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The map label for this gene is hetI [H]

Identifier: 119356384

GI number: 119356384

Start: 608005

End: 608736

Strand: Direct

Name: hetI [H]

Synonym: Cpha266_0547

Alternate gene names: 119356384

Gene position: 608005-608736 (Clockwise)

Preceding gene: 119356383

Following gene: 119356391

Centisome position: 19.4

GC content: 45.36

Gene sequence:

>732_bases
ATGAACATGACTCATCAGCGTGTATATGTCTGGCAAATAAATATCGAAGTATTCGAGGAGAACGCGGATGCATTTTTTTC
TCTTTTGTCTTCGGATGAACAGTCAAGAGCAGCGCATTTATCTTTTGCAAGAGATAAGCGAAGCTTTATCGTGAGACGGG
CTTTATTGAGAATGATCCTTGGCTCTTATTGTTCCGTTCATCCTCATCAGTTACGATTCAGGCAGCAGCAATCAGGAAAA
CCCTTTATTGCCTTTCCCGGCCATACAGGAATACATTTCAGTCATGCCCACTCCGTCAATATGGGTCTCTATGCGTTTTC
GCCTGATCAAGCGGTTGGAATTGACGTTGAAAAGATTAGGTCACTACCAGACCTGCTTGTCGTTGCAAGGCGTTTTTTTT
CTTACAGGGAATATGTAATTCTCAAAGGACTTTCCACTCGGAACAGAGAGAGTGTGTTTTTCAGGATGTGGAGTATGAAG
GAGGCTCTGATCAAGGCAAACGGATGGAGCCTTGAAAAGGGGTTGGCCGAATGCTGTACCGCAAAGGTATTCAATAACGA
TTATGGTCGGGTTGCTGATAGTTCAGTGTGTGTCGTCGATAGCGGCTCAGATTTCGCTGCAGCCCTTGCTGTACAAGGGT
GCGGGGAGTATGAGATTTTCTTCGAAAAACCGGATGCCGGCTCTTTTATTTCAGAGCTGATGAGGGATGCTTCTTTCGAT
TGCGGGCATTGA

Upstream 100 bases:

>100_bases
CGATACCGGAGATCGGGGTTTTCTCCGTCCGGGATCGGCATTACACGCAAGAAAGATGATTCGCGATAATGCTGATTATT
TGCGTCATGGAGGATGAAAA

Downstream 100 bases:

>100_bases
TCCGCTTATCGATTGATCAGTTTCATCATGTGTTCAGGATAACGGGCTCCCGCAGCGACTCCTTTTGGCAAGGCTTCGAT
GATATCCGTCATTTCGGTCT

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNMTHQRVYVWQINIEVFEENADAFFSLLSSDEQSRAAHLSFARDKRSFIVRRALLRMILGSYCSVHPHQLRFRQQQSGK
PFIAFPGHTGIHFSHAHSVNMGLYAFSPDQAVGIDVEKIRSLPDLLVVARRFFSYREYVILKGLSTRNRESVFFRMWSMK
EALIKANGWSLEKGLAECCTAKVFNNDYGRVADSSVCVVDSGSDFAAALAVQGCGEYEIFFEKPDAGSFISELMRDASFD
CGH

Sequences:

>Translated_243_residues
MNMTHQRVYVWQINIEVFEENADAFFSLLSSDEQSRAAHLSFARDKRSFIVRRALLRMILGSYCSVHPHQLRFRQQQSGK
PFIAFPGHTGIHFSHAHSVNMGLYAFSPDQAVGIDVEKIRSLPDLLVVARRFFSYREYVILKGLSTRNRESVFFRMWSMK
EALIKANGWSLEKGLAECCTAKVFNNDYGRVADSSVCVVDSGSDFAAALAVQGCGEYEIFFEKPDAGSFISELMRDASFD
CGH
>Mature_243_residues
MNMTHQRVYVWQINIEVFEENADAFFSLLSSDEQSRAAHLSFARDKRSFIVRRALLRMILGSYCSVHPHQLRFRQQQSGK
PFIAFPGHTGIHFSHAHSVNMGLYAFSPDQAVGIDVEKIRSLPDLLVVARRFFSYREYVILKGLSTRNRESVFFRMWSMK
EALIKANGWSLEKGLAECCTAKVFNNDYGRVADSSVCVVDSGSDFAAALAVQGCGEYEIFFEKPDAGSFISELMRDASFD
CGH

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=149, Percent_Identity=24.1610738255034, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 27532; Mature: 27532

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTHQRVYVWQINIEVFEENADAFFSLLSSDEQSRAAHLSFARDKRSFIVRRALLRMIL
CCCCCCEEEEEEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSYCSVHPHQLRFRQQQSGKPFIAFPGHTGIHFSHAHSVNMGLYAFSPDQAVGIDVEKIR
HHHCCCCHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCEEEEECCCCEECCCHHHHH
SLPDLLVVARRFFSYREYVILKGLSTRNRESVFFRMWSMKEALIKANGWSLEKGLAECCT
CCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AKVFNNDYGRVADSSVCVVDSGSDFAAALAVQGCGEYEIFFEKPDAGSFISELMRDASFD
HHHHCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCC
CGH
CCC
>Mature Secondary Structure
MNMTHQRVYVWQINIEVFEENADAFFSLLSSDEQSRAAHLSFARDKRSFIVRRALLRMIL
CCCCCCEEEEEEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSYCSVHPHQLRFRQQQSGKPFIAFPGHTGIHFSHAHSVNMGLYAFSPDQAVGIDVEKIR
HHHCCCCHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCEEEEECCCCEECCCHHHHH
SLPDLLVVARRFFSYREYVILKGLSTRNRESVFFRMWSMKEALIKANGWSLEKGLAECCT
CCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AKVFNNDYGRVADSSVCVVDSGSDFAAALAVQGCGEYEIFFEKPDAGSFISELMRDASFD
HHHHCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCC
CGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]