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The map label for this gene is glmU [H]

Identifier: 119356217

GI number: 119356217

Start: 419788

End: 420531

Strand: Reverse

Name: glmU [H]

Synonym: Cpha266_0378

Alternate gene names: 119356217

Gene position: 420531-419788 (Counterclockwise)

Preceding gene: 119356218

Following gene: 119356199

Centisome position: 13.42

GC content: 49.06

Gene sequence:

>744_bases
ATGTCACTTGCTGTAATCATCATGGCTGCCGGAAAAGGCACCCGTATGCAATCCGAACTTCCGAAAGTACTGCACAAAGC
AAATGGAAGACCGGTTATCGAGTATGTTCTTGACACCGCGCTGCATCTTAAGCCGGAGACTATCATCCTTATTGTCGGCC
ACCAGGCCGACAAAGTCATTGCTGCTACCAGGCAATATCCTGTCATATGCGCACTTCAGGAACCGCAGAACGGAACAGGC
CACGCCGTGATGCAGGCGGAAAAAGCCCTCAAAACGTTTTCCGGCGATGTGTTGATTCTTTCCGGCGATGTGCCGCTTGT
CAAGCGCTCTACCCTTTTACAGCTCATCGCTTTACATCACAATGAGCAGGCATCGGCAACGGTGCTTACCGCACGCCTCG
ATAATCCTTCCGGATATGGGAGGATCATCAGAAATAAAACAGGTGGCGAGGTGATGAAAATCATAGAACAACGGGATGCG
TCACCCGAAGAACTTTCTGTAGACGAGATCAATTCGGGAATATATGTCTTTAAAGCGCCGGTACTTTTCCAGGCACTTCG
TGAGATAACCACCGAAAATGCTCAGCAGGAATACTATCTGACAGACGTTTTTGACATCTGTTTTCGAAACGGCAATAAAG
TCTGCGCCTGTCGTACCGAGAATGCCGATGAAATAAGGGGAATCAATACGCCGGAACAGCTCAGAGAAACCGAACAGCTG
CTTTGCGCTCTGTCACTTTCTTGA

Upstream 100 bases:

>100_bases
GTGCTTATCGTCGACCATCTCAACAACCCCAAACGCAGACATCGCATAGGACAGGAAGACGAACAACTTTCATCATCCAT
TTAATCATCTGTTGTAACTG

Downstream 100 bases:

>100_bases
TCGTCGAGGTTTTTTCTGATCGTTCTCCTCTCTGATTTTGCTGCGATTTCCTGCTGCAAGAGCGTCGGGAGAAATCGGAT
CACACCCACGGCACTCTTTG

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSLAVIIMAAGKGTRMQSELPKVLHKANGRPVIEYVLDTALHLKPETIILIVGHQADKVIAATRQYPVICALQEPQNGTG
HAVMQAEKALKTFSGDVLILSGDVPLVKRSTLLQLIALHHNEQASATVLTARLDNPSGYGRIIRNKTGGEVMKIIEQRDA
SPEELSVDEINSGIYVFKAPVLFQALREITTENAQQEYYLTDVFDICFRNGNKVCACRTENADEIRGINTPEQLRETEQL
LCALSLS

Sequences:

>Translated_247_residues
MSLAVIIMAAGKGTRMQSELPKVLHKANGRPVIEYVLDTALHLKPETIILIVGHQADKVIAATRQYPVICALQEPQNGTG
HAVMQAEKALKTFSGDVLILSGDVPLVKRSTLLQLIALHHNEQASATVLTARLDNPSGYGRIIRNKTGGEVMKIIEQRDA
SPEELSVDEINSGIYVFKAPVLFQALREITTENAQQEYYLTDVFDICFRNGNKVCACRTENADEIRGINTPEQLRETEQL
LCALSLS
>Mature_246_residues
SLAVIIMAAGKGTRMQSELPKVLHKANGRPVIEYVLDTALHLKPETIILIVGHQADKVIAATRQYPVICALQEPQNGTGH
AVMQAEKALKTFSGDVLILSGDVPLVKRSTLLQLIALHHNEQASATVLTARLDNPSGYGRIIRNKTGGEVMKIIEQRDAS
PEELSVDEINSGIYVFKAPVLFQALREITTENAQQEYYLTDVFDICFRNGNKVCACRTENADEIRGINTPEQLRETEQLL
CALSLS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=239, Percent_Identity=37.6569037656904, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 27177; Mature: 27045

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAVIIMAAGKGTRMQSELPKVLHKANGRPVIEYVLDTALHLKPETIILIVGHQADKVI
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
AATRQYPVICALQEPQNGTGHAVMQAEKALKTFSGDVLILSGDVPLVKRSTLLQLIALHH
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHC
NEQASATVLTARLDNPSGYGRIIRNKTGGEVMKIIEQRDASPEELSVDEINSGIYVFKAP
CCCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCHHHHCCCEEEEEHH
VLFQALREITTENAQQEYYLTDVFDICFRNGNKVCACRTENADEIRGINTPEQLRETEQL
HHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHH
LCALSLS
HHHCCCC
>Mature Secondary Structure 
SLAVIIMAAGKGTRMQSELPKVLHKANGRPVIEYVLDTALHLKPETIILIVGHQADKVI
CEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
AATRQYPVICALQEPQNGTGHAVMQAEKALKTFSGDVLILSGDVPLVKRSTLLQLIALHH
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHC
NEQASATVLTARLDNPSGYGRIIRNKTGGEVMKIIEQRDASPEELSVDEINSGIYVFKAP
CCCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCHHHHCCCEEEEEHH
VLFQALREITTENAQQEYYLTDVFDICFRNGNKVCACRTENADEIRGINTPEQLRETEQL
HHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHH
LCALSLS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA