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The map label for this gene is hup [H]

Identifier: 119356262

GI number: 119356262

Start: 468916

End: 469224

Strand: Reverse

Name: hup [H]

Synonym: Cpha266_0424

Alternate gene names: 119356262

Gene position: 469224-468916 (Counterclockwise)

Preceding gene: 119356263

Following gene: 119356259

Centisome position: 14.97

GC content: 43.69

Gene sequence:

>309_bases
ATGGGAACTACAACTACCAAAGCGGACTTGGTCAATGTCATAGCTCACCGGACAGGCCTTACAAAAAATGAAACGGAAGC
TGTAGTTGACTGCCTTTTTGAAAGTATTATCGATTCGTTGAAATCCGGCAAACGAATCGAAATCAGGGGATTCGGTTCGT
TTAATATTCGCCACAAGAATCTCCGCCAGGCAAGAAATCCGAGAACGGGTGAGAAAGTAACCGTCGACCCGAAAAATGTG
CCGACATTTAAAATCTCAAAAGAGTTCAAACATGCCGTCAGTGAAAGCCTGAAAAACGGTCAAGAGTAA

Upstream 100 bases:

>100_bases
GAAAAGCTTTTGCTGTTTTTACAGGAATTGTTGCGTTTCGTTTGTGGTTTAAATAACTTTATATAAACTATATACAAGAA
CAACCAAAGCAAGACACACC

Downstream 100 bases:

>100_bases
GCGATATCGGTTAACCTCGCCGAGAAATCCCGAAGGGGCATGGAAACATAGGAGTTCCATGCAAATATACCATCCGATGC
ATTCTGGCAACATCGGCAGA

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MGTTTTKADLVNVIAHRTGLTKNETEAVVDCLFESIIDSLKSGKRIEIRGFGSFNIRHKNLRQARNPRTGEKVTVDPKNV
PTFKISKEFKHAVSESLKNGQE

Sequences:

>Translated_102_residues
MGTTTTKADLVNVIAHRTGLTKNETEAVVDCLFESIIDSLKSGKRIEIRGFGSFNIRHKNLRQARNPRTGEKVTVDPKNV
PTFKISKEFKHAVSESLKNGQE
>Mature_101_residues
GTTTTKADLVNVIAHRTGLTKNETEAVVDCLFESIIDSLKSGKRIEIRGFGSFNIRHKNLRQARNPRTGEKVTVDPKNVP
TFKISKEFKHAVSESLKNGQE

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=36.7816091954023, Blast_Score=73, Evalue=3e-15,
Organism=Escherichia coli, GI1788005, Length=88, Percent_Identity=35.2272727272727, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1787141, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 11382; Mature: 11251

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTTTKADLVNVIAHRTGLTKNETEAVVDCLFESIIDSLKSGKRIEIRGFGSFNIRHKN
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHH
LRQARNPRTGEKVTVDPKNVPTFKISKEFKHAVSESLKNGQE
HHHHCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GTTTTKADLVNVIAHRTGLTKNETEAVVDCLFESIIDSLKSGKRIEIRGFGSFNIRHKN
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHH
LRQARNPRTGEKVTVDPKNVPTFKISKEFKHAVSESLKNGQE
HHHHCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA