Click here to switch to the map view.

The map label for this gene is fusA [H]

Identifier: 119356069

GI number: 119356069

Start: 245800

End: 247875

Strand: Reverse

Name: fusA [H]

Synonym: Cpha266_0222

Alternate gene names: 119356069

Gene position: 247875-245800 (Counterclockwise)

Preceding gene: 119356082

Following gene: 119356065

Centisome position: 7.91

GC content: 46.97

Gene sequence:

>2076_bases
ATGCAATCCATTCAACCGGATCAATTGAGAAACATCGTCATCACTGGTCATGCCGGAGCAGGCAAGACTATCCTCTGCGA
ATCGCTTGCCCTTGCCATGGGAGTAACGAACCGTCTCGGCAGCATTGATGACGGAACAACGCTTTCCGACTATTCAGCCG
AAGAGGTACAAAGAAAGCACAGCTTAAACACAAGTGTTATTCATGGATTCTGGAATGATAAAAAAATAAATATCATCGAC
ACCCCGGGACTGCTTGATTTTCAGGGCGATGTCAAATCCGCAATGCGTGTAGCTGATACCGTGTTAATCACGGTAAACGC
GGCGAATGGTGTCGAGGTCGGAACAGATGCCACCTGGGATTATACGAAAGAGTACCACAAACCGACCATGTTTGTCCTTT
CCAGACTCGATGCCGACAGAACAAACTTCAATAATACTCTTGAGGAGCTCAGGGATCATTTCGGCCACCTCGTCACGCCC
ATACAGTTTCCTGCTGAAGAGGGTCTGGGTCATCACATCCTTATTGACGTTCTCATGATGAAGCAACTCGAATTCAGTCC
TGACAGGCCCGGAAATATGACTATTTCGACTATTCCGGATCTCTATCTTAAACGCGCAGAGGAGATGCATCAGCAACTTG
TAGAGGCCGTCGCTGAAACTGATGAGGAGTTGATGAACCGGTACTTTGAAGTTGGCAACCTGACAGAAGAGGAACTCCGA
ACGGGCATCAAATCCGCACTGCTGACAAGAACATTCTTTCCCGTTTTCTGTACCTCGCCGCTTCACCTTATTGGAACAGA
ACGACTGCTGAATATCATTGTCAATCTCTGCCCGTCACCGATCGAGCGAGGTCCTGAGCATGCGCTCTGCTCTCTTGACG
ATACCGAAAGACTTCTGCAACCTGATCCTGATGGACCTACCATTGCCTTTATTTTCAAAACCATGTCGGAACCAAGAGTA
GGCGAGATATCATATCTTCGCGTCTATTCAGGTCATCTTGAAACCGGGCATGAACTGATAGACGTTCAGACCGGACAACC
TGAAAAAATAGGTCAGGTCTATACCATAATCGGCCAGAAAAAAACACCTGTTGAAAAACTTCTCGCCGGAGATATCGGAA
TGGTGGTCAAACTCAAGGATGCACATACCAACGATACCCTTGCCGATAAAGGGAGCAACTGCCGCATCAGCCCTATACTC
TTCCCCGTTCCGGTACTTGCTTCAGCTATTATTCCCGTTACGCAGGGTGACGAAGAAAAAATTTCCGCAGGTCTTCATCA
TCTTCATGAGGAGGATCCGAGCTTCACCATCATGCATGATGTGGAATTCAACCAGACAATACTTAAAACCTTCGGTGAAA
CGCACCTTGAAATTATCATCAGCAGACTGCAGAACAAGTTCAACGTGACTGTCGAAATTGCGCCCATAAAAATCCCTTAT
CGCGAAACCATAAGAGTAACTTCAACAGCGCAGGGTAAATACAAAAAACAGTCCGGAGGCAGAGGCCAGTATGGTGATGT
ATGGGTACGACTTGAACCCAAAGAGAGAGACTCCGGATTTGAATTCAGCAGCGAAGTGGTTGGAGGAGTTGTGCCTACCC
GATATATCCCTGCAGTAGAAAAAGGGCTGCGCGAATCAATCGAAGCCGGCGTTCTTGCTGGATACCCGGTTGTCGACATG
AAAGCAATTGTTTATGACGGCTCTTTTCATCCTGTCGACAGCTCTGAGTTTGCCTTTAAAATTGCTGCAAGCATGGCATT
CAAAGCAGCATTCGATAAAGCCAAACCACTGCTTCTTGAGCCATTTTATGAACTGAATGTTTTTGCCCCCGAACAATATA
CCGGAGAAATCGTAGGTGAAATATCAAGTAAACGGGGTAAAATTCTTGGCATGGACACTGATGCTCGCTTCCAGATTGTC
AAAGCCCTCATTCCGCAGGCAGCACTGACATCATTTCATCATGCGCTAATCCGCCTGACCCAGAGTCGCGCGCGTTATAC
GTATAAATTCAACCATTATGAAGAAGCGCCGCCGGAGATAGTAAAACAGGTTACTTCCGAAAAATCAGTGGCATAA

Upstream 100 bases:

>100_bases
ATTACCTATCAAGCTATCACTGGATGCCCTAAGGCAGCATTATATCGCGGTACAACCGGCTTCTGCAAGAGCACCCTCAA
TTCAACAAAGGAGTCCTTCC

Downstream 100 bases:

>100_bases
AAATGCTCCGTGAAGGAATTCTTTCTTTTGATGAAACAATTCCTTCACGGGTTTTTTTGCCGGTCAATCCGCGCCTGTTT
GTTAACGCAATCTTTTAACG

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MQSIQPDQLRNIVITGHAGAGKTILCESLALAMGVTNRLGSIDDGTTLSDYSAEEVQRKHSLNTSVIHGFWNDKKINIID
TPGLLDFQGDVKSAMRVADTVLITVNAANGVEVGTDATWDYTKEYHKPTMFVLSRLDADRTNFNNTLEELRDHFGHLVTP
IQFPAEEGLGHHILIDVLMMKQLEFSPDRPGNMTISTIPDLYLKRAEEMHQQLVEAVAETDEELMNRYFEVGNLTEEELR
TGIKSALLTRTFFPVFCTSPLHLIGTERLLNIIVNLCPSPIERGPEHALCSLDDTERLLQPDPDGPTIAFIFKTMSEPRV
GEISYLRVYSGHLETGHELIDVQTGQPEKIGQVYTIIGQKKTPVEKLLAGDIGMVVKLKDAHTNDTLADKGSNCRISPIL
FPVPVLASAIIPVTQGDEEKISAGLHHLHEEDPSFTIMHDVEFNQTILKTFGETHLEIIISRLQNKFNVTVEIAPIKIPY
RETIRVTSTAQGKYKKQSGGRGQYGDVWVRLEPKERDSGFEFSSEVVGGVVPTRYIPAVEKGLRESIEAGVLAGYPVVDM
KAIVYDGSFHPVDSSEFAFKIAASMAFKAAFDKAKPLLLEPFYELNVFAPEQYTGEIVGEISSKRGKILGMDTDARFQIV
KALIPQAALTSFHHALIRLTQSRARYTYKFNHYEEAPPEIVKQVTSEKSVA

Sequences:

>Translated_691_residues
MQSIQPDQLRNIVITGHAGAGKTILCESLALAMGVTNRLGSIDDGTTLSDYSAEEVQRKHSLNTSVIHGFWNDKKINIID
TPGLLDFQGDVKSAMRVADTVLITVNAANGVEVGTDATWDYTKEYHKPTMFVLSRLDADRTNFNNTLEELRDHFGHLVTP
IQFPAEEGLGHHILIDVLMMKQLEFSPDRPGNMTISTIPDLYLKRAEEMHQQLVEAVAETDEELMNRYFEVGNLTEEELR
TGIKSALLTRTFFPVFCTSPLHLIGTERLLNIIVNLCPSPIERGPEHALCSLDDTERLLQPDPDGPTIAFIFKTMSEPRV
GEISYLRVYSGHLETGHELIDVQTGQPEKIGQVYTIIGQKKTPVEKLLAGDIGMVVKLKDAHTNDTLADKGSNCRISPIL
FPVPVLASAIIPVTQGDEEKISAGLHHLHEEDPSFTIMHDVEFNQTILKTFGETHLEIIISRLQNKFNVTVEIAPIKIPY
RETIRVTSTAQGKYKKQSGGRGQYGDVWVRLEPKERDSGFEFSSEVVGGVVPTRYIPAVEKGLRESIEAGVLAGYPVVDM
KAIVYDGSFHPVDSSEFAFKIAASMAFKAAFDKAKPLLLEPFYELNVFAPEQYTGEIVGEISSKRGKILGMDTDARFQIV
KALIPQAALTSFHHALIRLTQSRARYTYKFNHYEEAPPEIVKQVTSEKSVA
>Mature_691_residues
MQSIQPDQLRNIVITGHAGAGKTILCESLALAMGVTNRLGSIDDGTTLSDYSAEEVQRKHSLNTSVIHGFWNDKKINIID
TPGLLDFQGDVKSAMRVADTVLITVNAANGVEVGTDATWDYTKEYHKPTMFVLSRLDADRTNFNNTLEELRDHFGHLVTP
IQFPAEEGLGHHILIDVLMMKQLEFSPDRPGNMTISTIPDLYLKRAEEMHQQLVEAVAETDEELMNRYFEVGNLTEEELR
TGIKSALLTRTFFPVFCTSPLHLIGTERLLNIIVNLCPSPIERGPEHALCSLDDTERLLQPDPDGPTIAFIFKTMSEPRV
GEISYLRVYSGHLETGHELIDVQTGQPEKIGQVYTIIGQKKTPVEKLLAGDIGMVVKLKDAHTNDTLADKGSNCRISPIL
FPVPVLASAIIPVTQGDEEKISAGLHHLHEEDPSFTIMHDVEFNQTILKTFGETHLEIIISRLQNKFNVTVEIAPIKIPY
RETIRVTSTAQGKYKKQSGGRGQYGDVWVRLEPKERDSGFEFSSEVVGGVVPTRYIPAVEKGLRESIEAGVLAGYPVVDM
KAIVYDGSFHPVDSSEFAFKIAASMAFKAAFDKAKPLLLEPFYELNVFAPEQYTGEIVGEISSKRGKILGMDTDARFQIV
KALIPQAALTSFHHALIRLTQSRARYTYKFNHYEEAPPEIVKQVTSEKSVA

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=696, Percent_Identity=29.8850574712644, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI19923640, Length=712, Percent_Identity=25.4213483146067, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI25306287, Length=692, Percent_Identity=25.4335260115607, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI25306283, Length=391, Percent_Identity=27.8772378516624, Blast_Score=147, Evalue=4e-35,
Organism=Escherichia coli, GI1789738, Length=692, Percent_Identity=35.5491329479769, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1790835, Length=478, Percent_Identity=24.2677824267782, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=693, Percent_Identity=25.974025974026, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17556745, Length=709, Percent_Identity=24.1184767277856, Blast_Score=175, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6323098, Length=703, Percent_Identity=27.4537695590327, Blast_Score=302, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6322359, Length=781, Percent_Identity=24.583866837388, Blast_Score=234, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24582462, Length=694, Percent_Identity=28.6743515850144, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI221458488, Length=708, Percent_Identity=23.5875706214689, Blast_Score=197, Evalue=2e-50,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 76871; Mature: 76871

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSIQPDQLRNIVITGHAGAGKTILCESLALAMGVTNRLGSIDDGTTLSDYSAEEVQRKH
CCCCCCCHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
SLNTSVIHGFWNDKKINIIDTPGLLDFQGDVKSAMRVADTVLITVNAANGVEVGTDATWD
CCCCCEEEECCCCCEEEEEECCCCEECCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCH
YTKEYHKPTMFVLSRLDADRTNFNNTLEELRDHFGHLVTPIQFPAEEGLGHHILIDVLMM
HHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHH
KQLEFSPDRPGNMTISTIPDLYLKRAEEMHQQLVEAVAETDEELMNRYFEVGNLTEEELR
HHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TGIKSALLTRTFFPVFCTSPLHLIGTERLLNIIVNLCPSPIERGPEHALCSLDDTERLLQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEECCCCHHHHCC
PDPDGPTIAFIFKTMSEPRVGEISYLRVYSGHLETGHELIDVQTGQPEKIGQVYTIIGQK
CCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHCCEEEEECCC
KTPVEKLLAGDIGMVVKLKDAHTNDTLADKGSNCRISPILFPVPVLASAIIPVTQGDEEK
CCCHHHHHCCCCCEEEEEECCCCCCCHHCCCCCCEECEEECCHHHHHHHHCCCCCCCHHH
ISAGLHHLHEEDPSFTIMHDVEFNQTILKTFGETHLEIIISRLQNKFNVTVEIAPIKIPY
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEEEECCH
RETIRVTSTAQGKYKKQSGGRGQYGDVWVRLEPKERDSGFEFSSEVVGGVVPTRYIPAVE
HHEEEEEECCCCCHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHH
KGLRESIEAGVLAGYPVVDMKAIVYDGSFHPVDSSEFAFKIAASMAFKAAFDKAKPLLLE
HHHHHHHHCCCCCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEC
PFYELNVFAPEQYTGEIVGEISSKRGKILGMDTDARFQIVKALIPQAALTSFHHALIRLT
CCHHCEEECCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRARYTYKFNHYEEAPPEIVKQVTSEKSVA
HHHCEEEEEECCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MQSIQPDQLRNIVITGHAGAGKTILCESLALAMGVTNRLGSIDDGTTLSDYSAEEVQRKH
CCCCCCCHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
SLNTSVIHGFWNDKKINIIDTPGLLDFQGDVKSAMRVADTVLITVNAANGVEVGTDATWD
CCCCCEEEECCCCCEEEEEECCCCEECCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCH
YTKEYHKPTMFVLSRLDADRTNFNNTLEELRDHFGHLVTPIQFPAEEGLGHHILIDVLMM
HHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHH
KQLEFSPDRPGNMTISTIPDLYLKRAEEMHQQLVEAVAETDEELMNRYFEVGNLTEEELR
HHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TGIKSALLTRTFFPVFCTSPLHLIGTERLLNIIVNLCPSPIERGPEHALCSLDDTERLLQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEECCCCHHHHCC
PDPDGPTIAFIFKTMSEPRVGEISYLRVYSGHLETGHELIDVQTGQPEKIGQVYTIIGQK
CCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHCCEEEEECCC
KTPVEKLLAGDIGMVVKLKDAHTNDTLADKGSNCRISPILFPVPVLASAIIPVTQGDEEK
CCCHHHHHCCCCCEEEEEECCCCCCCHHCCCCCCEECEEECCHHHHHHHHCCCCCCCHHH
ISAGLHHLHEEDPSFTIMHDVEFNQTILKTFGETHLEIIISRLQNKFNVTVEIAPIKIPY
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEEEECCH
RETIRVTSTAQGKYKKQSGGRGQYGDVWVRLEPKERDSGFEFSSEVVGGVVPTRYIPAVE
HHEEEEEECCCCCHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHH
KGLRESIEAGVLAGYPVVDMKAIVYDGSFHPVDSSEFAFKIAASMAFKAAFDKAKPLLLE
HHHHHHHHCCCCCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEC
PFYELNVFAPEQYTGEIVGEISSKRGKILGMDTDARFQIVKALIPQAALTSFHHALIRLT
CCHHCEEECCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRARYTYKFNHYEEAPPEIVKQVTSEKSVA
HHHCEEEEEECCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA