVISGMLGILKAECAYVHLDPEYPSDRLGYIIDDAGISLILTQQRFTQTFSFCLPSLLLFMDCDQPESYTASIP
FSPVEASVSGDPAYVIYTSGTTGKPKGVCCHHKGVVNLLDEFQQRRYLGSEDRCSWWTNLNFDVSVYEIFSSLLAGSALL
IVPESVRIDGHAFMDWLHVNDITSAYLPPMMVADFLEWVERNPGKSRMRRLLTGVEPIPENLLLNIQRCVPQLTIINGYG
PTETTICATLYTVNSASHHHETTPVGKAVQNMHLHLLDEAGDPVAAGETGEVYIGGVGVSRGYLNQPELNECLFISDPCY
KEEGYRMYRTGDLAVFLPDGELAFVGRKDFQVKYMGYRIELGEIEMVLKSHAAIRDAVVMLREDDPGLKKIVAYCVLEIS
GNVSPKELQLFAGRLLPAYMIPAVFVFLKKIPMTPNGKSDRNALPPPGKESFLAGKDDGYTAPESVMERDVAAVLSGILG
ISAIGVDDNLFSLGAHSLMATRLCSQIRMRWNVNIPLAFVFENPTVKQIADEIVRKERIGDVPCRITASDAHRTVFPVSL
IQKGLWLFQQFQEEGTLFNIPVVVYFSGAIQEQLIKKSFDFLIDRHECLRTVFELEGEELVQRVLPAMQVELMVKDLSGC
NQDTKFAELDRIRKEEGLHRFELDKGPLIKLHLVILGESATHLFITFHHLIIDGWGASVLFRELAASYDAFSRGNMPALP
DKKISFGDFCLWQLERIKSARLSMQIQYWIEQLKGCSFIQNIPHDYSRPSMPSFSGARCAFSFSPEITKALNEYCLRNNC
TMFMYLMTVFQIFIQRYSGRSEIVTGTTIANRNLSDTENIVGLLANSLAIRTDFSGDPKFTELLMQVRKVSLEAFDNQDV
PFEIVVENVVQKRERSYHPVFQNLFIFQNTPPPFLHAGDMDFVYEEIGNETAKLDLLLNVEFRKESLFCWIEYNTCLFNA
DTIERVARDYIWIASHALHETGDPVSSWHFPSIPARNYYATKDNPLALSCCHYLFELQAERTPDNIAVCCDDVQMTFREL
NKKANHLAHRLIQRGVGPDIPVGLCLTRSVYLAVGILGILKAGGSYVPLDSQYPEERIRYMAHDSGIRLAVTDEASAHVL
SFDREMLLVLLDKSDAVESEHSCDNPVFRAGAENTAYIMYTSGTSGRPKGVMVPHRGVSNLAVSAVNNYALKSSDRVLQF
FSVSFDGSVEEIFMTLAVGATLVIRTFNAAISVTDFLFHLEKNEITVLDLPTAFWKELVHGVSRTGIKIPNSLRLVIIGG
EQASVTDFQKWQKVCGGRVRLINTYGPTECSAVSVFSEPEKINCSYDFNRGLPIGRPMDNTTLYVVDEHCCLVPFGMPGE
LLIGGAGVAKGYLNLSLLTEDRFIDDVFQESEPKGRLYRTGDIVRSLSDGNLQFLGRKDNQVKIRGFRIEPGEIESVLNQ
HELIKQSVVIDLTNDQGETALVGYFVTEKNALSSSELRHYLAQKMPEYMVPSYFVPIKKVPLLPNGKIDRSALPVPDTVV
EKKATYVGPRDETEKTLVEIWQEVLGVHPIGVTDDFFELGGHSLLAVRLCSQIQEKVNKKVTLSGLFQSLTIEKLARTIT
DEVWVPESSPAVCIQCVDFGKSLPPLFFIHILGTGLKFCRPMVKYLSPELPVYGLSVHLNEKDHFEEFSVEELATRYVRE
VRRIYPQGPFLFAGISFGGLIAFEMARKMSEDGEDIRMVALIDSILPEAFHKMTGKEGAHAHREKFRSEGVSYLIRKVLE
RARHEGFVMREKSSHCYSKILLQYYMVRDRVDRMPVSLYEFAARLQNDDALQKYHPKIYTGKVTLFKSRERFYGVSFIQD
PLSGWGAFSSGGVEVIDCPGDHLGMLADPHVETLGMKLMQSIETCLHMARPIATSQTGEVVIRSVKRGESRLFRDISLRS
IRESPDAFVATLDQVQHEPLTYWEQLLDFIVDSPLDTIFLACIDQRCIGFAAARIYSNDPYLTELRWMWVDRDFRGKGLG
GSLLEKVIEWAQSRGSQKINLWVSESQNSAIQLYTSKGFVDTGDRGFLRPGSALHARKMIRDNADYLRHGG

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=621, Percent_Identity=25.4428341384863, Blast_Score=134, Evalue=9e-31,
Organism=Homo sapiens, GI187761345, Length=532, Percent_Identity=26.5037593984962, Blast_Score=120, Evalue=2e-26,
Organism=Homo sapiens, GI187761343, Length=532, Percent_Identity=26.5037593984962, Blast_Score=120, Evalue=2e-26,
Organism=Homo sapiens, GI156151445, Length=521, Percent_Identity=22.4568138195777, Blast_Score=93, Evalue=3e-18,
Organism=Homo sapiens, GI38505220, Length=512, Percent_Identity=24.0234375, Blast_Score=92, Evalue=8e-18,
Organism=Homo sapiens, GI28416953, Length=550, Percent_Identity=22.5454545454545, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI122937307, Length=523, Percent_Identity=24.0917782026769, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI157311624, Length=518, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=6e-16,
Organism=Homo sapiens, GI157311622, Length=518, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=6e-16,
Organism=Homo sapiens, GI58082049, Length=518, Percent_Identity=23.7451737451737, Blast_Score=83, Evalue=4e-15,
Organism=Homo sapiens, GI115511026, Length=518, Percent_Identity=22.5868725868726, Blast_Score=80, Evalue=2e-14,
Organism=Escherichia coli, GI1786801, Length=723, Percent_Identity=32.088520055325, Blast_Score=305, Evalue=3e-83,
Organism=Escherichia coli, GI145693145, Length=519, Percent_Identity=25.4335260115607, Blast_Score=103, Evalue=9e-23,
Organism=Escherichia coli, GI1788107, Length=560, Percent_Identity=24.6428571428571, Blast_Score=101, Evalue=5e-22,
Organism=Escherichia coli, GI1786810, Length=528, Percent_Identity=22.9166666666667, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17550940, Length=1271, Percent_Identity=22.5019669551534, Blast_Score=209, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17556356, Length=566, Percent_Identity=28.4452296819788, Blast_Score=156, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71994703, Length=520, Percent_Identity=23.0769230769231, Blast_Score=102, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994694, Length=520, Percent_Identity=23.0769230769231, Blast_Score=102, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994690, Length=520, Percent_Identity=23.0769230769231, Blast_Score=101, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=524, Percent_Identity=22.3282442748092, Blast_Score=94, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32564420, Length=449, Percent_Identity=25.6124721603563, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32564422, Length=449, Percent_Identity=25.6124721603563, Blast_Score=91, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17531443, Length=557, Percent_Identity=22.0825852782765, Blast_Score=88, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=494, Percent_Identity=22.8744939271255, Blast_Score=88, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560308, Length=373, Percent_Identity=27.0777479892761, Blast_Score=79, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=957, Percent_Identity=22.9885057471264, Blast_Score=222, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6319699, Length=368, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648676, Length=653, Percent_Identity=26.4931087289433, Blast_Score=188, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24581924, Length=572, Percent_Identity=23.4265734265734, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582852, Length=626, Percent_Identity=25.7188498402556, Blast_Score=93, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859661, Length=529, Percent_Identity=23.4404536862004, Blast_Score=86, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355181, Length=382, Percent_Identity=22.5130890052356, Blast_Score=83, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653035, Length=480, Percent_Identity=24.1666666666667, Blast_Score=77, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161076582, Length=502, Percent_Identity=23.7051792828685, Blast_Score=75, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356947, Length=481, Percent_Identity=19.95841995842, Blast_Score=74, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648260, Length=484, Percent_Identity=23.7603305785124, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 241708; Mature: 241708

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEGITTVENRYGVETPLHYYDISHCLHELFKKQASLNADNPAVIDGTGSLTYRVLDEEA
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECHHH
DNIAQAIVQRGINRGSFIGLCTTRSSQVISGMLGILKAECAYVHLDPEYPSDRLGYIIDD
HHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEC
AGISLILTQQRFTQTFSFCLPSLLLFMDCDQPESYTASIPFSPVEASVSGDPAYVIYTSG
CCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECC
TTGKPKGVCCHHKGVVNLLDEFQQRRYLGSEDRCSWWTNLNFDVSVYEIFSSLLAGSALL
CCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEE
IVPESVRIDGHAFMDWLHVNDITSAYLPPMMVADFLEWVERNPGKSRMRRLLTGVEPIPE
EECCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
NLLLNIQRCVPQLTIINGYGPTETTICATLYTVNSASHHHETTPVGKAVQNMHLHLLDEA
HHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHEEEEECC
GDPVAAGETGEVYIGGVGVSRGYLNQPELNECLFISDPCYKEEGYRMYRTGDLAVFLPDG
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCEEEEECCC
ELAFVGRKDFQVKYMGYRIELGEIEMVLKSHAAIRDAVVMLREDDPGLKKIVAYCVLEIS
CEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHEEC
GNVSPKELQLFAGRLLPAYMIPAVFVFLKKIPMTPNGKSDRNALPPPGKESFLAGKDDGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TAPESVMERDVAAVLSGILGISAIGVDDNLFSLGAHSLMATRLCSQIRMRWNVNIPLAFV
CCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FENPTVKQIADEIVRKERIGDVPCRITASDAHRTVFPVSLIQKGLWLFQQFQEEGTLFNI
ECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEC
PVVVYFSGAIQEQLIKKSFDFLIDRHECLRTVFELEGEELVQRVLPAMQVELMVKDLSGC
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
NQDTKFAELDRIRKEEGLHRFELDKGPLIKLHLVILGESATHLFITFHHLIIDGWGASVL
CCCCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCCEEEEEEEEHHHCCCCHHHH
FRELAASYDAFSRGNMPALPDKKISFGDFCLWQLERIKSARLSMQIQYWIEQLKGCSFIQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
NIPHDYSRPSMPSFSGARCAFSFSPEITKALNEYCLRNNCTMFMYLMTVFQIFIQRYSGR
HCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
SEIVTGTTIANRNLSDTENIVGLLANSLAIRTDFSGDPKFTELLMQVRKVSLEAFDNQDV
CCEEEEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
PFEIVVENVVQKRERSYHPVFQNLFIFQNTPPPFLHAGDMDFVYEEIGNETAKLDLLLNV
CHHHHHHHHHHHHHCCCCCHHHCEEEEECCCCCCEECCCHHHHHHHHCCCEEEEEEEEEE
EFRKESLFCWIEYNTCLFNADTIERVARDYIWIASHALHETGDPVSSWHFPSIPARNYYA
EECCCEEEEEEEECEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEC
TKDNPLALSCCHYLFELQAERTPDNIAVCCDDVQMTFRELNKKANHLAHRLIQRGVGPDI
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVGLCLTRSVYLAVGILGILKAGGSYVPLDSQYPEERIRYMAHDSGIRLAVTDEASAHVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHH
SFDREMLLVLLDKSDAVESEHSCDNPVFRAGAENTAYIMYTSGTSGRPKGVMVPHRGVSN
HCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCEECCCCCCHH
LAVSAVNNYALKSSDRVLQFFSVSFDGSVEEIFMTLAVGATLVIRTFNAAISVTDFLFHL
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
EKNEITVLDLPTAFWKELVHGVSRTGIKIPNSLRLVIIGGEQASVTDFQKWQKVCGGRVR
CCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEE
LINTYGPTECSAVSVFSEPEKINCSYDFNRGLPIGRPMDNTTLYVVDEHCCLVPFGMPGE
EEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCEEEEECCCCCC
LLIGGAGVAKGYLNLSLLTEDRFIDDVFQESEPKGRLYRTGDIVRSLSDGNLQFLGRKDN
EEEECCHHHCCEEEEEEEECHHHHHHHHHCCCCCCCEEECHHHHHHCCCCCEEEEECCCC
QVKIRGFRIEPGEIESVLNQHELIKQSVVIDLTNDQGETALVGYFVTEKNALSSSELRHY
EEEEEEEEECCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHH
LAQKMPEYMVPSYFVPIKKVPLLPNGKIDRSALPVPDTVVEKKATYVGPRDETEKTLVEI
HHHHCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHCCCCCCCHHHHHHHH
WQEVLGVHPIGVTDDFFELGGHSLLAVRLCSQIQEKVNKKVTLSGLFQSLTIEKLARTIT
HHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHH
DEVWVPESSPAVCIQCVDFGKSLPPLFFIHILGTGLKFCRPMVKYLSPELPVYGLSVHLN
HCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEEEC
EKDHFEEFSVEELATRYVREVRRIYPQGPFLFAGISFGGLIAFEMARKMSEDGEDIRMVA
CCHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEHHH
LIDSILPEAFHKMTGKEGAHAHREKFRSEGVSYLIRKVLERARHEGFVMREKSSHCYSKI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
LLQYYMVRDRVDRMPVSLYEFAARLQNDDALQKYHPKIYTGKVTLFKSRERFYGVSFIQD
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCEEEEEEEEEEECCCHHHCHHHHHH
PLSGWGAFSSGGVEVIDCPGDHLGMLADPHVETLGMKLMQSIETCLHMARPIATSQTGEV
HHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VIRSVKRGESRLFRDISLRSIRESPDAFVATLDQVQHEPLTYWEQLLDFIVDSPLDTIFL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
ACIDQRCIGFAAARIYSNDPYLTELRWMWVDRDFRGKGLGGSLLEKVIEWAQSRGSQKIN
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
LWVSESQNSAIQLYTSKGFVDTGDRGFLRPGSALHARKMIRDNADYLRHGG
EEEECCCCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MKEGITTVENRYGVETPLHYYDISHCLHELFKKQASLNADNPAVIDGTGSLTYRVLDEEA
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECHHH
DNIAQAIVQRGINRGSFIGLCTTRSSQVISGMLGILKAECAYVHLDPEYPSDRLGYIIDD
HHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEC
AGISLILTQQRFTQTFSFCLPSLLLFMDCDQPESYTASIPFSPVEASVSGDPAYVIYTSG
CCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECC
TTGKPKGVCCHHKGVVNLLDEFQQRRYLGSEDRCSWWTNLNFDVSVYEIFSSLLAGSALL
CCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEE
IVPESVRIDGHAFMDWLHVNDITSAYLPPMMVADFLEWVERNPGKSRMRRLLTGVEPIPE
EECCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
NLLLNIQRCVPQLTIINGYGPTETTICATLYTVNSASHHHETTPVGKAVQNMHLHLLDEA
HHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHEEEEECC
GDPVAAGETGEVYIGGVGVSRGYLNQPELNECLFISDPCYKEEGYRMYRTGDLAVFLPDG
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCEEEEECCC
ELAFVGRKDFQVKYMGYRIELGEIEMVLKSHAAIRDAVVMLREDDPGLKKIVAYCVLEIS
CEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHEEC
GNVSPKELQLFAGRLLPAYMIPAVFVFLKKIPMTPNGKSDRNALPPPGKESFLAGKDDGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TAPESVMERDVAAVLSGILGISAIGVDDNLFSLGAHSLMATRLCSQIRMRWNVNIPLAFV
CCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FENPTVKQIADEIVRKERIGDVPCRITASDAHRTVFPVSLIQKGLWLFQQFQEEGTLFNI
ECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEC
PVVVYFSGAIQEQLIKKSFDFLIDRHECLRTVFELEGEELVQRVLPAMQVELMVKDLSGC
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
NQDTKFAELDRIRKEEGLHRFELDKGPLIKLHLVILGESATHLFITFHHLIIDGWGASVL
CCCCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCCEEEEEEEEHHHCCCCHHHH
FRELAASYDAFSRGNMPALPDKKISFGDFCLWQLERIKSARLSMQIQYWIEQLKGCSFIQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
NIPHDYSRPSMPSFSGARCAFSFSPEITKALNEYCLRNNCTMFMYLMTVFQIFIQRYSGR
HCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
SEIVTGTTIANRNLSDTENIVGLLANSLAIRTDFSGDPKFTELLMQVRKVSLEAFDNQDV
CCEEEEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
PFEIVVENVVQKRERSYHPVFQNLFIFQNTPPPFLHAGDMDFVYEEIGNETAKLDLLLNV
CHHHHHHHHHHHHHCCCCCHHHCEEEEECCCCCCEECCCHHHHHHHHCCCEEEEEEEEEE
EFRKESLFCWIEYNTCLFNADTIERVARDYIWIASHALHETGDPVSSWHFPSIPARNYYA
EECCCEEEEEEEECEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEC
TKDNPLALSCCHYLFELQAERTPDNIAVCCDDVQMTFRELNKKANHLAHRLIQRGVGPDI
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVGLCLTRSVYLAVGILGILKAGGSYVPLDSQYPEERIRYMAHDSGIRLAVTDEASAHVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHH
SFDREMLLVLLDKSDAVESEHSCDNPVFRAGAENTAYIMYTSGTSGRPKGVMVPHRGVSN
HCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCEECCCCCCHH
LAVSAVNNYALKSSDRVLQFFSVSFDGSVEEIFMTLAVGATLVIRTFNAAISVTDFLFHL
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
EKNEITVLDLPTAFWKELVHGVSRTGIKIPNSLRLVIIGGEQASVTDFQKWQKVCGGRVR
CCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEE
LINTYGPTECSAVSVFSEPEKINCSYDFNRGLPIGRPMDNTTLYVVDEHCCLVPFGMPGE
EEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCEEEEECCCCCC
LLIGGAGVAKGYLNLSLLTEDRFIDDVFQESEPKGRLYRTGDIVRSLSDGNLQFLGRKDN
EEEECCHHHCCEEEEEEEECHHHHHHHHHCCCCCCCEEECHHHHHHCCCCCEEEEECCCC
QVKIRGFRIEPGEIESVLNQHELIKQSVVIDLTNDQGETALVGYFVTEKNALSSSELRHY
EEEEEEEEECCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHH
LAQKMPEYMVPSYFVPIKKVPLLPNGKIDRSALPVPDTVVEKKATYVGPRDETEKTLVEI
HHHHCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHCCCCCCCHHHHHHHH
WQEVLGVHPIGVTDDFFELGGHSLLAVRLCSQIQEKVNKKVTLSGLFQSLTIEKLARTIT
HHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHH
DEVWVPESSPAVCIQCVDFGKSLPPLFFIHILGTGLKFCRPMVKYLSPELPVYGLSVHLN
HCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEEEC
EKDHFEEFSVEELATRYVREVRRIYPQGPFLFAGISFGGLIAFEMARKMSEDGEDIRMVA
CCHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEHHH
LIDSILPEAFHKMTGKEGAHAHREKFRSEGVSYLIRKVLERARHEGFVMREKSSHCYSKI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
LLQYYMVRDRVDRMPVSLYEFAARLQNDDALQKYHPKIYTGKVTLFKSRERFYGVSFIQD
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCEEEEEEEEEEECCCHHHCHHHHHH
PLSGWGAFSSGGVEVIDCPGDHLGMLADPHVETLGMKLMQSIETCLHMARPIATSQTGEV
HHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VIRSVKRGESRLFRDISLRSIRESPDAFVATLDQVQHEPLTYWEQLLDFIVDSPLDTIFL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
ACIDQRCIGFAAARIYSNDPYLTELRWMWVDRDFRGKGLGGSLLEKVIEWAQSRGSQKIN
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
LWVSESQNSAIQLYTSKGFVDTGDRGFLRPGSALHARKMIRDNADYLRHGG
EEEECCCCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1560782; 2477357 [H]